Click here to switch to the map view.

The map label for this gene is hrsA [H]

Identifier: 138896854

GI number: 138896854

Start: 3325601

End: 3327577

Strand: Reverse

Name: hrsA [H]

Synonym: GTNG_3217

Alternate gene names: 138896854

Gene position: 3327577-3325601 (Counterclockwise)

Preceding gene: 138896856

Following gene: 138896853

Centisome position: 93.73

GC content: 49.11

Gene sequence:

>1977_bases
ATGATATCGGGGGGACATACGTTGGAATTAACACAAATGACGAGTGAACGGCTCATCTTATTTGATGTCGGTCTCTCGAC
GAAAGAAGCAGTGATTCGCGCTCTTGTCGATGTTCTTTTTGAAAACGGTGTCTTATCTTCGAAAGAGGCGTTCCTTCAGG
CCGTCATGGAAAGGGAGGCAATTTCTCCAACCGGACTGGAAAAAGGGCTGGCGATTCCGCACGGAAAATCAAAAGCGGTC
AATCGAGCGGCCTTTGCCATTGCGCGCTTATCTTCCCCTATTAAGGATTGGGAAAGCATTGATCCTCATAATGAAGTACA
ACTTGTGTTCTTGCTTGCGATTCCGGAAGCAGAGGCGGGGACGACGCACTTAAATGTATTATCGGAATTAAGCTTGCGTT
TGATGGATGAGGGTTACCTGCGGCGCTTGATGGAGGCCAAAAGCGCTGAGGAATTGCTTCTGGCGCTAGATGAGACAGGG
ACAAGCGGGGGAGACCAAAATGTCACGTATCAAAAAACAGTTTTGGCCATTACAGCCTGTGCTACTGGGATTGCGCATAC
GTATATGGCAGCCGAGGCGTTGGAGAAAGCTGGGCGTGAGCTCGGAGTCCGTGTATTGACAGAAAAGCAAGGAGCTAACG
GAATTCAAGACGAGCTGACGGCAGATGTCATTGCACAAGCCGATGGGGTCATTTTTGCCACGGATATTGCGCCGAAACGC
AAGGAGCGTTTCGCTGGGAAGCCGTACGTGCAAACGAGGGTAGCGGAACCGTTAAAGCATGCAAAACAGATCATCCATAA
AGTGCTTCACCAGCCGGATGGGATTGTCACCGCTTCTGAGGAGGAAACGATGCAAACAGGCAATGGGAAAAAAGCCGGGC
TCTTGTCAGAAATGGCACAGGCGGTGTTAACCGGCATCTCGTATATGCTTCCGGTCATTGTCGCGGCTGGTTTAATGATT
GGCATTGCGAAGCTAGGCTCGATGCCGTTTGGTTTAGTCAACGAAATTAACGATGTGAAGTATGCGACCCATTCGAATGA
GTGGTTTGTCATTTTGCATCATTTAGATAAGTTTGGCGGAATGATCTTCAAGTTCATGTATCCCGTATTCGCTGCGTTCG
TCGCTTATGCGATTGCTGACCGTGTCGGATTGGTATCTGGATTCATTGGCGGTGCGTTTGCGGCTGGATTGCATTACACG
TTTTGGGGAGTGGAAAACGGGATCCCGTCTGGATTTTTTGGTGCCTTGATTCTCGGATTGGCGGCTGGATATGTTTCTCG
ATTCCTCAATAACCATATTCGGTTAAATAAAAATTTCCAAGCAGTGAAGCCGATGCTGATCATTCCGGCCATCAGTGTGT
TGTCTGTTTTCTTCCTGAACTTTTATATTGTCGATCCTGTGTTTGGTGGGTTAAACGCGTGGCTGCGCCAGCTCATTGAG
TCCGCCCAAGACTCAGGTGAGCTCACTCTGTCCGCCATCATTGCAGCGGCGACGGCATTTGATTTAGGCGGACCGATTAA
TAAAGCAGCTGGGGCGATTGCCATTGGTTTGGCGGCAGATCAAATTTTCCCTCTTACGCCGCGGGTGTTGGCGATTGTGA
TCCCGCCGATCGGCTTAGGATTGGCGACGGTTCTTGATAAATATATCGTCGGCCGCCGTGTGTTCGATGAGAATTTGCGC
ATTGCTGGGAACACGGCATTAGTTCTTGGATTTATCGCGATTAGTGAGGGCGCGATTCCGTTTATGCTTCGGAACCCGCT
CATTACGATTCCAGTCAATATTGTCGGTTCGATTTTAGGAGCATGTACAGCCGTCTATTTAGGTGCGGTTCAATGGTTGC
CGCTTCCGGCGTTTTGGGGCTGGCCGTTTGTTGAGAATTTATGGGCTTATTTGACGGGATTGGCTGTAGGGGCATTGTTT
ATCGCTCTCGTCAATATCTTTATCCGATTGGCGTTATTGAAAAGAACAGGGCAATAA

Upstream 100 bases:

>100_bases
GTCAGTTTTGAGGAGAAAGAAGTATAATTGTTCGTCGGATGTACAACTATGAAGGAGAACAGTATGATAAAACAAAATTG
AAAGCGGTTTATGATTATGG

Downstream 100 bases:

>100_bases
AACAAGGTTGACAACAGCATAAGGTTATGGGGTGACATGCCCATAGCCTTATGCTTTTTCATCCTCTTATTGGAGAAGTG
GTAGATCAAGAAAACAGTTG

Product: phosphotransferase system, fructose-specific IIC component

Products: NA

Alternate protein names: Putative PTS system EIIABC component; Phosphotransferase enzyme IIA component; PTS system EIIA component; Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MISGGHTLELTQMTSERLILFDVGLSTKEAVIRALVDVLFENGVLSSKEAFLQAVMEREAISPTGLEKGLAIPHGKSKAV
NRAAFAIARLSSPIKDWESIDPHNEVQLVFLLAIPEAEAGTTHLNVLSELSLRLMDEGYLRRLMEAKSAEELLLALDETG
TSGGDQNVTYQKTVLAITACATGIAHTYMAAEALEKAGRELGVRVLTEKQGANGIQDELTADVIAQADGVIFATDIAPKR
KERFAGKPYVQTRVAEPLKHAKQIIHKVLHQPDGIVTASEEETMQTGNGKKAGLLSEMAQAVLTGISYMLPVIVAAGLMI
GIAKLGSMPFGLVNEINDVKYATHSNEWFVILHHLDKFGGMIFKFMYPVFAAFVAYAIADRVGLVSGFIGGAFAAGLHYT
FWGVENGIPSGFFGALILGLAAGYVSRFLNNHIRLNKNFQAVKPMLIIPAISVLSVFFLNFYIVDPVFGGLNAWLRQLIE
SAQDSGELTLSAIIAAATAFDLGGPINKAAGAIAIGLAADQIFPLTPRVLAIVIPPIGLGLATVLDKYIVGRRVFDENLR
IAGNTALVLGFIAISEGAIPFMLRNPLITIPVNIVGSILGACTAVYLGAVQWLPLPAFWGWPFVENLWAYLTGLAVGALF
IALVNIFIRLALLKRTGQ

Sequences:

>Translated_658_residues
MISGGHTLELTQMTSERLILFDVGLSTKEAVIRALVDVLFENGVLSSKEAFLQAVMEREAISPTGLEKGLAIPHGKSKAV
NRAAFAIARLSSPIKDWESIDPHNEVQLVFLLAIPEAEAGTTHLNVLSELSLRLMDEGYLRRLMEAKSAEELLLALDETG
TSGGDQNVTYQKTVLAITACATGIAHTYMAAEALEKAGRELGVRVLTEKQGANGIQDELTADVIAQADGVIFATDIAPKR
KERFAGKPYVQTRVAEPLKHAKQIIHKVLHQPDGIVTASEEETMQTGNGKKAGLLSEMAQAVLTGISYMLPVIVAAGLMI
GIAKLGSMPFGLVNEINDVKYATHSNEWFVILHHLDKFGGMIFKFMYPVFAAFVAYAIADRVGLVSGFIGGAFAAGLHYT
FWGVENGIPSGFFGALILGLAAGYVSRFLNNHIRLNKNFQAVKPMLIIPAISVLSVFFLNFYIVDPVFGGLNAWLRQLIE
SAQDSGELTLSAIIAAATAFDLGGPINKAAGAIAIGLAADQIFPLTPRVLAIVIPPIGLGLATVLDKYIVGRRVFDENLR
IAGNTALVLGFIAISEGAIPFMLRNPLITIPVNIVGSILGACTAVYLGAVQWLPLPAFWGWPFVENLWAYLTGLAVGALF
IALVNIFIRLALLKRTGQ
>Mature_658_residues
MISGGHTLELTQMTSERLILFDVGLSTKEAVIRALVDVLFENGVLSSKEAFLQAVMEREAISPTGLEKGLAIPHGKSKAV
NRAAFAIARLSSPIKDWESIDPHNEVQLVFLLAIPEAEAGTTHLNVLSELSLRLMDEGYLRRLMEAKSAEELLLALDETG
TSGGDQNVTYQKTVLAITACATGIAHTYMAAEALEKAGRELGVRVLTEKQGANGIQDELTADVIAQADGVIFATDIAPKR
KERFAGKPYVQTRVAEPLKHAKQIIHKVLHQPDGIVTASEEETMQTGNGKKAGLLSEMAQAVLTGISYMLPVIVAAGLMI
GIAKLGSMPFGLVNEINDVKYATHSNEWFVILHHLDKFGGMIFKFMYPVFAAFVAYAIADRVGLVSGFIGGAFAAGLHYT
FWGVENGIPSGFFGALILGLAAGYVSRFLNNHIRLNKNFQAVKPMLIIPAISVLSVFFLNFYIVDPVFGGLNAWLRQLIE
SAQDSGELTLSAIIAAATAFDLGGPINKAAGAIAIGLAADQIFPLTPRVLAIVIPPIGLGLATVLDKYIVGRRVFDENLR
IAGNTALVLGFIAISEGAIPFMLRNPLITIPVNIVGSILGACTAVYLGAVQWLPLPAFWGWPFVENLWAYLTGLAVGALF
IALVNIFIRLALLKRTGQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=596, Percent_Identity=38.9261744966443, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1788729, Length=383, Percent_Identity=38.3812010443864, Blast_Score=276, Evalue=3e-75,
Organism=Escherichia coli, GI1788492, Length=448, Percent_Identity=36.6071428571429, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87082348, Length=436, Percent_Identity=31.4220183486239, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1790386, Length=347, Percent_Identity=31.700288184438, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1790387, Length=95, Percent_Identity=48.4210526315789, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788730, Length=97, Percent_Identity=41.2371134020619, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788726, Length=139, Percent_Identity=34.5323741007194, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1789597, Length=160, Percent_Identity=31.25, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994992, Length=138, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790390, Length=102, Percent_Identity=39.2156862745098, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 70653; Mature: 70653

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGGHTLELTQMTSERLILFDVGLSTKEAVIRALVDVLFENGVLSSKEAFLQAVMEREA
CCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
ISPTGLEKGLAIPHGKSKAVNRAAFAIARLSSPIKDWESIDPHNEVQLVFLLAIPEAEAG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEEEEECCCCCC
TTHLNVLSELSLRLMDEGYLRRLMEAKSAEELLLALDETGTSGGDQNVTYQKTVLAITAC
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ATGIAHTYMAAEALEKAGRELGVRVLTEKQGANGIQDELTADVIAQADGVIFATDIAPKR
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHH
KERFAGKPYVQTRVAEPLKHAKQIIHKVLHQPDGIVTASEEETMQTGNGKKAGLLSEMAQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHCCCCCCHHHHHHHHH
AVLTGISYMLPVIVAAGLMIGIAKLGSMPFGLVNEINDVKYATHSNEWFVILHHLDKFGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCEEEECCCCEEEEHHHHHHHHH
MIFKFMYPVFAAFVAYAIADRVGLVSGFIGGAFAAGLHYTFWGVENGIPSGFFGALILGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHH
AAGYVSRFLNNHIRLNKNFQAVKPMLIIPAISVLSVFFLNFYIVDPVFGGLNAWLRQLIE
HHHHHHHHHCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SAQDSGELTLSAIIAAATAFDLGGPINKAAGAIAIGLAADQIFPLTPRVLAIVIPPIGLG
HCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEHHCCCCCCCCCEEEEEECCCCCH
LATVLDKYIVGRRVFDENLRIAGNTALVLGFIAISEGAIPFMLRNPLITIPVNIVGSILG
HHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCEEECCCEEEECHHHHHHHHH
ACTAVYLGAVQWLPLPAFWGWPFVENLWAYLTGLAVGALFIALVNIFIRLALLKRTGQ
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISGGHTLELTQMTSERLILFDVGLSTKEAVIRALVDVLFENGVLSSKEAFLQAVMEREA
CCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
ISPTGLEKGLAIPHGKSKAVNRAAFAIARLSSPIKDWESIDPHNEVQLVFLLAIPEAEAG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEEEEECCCCCC
TTHLNVLSELSLRLMDEGYLRRLMEAKSAEELLLALDETGTSGGDQNVTYQKTVLAITAC
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ATGIAHTYMAAEALEKAGRELGVRVLTEKQGANGIQDELTADVIAQADGVIFATDIAPKR
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHH
KERFAGKPYVQTRVAEPLKHAKQIIHKVLHQPDGIVTASEEETMQTGNGKKAGLLSEMAQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHCCCCCCHHHHHHHHH
AVLTGISYMLPVIVAAGLMIGIAKLGSMPFGLVNEINDVKYATHSNEWFVILHHLDKFGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCEEEECCCCEEEEHHHHHHHHH
MIFKFMYPVFAAFVAYAIADRVGLVSGFIGGAFAAGLHYTFWGVENGIPSGFFGALILGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHH
AAGYVSRFLNNHIRLNKNFQAVKPMLIIPAISVLSVFFLNFYIVDPVFGGLNAWLRQLIE
HHHHHHHHHCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SAQDSGELTLSAIIAAATAFDLGGPINKAAGAIAIGLAADQIFPLTPRVLAIVIPPIGLG
HCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEHHCCCCCCCCCEEEEEECCCCCH
LATVLDKYIVGRRVFDENLRIAGNTALVLGFIAISEGAIPFMLRNPLITIPVNIVGSILG
HHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCEEECCCEEEECHHHHHHHHH
ACTAVYLGAVQWLPLPAFWGWPFVENLWAYLTGLAVGALFIALVNIFIRLALLKRTGQ
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9063979; 9278503; 8905232 [H]