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The map label for this gene is ahpC [H]

Identifier: 138896143

GI number: 138896143

Start: 2610700

End: 2611263

Strand: Reverse

Name: ahpC [H]

Synonym: GTNG_2506

Alternate gene names: 138896143

Gene position: 2611263-2610700 (Counterclockwise)

Preceding gene: 138896144

Following gene: 138896142

Centisome position: 73.55

GC content: 46.99

Gene sequence:

>564_bases
ATGTCTCTCGTAGGGAAAAAAGTAGAACCTTTCAAAGCACAAGCGTATCATAATGGAGATTTCGTTGAAGTTACGGAACA
AAACTTCCTCGGAAAATGGAGCATCGTTTGCTTCTATCCGGCTGACTTTACGTTCGTATGCCCGACGGAGCTCGAAGATT
TGCAAGACCATTATGCTACGTTCAAAGAACTTGGTGTGGAAGTGTACTCGGTTTCGACCGATACGCACTTTACTCATAAA
GCATGGCATGACACATCGCCGACGATCAGCAAAATTGAATATGTCATGATCGGCGATCCTTCGCACCAATTGTCGCGCAT
GTTTGATGTGCTTGACGAAGAACAAGGTTTGGCTCAACGCGGCACGTTCATTATCGATCCGGACGGCGTCATCCAAGCGG
TGGAAATCAACGCTGACGGCATTGGCCGCAAAGCTAGCGCATTGATTGATAAAATCAAAGCTGCTCAATATGTGCGCAAC
CATCCAGGTGAAGTGTGCCCGGCGAAATGGCAAGAAGGTGCTGAAACGCTGAAACCGAGTCTTGACCTTGTTGGCAAAAT
TTAA

Upstream 100 bases:

>100_bases
GTTATATCTATTGACAAAATACACACTTCTATATGATAATAAATATCGTATTAAAATCATTTTAATTTAAAGACTAGCCA
TTGCAGGAGGTAGATGAAGA

Downstream 100 bases:

>100_bases
GGAGGCATTTGACAATGCTTGATGCTGACATCAAGGCACAACTCGCCCAGTACTTGCAATTGCTTGAAAATGACATTGTC
TTGACAGTAAGCGCGGGAGA

Product: Alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; General stress protein 22; Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLVGKKVEPFKAQAYHNGDFVEVTEQNFLGKWSIVCFYPADFTFVCPTELEDLQDHYATFKELGVEVYSVSTDTHFTHK
AWHDTSPTISKIEYVMIGDPSHQLSRMFDVLDEEQGLAQRGTFIIDPDGVIQAVEINADGIGRKASALIDKIKAAQYVRN
HPGEVCPAKWQEGAETLKPSLDLVGKI

Sequences:

>Translated_187_residues
MSLVGKKVEPFKAQAYHNGDFVEVTEQNFLGKWSIVCFYPADFTFVCPTELEDLQDHYATFKELGVEVYSVSTDTHFTHK
AWHDTSPTISKIEYVMIGDPSHQLSRMFDVLDEEQGLAQRGTFIIDPDGVIQAVEINADGIGRKASALIDKIKAAQYVRN
HPGEVCPAKWQEGAETLKPSLDLVGKI
>Mature_186_residues
SLVGKKVEPFKAQAYHNGDFVEVTEQNFLGKWSIVCFYPADFTFVCPTELEDLQDHYATFKELGVEVYSVSTDTHFTHKA
WHDTSPTISKIEYVMIGDPSHQLSRMFDVLDEEQGLAQRGTFIIDPDGVIQAVEINADGIGRKASALIDKIKAAQYVRNH
PGEVCPAKWQEGAETLKPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=42.7745664739884, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=42.7745664739884, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=39.5604395604396, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=34.6153846153846, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=34.6153846153846, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=34.6153846153846, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=35.8288770053476, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI33188454, Length=84, Percent_Identity=45.2380952380952, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=65.24064171123, Blast_Score=275, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=38.7978142076503, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=38.7978142076503, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=39.5480225988701, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=34.2541436464088, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=36.8131868131868, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319407, Length=165, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=38.4615384615385, Blast_Score=139, Evalue=9e-34,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=38.4615384615385, Blast_Score=139, Evalue=9e-34,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=37.2881355932203, Blast_Score=136, Evalue=7e-33,
Organism=Drosophila melanogaster, GI21357347, Length=185, Percent_Identity=36.2162162162162, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=35.5555555555556, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=35.5555555555556, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=26.6233766233766, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20906; Mature: 20775

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVGKKVEPFKAQAYHNGDFVEVTEQNFLGKWSIVCFYPADFTFVCPTELEDLQDHYAT
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCEEEEEEECCCCEEECCCHHHHHHHHHHH
FKELGVEVYSVSTDTHFTHKAWHDTSPTISKIEYVMIGDPSHQLSRMFDVLDEEQGLAQR
HHHCCEEEEEEECCCCEEECCCCCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHCCHHHC
GTFIIDPDGVIQAVEINADGIGRKASALIDKIKAAQYVRNHPGEVCPAKWQEGAETLKPS
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHCCC
LDLVGKI
HHHHCCC
>Mature Secondary Structure 
SLVGKKVEPFKAQAYHNGDFVEVTEQNFLGKWSIVCFYPADFTFVCPTELEDLQDHYAT
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCEEEEEEECCCCEEECCCHHHHHHHHHHH
FKELGVEVYSVSTDTHFTHKAWHDTSPTISKIEYVMIGDPSHQLSRMFDVLDEEQGLAQR
HHHCCEEEEEEECCCCEEECCCCCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHCCHHHC
GTFIIDPDGVIQAVEINADGIGRKASALIDKIKAAQYVRNHPGEVCPAKWQEGAETLKPS
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHCCC
LDLVGKI
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 8180695; 8012595 [H]