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The map label for this gene is trxB [H]

Identifier: 138896654

GI number: 138896654

Start: 3114038

End: 3114994

Strand: Reverse

Name: trxB [H]

Synonym: GTNG_3017

Alternate gene names: 138896654

Gene position: 3114994-3114038 (Counterclockwise)

Preceding gene: 138896655

Following gene: 138896653

Centisome position: 87.74

GC content: 50.57

Gene sequence:

>957_bases
GTGGCAGACGAAAAAATTTATGACGTCATTATTGCTGGAGCCGGGCCGGCAGGGCTAACGGCGGCTGTGTATACATCACG
TGCCAATTTGTCAACGCTGATGATCGAACGCGGCGTCCCGGGCGGGCAAATGGTCAATACGGAAGAAGTCGAGAACTATC
CTGGATTTGAGACGATTTTAGGACCGGAATTGGCCACAAAAATGTTTGAACATGCGAAAAAATTTGGTGCGGAATACGCC
TACGGTGATGTGAAAGAAATCATTGACGGTGAGGCGTACAAAACAGTCGTTGTCGGCGACAAAGAATATAAAGCGCGCGC
GGTCATTATCGCCACCGGGGCCGAATATAAAAAGCTCGGCGTGCCAGGTGAAGCAGAGCTTGGCGGCCGCGGCGTCTCGT
ACTGTGCCGTTTGTGATGGGGCATTCTTTAAAGGAAAAGACTTGGTTGTCGTCGGCGGCGGCGACTCAGCGGTTGAAGAA
GGGGTGTATTTAACCCGCTTTGCCAATAAAGTGACGATTGTCCACCGCCGCGACCAACTGCGGGCGCAAAAAATTTTGCA
AGACCGGGCGTTTGCGAATGAAAAAGTGGATTTTATTTGGAATCATACAGTGAAACAAATCAATGAAAAAGATGGAAAAG
TCGGCAGCGTGACGCTCGTTCATACGCAGACTGGGGAAGAGCGTGAATTCCCGTGTGATGGTGTCTTTATTTACATCGGG
ATGGTGCCGCTCTCCAAGCCATTTGCGAACCTCGGCATCACGAACGAAAACGGCTATATTGTGACGAACGAGAAAATGGA
AACAAAAGTACCTGGCATTTTCGCTGCCGGTGATGTGCGGGAAAAAATGCTCCGGCAAATCGTCACGGCAACCGGTGATG
GCAGCATTGCCGCGCAAAGCGCCCAACATTACGTCGAGGAACTGAAAGAAAAATTGAATGCGCAAGGGGCCAACTGA

Upstream 100 bases:

>100_bases
CACCATGGGGACGGCGAATGTGTGAGCAAATCAATAGACGTCATGCTGTGACTTTTATACGATGAAGATGGAGTGATTTT
TGAGCGAAGGAGTGGACGTT

Downstream 100 bases:

>100_bases
GCCGGTAACGAAACCGCAACGAAACCGTAATGGTTATTTAATCCAGATGTAACACGAATGCAACACATATGTCGTATGCT
ATAAGTAAGTAATTGACCCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MADEKIYDVIIAGAGPAGLTAAVYTSRANLSTLMIERGVPGGQMVNTEEVENYPGFETILGPELATKMFEHAKKFGAEYA
YGDVKEIIDGEAYKTVVVGDKEYKARAVIIATGAEYKKLGVPGEAELGGRGVSYCAVCDGAFFKGKDLVVVGGGDSAVEE
GVYLTRFANKVTIVHRRDQLRAQKILQDRAFANEKVDFIWNHTVKQINEKDGKVGSVTLVHTQTGEEREFPCDGVFIYIG
MVPLSKPFANLGITNENGYIVTNEKMETKVPGIFAAGDVREKMLRQIVTATGDGSIAAQSAQHYVEELKEKLNAQGAN

Sequences:

>Translated_318_residues
MADEKIYDVIIAGAGPAGLTAAVYTSRANLSTLMIERGVPGGQMVNTEEVENYPGFETILGPELATKMFEHAKKFGAEYA
YGDVKEIIDGEAYKTVVVGDKEYKARAVIIATGAEYKKLGVPGEAELGGRGVSYCAVCDGAFFKGKDLVVVGGGDSAVEE
GVYLTRFANKVTIVHRRDQLRAQKILQDRAFANEKVDFIWNHTVKQINEKDGKVGSVTLVHTQTGEEREFPCDGVFIYIG
MVPLSKPFANLGITNENGYIVTNEKMETKVPGIFAAGDVREKMLRQIVTATGDGSIAAQSAQHYVEELKEKLNAQGAN
>Mature_317_residues
ADEKIYDVIIAGAGPAGLTAAVYTSRANLSTLMIERGVPGGQMVNTEEVENYPGFETILGPELATKMFEHAKKFGAEYAY
GDVKEIIDGEAYKTVVVGDKEYKARAVIIATGAEYKKLGVPGEAELGGRGVSYCAVCDGAFFKGKDLVVVGGGDSAVEEG
VYLTRFANKVTIVHRRDQLRAQKILQDRAFANEKVDFIWNHTVKQINEKDGKVGSVTLVHTQTGEEREFPCDGVFIYIGM
VPLSKPFANLGITNENGYIVTNEKMETKVPGIFAAGDVREKMLRQIVTATGDGSIAAQSAQHYVEELKEKLNAQGAN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=327, Percent_Identity=25.0764525993884, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI226437568, Length=327, Percent_Identity=25.0764525993884, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI65787454, Length=327, Percent_Identity=25.0764525993884, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=40.1869158878505, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=33.7704918032787, Blast_Score=157, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=39.6825396825397, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=37.6996805111821, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34442; Mature: 34310

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEKIYDVIIAGAGPAGLTAAVYTSRANLSTLMIERGVPGGQMVNTEEVENYPGFETIL
CCCCEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCEECHHHHCCCCCHHHHC
GPELATKMFEHAKKFGAEYAYGDVKEIIDGEAYKTVVVGDKEYKARAVIIATGAEYKKLG
CHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCHHCCC
VPGEAELGGRGVSYCAVCDGAFFKGKDLVVVGGGDSAVEEGVYLTRFANKVTIVHRRDQL
CCCCCCCCCCCCEEEEEECCCEECCCEEEEECCCCHHHHCCEEEEECCCEEEEEECHHHH
RAQKILQDRAFANEKVDFIWNHTVKQINEKDGKVGSVTLVHTQTGEEREFPCDGVFIYIG
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEE
MVPLSKPFANLGITNENGYIVTNEKMETKVPGIFAAGDVREKMLRQIVTATGDGSIAAQS
EEECCCCHHHCEEECCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHH
AQHYVEELKEKLNAQGAN
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADEKIYDVIIAGAGPAGLTAAVYTSRANLSTLMIERGVPGGQMVNTEEVENYPGFETIL
CCCEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCEECHHHHCCCCCHHHHC
GPELATKMFEHAKKFGAEYAYGDVKEIIDGEAYKTVVVGDKEYKARAVIIATGAEYKKLG
CHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEECCCCCCEEEEEEEECCCHHCCC
VPGEAELGGRGVSYCAVCDGAFFKGKDLVVVGGGDSAVEEGVYLTRFANKVTIVHRRDQL
CCCCCCCCCCCCEEEEEECCCEECCCEEEEECCCCHHHHCCEEEEECCCEEEEEECHHHH
RAQKILQDRAFANEKVDFIWNHTVKQINEKDGKVGSVTLVHTQTGEEREFPCDGVFIYIG
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEE
MVPLSKPFANLGITNENGYIVTNEKMETKVPGIFAAGDVREKMLRQIVTATGDGSIAAQS
EEECCCCHHHCEEECCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHH
AQHYVEELKEKLNAQGAN
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]