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The map label for this gene is aspS [H]

Identifier: 138896140

GI number: 138896140

Start: 2605684

End: 2607045

Strand: Reverse

Name: aspS [H]

Synonym: GTNG_2503

Alternate gene names: 138896140

Gene position: 2607045-2605684 (Counterclockwise)

Preceding gene: 138896141

Following gene: 138896139

Centisome position: 73.43

GC content: 53.82

Gene sequence:

>1362_bases
ATGTTTCAAACACTTGAGCTTCGTCATAAAGTGGCGAAGGCGGTGCGCAACTTTTTAGACGGCGAACGCTTTTTAGAAGT
GGAGACGCCAATGTTGACGAAAAGCACACCGGAAGGGGCGCGCGATTATTTAGTGCCAAGCCGCGTTCATCCAGGGGAAT
TTTACGCCTTGCCGCAGTCGCCGCAAATTTTTAAGCAGCTTTTGATGGTCGGCGGTTTTGAACGCTATTACCAAATCACT
CGTTGCTTCCGCGATGAAGATTTGCGCGCTGACCGCCAGCCAGAGTTTACGCAAATTGACATTGAAATGTCGTTTGTCGA
CCAAGAAGACATCATCGATTTAACCGAACGGATGATGGCGGCGGTCGTCAAAGCAACTAAAGGGATTGACATTCCGCGCC
CGTTTCCACGCATCACGTATGACGAAGCGATGAGCCGTTACGGTTCCGATAAGCCGGACGTACGTTTTGGCCTTGAGCTT
GTCGATGTGTCGGAAGCGGTCCGCGGCTCCGCGTTTCAAGTGTTCGCCCGCGCCGTTGAGCAAGGTGGTCAAGTGAAGGC
AATCAACGTAAAAGGAGCGGCGAGCCGTTATTCGCGTAAAGACATTGACGCGTTAGCGGAGTTTGCCGGCCGCTACGGAG
CGAAAGGGCTCGCTTGGTTAAAAGTTGAAGGCGGGGAGCTGAAAGGGCCGATCGCCAAGTTTTTCGTCGATGATGAGCAA
ACAGCGCTGCGCCAGCTGCTTGCTGCCGAAGATGGGGATTTGCTGTTGTTTGTTGCTGACGAGAAGGCGATTGTCGCGGC
GGCTCTTGGTGCGTTGCGGTTAAAGCTCGGCAAAGAGCTTGGCTTGATCGATGAAACGAAGCTCGCTTTTTTATGGGTAA
CAGATTGGCCGCTTTTAGAGTACGACGAAGAAGAAGGCCGCTATTACGCCGCCCACCATCCGTTTACGATGCCGGTGCGT
GACGATATCCCGCTGCTTGAGACAAACCCAGGCGCTGTTCGGGCGCAGGCGTATGATTTAGTGTTAAACGGCTATGAGCT
TGGCGGCGGTTCGCTCCGTATTTTTGAGCGCGATGTACAAGAAAAAATGTTCCGCGCTCTAGGATTTGACCAGGAAGAGG
CGCGCCGCCAGTTTGGCTTCCTGCTTGAGGCGTTTGAATATGGCACTCCGCCGCATGGCGGTATCGCCCTCGGCCTCGAT
CGACTTGTGATGCTCTTAGCTGGGCGCACAAACTTGCGCGATACGATCGCCTTCCCGAAAACTGCGAGCGCCAGCTGCCT
GCTTACTGAAGCGCCGGGACCGGTCAGTGAAAAACAACTGAAAGAGTTGCATTTGGCTGTGGTGCTTCCTGACCAGCAAT
AA

Upstream 100 bases:

>100_bases
CAATGAAGCGAAAACGCCGCCGTTTGCGATTGCTGATGACACAGATGCGGCGGAAGATGTGCGTTTGAAATACCGGTACT
TGGATTTGCGCCGCCCGACC

Downstream 100 bases:

>100_bases
CGGCGTCTGAAAGAGAAACATCAGCAGCAGATGGTTCACAAACGCTGAAAAATATGATAAAATGAGAACAACCAATCAAC
CGTCCTGATGTGTTCGTCGG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MFQTLELRHKVAKAVRNFLDGERFLEVETPMLTKSTPEGARDYLVPSRVHPGEFYALPQSPQIFKQLLMVGGFERYYQIT
RCFRDEDLRADRQPEFTQIDIEMSFVDQEDIIDLTERMMAAVVKATKGIDIPRPFPRITYDEAMSRYGSDKPDVRFGLEL
VDVSEAVRGSAFQVFARAVEQGGQVKAINVKGAASRYSRKDIDALAEFAGRYGAKGLAWLKVEGGELKGPIAKFFVDDEQ
TALRQLLAAEDGDLLLFVADEKAIVAAALGALRLKLGKELGLIDETKLAFLWVTDWPLLEYDEEEGRYYAAHHPFTMPVR
DDIPLLETNPGAVRAQAYDLVLNGYELGGGSLRIFERDVQEKMFRALGFDQEEARRQFGFLLEAFEYGTPPHGGIALGLD
RLVMLLAGRTNLRDTIAFPKTASASCLLTEAPGPVSEKQLKELHLAVVLPDQQ

Sequences:

>Translated_453_residues
MFQTLELRHKVAKAVRNFLDGERFLEVETPMLTKSTPEGARDYLVPSRVHPGEFYALPQSPQIFKQLLMVGGFERYYQIT
RCFRDEDLRADRQPEFTQIDIEMSFVDQEDIIDLTERMMAAVVKATKGIDIPRPFPRITYDEAMSRYGSDKPDVRFGLEL
VDVSEAVRGSAFQVFARAVEQGGQVKAINVKGAASRYSRKDIDALAEFAGRYGAKGLAWLKVEGGELKGPIAKFFVDDEQ
TALRQLLAAEDGDLLLFVADEKAIVAAALGALRLKLGKELGLIDETKLAFLWVTDWPLLEYDEEEGRYYAAHHPFTMPVR
DDIPLLETNPGAVRAQAYDLVLNGYELGGGSLRIFERDVQEKMFRALGFDQEEARRQFGFLLEAFEYGTPPHGGIALGLD
RLVMLLAGRTNLRDTIAFPKTASASCLLTEAPGPVSEKQLKELHLAVVLPDQQ
>Mature_453_residues
MFQTLELRHKVAKAVRNFLDGERFLEVETPMLTKSTPEGARDYLVPSRVHPGEFYALPQSPQIFKQLLMVGGFERYYQIT
RCFRDEDLRADRQPEFTQIDIEMSFVDQEDIIDLTERMMAAVVKATKGIDIPRPFPRITYDEAMSRYGSDKPDVRFGLEL
VDVSEAVRGSAFQVFARAVEQGGQVKAINVKGAASRYSRKDIDALAEFAGRYGAKGLAWLKVEGGELKGPIAKFFVDDEQ
TALRQLLAAEDGDLLLFVADEKAIVAAALGALRLKLGKELGLIDETKLAFLWVTDWPLLEYDEEEGRYYAAHHPFTMPVR
DDIPLLETNPGAVRAQAYDLVLNGYELGGGSLRIFERDVQEKMFRALGFDQEEARRQFGFLLEAFEYGTPPHGGIALGLD
RLVMLLAGRTNLRDTIAFPKTASASCLLTEAPGPVSEKQLKELHLAVVLPDQQ

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=459, Percent_Identity=42.9193899782135, Blast_Score=356, Evalue=3e-98,
Organism=Homo sapiens, GI5031815, Length=163, Percent_Identity=30.0613496932515, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI194272210, Length=163, Percent_Identity=30.0613496932515, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788173, Length=454, Percent_Identity=53.9647577092511, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1790571, Length=157, Percent_Identity=35.031847133758, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789256, Length=157, Percent_Identity=31.2101910828025, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32566633, Length=464, Percent_Identity=36.4224137931034, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71994340, Length=166, Percent_Identity=28.9156626506024, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=166, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17535927, Length=166, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325153, Length=497, Percent_Identity=35.010060362173, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6320242, Length=130, Percent_Identity=32.3076923076923, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324256, Length=143, Percent_Identity=27.972027972028, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584738, Length=465, Percent_Identity=40.4301075268817, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24640849, Length=126, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24640851, Length=126, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 50745; Mature: 50745

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTLELRHKVAKAVRNFLDGERFLEVETPMLTKSTPEGARDYLVPSRVHPGEFYALPQS
CCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEECCCC
PQIFKQLLMVGGFERYYQITRCFRDEDLRADRQPEFTQIDIEMSFVDQEDIIDLTERMMA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHH
AVVKATKGIDIPRPFPRITYDEAMSRYGSDKPDVRFGLELVDVSEAVRGSAFQVFARAVE
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEECEEEEEHHHHHCCHHHHHHHHHHH
QGGQVKAINVKGAASRYSRKDIDALAEFAGRYGAKGLAWLKVEGGELKGPIAKFFVDDEQ
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHEEEECCHH
TALRQLLAAEDGDLLLFVADEKAIVAAALGALRLKLGKELGLIDETKLAFLWVTDWPLLE
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEE
YDEEEGRYYAAHHPFTMPVRDDIPLLETNPGAVRAQAYDLVLNGYELGGGSLRIFERDVQ
EECCCCCEEEECCCEECCCCCCCCCEECCCCCEEEEEEEEEEECEEECCCEEEEHHHHHH
EKMFRALGFDQEEARRQFGFLLEAFEYGTPPHGGIALGLDRLVMLLAGRTNLRDTIAFPK
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCC
TASASCLLTEAPGPVSEKQLKELHLAVVLPDQQ
CCCCCEEEECCCCCCCHHHHHHEEEEEEECCCC
>Mature Secondary Structure
MFQTLELRHKVAKAVRNFLDGERFLEVETPMLTKSTPEGARDYLVPSRVHPGEFYALPQS
CCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEECCCC
PQIFKQLLMVGGFERYYQITRCFRDEDLRADRQPEFTQIDIEMSFVDQEDIIDLTERMMA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHH
AVVKATKGIDIPRPFPRITYDEAMSRYGSDKPDVRFGLELVDVSEAVRGSAFQVFARAVE
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEECEEEEEHHHHHCCHHHHHHHHHHH
QGGQVKAINVKGAASRYSRKDIDALAEFAGRYGAKGLAWLKVEGGELKGPIAKFFVDDEQ
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHEEEECCHH
TALRQLLAAEDGDLLLFVADEKAIVAAALGALRLKLGKELGLIDETKLAFLWVTDWPLLE
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEE
YDEEEGRYYAAHHPFTMPVRDDIPLLETNPGAVRAQAYDLVLNGYELGGGSLRIFERDVQ
EECCCCCEEEECCCEECCCCCCCCCEECCCCCEEEEEEEEEEECEEECCCEEEEHHHHHH
EKMFRALGFDQEEARRQFGFLLEAFEYGTPPHGGIALGLDRLVMLLAGRTNLRDTIAFPK
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCCC
TASASCLLTEAPGPVSEKQLKELHLAVVLPDQQ
CCCCCEEEECCCCCCCHHHHHHEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA