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The map label for this gene is ywlC [H]

Identifier: 138896951

GI number: 138896951

Start: 3425925

End: 3426962

Strand: Reverse

Name: ywlC [H]

Synonym: GTNG_3320

Alternate gene names: 138896951

Gene position: 3426962-3425925 (Counterclockwise)

Preceding gene: 138896952

Following gene: 138896950

Centisome position: 96.53

GC content: 57.9

Gene sequence:

>1038_bases
TTGAAAACGCATGTTTGGGTTGTGGATAATATTGTTGATAAACAGCAAATTTATCCACAAATACAAGAGGCTGCCGAATG
GTTGCGGACCGGAGAAGTGATCGCATTTCCAACGGAAACGGTGTACGGATTGGGAGCAGATGCGGCTAATACGACAGCGG
TGGAAAAAATTTTTGCCGCCAAAGGACGGCCGAGCGACAATCCGCTCATCGTCCACGTCGCCAGCCTCGCGCAAGTTGAA
TCGATCGCTGCATCGATCCCGCCGGTCGCGAAAACGTTAATGGAACGGTTTTGGCCGGGCCCGCTCACCTTAGTGTTGCC
GAAACGGGACGGAGCGGTGTCTGAACGGGTGACAGCTGGTCTTTCGACCGTGGCGGTGCGCATGCCGGATCATCCACTGG
CGCTTGCCTTGATCGAAGCGAGCGGCTTAGCGCTTGCCGCCCCGAGCGCCAACCGGTCAGGAAGGCCAAGCCCGACGACG
GCCGCCCACGTGCTCGCTGATTTGAACGGGCGCATTGCCGGAGTGATTGATGGCGGGCCAACGGGTGTCGGCGTTGAATC
GACTGTGCTCGATTGCAGCGGAGAGGTGCCGACGATTTTGCGCCCGGGCGGGGTGACGAAAGAGGCGCTCAGTGAAGTGA
TCGGCCGCGTTGAAGAGGCTGCCGGAGATGAACAGACAGCGCCGAAAGCGCCAGGAATGAAATATACGCATTATGCGCCG
AAAGCACCGCTTTGGATCGCCGCTGGCCCACCGTCGTTTTTGCAGCGGCTTGTTGATGAAAGCCGGGCGGAAGGAAAAAC
TGTCGGCGTGCTGACGACTGAAGAAAACAAAAACCGTTATGTCGCCGATGTCGTGTTGGCATGTGGAGCGCGTCGCGATT
TGGAAACGGTGGCCCAACGCCTGTACGATGTGCTGCGTCAGTTTGATGAGACAGGCGTTAACCTCATTTACAGCGAGGCG
TTTCCGGAGGAGGGGATCGGCGCTGCGATCATGAATCGGCTGCGTAAAGCGGCCGGTGGGCGCGTCATTAGCGAATAG

Upstream 100 bases:

>100_bases
TTATTCACAATTTGTGTATAAATGTGGGTAACCGACGAGAGCTAGTTCGGTACTTCTGAGCAAATCCGCCATCTCCAAGG
CGATAGAGAAGGTGAAACGA

Downstream 100 bases:

>100_bases
CGAAACAAAAGCGGAACGCAGCCCCCCAAAAAAGTGAAGGAGCTAACTGTATAGAGTGACGAGTCCGTTCGATGTGAAAG
ATAAGCGAGGGTGTCTCATT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKTHVWVVDNIVDKQQIYPQIQEAAEWLRTGEVIAFPTETVYGLGADAANTTAVEKIFAAKGRPSDNPLIVHVASLAQVE
SIAASIPPVAKTLMERFWPGPLTLVLPKRDGAVSERVTAGLSTVAVRMPDHPLALALIEASGLALAAPSANRSGRPSPTT
AAHVLADLNGRIAGVIDGGPTGVGVESTVLDCSGEVPTILRPGGVTKEALSEVIGRVEEAAGDEQTAPKAPGMKYTHYAP
KAPLWIAAGPPSFLQRLVDESRAEGKTVGVLTTEENKNRYVADVVLACGARRDLETVAQRLYDVLRQFDETGVNLIYSEA
FPEEGIGAAIMNRLRKAAGGRVISE

Sequences:

>Translated_345_residues
MKTHVWVVDNIVDKQQIYPQIQEAAEWLRTGEVIAFPTETVYGLGADAANTTAVEKIFAAKGRPSDNPLIVHVASLAQVE
SIAASIPPVAKTLMERFWPGPLTLVLPKRDGAVSERVTAGLSTVAVRMPDHPLALALIEASGLALAAPSANRSGRPSPTT
AAHVLADLNGRIAGVIDGGPTGVGVESTVLDCSGEVPTILRPGGVTKEALSEVIGRVEEAAGDEQTAPKAPGMKYTHYAP
KAPLWIAAGPPSFLQRLVDESRAEGKTVGVLTTEENKNRYVADVVLACGARRDLETVAQRLYDVLRQFDETGVNLIYSEA
FPEEGIGAAIMNRLRKAAGGRVISE
>Mature_345_residues
MKTHVWVVDNIVDKQQIYPQIQEAAEWLRTGEVIAFPTETVYGLGADAANTTAVEKIFAAKGRPSDNPLIVHVASLAQVE
SIAASIPPVAKTLMERFWPGPLTLVLPKRDGAVSERVTAGLSTVAVRMPDHPLALALIEASGLALAAPSANRSGRPSPTT
AAHVLADLNGRIAGVIDGGPTGVGVESTVLDCSGEVPTILRPGGVTKEALSEVIGRVEEAAGDEQTAPKAPGMKYTHYAP
KAPLWIAAGPPSFLQRLVDESRAEGKTVGVLTTEENKNRYVADVVLACGARRDLETVAQRLYDVLRQFDETGVNLIYSEA
FPEEGIGAAIMNRLRKAAGGRVISE

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=192, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI2367210, Length=151, Percent_Identity=37.0860927152318, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081864, Length=184, Percent_Identity=27.1739130434783, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=202, Percent_Identity=29.2079207920792, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=371, Percent_Identity=39.3530997304582, Blast_Score=218, Evalue=8e-58,
Organism=Drosophila melanogaster, GI78707274, Length=176, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 36523; Mature: 36523

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHVWVVDNIVDKQQIYPQIQEAAEWLRTGEVIAFPTETVYGLGADAANTTAVEKIFAA
CCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCHHHHHHHHHHH
KGRPSDNPLIVHVASLAQVESIAASIPPVAKTLMERFWPGPLTLVLPKRDGAVSERVTAG
CCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHC
LSTVAVRMPDHPLALALIEASGLALAAPSANRSGRPSPTTAAHVLADLNGRIAGVIDGGP
HHEEEEECCCCCEEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCC
TGVGVESTVLDCSGEVPTILRPGGVTKEALSEVIGRVEEAAGDEQTAPKAPGMKYTHYAP
CCCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
KAPLWIAAGPPSFLQRLVDESRAEGKTVGVLTTEENKNRYVADVVLACGARRDLETVAQR
CCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHH
LYDVLRQFDETGVNLIYSEAFPEEGIGAAIMNRLRKAAGGRVISE
HHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTHVWVVDNIVDKQQIYPQIQEAAEWLRTGEVIAFPTETVYGLGADAANTTAVEKIFAA
CCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCHHHHHHHHHHH
KGRPSDNPLIVHVASLAQVESIAASIPPVAKTLMERFWPGPLTLVLPKRDGAVSERVTAG
CCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHC
LSTVAVRMPDHPLALALIEASGLALAAPSANRSGRPSPTTAAHVLADLNGRIAGVIDGGP
HHEEEEECCCCCEEEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCC
TGVGVESTVLDCSGEVPTILRPGGVTKEALSEVIGRVEEAAGDEQTAPKAPGMKYTHYAP
CCCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
KAPLWIAAGPPSFLQRLVDESRAEGKTVGVLTTEENKNRYVADVVLACGARRDLETVAQR
CCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHH
LYDVLRQFDETGVNLIYSEAFPEEGIGAAIMNRLRKAAGGRVISE
HHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]