Click here to switch to the map view.

The map label for this gene is nuoB [H]

Identifier: 138896932

GI number: 138896932

Start: 3411192

End: 3411704

Strand: Reverse

Name: nuoB [H]

Synonym: GTNG_3301

Alternate gene names: 138896932

Gene position: 3411704-3411192 (Counterclockwise)

Preceding gene: 138896933

Following gene: 138896931

Centisome position: 96.1

GC content: 50.68

Gene sequence:

>513_bases
ATGGATGTAAAATGGGATAGTATGACCTTCGATGAAATGGAAGAAGTAAAGCGCAACGTGTTTTTTACGACGCTGGAGCA
GTTAAAAGGATGGGCGCGAAGCAACTCGCTCTGGCCGCTGACGTTCGGTCTTGCCTGTTGTGCGATTGAGATGATGGCAG
TCGGTGGCGCCCATTATGACCTTGATCGGTTTGGTTCATTTTTCCGCGCCTCGCCGCGGCAATCAGATGTCATGATCGTT
TCCGGAACCGTGACGAAAAAAATGGCACCGCTTTTGCGTCGGTTGTATGATCAAATGCCGGAGCCAAAATGGGTGATCGC
CATGGGGTCGTGTGCGACGGCGGGAGGACCGTACGTCAAATCGTACAGCGTCGTGAAAGGGGTTGACCAAATTGTCCCAG
TCGACGTGTACATACCTGGCTGTCCGCCGAACCCTGCGGCACTGATTTATGGCATTCATAAATTAAAAGAAAAAATCCGT
TTGGAAGCCAAAACGGGGAAGAAGGTGTTGTAA

Upstream 100 bases:

>100_bases
TCTATGATCAACTCGGCCTATTTGCTTTAGTGGAGATGATCATTTTCATCGTTTTGCTTGCCATTGGCCTCATTTATGCT
TGGAAAAAGAAGGTGTTACG

Downstream 100 bases:

>100_bases
CCGATGGATGAGGAAAAAGATTTGGCCCAGCGCAAAAAAGAAGCAGCCGAGCGGGCGAGACAGCTAGCGCGCGAACGGCT
GGCCGCCAAGCAAGCAGCCG

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B; NDH-1 subunit B [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MDVKWDSMTFDEMEEVKRNVFFTTLEQLKGWARSNSLWPLTFGLACCAIEMMAVGGAHYDLDRFGSFFRASPRQSDVMIV
SGTVTKKMAPLLRRLYDQMPEPKWVIAMGSCATAGGPYVKSYSVVKGVDQIVPVDVYIPGCPPNPAALIYGIHKLKEKIR
LEAKTGKKVL

Sequences:

>Translated_170_residues
MDVKWDSMTFDEMEEVKRNVFFTTLEQLKGWARSNSLWPLTFGLACCAIEMMAVGGAHYDLDRFGSFFRASPRQSDVMIV
SGTVTKKMAPLLRRLYDQMPEPKWVIAMGSCATAGGPYVKSYSVVKGVDQIVPVDVYIPGCPPNPAALIYGIHKLKEKIR
LEAKTGKKVL
>Mature_170_residues
MDVKWDSMTFDEMEEVKRNVFFTTLEQLKGWARSNSLWPLTFGLACCAIEMMAVGGAHYDLDRFGSFFRASPRQSDVMIV
SGTVTKKMAPLLRRLYDQMPEPKWVIAMGSCATAGGPYVKSYSVVKGVDQIVPVDVYIPGCPPNPAALIYGIHKLKEKIR
LEAKTGKKVL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=140, Percent_Identity=65.7142857142857, Blast_Score=206, Evalue=9e-54,
Organism=Escherichia coli, GI1788624, Length=152, Percent_Identity=53.9473684210526, Blast_Score=176, Evalue=6e-46,
Organism=Escherichia coli, GI1789074, Length=109, Percent_Identity=44.0366972477064, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788834, Length=146, Percent_Identity=36.986301369863, Blast_Score=96, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17509685, Length=136, Percent_Identity=59.5588235294118, Blast_Score=190, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24651058, Length=157, Percent_Identity=57.3248407643312, Blast_Score=202, Evalue=8e-53,
Organism=Drosophila melanogaster, GI18859983, Length=139, Percent_Identity=61.1510791366906, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24642371, Length=139, Percent_Identity=61.1510791366906, Blast_Score=202, Evalue=1e-52,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18984; Mature: 18984

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKWDSMTFDEMEEVKRNVFFTTLEQLKGWARSNSLWPLTFGLACCAIEMMAVGGAHYD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
LDRFGSFFRASPRQSDVMIVSGTVTKKMAPLLRRLYDQMPEPKWVIAMGSCATAGGPYVK
HHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
SYSVVKGVDQIVPVDVYIPGCPPNPAALIYGIHKLKEKIRLEAKTGKKVL
HHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDVKWDSMTFDEMEEVKRNVFFTTLEQLKGWARSNSLWPLTFGLACCAIEMMAVGGAHYD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
LDRFGSFFRASPRQSDVMIVSGTVTKKMAPLLRRLYDQMPEPKWVIAMGSCATAGGPYVK
HHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
SYSVVKGVDQIVPVDVYIPGCPPNPAALIYGIHKLKEKIRLEAKTGKKVL
HHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA