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The map label for this gene is ilvE [H]

Identifier: 138896228

GI number: 138896228

Start: 2700931

End: 2701830

Strand: Reverse

Name: ilvE [H]

Synonym: GTNG_2591

Alternate gene names: 138896228

Gene position: 2701830-2700931 (Counterclockwise)

Preceding gene: 138896229

Following gene: 138896227

Centisome position: 76.1

GC content: 47.78

Gene sequence:

>900_bases
ATGGGAGAACAATGGATTTTTTTAAACGGAGAATTTGTAACAAAAGAAAACGCAAAAATATCAGTTTATGATCATGGATT
TTTGTATGGGGACGGCGTGTTTGAAGGTATTCGCGTCTATAGCGGCAACGTATTCCGCCTAGAAGAACATATAGATCGTC
TGTATAACTCAGCTAAGTCCATTATGCTGAACATTCCATACACGAAAGATGAAATGATCAACCACGTGCTCGAAACCGTC
CGTCGCAATGGATATCAAGATGCGTACATCCGCCTTGTCGTTTCGCGCGGGGTTGGCGATTTGGGGCTTGACCCGTATAA
ATGCAAATCACCGCAAGTCGTGATTATCGTTGAGCCGCTGGCGCTCTTCCCGAAACATTTATATGAAACGGGTATCGAAG
TCGTGACAGTGGCAACACGTCGCAACCGCTCTGACGTGTTGAGCCCAAAAGTCAAGTCGCTCAACTATTTGAACAATGTT
CTTGTGAAGATCGAGGCGCATTTGGCCAATGTTAGTGAAGCTCTTATTTTAAACGATCAAGGGTATGTAGCGGAAGGTTC
CGGGGACAACATCTTCATCGTCAAAAACGGCGTCGTTTACACCCCTCCGGGATATGTCGGAGCGCTTGAAGGCATTACGC
GCCAAGCGATTATCGAAATTGCTGAGGAGCTTGGCTATACGGTCAAAGAAGAGCCATTTACCCGCCATGATGTATATGTC
GCTGATGAGGTGTTTTTAACCGGGACGGCGGCTGAAGTCATTTCCGTCATTAAAGTGGACGGCCGGACGATCGGCGATGG
AACACCTGGTCCGCATACGAAGCGGCTTCTTGAAGAATTCCGGCGCCGCGTGATCGCGGAAGGAGTCAAAGTATATCCGA
CCAAAGCCAATGTCGGTTGA

Upstream 100 bases:

>100_bases
GTTTAGGATTATTATAATTTTCAAATAAGAGGAACGACTTAAATTCATCATCAAGCCGTTCAAAGCAACCATTGACTGAT
CAAGGAAGAGGGGAACCGAA

Downstream 100 bases:

>100_bases
GAGACAATGACAACTGCATAGGGAAAAAGCGTTGATGAGGACAAGTAATCAGCGGGGCCAACATCCACAGAGAGCCGGGG
GAGCTGGGAACCGGTGATGT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MGEQWIFLNGEFVTKENAKISVYDHGFLYGDGVFEGIRVYSGNVFRLEEHIDRLYNSAKSIMLNIPYTKDEMINHVLETV
RRNGYQDAYIRLVVSRGVGDLGLDPYKCKSPQVVIIVEPLALFPKHLYETGIEVVTVATRRNRSDVLSPKVKSLNYLNNV
LVKIEAHLANVSEALILNDQGYVAEGSGDNIFIVKNGVVYTPPGYVGALEGITRQAIIEIAEELGYTVKEEPFTRHDVYV
ADEVFLTGTAAEVISVIKVDGRTIGDGTPGPHTKRLLEEFRRRVIAEGVKVYPTKANVG

Sequences:

>Translated_299_residues
MGEQWIFLNGEFVTKENAKISVYDHGFLYGDGVFEGIRVYSGNVFRLEEHIDRLYNSAKSIMLNIPYTKDEMINHVLETV
RRNGYQDAYIRLVVSRGVGDLGLDPYKCKSPQVVIIVEPLALFPKHLYETGIEVVTVATRRNRSDVLSPKVKSLNYLNNV
LVKIEAHLANVSEALILNDQGYVAEGSGDNIFIVKNGVVYTPPGYVGALEGITRQAIIEIAEELGYTVKEEPFTRHDVYV
ADEVFLTGTAAEVISVIKVDGRTIGDGTPGPHTKRLLEEFRRRVIAEGVKVYPTKANVG
>Mature_298_residues
GEQWIFLNGEFVTKENAKISVYDHGFLYGDGVFEGIRVYSGNVFRLEEHIDRLYNSAKSIMLNIPYTKDEMINHVLETVR
RNGYQDAYIRLVVSRGVGDLGLDPYKCKSPQVVIIVEPLALFPKHLYETGIEVVTVATRRNRSDVLSPKVKSLNYLNNVL
VKIEAHLANVSEALILNDQGYVAEGSGDNIFIVKNGVVYTPPGYVGALEGITRQAIIEIAEELGYTVKEEPFTRHDVYVA
DEVFLTGTAAEVISVIKVDGRTIGDGTPGPHTKRLLEEFRRRVIAEGVKVYPTKANVG

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=282, Percent_Identity=39.7163120567376, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1787338, Length=256, Percent_Identity=28.125, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33319; Mature: 33187

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEQWIFLNGEFVTKENAKISVYDHGFLYGDGVFEGIRVYSGNVFRLEEHIDRLYNSAKS
CCCEEEEECCEEEECCCCEEEEEECCEEEECCHHCCEEEECCCEEEHHHHHHHHHHCCCE
IMLNIPYTKDEMINHVLETVRRNGYQDAYIRLVVSRGVGDLGLDPYKCKSPQVVIIVEPL
EEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCH
ALFPKHLYETGIEVVTVATRRNRSDVLSPKVKSLNYLNNVLVKIEAHLANVSEALILNDQ
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEEEEEEHHHCCCCEEEEECCC
GYVAEGSGDNIFIVKNGVVYTPPGYVGALEGITRQAIIEIAEELGYTVKEEPFTRHDVYV
CEEEECCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEE
ADEVFLTGTAAEVISVIKVDGRTIGDGTPGPHTKRLLEEFRRRVIAEGVKVYPTKANVG
ECEEEEECCHHHHHHHHEECCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCC
>Mature Secondary Structure 
GEQWIFLNGEFVTKENAKISVYDHGFLYGDGVFEGIRVYSGNVFRLEEHIDRLYNSAKS
CCEEEEECCEEEECCCCEEEEEECCEEEECCHHCCEEEECCCEEEHHHHHHHHHHCCCE
IMLNIPYTKDEMINHVLETVRRNGYQDAYIRLVVSRGVGDLGLDPYKCKSPQVVIIVEPL
EEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCH
ALFPKHLYETGIEVVTVATRRNRSDVLSPKVKSLNYLNNVLVKIEAHLANVSEALILNDQ
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEEEEEEHHHCCCCEEEEECCC
GYVAEGSGDNIFIVKNGVVYTPPGYVGALEGITRQAIIEIAEELGYTVKEEPFTRHDVYV
CEEEECCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEE
ADEVFLTGTAAEVISVIKVDGRTIGDGTPGPHTKRLLEEFRRRVIAEGVKVYPTKANVG
ECEEEEECCHHHHHHHHEECCEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]