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The map label for this gene is hpaD [H]

Identifier: 138896627

GI number: 138896627

Start: 3085862

End: 3086791

Strand: Reverse

Name: hpaD [H]

Synonym: GTNG_2990

Alternate gene names: 138896627

Gene position: 3086791-3085862 (Counterclockwise)

Preceding gene: 138896628

Following gene: 138896626

Centisome position: 86.94

GC content: 55.59

Gene sequence:

>930_bases
ATGGCATACCGCGAGGTGAAAGAGCGGCTGCGCGGCTCGATTGCGCCGGTCGTCACGCCGTTTGATGAAGAAGGAAACGT
TGATTTGACCACGTTGACATCGCTCATTGATTGGCATATAAAAAGCGGCACACACGGCATTTCGGTGACAGGAACATCCG
GGGAACCGAGCTCGCTGACGCTTGACGAGCGAAAACAAGTGATGGAAACAGCGAAAAAGGCGGTCGCCGGGCGCGTGCCG
TTCGTGCCGGGGACAGGCTCGACGAACCATGCGGAAACGATTGAGTTAACCAAATTTGCGCAAGAGATTGGGGCCGATGC
CGCCATGGTCATCGTCCCGTATTACAACCGCCCGTCCCAGCAGGCGCTGTATAAGCATTTTAAGGCGGTGGCTGAGTCGG
TTGACATTCCCATCATCGTCTACAATATCCCAGGGCGTACGGCGGTCAATTTGGAAGTTAAAACGTTGGCGCGGCTCGTC
GAGGACTGCCCGAACATTATCGGGGTGAAGGAGTCCAACAAAGATTTCGAACATGTCAATCGGGTGCTATGGCATTGCGG
GCGCGATTTTCTACTGTTCTCCGGCATCGAGCTGTTGTGCTATCCGATGTTGGCGATCGGCGGCGCCGGTTCGATCAGCG
CAACGGCCAACGTGGTGCCGCAGAAGGTAGCCGAGCTGCATGATGCTTGGTTTGACGGCGACGTCAAGCGGGCGCAAGAC
CTTCACTTTGAACTGATGGAGCTCAATGATGTGCTGTTTATTGAAACGAACCCAGGACCGGTAAAGGCAGCGCTTGGCAT
GTTGGGAAAAATCACCCCGAAGCTTCGCCTGCCGCTTGATTTGCCGAGTGAAGAGCACCAGGAACAAATCCGCCGCACGC
TCGTCAAATATGGGTTGTTGACTGAGGCGGCACAGCAGCCGGCGAAATAA

Upstream 100 bases:

>100_bases
TAACAAAAATCATATATGATTTTATAGTTGATTTGATATATATTATCCTGTATAATGTGATTAAGATTCTGAAAAATCAG
TCCATTAGGAGGCAAGGGGG

Downstream 100 bases:

>100_bases
GCGTTGCCGGCTGTTCCGCCTGAAGGAAGGCGGGCGGCGCGCCCACCGGTCTTGACATGGAGAGGCTGTGACGTTGATTA
CCGCGATGGAAGGGAGAGAG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAYREVKERLRGSIAPVVTPFDEEGNVDLTTLTSLIDWHIKSGTHGISVTGTSGEPSSLTLDERKQVMETAKKAVAGRVP
FVPGTGSTNHAETIELTKFAQEIGADAAMVIVPYYNRPSQQALYKHFKAVAESVDIPIIVYNIPGRTAVNLEVKTLARLV
EDCPNIIGVKESNKDFEHVNRVLWHCGRDFLLFSGIELLCYPMLAIGGAGSISATANVVPQKVAELHDAWFDGDVKRAQD
LHFELMELNDVLFIETNPGPVKAALGMLGKITPKLRLPLDLPSEEHQEQIRRTLVKYGLLTEAAQQPAK

Sequences:

