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The map label for this gene is iscU [H]

Identifier: 138896580

GI number: 138896580

Start: 3044193

End: 3044627

Strand: Reverse

Name: iscU [H]

Synonym: GTNG_2943

Alternate gene names: 138896580

Gene position: 3044627-3044193 (Counterclockwise)

Preceding gene: 138896581

Following gene: 138896579

Centisome position: 85.76

GC content: 49.2

Gene sequence:

>435_bases
ATGTCTTCTAATCATCCGTTAGACCAGCTTTACCGCCAAGTCATTATGGATCATTATAAAAACCCGCGCAACCGCGGCGT
GCTTGAGGGGACGAACGTCGATATCAACATGAACAACCCGACGTGCGGCGACCGCATTCATTTGACCATGAAAGTGGAGG
ACGGAAAAATCGCTGACGTCAAATTTGAAGGGGAAGGCTGTTCGATTTCGATGTCGTCAGCGTCGATGATGACGCAGGCC
ATTAAAGGGAAAAACGTCGAAGAAGCGCTTCGGCTCGCTCACATTTTTTCGGACATGATTCAAGGCAAGGAATACGATGA
TTCGCTCGATCTTGGCGACATCGAGGCGCTTCAAGGTGTTTCGAAATTTCCGGCCCGCATTAAATGTGCGACATTGGCGT
GGAAAGCGCTCGAAAAAGGGTTGCATGACCATTAA

Upstream 100 bases:

>100_bases
GTGACCGCAACCGCCCGGGCGAGCTTTTACCTGTACAATACGAAAGAGGAAATCGATACGTTTATCGCTGCATTACAGAA
AGCGAAGGAGTACTTCAGCC

Downstream 100 bases:

>100_bases
GATGAAGGAAGGTGAACCACGATGGCGAAAAAAGCACCAGAAATCGGCGAATATAAGTATGGCTTCGTCGATAAGGACGT
TTCCATCTTCCGCGCCCAGC

Product: IscU protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSSNHPLDQLYRQVIMDHYKNPRNRGVLEGTNVDINMNNPTCGDRIHLTMKVEDGKIADVKFEGEGCSISMSSASMMTQA
IKGKNVEEALRLAHIFSDMIQGKEYDDSLDLGDIEALQGVSKFPARIKCATLAWKALEKGLHDH

Sequences:

>Translated_144_residues
MSSNHPLDQLYRQVIMDHYKNPRNRGVLEGTNVDINMNNPTCGDRIHLTMKVEDGKIADVKFEGEGCSISMSSASMMTQA
IKGKNVEEALRLAHIFSDMIQGKEYDDSLDLGDIEALQGVSKFPARIKCATLAWKALEKGLHDH
>Mature_143_residues
SSNHPLDQLYRQVIMDHYKNPRNRGVLEGTNVDINMNNPTCGDRIHLTMKVEDGKIADVKFEGEGCSISMSSASMMTQAI
KGKNVEEALRLAHIFSDMIQGKEYDDSLDLGDIEALQGVSKFPARIKCATLAWKALEKGLHDH

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=140, Percent_Identity=33.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI24307953, Length=134, Percent_Identity=33.5820895522388, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788878, Length=138, Percent_Identity=29.7101449275362, Blast_Score=71, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17543474, Length=138, Percent_Identity=29.7101449275362, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324800, Length=141, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325122, Length=141, Percent_Identity=30.4964539007092, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355597, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002871
- InterPro:   IPR011341 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 16048; Mature: 15916

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNHPLDQLYRQVIMDHYKNPRNRGVLEGTNVDINMNNPTCGDRIHLTMKVEDGKIADV
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCEEEEE
KFEGEGCSISMSSASMMTQAIKGKNVEEALRLAHIFSDMIQGKEYDDSLDLGDIEALQGV
EECCCCCEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SKFPARIKCATLAWKALEKGLHDH
HHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSNHPLDQLYRQVIMDHYKNPRNRGVLEGTNVDINMNNPTCGDRIHLTMKVEDGKIADV
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCEEEEE
KFEGEGCSISMSSASMMTQAIKGKNVEEALRLAHIFSDMIQGKEYDDSLDLGDIEALQGV
EECCCCCEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
SKFPARIKCATLAWKALEKGLHDH
HHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]