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The map label for this gene is yggV [C]

Identifier: 138896230

GI number: 138896230

Start: 2702619

End: 2703233

Strand: Reverse

Name: yggV [C]

Synonym: GTNG_2593

Alternate gene names: 138896230

Gene position: 2703233-2702619 (Counterclockwise)

Preceding gene: 138896231

Following gene: 138896229

Centisome position: 76.14

GC content: 56.1

Gene sequence:

>615_bases
GTGAAGGAAATTGTCATTGCCACGAAAAACGCAGGCAAGGTGCGCGAGTTTGCCGCCATGTTTGCCAAGCGAGGCATCGA
AGTGAAATCGCTGCTCGATTTTCCGGATGTCCCCGATGTCGAAGAAACAGGAAGCACCTTTGTCGAAAATGCTAAATTAA
AAGCTGAAGCGGTATGCCAACGTTTGCAGCGGCCAGTCATCGCTGATGATTCCGGACTTGCCGTCGATGCGCTCGGGGGC
CGACCGGGGGTTCATTCAGCCCGCTACGCCGGCGAAGACAAAAATGATGCACGCAACATCGCCAAACTGCTTCGTGAGCT
TGACGGAGTGCCGATGGAGAAACGGACCGCCCGCTTTCATTGTGCGTTGGCTGTCGCCATTCCCGGGCAGCCGACTGCCA
TTGTCGAGGCAACGTGTGACGGCTATATCGCCGAAGCGCCGCGCGGGGAGGGGGGTTTTGGATACGACCCTGTCTTTTAT
CTTCCGGAGCGTGGGAAAACGATGGCTGAGCTCACGCCAGAAGAGAAAAATGCCATCAGCCATCGAGCGAAGGCGCTGGA
GAAGTTAAATGAGCAATGGGACGAGATCATGGGCGAAAAGGGGCGGACGGAATGA

Upstream 100 bases:

>100_bases
CCCAACTAGGTATTGAACAGCTCATCACCATTCAGCGCCGTGTATTGGGGGAGCAGGCAGCCCTCATCGGAGAGAAAGTA
GAACAGGAGGGGAAATCAGA

Downstream 100 bases:

>100_bases
ACGTCGTCATTGTCAGTGACAGCCACGGGCTGACTGCCGAACTCGCTCAAATTGTGTCGCGTCATCGCCATGAAGCGGAT
TTGTTCATTCATTGCGGTGA

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKEIVIATKNAGKVREFAAMFAKRGIEVKSLLDFPDVPDVEETGSTFVENAKLKAEAVCQRLQRPVIADDSGLAVDALGG
RPGVHSARYAGEDKNDARNIAKLLRELDGVPMEKRTARFHCALAVAIPGQPTAIVEATCDGYIAEAPRGEGGFGYDPVFY
LPERGKTMAELTPEEKNAISHRAKALEKLNEQWDEIMGEKGRTE

Sequences:

>Translated_204_residues
MKEIVIATKNAGKVREFAAMFAKRGIEVKSLLDFPDVPDVEETGSTFVENAKLKAEAVCQRLQRPVIADDSGLAVDALGG
RPGVHSARYAGEDKNDARNIAKLLRELDGVPMEKRTARFHCALAVAIPGQPTAIVEATCDGYIAEAPRGEGGFGYDPVFY
LPERGKTMAELTPEEKNAISHRAKALEKLNEQWDEIMGEKGRTE
>Mature_204_residues
MKEIVIATKNAGKVREFAAMFAKRGIEVKSLLDFPDVPDVEETGSTFVENAKLKAEAVCQRLQRPVIADDSGLAVDALGG
RPGVHSARYAGEDKNDARNIAKLLRELDGVPMEKRTARFHCALAVAIPGQPTAIVEATCDGYIAEAPRGEGGFGYDPVFY
LPERGKTMAELTPEEKNAISHRAKALEKLNEQWDEIMGEKGRTE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=202, Percent_Identity=30.1980198019802, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI31657144, Length=145, Percent_Identity=32.4137931034483, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=50.7853403141361, Blast_Score=187, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17556833, Length=172, Percent_Identity=32.5581395348837, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19920712, Length=200, Percent_Identity=30.5, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22256; Mature: 22256

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIVIATKNAGKVREFAAMFAKRGIEVKSLLDFPDVPDVEETGSTFVENAKLKAEAVCQ
CCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHCHHHHHCCCCCHHHHHH
RLQRPVIADDSGLAVDALGGRPGVHSARYAGEDKNDARNIAKLLRELDGVPMEKRTARFH
HHCCCCEECCCCCEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHEEE
CALAVAIPGQPTAIVEATCDGYIAEAPRGEGGFGYDPVFYLPERGKTMAELTPEEKNAIS
EEEEEEECCCCCEEEEECCCCEECCCCCCCCCCCCCCEEEECCCCCCHHHCCCHHHHHHH
HRAKALEKLNEQWDEIMGEKGRTE
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKEIVIATKNAGKVREFAAMFAKRGIEVKSLLDFPDVPDVEETGSTFVENAKLKAEAVCQ
CCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHCHHHHHCCCCCHHHHHH
RLQRPVIADDSGLAVDALGGRPGVHSARYAGEDKNDARNIAKLLRELDGVPMEKRTARFH
HHCCCCEECCCCCEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHEEE
CALAVAIPGQPTAIVEATCDGYIAEAPRGEGGFGYDPVFYLPERGKTMAELTPEEKNAIS
EEEEEEECCCCCEEEEECCCCEECCCCCCCCCCCCCCEEEECCCCCCHHHCCCHHHHHHH
HRAKALEKLNEQWDEIMGEKGRTE
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA