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The map label for this gene is secDF [H]

Identifier: 138896150

GI number: 138896150

Start: 2618674

End: 2620926

Strand: Reverse

Name: secDF [H]

Synonym: GTNG_2513

Alternate gene names: 138896150

Gene position: 2620926-2618674 (Counterclockwise)

Preceding gene: 138896151

Following gene: 138896149

Centisome position: 73.82

GC content: 49.84

Gene sequence:

>2253_bases
ATGGTAAAACAAAGTCGCATCGTCACGTTTTTTTTGCTCGTGCTCCTATTGGCTGGAGTGATCGGACCGACGATTCAAGG
AATTTTACATAATATCAAGCTCGGCCTTGATTTGCAAGGCGGTTTTGAAGTGTTGTATGAGGTGAAGCCGGCGAAAAAAG
GCGATAAAATTGACCAGGAAACGCTCCAAAGCACGGTCAGCGCCTTAAACAAGCGGATTAACGTCCTCGGCGTCAGCGAG
CCGCGCGTCGACATCGAAGGCGAAAACCGTATTCGCGTCCAGCTCGCCGGGGTGAAGGATCAAAACGAGGCACGCGAAAT
TTTGGCCACCCAGGCAAAGTTGACGTTCCGTGACGTCAATGACAACGTGCTCATGGACGGGAGCGATCTTGTCCAAGGCG
GAGCGAAGCTGTCGTTTGATGAGAACGGTCAGCCGAGTGTCGCTATTAAATTGAAAGATGCCGATAAGTTTCGCCAAGTG
ACGGAAAAAGTGTACAACATGGGTCCACCGAACAATATTTTGGTCATTTGGCTTGATTTTGAAGAAGGAGTTGACTCGTA
CCAAAAAGAAGCGGGCAAAGCGGATCCGAAATTTATTTCCGCTGCTTCGGTCAACCAAGTTTTCAATCAGACAGACGTGT
CGATTGTCGGCAACTTTACGGTGAAAGAAGCACAGCAGCTGGCTGATCTGTTAAACGCCGGCGCACTTCCAGTCGAATTG
CATGAAATTTACTCGACGTCTGTTGGCGCCCAATTCGGGAAAAACGCCCTGCAAACAACGATGTTGGCTGGCATCATCGG
TGTTGCTGCCATCTTCTTGTTTATGATTTGGTTTTACCGATTGCCAGGCGTGATTGCCGTCATTACACTGTCGGTGTACA
TTTATTTGATTCTGTTATTGTTTGATTGGATGAACGGCGTCTTGACGTTGCCAGGCATTGCCGCCCTTATTTTAGGGGTC
GGGATGGCGGTCGACGCCAACATTATTACGTATGAGCGAATCAAGGAAGAGCTAAAGCTTGGCAAATCGATGATGTCGGC
GTTTCGCGCCGGCAACCGAGGTTCGTTTGCAACGATTTTTGACGCCAACATTACGACGATCATCGCCGGCGTCGTCCTGT
TCATTTACGGAACAAGCTCGGTCAAAGGGTTCGCGACGATGCTCATTATCAGCATTGTCGCCAGCTTTGTCACTGCTGTC
TACGGCACGCGCCTGTTGCTCGGGCTGCTCGTCTCAAGCCGCTGGCTTGATAAGAAACCGGGTTATTTCGGCGTGAAAAA
ATCGGAAATCTTAAACATTGCCGAAACGACCGATGAGACAGAAGTGCCGACGAAGTTTGACCGTTGGGATTTTATCAAAC
ATAGCAAAAAGTTTTTCCTGTTCTCCATCGCCTTGACGATTGCCGGTGTCATTTCACTTTTTGCCATGGGGCTCAATCTC
GGCATTGATTTCACGAGCGGGACGCGCATTGAGGTGACGAGCAGTCAACCGATTGAAGCCAAGGAGCTAAGCGACTATTT
TGAACAGCTTGGTCACAAGCCGGAGGATGTCGTTTTATCTGGCACGGACGGGAAAACAGGCGTCGTCCGCTTGATCGGAG
TGCTTGACAAGCAGGAAATTGCGAAAATCAAAAGTGAGCTGAAAACGACGTACGGGCATGAACCCAACATCAGCACCGTG
TCGCCCGTTGTCGGCAAGCAGTTAGCGCGAAACGCGCTCATTGCCGTGCTCATTTCGTCGATTGGGATCATTCTTTATGT
GACGATCCGCTTTGAATGGCGGATGGCGTTAGCTGCTATCATCGCCTTATTGCACGATGCGTTTTTCATCATTACTGTGT
TCAGCTTGACGCGGCTTGAGGTTGATTTGACGTTCATCGCCGCCGTGTTGACGATCATTGGTTACTCGATCAATGATACG
ATTGTCACGTTTGACCGCATTCGCGATCTCATGAAAAAACGGAAAGTGAAAACGGTCGACGATTTAAGGCACATCGTCAA
CCGAGCGTTGCAGCAAACGTTCACACGCTCAATCAACACCGTATTGACCGTTTTGTTTACGGTGATTGCCTTACTTCTGT
TTGGCAGCGAGGCGATCCGCAACTTCAACCTTGCCTTGCTCGCCGGCCTGTTGTGCGGCGTCTATTCCTCGCTGTTCATC
GCTGCACAGCTGTGGCTCGTTTGGAAAGGAAATGCGCTCAAAAAAGGCAAAGGGACGAAAAAAATCACGCCGGAAACCGA
GCCGCACCTGTAA

Upstream 100 bases:

>100_bases
GCCGACTGGCGCATAATGGAAGTCGAAACCGATGTGTTCAACGATGGTGCTGTAGAAGCCGCCGGGCGTCAAGATGAATC
GAAGGAGGATTTTACAACGA

Downstream 100 bases:

>100_bases
TGTCCGCACCGGAAAAAGTGCTTGCGCTTTTTCCGGTGCTTTTTCTTTTAACGACGATGCTTGGAACGGAAAATGGATAC
ACTAATGGCCAGATGAAACA

Product: bifunctional preprotein translocase subunit SecD/SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 750; Mature: 750

Protein sequence:

>750_residues
MVKQSRIVTFFLLVLLLAGVIGPTIQGILHNIKLGLDLQGGFEVLYEVKPAKKGDKIDQETLQSTVSALNKRINVLGVSE
PRVDIEGENRIRVQLAGVKDQNEAREILATQAKLTFRDVNDNVLMDGSDLVQGGAKLSFDENGQPSVAIKLKDADKFRQV
TEKVYNMGPPNNILVIWLDFEEGVDSYQKEAGKADPKFISAASVNQVFNQTDVSIVGNFTVKEAQQLADLLNAGALPVEL
HEIYSTSVGAQFGKNALQTTMLAGIIGVAAIFLFMIWFYRLPGVIAVITLSVYIYLILLLFDWMNGVLTLPGIAALILGV
GMAVDANIITYERIKEELKLGKSMMSAFRAGNRGSFATIFDANITTIIAGVVLFIYGTSSVKGFATMLIISIVASFVTAV
YGTRLLLGLLVSSRWLDKKPGYFGVKKSEILNIAETTDETEVPTKFDRWDFIKHSKKFFLFSIALTIAGVISLFAMGLNL
GIDFTSGTRIEVTSSQPIEAKELSDYFEQLGHKPEDVVLSGTDGKTGVVRLIGVLDKQEIAKIKSELKTTYGHEPNISTV
SPVVGKQLARNALIAVLISSIGIILYVTIRFEWRMALAAIIALLHDAFFIITVFSLTRLEVDLTFIAAVLTIIGYSINDT
IVTFDRIRDLMKKRKVKTVDDLRHIVNRALQQTFTRSINTVLTVLFTVIALLLFGSEAIRNFNLALLAGLLCGVYSSLFI
AAQLWLVWKGNALKKGKGTKKITPETEPHL

Sequences:

>Translated_750_residues
MVKQSRIVTFFLLVLLLAGVIGPTIQGILHNIKLGLDLQGGFEVLYEVKPAKKGDKIDQETLQSTVSALNKRINVLGVSE
PRVDIEGENRIRVQLAGVKDQNEAREILATQAKLTFRDVNDNVLMDGSDLVQGGAKLSFDENGQPSVAIKLKDADKFRQV
TEKVYNMGPPNNILVIWLDFEEGVDSYQKEAGKADPKFISAASVNQVFNQTDVSIVGNFTVKEAQQLADLLNAGALPVEL
HEIYSTSVGAQFGKNALQTTMLAGIIGVAAIFLFMIWFYRLPGVIAVITLSVYIYLILLLFDWMNGVLTLPGIAALILGV
GMAVDANIITYERIKEELKLGKSMMSAFRAGNRGSFATIFDANITTIIAGVVLFIYGTSSVKGFATMLIISIVASFVTAV
YGTRLLLGLLVSSRWLDKKPGYFGVKKSEILNIAETTDETEVPTKFDRWDFIKHSKKFFLFSIALTIAGVISLFAMGLNL
GIDFTSGTRIEVTSSQPIEAKELSDYFEQLGHKPEDVVLSGTDGKTGVVRLIGVLDKQEIAKIKSELKTTYGHEPNISTV
SPVVGKQLARNALIAVLISSIGIILYVTIRFEWRMALAAIIALLHDAFFIITVFSLTRLEVDLTFIAAVLTIIGYSINDT
IVTFDRIRDLMKKRKVKTVDDLRHIVNRALQQTFTRSINTVLTVLFTVIALLLFGSEAIRNFNLALLAGLLCGVYSSLFI
AAQLWLVWKGNALKKGKGTKKITPETEPHL
>Mature_750_residues
MVKQSRIVTFFLLVLLLAGVIGPTIQGILHNIKLGLDLQGGFEVLYEVKPAKKGDKIDQETLQSTVSALNKRINVLGVSE
PRVDIEGENRIRVQLAGVKDQNEAREILATQAKLTFRDVNDNVLMDGSDLVQGGAKLSFDENGQPSVAIKLKDADKFRQV
TEKVYNMGPPNNILVIWLDFEEGVDSYQKEAGKADPKFISAASVNQVFNQTDVSIVGNFTVKEAQQLADLLNAGALPVEL
HEIYSTSVGAQFGKNALQTTMLAGIIGVAAIFLFMIWFYRLPGVIAVITLSVYIYLILLLFDWMNGVLTLPGIAALILGV
GMAVDANIITYERIKEELKLGKSMMSAFRAGNRGSFATIFDANITTIIAGVVLFIYGTSSVKGFATMLIISIVASFVTAV
YGTRLLLGLLVSSRWLDKKPGYFGVKKSEILNIAETTDETEVPTKFDRWDFIKHSKKFFLFSIALTIAGVISLFAMGLNL
GIDFTSGTRIEVTSSQPIEAKELSDYFEQLGHKPEDVVLSGTDGKTGVVRLIGVLDKQEIAKIKSELKTTYGHEPNISTV
SPVVGKQLARNALIAVLISSIGIILYVTIRFEWRMALAAIIALLHDAFFIITVFSLTRLEVDLTFIAAVLTIIGYSINDT
IVTFDRIRDLMKKRKVKTVDDLRHIVNRALQQTFTRSINTVLTVLFTVIALLLFGSEAIRNFNLALLAGLLCGVYSSLFI
AAQLWLVWKGNALKKGKGTKKITPETEPHL

Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=392, Percent_Identity=33.6734693877551, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1786610, Length=292, Percent_Identity=33.5616438356164, Blast_Score=155, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 82384; Mature: 82384

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKQSRIVTFFLLVLLLAGVIGPTIQGILHNIKLGLDLQGGFEVLYEVKPAKKGDKIDQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEEECCCCCCCCCCHH
TLQSTVSALNKRINVLGVSEPRVDIEGENRIRVQLAGVKDQNEAREILATQAKLTFRDVN
HHHHHHHHHHHCEEEEECCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEECC
DNVLMDGSDLVQGGAKLSFDENGQPSVAIKLKDADKFRQVTEKVYNMGPPNNILVIWLDF
CCEEECCHHHHCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEC
EEGVDSYQKEAGKADPKFISAASVNQVFNQTDVSIVGNFTVKEAQQLADLLNAGALPVEL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHH
HEIYSTSVGAQFGKNALQTTMLAGIIGVAAIFLFMIWFYRLPGVIAVITLSVYIYLILLL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDWMNGVLTLPGIAALILGVGMAVDANIITYERIKEELKLGKSMMSAFRAGNRGSFATIF
HHHHCCHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DANITTIIAGVVLFIYGTSSVKGFATMLIISIVASFVTAVYGTRLLLGLLVSSRWLDKKP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GYFGVKKSEILNIAETTDETEVPTKFDRWDFIKHSKKFFLFSIALTIAGVISLFAMGLNL
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHC
GIDFTSGTRIEVTSSQPIEAKELSDYFEQLGHKPEDVVLSGTDGKTGVVRLIGVLDKQEI
CEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCHHHH
AKIKSELKTTYGHEPNISTVSPVVGKQLARNALIAVLISSIGIILYVTIRFEWRMALAAI
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHH
IALLHDAFFIITVFSLTRLEVDLTFIAAVLTIIGYSINDTIVTFDRIRDLMKKRKVKTVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCHHH
DLRHIVNRALQQTFTRSINTVLTVLFTVIALLLFGSEAIRNFNLALLAGLLCGVYSSLFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHH
AAQLWLVWKGNALKKGKGTKKITPETEPHL
HHHHHHEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKQSRIVTFFLLVLLLAGVIGPTIQGILHNIKLGLDLQGGFEVLYEVKPAKKGDKIDQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEEECCCCCCCCCCHH
TLQSTVSALNKRINVLGVSEPRVDIEGENRIRVQLAGVKDQNEAREILATQAKLTFRDVN
HHHHHHHHHHHCEEEEECCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEECC
DNVLMDGSDLVQGGAKLSFDENGQPSVAIKLKDADKFRQVTEKVYNMGPPNNILVIWLDF
CCEEECCHHHHCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEC
EEGVDSYQKEAGKADPKFISAASVNQVFNQTDVSIVGNFTVKEAQQLADLLNAGALPVEL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHH
HEIYSTSVGAQFGKNALQTTMLAGIIGVAAIFLFMIWFYRLPGVIAVITLSVYIYLILLL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDWMNGVLTLPGIAALILGVGMAVDANIITYERIKEELKLGKSMMSAFRAGNRGSFATIF
HHHHCCHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DANITTIIAGVVLFIYGTSSVKGFATMLIISIVASFVTAVYGTRLLLGLLVSSRWLDKKP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GYFGVKKSEILNIAETTDETEVPTKFDRWDFIKHSKKFFLFSIALTIAGVISLFAMGLNL
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHC
GIDFTSGTRIEVTSSQPIEAKELSDYFEQLGHKPEDVVLSGTDGKTGVVRLIGVLDKQEI
CEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCHHHH
AKIKSELKTTYGHEPNISTVSPVVGKQLARNALIAVLISSIGIILYVTIRFEWRMALAAI
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHH
IALLHDAFFIITVFSLTRLEVDLTFIAAVLTIIGYSINDTIVTFDRIRDLMKKRKVKTVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCHHH
DLRHIVNRALQQTFTRSINTVLTVLFTVIALLLFGSEAIRNFNLALLAGLLCGVYSSLFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHH
AAQLWLVWKGNALKKGKGTKKITPETEPHL
HHHHHHEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9694879; 9384377 [H]