>Translated_309_residues
MAYREVKERLRGSIAPVVTPFDEEGNVDLTTLTSLIDWHIKSGTHGISVTGTSGEPSSLTLDERKQVMETAKKAVAGRVP
FVPGTGSTNHAETIELTKFAQEIGADAAMVIVPYYNRPSQQALYKHFKAVAESVDIPIIVYNIPGRTAVNLEVKTLARLV
EDCPNIIGVKESNKDFEHVNRVLWHCGRDFLLFSGIELLCYPMLAIGGAGSISATANVVPQKVAELHDAWFDGDVKRAQD
LHFELMELNDVLFIETNPGPVKAALGMLGKITPKLRLPLDLPSEEHQEQIRRTLVKYGLLTEAAQQPAK
>Mature_308_residues
AYREVKERLRGSIAPVVTPFDEEGNVDLTTLTSLIDWHIKSGTHGISVTGTSGEPSSLTLDERKQVMETAKKAVAGRVPF
VPGTGSTNHAETIELTKFAQEIGADAAMVIVPYYNRPSQQALYKHFKAVAESVDIPIIVYNIPGRTAVNLEVKTLARLVE
DCPNIIGVKESNKDFEHVNRVLWHCGRDFLLFSGIELLCYPMLAIGGAGSISATANVVPQKVAELHDAWFDGDVKRAQDL
HFELMELNDVLFIETNPGPVKAALGMLGKITPKLRLPLDLPSEEHQEQIRRTLVKYGLLTEAAQQPAK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=301, Percent_Identity=30.2325581395349, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI13540533, Length=305, Percent_Identity=26.8852459016393, Blast_Score=101, Evalue=9e-22,
Organism=Escherichia coli, GI1788823, Length=290, Percent_Identity=40.6896551724138, Blast_Score=217, Evalue=6e-58,
Organism=Escherichia coli, GI1786463, Length=279, Percent_Identity=35.84229390681, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI87082415, Length=298, Percent_Identity=29.8657718120805, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789620, Length=244, Percent_Identity=29.0983606557377, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33962; Mature: 33831

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYREVKERLRGSIAPVVTPFDEEGNVDLTTLTSLIDWHIKSGTHGISVTGTSGEPSSLT
CCHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LDERKQVMETAKKAVAGRVPFVPGTGSTNHAETIELTKFAQEIGADAAMVIVPYYNRPSQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHH
QALYKHFKAVAESVDIPIIVYNIPGRTAVNLEVKTLARLVEDCPNIIGVKESNKDFEHVN
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCEECCCCCCCHHHHH
RVLWHCGRDFLLFSGIELLCYPMLAIGGAGSISATANVVPQKVAELHDAWFDGDVKRAQD
HHHHHCCCHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
LHFELMELNDVLFIETNPGPVKAALGMLGKITPKLRLPLDLPSEEHQEQIRRTLVKYGLL
HHHHEEECCCEEEEECCCCHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHH
TEAAQQPAK
HHHHCCCCC
>Mature Secondary Structure 
AYREVKERLRGSIAPVVTPFDEEGNVDLTTLTSLIDWHIKSGTHGISVTGTSGEPSSLT
CHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCC
LDERKQVMETAKKAVAGRVPFVPGTGSTNHAETIELTKFAQEIGADAAMVIVPYYNRPSQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHH
QALYKHFKAVAESVDIPIIVYNIPGRTAVNLEVKTLARLVEDCPNIIGVKESNKDFEHVN
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCEECCCCCCCHHHHH
RVLWHCGRDFLLFSGIELLCYPMLAIGGAGSISATANVVPQKVAELHDAWFDGDVKRAQD
HHHHHCCCHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
LHFELMELNDVLFIETNPGPVKAALGMLGKITPKLRLPLDLPSEEHQEQIRRTLVKYGLL
HHHHEEECCCEEEEECCCCHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHH
TEAAQQPAK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA