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The map label for this gene is xylB [H]

Identifier: 145294232

GI number: 145294232

Start: 206006

End: 207388

Strand: Direct

Name: xylB [H]

Synonym: cgR_0188

Alternate gene names: 145294232

Gene position: 206006-207388 (Clockwise)

Preceding gene: 145294231

Following gene: 145294237

Centisome position: 6.22

GC content: 59.51

Gene sequence:

>1383_bases
ATGGCTTTGGTTCTTGGAATCGATAGTTCCACCCAATCCTGCAAGGCTTTGCTTGTCGACGCCGCCACCGGCCAGGTTAT
CGACGAAGGCCGCGCGAGTCACCCGAGCGGGTCGGAGGTAGATCCACGTGCGTGGATCGCTGCGCTGGATCAAGCTACCG
AGGGGTTGTTAGAACGCGCGGACGCTGTATCTATTGCAGGCCAGCAGCACGGCATGGTGGCGTTGGATGAAAACGATGAA
ATCGTTCGCCCGGCGTTGTTATGGAATGACACTCGTTCTGCCCAGGCTGCGTTGGATCTCAATGAGGAGATCGGCGGCGA
TCAGGCTGCGGTAGATGCCACGGGAAGTGTGTATGTTGCTTCTTTAACTGCCACCAAAATGCGGTGGATGCGTGACCATG
AGCCAGAAAATGCAGCGCGCACGGCGTCGGTGATGTTGCCTCATGATTTCCTCACCTGGCATTTGATGGGACGCGGACGC
AAAGTCACCGATCATGGTGATGCCTCCGGAACGGGTTATTACAGCACGCGCGATCGTGCGTGGCGCACCGATCTAGCTGC
CTGGGCGCTGGGCCATGAGGTGGAACTTCCTGAACTCCTGGCCCCAAATGCGATTGCGGGAACAACTCCAGGTGGCGTGA
AAGTTGCTGCAGGCACGGGAGATAATGCTGCGGCTGCGCTTGGCCTTGATTTGCAGCCTGGCGATGTCAGCGTGTCGATC
GGCACCTCTGGCGTTGCCGGCATGACCGTTCAAAATAGCGTCCACGATACATCTGGTTTGGTCACTGGTTTCGCCGATGC
CACGGGTGCGTATTTCCCGCTGGCCTGCACGCTTAATGGCGCACCGGTGTTGGAATTCGGCCGCCGCATTCTGGGCGTGG
AATGGGAAGAGTTCGATGCGCTTGCACTGGCTGCTCAACCCGGTTCAGGTGGCGTCACGCTCCAGCCTTATTTGGAGGGC
GAGCGTACGCCGAATCGTCCCGCAGCACGTGGCGTTTTGGCTGGACTAAACAGTGCAACCACCCGCGAGGACTTTGCCCG
AGCAACTGTTGAAGGCTTGTTGTTGGCATTGGATGATGCTGTAACCGCCCTGGTTGAGGCCACGGGAGTGCCCGTTCAGC
GCATCCAGCTCATCGGTGGCGGCGCGCGTTCACAGGCGGTTCGTGAGATCGCCCCTGAGATTTTCGGCCATGAGATTGTG
GTTCCAGAACCCGCTGAATATGTGGCGTTGGGTGCAGCTCGTCAGGCGGCATGGGCGCTGTCCGGTGAGGCCACGCCACC
GCAGTGGCCAACTCCCGGTTCCGATCCGCACCGCGCACCCAAAAACACTGAGCTGAGCACGCGTTATGCGAAGCTGCGTG
CTGCAACGCAGGGTTGGTACTAG

Upstream 100 bases:

>100_bases
GAGCAGCGGGATCTTTTGCGTAATTCGCGCGCGCAGATCCATGTGATTGACCACAATGGTGATGAAATTTTGGATACCCC
AACGGAAGAGGATTTTTAAG

Downstream 100 bases:

>100_bases
AGCTCGATATTGTCGATCAACCGCACCGGCCCCACGAAAATCGCCGCGACCACCAACGCTGGTTGGGTGAGCAGGCCGTC
GATTTCTAATGGTTCGAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERADAVSIAGQQHGMVALDENDE
IVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVASLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGR
KVTDHGDASGTGYYSTRDRAWRTDLAAWALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
GTSGVAGMTVQNSVHDTSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDALALAAQPGSGGVTLQPYLEG
ERTPNRPAARGVLAGLNSATTREDFARATVEGLLLALDDAVTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIV
VPEPAEYVALGAARQAAWALSGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY

Sequences:

>Translated_460_residues
MALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERADAVSIAGQQHGMVALDENDE
IVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVASLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGR
KVTDHGDASGTGYYSTRDRAWRTDLAAWALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
GTSGVAGMTVQNSVHDTSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDALALAAQPGSGGVTLQPYLEG
ERTPNRPAARGVLAGLNSATTREDFARATVEGLLLALDDAVTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIV
VPEPAEYVALGAARQAAWALSGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY
>Mature_459_residues
ALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERADAVSIAGQQHGMVALDENDEI
VRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVASLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGRK
VTDHGDASGTGYYSTRDRAWRTDLAAWALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSIG
TSGVAGMTVQNSVHDTSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDALALAAQPGSGGVTLQPYLEGE
RTPNRPAARGVLAGLNSATTREDFARATVEGLLLALDDAVTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIVV
PEPAEYVALGAARQAAWALSGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=443, Percent_Identity=23.9277652370203, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI189409120, Length=443, Percent_Identity=23.9277652370203, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4504007, Length=443, Percent_Identity=23.9277652370203, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI42794763, Length=449, Percent_Identity=23.6080178173719, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI18860918, Length=482, Percent_Identity=23.6514522821577, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1789987, Length=490, Percent_Identity=31.4285714285714, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790361, Length=451, Percent_Identity=25.0554323725055, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790005, Length=375, Percent_Identity=23.7333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554530, Length=473, Percent_Identity=23.2558139534884, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=447, Percent_Identity=25.9507829977629, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356607, Length=494, Percent_Identity=24.8987854251012, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920476, Length=432, Percent_Identity=23.6111111111111, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24655555, Length=414, Percent_Identity=22.7053140096618, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655560, Length=414, Percent_Identity=22.7053140096618, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655570, Length=414, Percent_Identity=22.7053140096618, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655574, Length=414, Percent_Identity=22.7053140096618, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655565, Length=414, Percent_Identity=22.7053140096618, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 48099; Mature: 47968

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERA
CEEEEECCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DAVSIAGQQHGMVALDENDEIVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVA
HHHEECCCCCCEEEECCCCCEECCEEEECCCCCCCEEECCHHHCCCCCEEEECCCCEEEE
SLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGRKVTDHGDASGTGYYSTRDRA
EHHHHHHHHHHCCCCCCHHHEEEEEECCHHEEEEEECCCCEECCCCCCCCCCCCCCCCCH
WRTDLAAWALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
HHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEE
GTSGVAGMTVQNSVHDTSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDA
CCCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHHCHHHHCCCHHHCCE
LALAAQPGSGGVTLQPYLEGERTPNRPAARGVLAGLNSATTREDFARATVEGLLLALDDA
EEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIVVPEPAEYVALGAARQAAWAL
HHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHCCHHHHHEEE
SGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALVLGIDSSTQSCKALLVDAATGQVIDEGRASHPSGSEVDPRAWIAALDQATEGLLERA
EEEEECCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DAVSIAGQQHGMVALDENDEIVRPALLWNDTRSAQAALDLNEEIGGDQAAVDATGSVYVA
HHHEECCCCCCEEEECCCCCEECCEEEECCCCCCCEEECCHHHCCCCCEEEECCCCEEEE
SLTATKMRWMRDHEPENAARTASVMLPHDFLTWHLMGRGRKVTDHGDASGTGYYSTRDRA
EHHHHHHHHHHCCCCCCHHHEEEEEECCHHEEEEEECCCCEECCCCCCCCCCCCCCCCCH
WRTDLAAWALGHEVELPELLAPNAIAGTTPGGVKVAAGTGDNAAAALGLDLQPGDVSVSI
HHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEE
GTSGVAGMTVQNSVHDTSGLVTGFADATGAYFPLACTLNGAPVLEFGRRILGVEWEEFDA
CCCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHHCHHHHCCCHHHCCE
LALAAQPGSGGVTLQPYLEGERTPNRPAARGVLAGLNSATTREDFARATVEGLLLALDDA
EEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VTALVEATGVPVQRIQLIGGGARSQAVREIAPEIFGHEIVVPEPAEYVALGAARQAAWAL
HHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHCCHHHHHEEE
SGEATPPQWPTPGSDPHRAPKNTELSTRYAKLRAATQGWY
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]