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The map label for this gene is ycgO [H]

Identifier: 138897013

GI number: 138897013

Start: 3491050

End: 3492507

Strand: Reverse

Name: ycgO [H]

Synonym: GTNG_3384

Alternate gene names: 138897013

Gene position: 3492507-3491050 (Counterclockwise)

Preceding gene: 138897017

Following gene: 138897008

Centisome position: 98.37

GC content: 50.82

Gene sequence:

>1458_bases
ATGGTTTTATTTTCCGTCATTGTTTATTTAGTTGGCATGCTTTGGATCGGTTATTGGGCGTATAAACGGACGTCCAACTT
GTCCGATTATGTGCTCGGCGGTCGGACGCTCGGACCAGCGGTCACCGCGTTGAGCGCTGGGGCTTCCGATATGAGTGGCT
GGCTGTTGATGGGGTTGCCAGGAGCGATGTATCTTGACGGGGTGAGCGCCGCTTGGATTGCCATCGGGCTGACGCTAGGC
GCTTATGCGAACTGGCTGTATGTTGCGCCGCGGCTGCGTGTTTATACAGAAGTAGCGAACGACTCGATTACGATTCCGGA
ATTTTTAGAAAATCGCTTCAGCGATACGACGAAATTGTTGCGGATGGTGTCTGGGATTGTCATTATGATCTTTTTCACGT
TTTACGTTTCATCCGGTCTTGTCTCAGGTGGTGTGTTGTTTGAGAACTCGTTTGGGGTCAGCTACCATACGGGGTTATGG
ATCGTCGGCGGTGTTGTCGTTGCTTATACGTTGTTCGGCGGCTTTTTGGCGGTCAGCTGGACGGACTTTGTACAAGGGAC
CATCATGTTTATCGCTCTCATTCTTGTCCCGGCTGTGACACTGTTTCACACAGGTGGGCCGGTTGATACGATCGAGACGA
TTCGCGACATTGATCCAGCTTTGTTAGATCTGTGGAAAGGAACGAGTTTTCTCGGGATTATTTCATTATTCGCTTGGGGG
CTTGGTTATTTTGGACAACCGCACATTATCGTCCGTTTTATGGCCATTAAATCGGTCAAAGAAATGAAAAGCGCCCGTCG
CATTGGCATGGGCTGGATGATTTTTTCAATCGTTGGGGCTATGCTGACAGGTCTTTTTGGAATCGCTTACTTTTCGCAAC
GCGGCATGAAGCTCGATGACCCGGAAACGGTGTTTATCCAACTTGGTGAAATTTTGTTCCATCCAATCATCACGGGATTT
TTGCTGGCGGCGATTTTGGCAGCGATCATGAGCACGATTTCCTCACAGCTGCTTGTCACGTCCAGCTCGCTGACTGAAGA
TTTGTATAAAGTGCTGTTCCGCCGCTCGGCTTCAGACAAGGAGCTTGTCCTTGTCGGCCGCCTGTCGGTGCTCGTTGTCG
CCATTGTCGCGACCGCGTTGGCATACACGAAAAACGATACCATTTTAAACTTGGTCGGCTATGCGTGGGCTGGGTTTGGC
GCGTCATTTGGCCCGGTTATTTTGCTAAGCTTGTTTTGGCGGCGAATGACGAAATGGGGAGCGTTCGCCGGCATGGTCGC
TGGAGCGATGACAGTCATCCTCTGGACGCAATCAGACTACTTAAAAGGGCTGCTGTATGAAATGATCCCGGGATTTGCCG
CAAGCTTGCTTGCCATTGTCGTGGTGAGCTTGCTGACGAAGGCACCGGAAGGGAAAGTGGCCGAGCAATTTGACCGGTTT
AAACAGTCGCTGTCATAA

Upstream 100 bases:

>100_bases
TACTATAGCGATATGGAAAAAAATAAATACTATTGTGTAAATACTATCGATTTCGTTATGATGAAAGTGATGACAAGACA
GCAAAGGAAGGAGAGTCTTC

Downstream 100 bases:

>100_bases
GCAAGACAAACAGGGTGTCCTTTGTCGTAGGGACACCCTGTTGTCAATGAGATATTTTGTATGTCCCGACTCAAGTACAG
GTGTTGTCGCGACACCATGT

Product: Sodium/proline symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MVLFSVIVYLVGMLWIGYWAYKRTSNLSDYVLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMYLDGVSAAWIAIGLTLG
AYANWLYVAPRLRVYTEVANDSITIPEFLENRFSDTTKLLRMVSGIVIMIFFTFYVSSGLVSGGVLFENSFGVSYHTGLW
IVGGVVVAYTLFGGFLAVSWTDFVQGTIMFIALILVPAVTLFHTGGPVDTIETIRDIDPALLDLWKGTSFLGIISLFAWG
LGYFGQPHIIVRFMAIKSVKEMKSARRIGMGWMIFSIVGAMLTGLFGIAYFSQRGMKLDDPETVFIQLGEILFHPIITGF
LLAAILAAIMSTISSQLLVTSSSLTEDLYKVLFRRSASDKELVLVGRLSVLVVAIVATALAYTKNDTILNLVGYAWAGFG
ASFGPVILLSLFWRRMTKWGAFAGMVAGAMTVILWTQSDYLKGLLYEMIPGFAASLLAIVVVSLLTKAPEGKVAEQFDRF
KQSLS

Sequences:

>Translated_485_residues
MVLFSVIVYLVGMLWIGYWAYKRTSNLSDYVLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMYLDGVSAAWIAIGLTLG
AYANWLYVAPRLRVYTEVANDSITIPEFLENRFSDTTKLLRMVSGIVIMIFFTFYVSSGLVSGGVLFENSFGVSYHTGLW
IVGGVVVAYTLFGGFLAVSWTDFVQGTIMFIALILVPAVTLFHTGGPVDTIETIRDIDPALLDLWKGTSFLGIISLFAWG
LGYFGQPHIIVRFMAIKSVKEMKSARRIGMGWMIFSIVGAMLTGLFGIAYFSQRGMKLDDPETVFIQLGEILFHPIITGF
LLAAILAAIMSTISSQLLVTSSSLTEDLYKVLFRRSASDKELVLVGRLSVLVVAIVATALAYTKNDTILNLVGYAWAGFG
ASFGPVILLSLFWRRMTKWGAFAGMVAGAMTVILWTQSDYLKGLLYEMIPGFAASLLAIVVVSLLTKAPEGKVAEQFDRF
KQSLS
>Mature_485_residues
MVLFSVIVYLVGMLWIGYWAYKRTSNLSDYVLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMYLDGVSAAWIAIGLTLG
AYANWLYVAPRLRVYTEVANDSITIPEFLENRFSDTTKLLRMVSGIVIMIFFTFYVSSGLVSGGVLFENSFGVSYHTGLW
IVGGVVVAYTLFGGFLAVSWTDFVQGTIMFIALILVPAVTLFHTGGPVDTIETIRDIDPALLDLWKGTSFLGIISLFAWG
LGYFGQPHIIVRFMAIKSVKEMKSARRIGMGWMIFSIVGAMLTGLFGIAYFSQRGMKLDDPETVFIQLGEILFHPIITGF
LLAAILAAIMSTISSQLLVTSSSLTEDLYKVLFRRSASDKELVLVGRLSVLVVAIVATALAYTKNDTILNLVGYAWAGFG
ASFGPVILLSLFWRRMTKWGAFAGMVAGAMTVILWTQSDYLKGLLYEMIPGFAASLLAIVVVSLLTKAPEGKVAEQFDRF
KQSLS

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=487, Percent_Identity=56.2628336755647, Blast_Score=542, Evalue=1e-154,
Organism=Homo sapiens, GI4507031, Length=538, Percent_Identity=23.4200743494424, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI110835708, Length=545, Percent_Identity=24.0366972477064, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI206597483, Length=379, Percent_Identity=25.5936675461741, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI14140236, Length=477, Percent_Identity=21.1740041928721, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI109659836, Length=377, Percent_Identity=23.8726790450928, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4507035, Length=372, Percent_Identity=23.6559139784946, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI206597487, Length=500, Percent_Identity=24.4, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787251, Length=480, Percent_Identity=55.2083333333333, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI87082237, Length=441, Percent_Identity=27.891156462585, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790503, Length=432, Percent_Identity=24.3055555555556, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790113, Length=490, Percent_Identity=24.2857142857143, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539284, Length=421, Percent_Identity=22.3277909738717, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533094, Length=381, Percent_Identity=23.6220472440945, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640370, Length=349, Percent_Identity=26.3610315186246, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221459588, Length=385, Percent_Identity=24.4155844155844, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651739, Length=474, Percent_Identity=23.6286919831224, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24645928, Length=365, Percent_Identity=26.5753424657534, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648033, Length=394, Percent_Identity=23.0964467005076, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356865, Length=394, Percent_Identity=23.0964467005076, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221459584, Length=358, Percent_Identity=22.3463687150838, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221459586, Length=386, Percent_Identity=23.8341968911917, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362918, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573698, Length=409, Percent_Identity=23.7163814180929, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650192, Length=355, Percent_Identity=22.5352112676056, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24651741, Length=464, Percent_Identity=25.4310344827586, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 52835; Mature: 52835

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLFSVIVYLVGMLWIGYWAYKRTSNLSDYVLGGRTLGPAVTALSAGASDMSGWLLMGLP
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCC
GAMYLDGVSAAWIAIGLTLGAYANWLYVAPRLRVYTEVANDSITIPEFLENRFSDTTKLL
CHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
RMVSGIVIMIFFTFYVSSGLVSGGVLFENSFGVSYHTGLWIVGGVVVAYTLFGGFLAVSW
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHH
TDFVQGTIMFIALILVPAVTLFHTGGPVDTIETIRDIDPALLDLWKGTSFLGIISLFAWG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHH
LGYFGQPHIIVRFMAIKSVKEMKSARRIGMGWMIFSIVGAMLTGLFGIAYFSQRGMKLDD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PETVFIQLGEILFHPIITGFLLAAILAAIMSTISSQLLVTSSSLTEDLYKVLFRRSASDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ELVLVGRLSVLVVAIVATALAYTKNDTILNLVGYAWAGFGASFGPVILLSLFWRRMTKWG
CEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AFAGMVAGAMTVILWTQSDYLKGLLYEMIPGFAASLLAIVVVSLLTKAPEGKVAEQFDRF
HHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
KQSLS
HHHCC
>Mature Secondary Structure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HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]