Click here to switch to the map view.

The map label for this gene is rbsK [H]

Identifier: 138896811

GI number: 138896811

Start: 3276138

End: 3276995

Strand: Reverse

Name: rbsK [H]

Synonym: GTNG_3174

Alternate gene names: 138896811

Gene position: 3276995-3276138 (Counterclockwise)

Preceding gene: 138896812

Following gene: 138896810

Centisome position: 92.3

GC content: 55.24

Gene sequence:

>858_bases
ATGGACTTAGTAACTGTGGCTGCCCGCTTTCCGAATCAGGGGGAGACGATTTTAGGTAAACAGTTTCTCACCACTCCTGG
CGGCAAGGGGGCGAATCAGGCGGTGGCAGCCGCTCGCCTTGGTGCTAACGTGCGGATGATTGGCGCTGTTGGCGAGGATA
CATTCGGAAAGGAGCTCCTTCGCTCATTGCGAAACGAAGGCATTTCTATCCAGGATGTGAAACCGGTTACACATGAACAT
ACCGGCATTGCTTCGATCACGATTTCTGAACAAGACAATCGCATTATCGTCGTGCCCGGGGCGAACCATGCCTTGACTCC
AGAAGATCTTGACAAGTGCGAGTCGATCATCGCCCAAAGCGATGTTTGCCTATTGCAATTGGAAATTCCGATTCCGGTTG
TCGAACGGGCCGTTTCGTTGGCTCATCGCCATGGTGTGCGTGTCATTGTTAACCCGGCTCCAGCGCAGCCACTGTCGCCG
TCAGTGCTCGAGCAGGTCGATTTTCTAACGCCAAACGAACATGAACGCGCGTTGCTGTTTGCTGGGATAGAAGAGGGCAA
GTTTGTCAATAAACTGATCGTCACCGAAGGGGCCAAAGGGGTGCGCATTTGGCAGGATGGACAGGAACAGCTCATCCCGA
GTTTCCGCGTTCCGGTTGTCGATACGACTGGGGCGGGCGATACGTTTAACGGCGCGCTCGCCGTTGCGCTGGCGGAAGGG
AAGCCGCTCGATGAAGCGTGCCGGTTTGCCAACGCGGCCGCAGCGCTATCGGTCACCAAGCTCGGAGCGCAGGCTGGGAT
GCCGACACGAGAGGATGTGGAATCATTTTTAGCTAAACAGAAAGGGAATCAAGGATGA

Upstream 100 bases:

>100_bases
TTCATTACCAACTTCCGGTTCAATTGATTGTACGGCAATCCACGTCAAGGAGGGAACAAATGTGAACAAGCCTATCATTA
CTGTGATCGGCAGTATCAAT

Downstream 100 bases:

>100_bases
AAAAGAATGGGATCTTGAATAAAGAATTGAACACATTGCTTGCTTCGCTAGGGCATACCGATACGATCGTGATTGCCGAT
TGTGGGCTGCCGATTCCAAA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MDLVTVAARFPNQGETILGKQFLTTPGGKGANQAVAAARLGANVRMIGAVGEDTFGKELLRSLRNEGISIQDVKPVTHEH
TGIASITISEQDNRIIVVPGANHALTPEDLDKCESIIAQSDVCLLQLEIPIPVVERAVSLAHRHGVRVIVNPAPAQPLSP
SVLEQVDFLTPNEHERALLFAGIEEGKFVNKLIVTEGAKGVRIWQDGQEQLIPSFRVPVVDTTGAGDTFNGALAVALAEG
KPLDEACRFANAAAALSVTKLGAQAGMPTREDVESFLAKQKGNQG

Sequences:

>Translated_285_residues
MDLVTVAARFPNQGETILGKQFLTTPGGKGANQAVAAARLGANVRMIGAVGEDTFGKELLRSLRNEGISIQDVKPVTHEH
TGIASITISEQDNRIIVVPGANHALTPEDLDKCESIIAQSDVCLLQLEIPIPVVERAVSLAHRHGVRVIVNPAPAQPLSP
SVLEQVDFLTPNEHERALLFAGIEEGKFVNKLIVTEGAKGVRIWQDGQEQLIPSFRVPVVDTTGAGDTFNGALAVALAEG
KPLDEACRFANAAAALSVTKLGAQAGMPTREDVESFLAKQKGNQG
>Mature_285_residues
MDLVTVAARFPNQGETILGKQFLTTPGGKGANQAVAAARLGANVRMIGAVGEDTFGKELLRSLRNEGISIQDVKPVTHEH
TGIASITISEQDNRIIVVPGANHALTPEDLDKCESIIAQSDVCLLQLEIPIPVVERAVSLAHRHGVRVIVNPAPAQPLSP
SVLEQVDFLTPNEHERALLFAGIEEGKFVNKLIVTEGAKGVRIWQDGQEQLIPSFRVPVVDTTGAGDTFNGALAVALAEG
KPLDEACRFANAAAALSVTKLGAQAGMPTREDVESFLAKQKGNQG

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=292, Percent_Identity=36.986301369863, Blast_Score=163, Evalue=1e-40,
Organism=Escherichia coli, GI1790193, Length=286, Percent_Identity=41.958041958042, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI87082343, Length=289, Percent_Identity=33.2179930795848, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87081971, Length=279, Percent_Identity=28.673835125448, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789432, Length=264, Percent_Identity=29.9242424242424, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788491, Length=256, Percent_Identity=26.5625, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=290, Percent_Identity=39.3103448275862, Blast_Score=167, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6319884, Length=320, Percent_Identity=32.1875, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI20128807, Length=292, Percent_Identity=37.3287671232877, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24583886, Length=299, Percent_Identity=29.4314381270903, Blast_Score=104, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30198; Mature: 30198

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLVTVAARFPNQGETILGKQFLTTPGGKGANQAVAAARLGANVRMIGAVGEDTFGKELL
CCEEEEEECCCCCCCEEECCCEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHH
RSLRNEGISIQDVKPVTHEHTGIASITISEQDNRIIVVPGANHALTPEDLDKCESIIAQS
HHHHHCCCEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
DVCLLQLEIPIPVVERAVSLAHRHGVRVIVNPAPAQPLSPSVLEQVDFLTPNEHERALLF
CEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCEEEE
AGIEEGKFVNKLIVTEGAKGVRIWQDGQEQLIPSFRVPVVDTTGAGDTFNGALAVALAEG
EECCCCCHHEEEEEECCCCCEEEEECCHHHCCCCCCCCEEECCCCCCCCCCEEEEEEECC
KPLDEACRFANAAAALSVTKLGAQAGMPTREDVESFLAKQKGNQG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDLVTVAARFPNQGETILGKQFLTTPGGKGANQAVAAARLGANVRMIGAVGEDTFGKELL
CCEEEEEECCCCCCCEEECCCEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHH
RSLRNEGISIQDVKPVTHEHTGIASITISEQDNRIIVVPGANHALTPEDLDKCESIIAQS
HHHHHCCCEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
DVCLLQLEIPIPVVERAVSLAHRHGVRVIVNPAPAQPLSPSVLEQVDFLTPNEHERALLF
CEEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCEEEE
AGIEEGKFVNKLIVTEGAKGVRIWQDGQEQLIPSFRVPVVDTTGAGDTFNGALAVALAEG
EECCCCCHHEEEEEECCCCCEEEEECCHHHCCCCCCCCEEECCCCCCCCCCEEEEEEECC
KPLDEACRFANAAAALSVTKLGAQAGMPTREDVESFLAKQKGNQG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]