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The map label for this gene is yvoF [H]

Identifier: 138896665

GI number: 138896665

Start: 3124185

End: 3124682

Strand: Reverse

Name: yvoF [H]

Synonym: GTNG_3028

Alternate gene names: 138896665

Gene position: 3124682-3124185 (Counterclockwise)

Preceding gene: 138896666

Following gene: 138896664

Centisome position: 88.01

GC content: 54.42

Gene sequence:

>498_bases
GTGAGACGAACGACGAAATACCCCGTGCAAGGGGCGAACTCACTCTGGCAATTGTACCGCACCGTATCGTTTTGGAAAGT
GCTGAAAAACGTCATCATTATCCAAATTGGGCGCTACACGCCGTTTTTGCCGCTGAAAAACTGGCTGTACCGCACGTTTC
TTGGCATGAAGATTGGCGAACAAACGGCGCTTGCCTTTATGGTTATGCCAGATATTTTGTTTCCGGAAAACATCCGTATC
GGCCGCAATTGTGTCATCGGCTACAACACGACGATTCTCGCCCACGAATATTTGGTGGACGAATACCGCCTTGGCGATGT
CGTGATCGGCGATGAGGTGATGATTGGCGCCAACTCCACCATTTTGCCTGGTGTCGTCATCGGCGACCGCGCCGTCGTCG
CCGCGGGCACTGTCGTCCATAAAGACGTCCCACCCGGGGCGATGGTTGCCGGCTGCCCGATGCGCATCGTTCGGATGAAT
GAACCGCCTTCCGAGTAA

Upstream 100 bases:

>100_bases
AGTATTTGGAACAATATGAACCGGACTTTATGCTGGAAAAAATGAGCGATTTGTTGGCCATTGTCGGCATGAACGAATGA
AAGGAGGAACCGTCCTCCCA

Downstream 100 bases:

>100_bases
CGGGGGCGGTTTTTGATTTATATAAAGAAAAGATTCTGAAAAAATGGTAAAATGAATGAAAAAACTATTTTTATCGTGTT
GGAGGAGATTGACGAAAAAG

Product: acetyltransferase

Products: CoA; aacetyl-beta-D-galactoside [C]

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRRTTKYPVQGANSLWQLYRTVSFWKVLKNVIIIQIGRYTPFLPLKNWLYRTFLGMKIGEQTALAFMVMPDILFPENIRI
GRNCVIGYNTTILAHEYLVDEYRLGDVVIGDEVMIGANSTILPGVVIGDRAVVAAGTVVHKDVPPGAMVAGCPMRIVRMN
EPPSE

Sequences:

>Translated_165_residues
MRRTTKYPVQGANSLWQLYRTVSFWKVLKNVIIIQIGRYTPFLPLKNWLYRTFLGMKIGEQTALAFMVMPDILFPENIRI
GRNCVIGYNTTILAHEYLVDEYRLGDVVIGDEVMIGANSTILPGVVIGDRAVVAAGTVVHKDVPPGAMVAGCPMRIVRMN
EPPSE
>Mature_165_residues
MRRTTKYPVQGANSLWQLYRTVSFWKVLKNVIIIQIGRYTPFLPLKNWLYRTFLGMKIGEQTALAFMVMPDILFPENIRI
GRNCVIGYNTTILAHEYLVDEYRLGDVVIGDEVMIGANSTILPGVVIGDRAVVAAGTVVHKDVPPGAMVAGCPMRIVRMN
EPPSE

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=126, Percent_Identity=33.3333333333333, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: 2.3.1.18 [C]

Molecular weight: Translated: 18481; Mature: 18481

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTTKYPVQGANSLWQLYRTVSFWKVLKNVIIIQIGRYTPFLPLKNWLYRTFLGMKIGE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
QTALAFMVMPDILFPENIRIGRNCVIGYNTTILAHEYLVDEYRLGDVVIGDEVMIGANST
HHEEEEEEECCCCCCCCCEECCEEEEECCCEEEEHHHHHHHCCCCCEEECCEEEECCCCC
ILPGVVIGDRAVVAAGTVVHKDVPPGAMVAGCPMRIVRMNEPPSE
CCCEEEECCCEEEEECEEEECCCCCCCEEECCCEEEEEECCCCCC
>Mature Secondary Structure
MRRTTKYPVQGANSLWQLYRTVSFWKVLKNVIIIQIGRYTPFLPLKNWLYRTFLGMKIGE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
QTALAFMVMPDILFPENIRIGRNCVIGYNTTILAHEYLVDEYRLGDVVIGDEVMIGANST
HHEEEEEEECCCCCCCCCEECCEEEEECCCEEEEHHHHHHHCCCCCEEECCEEEECCCCC
ILPGVVIGDRAVVAAGTVVHKDVPPGAMVAGCPMRIVRMNEPPSE
CCCEEEECCCEEEEECEEEECCCCCCCEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: MgSO4; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 1500 {isopropyl} 1200 {isopropyl} 770 {isopropyl} 360 {isopropyl} 0.18 {acetyl-CoA}} 0.049 {acetyl-CoA}} 0.045 {acetyl-CoA}} 0.04 {acetyl-CoA}} [C]

Substrates: Acetyl-CoA; a beta-D-galactoside [C]

Specific reaction: Acetyl-CoA + a beta-D-galactoside = CoA + aacetyl-beta-D-galactoside [C]

General reaction: Acyl group transfer [C]

Inhibitor: 1, 10-Phenanthroline; Acetyl-CoA; Co2+; CoA; Cu2+; MgSO4; Mn2+; p-Chloromercuribenzoate; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]