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The map label for this gene is amaA [H]

Identifier: 138896822

GI number: 138896822

Start: 3286874

End: 3288058

Strand: Reverse

Name: amaA [H]

Synonym: GTNG_3185

Alternate gene names: 138896822

Gene position: 3288058-3286874 (Counterclockwise)

Preceding gene: 138896823

Following gene: 138896821

Centisome position: 92.61

GC content: 54.51

Gene sequence:

>1185_bases
ATGACAAGGGAAGAAATTAAACGACTCGTTGATGAAGTGAAAGCGGACGTCATTGCCTGGCGCCGCCATCTACATGCTCA
TCCTGAATTGTCGTTCCAAGAAGAGAAAACCGCGCAGTTTGTCTACGAGACGCTGCAATCGTTCGGTCATCTTGAGCTTT
CAAGGCCGACGAAAACAAGCGTGATGGCGCGGCTTGTCGGCAAGCAGCCGGGACGGGTCGTCGCCATTCGCGCTGATATG
GACGCGCTGCCGATTCAAGAGGAAAATACGTTTGAGTTTGCCTCAAAAAACCCTGGCGTCATGCATGCGTGCGGTCATGA
CGGCCATACGGCGATGCTTCTTGGCGCGGCAAAAATTTTTTCCCAGTTGCGCGATACGATCCGTGGTGAGATTCGCTTTT
TGTTCCAACACGCGGAAGAGCTGTTCCCAGGAGGAGCGGAAGAGATGGTGCAAGCTGGCGTCATGGACGGGGTCGATGTC
GTCATCGGCACTCACCTTTGGTCGCCGCTTGATCTTGGAAAAGTCGGCATTGTGTACGGACCGATGATGGCCGCGCCGGA
CCGCTTTTTCATTCGCATTATCGGCAAGGGTGGCCATGGAGCCATGCCGCACCAAACGATCGATGCTATCGCGATCGGGG
CGCAAGTCGTGACGAATTTGCAACATATCGTCTCGCGCTACGTTGACCCGGTCGAGCCGCTCGTTTTGTCCGTGACGCAA
TTTGTCGCCGGCACGGCGCATAACGTCCTGCCTGGAGAGGTCGAAATCCAAGGGACGGTGCGCACGTTTGATGACACGTT
GCGTCACACGGTGCCGCAATGGATGGAGCGCATTGTGAAAGGCATTACCGAAGCGCATGGCGCCTCGTACGAGTTCGAAT
TTAACTACGGCTATCGCCCGGTTGTGAACTACGATGAAGTGACGCGCGTCATTGAAGACACAGCGCGTGAACTGTTTGGG
GAGGAAGCTGTCGCCCGCTTGAAACCGAACATGGGTGGCGAAGATTTCTCCGCCTTCTTGCAAAAAGCGCCAGGCAGCTT
CTTCTACGTCGGCGCTAGAAACGAAGAAAAGGGAATTGTGTATCCGCATCACCATCCGCGCTTTACGATTGACGAAGATG
CGCTCGAAATCGGTGTGCAATTGTTTGTCGGTGCAACGTTGAAATTATTGGCGGAAGCGGAATAA

Upstream 100 bases:

>100_bases
ACATGCCTAGAGTTGAAGTTGACCTTGATCAACGTCCGCCAAAGGGACAAAAGCGACGTCAAGGGCGACAGGAACAAAAA
AGAACAGGGGGAGAACTTGG

Downstream 100 bases:

>100_bases
CCGTTTTCGCCTTCGTTCATCCAATGAGGGGAGGGGGGAGAGGATGAAATCGATTCGTTGGCTGATGGTGTTGCCGTTTC
TTGGTATGCTTGGTGGCATC

Product: N-acyl-L-amino acid amidohydrolase

Products: NA

Alternate protein names: L-aminoacylase [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTREEIKRLVDEVKADVIAWRRHLHAHPELSFQEEKTAQFVYETLQSFGHLELSRPTKTSVMARLVGKQPGRVVAIRADM
DALPIQEENTFEFASKNPGVMHACGHDGHTAMLLGAAKIFSQLRDTIRGEIRFLFQHAEELFPGGAEEMVQAGVMDGVDV
VIGTHLWSPLDLGKVGIVYGPMMAAPDRFFIRIIGKGGHGAMPHQTIDAIAIGAQVVTNLQHIVSRYVDPVEPLVLSVTQ
FVAGTAHNVLPGEVEIQGTVRTFDDTLRHTVPQWMERIVKGITEAHGASYEFEFNYGYRPVVNYDEVTRVIEDTARELFG
EEAVARLKPNMGGEDFSAFLQKAPGSFFYVGARNEEKGIVYPHHHPRFTIDEDALEIGVQLFVGATLKLLAEAE

Sequences:

>Translated_394_residues
MTREEIKRLVDEVKADVIAWRRHLHAHPELSFQEEKTAQFVYETLQSFGHLELSRPTKTSVMARLVGKQPGRVVAIRADM
DALPIQEENTFEFASKNPGVMHACGHDGHTAMLLGAAKIFSQLRDTIRGEIRFLFQHAEELFPGGAEEMVQAGVMDGVDV
VIGTHLWSPLDLGKVGIVYGPMMAAPDRFFIRIIGKGGHGAMPHQTIDAIAIGAQVVTNLQHIVSRYVDPVEPLVLSVTQ
FVAGTAHNVLPGEVEIQGTVRTFDDTLRHTVPQWMERIVKGITEAHGASYEFEFNYGYRPVVNYDEVTRVIEDTARELFG
EEAVARLKPNMGGEDFSAFLQKAPGSFFYVGARNEEKGIVYPHHHPRFTIDEDALEIGVQLFVGATLKLLAEAE
>Mature_393_residues
TREEIKRLVDEVKADVIAWRRHLHAHPELSFQEEKTAQFVYETLQSFGHLELSRPTKTSVMARLVGKQPGRVVAIRADMD
ALPIQEENTFEFASKNPGVMHACGHDGHTAMLLGAAKIFSQLRDTIRGEIRFLFQHAEELFPGGAEEMVQAGVMDGVDVV
IGTHLWSPLDLGKVGIVYGPMMAAPDRFFIRIIGKGGHGAMPHQTIDAIAIGAQVVTNLQHIVSRYVDPVEPLVLSVTQF
VAGTAHNVLPGEVEIQGTVRTFDDTLRHTVPQWMERIVKGITEAHGASYEFEFNYGYRPVVNYDEVTRVIEDTARELFGE
EAVARLKPNMGGEDFSAFLQKAPGSFFYVGARNEEKGIVYPHHHPRFTIDEDALEIGVQLFVGATLKLLAEAE

Specific function: Hydrolyzes most efficiently N-acetyl derivatives of aromatic amino acids but is also active on other amino acids. L- stereospecific [H]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=437, Percent_Identity=27.2311212814645, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.14 [H]

Molecular weight: Translated: 43807; Mature: 43675

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREEIKRLVDEVKADVIAWRRHLHAHPELSFQEEKTAQFVYETLQSFGHLELSRPTKTS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHH
VMARLVGKQPGRVVAIRADMDALPIQEENTFEFASKNPGVMHACGHDGHTAMLLGAAKIF
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCEEEECCCCCCHHHHHHHHHHH
SQLRDTIRGEIRFLFQHAEELFPGGAEEMVQAGVMDGVDVVIGTHLWSPLDLGKVGIVYG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHEEC
PMMAAPDRFFIRIIGKGGHGAMPHQTIDAIAIGAQVVTNLQHIVSRYVDPVEPLVLSVTQ
CHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FVAGTAHNVLPGEVEIQGTVRTFDDTLRHTVPQWMERIVKGITEAHGASYEFEFNYGYRP
HHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
VVNYDEVTRVIEDTARELFGEEAVARLKPNMGGEDFSAFLQKAPGSFFYVGARNEEKGIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEE
YPHHHPRFTIDEDALEIGVQLFVGATLKLLAEAE
CCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TREEIKRLVDEVKADVIAWRRHLHAHPELSFQEEKTAQFVYETLQSFGHLELSRPTKTS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHH
VMARLVGKQPGRVVAIRADMDALPIQEENTFEFASKNPGVMHACGHDGHTAMLLGAAKIF
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCEEEECCCCCCHHHHHHHHHHH
SQLRDTIRGEIRFLFQHAEELFPGGAEEMVQAGVMDGVDVVIGTHLWSPLDLGKVGIVYG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHEEC
PMMAAPDRFFIRIIGKGGHGAMPHQTIDAIAIGAQVVTNLQHIVSRYVDPVEPLVLSVTQ
CHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FVAGTAHNVLPGEVEIQGTVRTFDDTLRHTVPQWMERIVKGITEAHGASYEFEFNYGYRP
HHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
VVNYDEVTRVIEDTARELFGEEAVARLKPNMGGEDFSAFLQKAPGSFFYVGARNEEKGIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEE
YPHHHPRFTIDEDALEIGVQLFVGATLKLLAEAE
CCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8285691; 9023955 [H]