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The map label for this gene is hrcA [H]

Identifier: 138896079

GI number: 138896079

Start: 2549899

End: 2550900

Strand: Reverse

Name: hrcA [H]

Synonym: GTNG_2442

Alternate gene names: 138896079

Gene position: 2550900-2549899 (Counterclockwise)

Preceding gene: 138896080

Following gene: 138896078

Centisome position: 71.85

GC content: 48.7

Gene sequence:

>1002_bases
GTGATTATCGACGACTTCATTCGTTCCGGGCAGCCTGTCGGTTCGCGGACGTTATCGAAAAAGCACCAAATCTCGTTCAG
TTCAGCGACGATTCGCAACGAAATGGCGGATTTGGAAGAGCTGGGCTATATTGAAAAAACGCACATTTCCTCGGGCCGTG
TGCCATCGGAAAAAGGGTACCGCTACTACGTTGACCACTTATTGCCGCCGCAGCGGTTGACGAGGACGGATATCCAAAAA
ATCCGCTCCGTGTTCGCTGAACGTATCTACGAGCTCGAGAAATTGGTGCAAAAGTCGGCGCAAATTTTATCCGATTTGAC
GAATTATACGTCGATTGCCCTCGGTCCGGCGTTTAAGGAAAGCAAGCTGAAACGGATGCAGATCATTCCGCTCACTGAAC
AGACGGCTGTTGCCATTGTGGTGACGGATACCGGTCACGTCGAAAACCGGGTCATCACAGTCCCGACAACCGTCAATGCC
GGCGATCTCGAAAAGATGGTCAATATTTTAAACGAGCGTTTGAATGGCGTTCCGCTTATCGATTTAAAAGAAAAAATCGA
GACGGAAGTAGCCGACGTGCTGCGCCGGCATATTCGCAACTACGACAGTATACTCAATACACTGATCGACACGCTCGATA
TTCCTGAAGAGGAAAAAATGTTTTTTGCTGGAAAAACGAATATGTTTAACCAGCCAGAGTTTAGCGACATCCAAAAGGTG
CGCCCGCTTTTGAACATTATCGAGCAAGAAAAGGACATTTACCGTTTGCTCCGCAAGCAAAGTCAAAAAGGGGTGCGAGT
GTCGATCGGGCGGGAAAACGAGCTGAGCGGTATGGAAAACTGCAGTTTGATTACGGCTACGTATTCGATTGGCGATGAAC
CGTTCGGGACGATCGCTATTCTCGGTCCGACGCGCATGGAATATTCACGCGTCATTACCGTGTTAAACCGCGTTGCTACC
GATTTGTCGGCTGCATTGACGAAATGGTATCAAAATCAGTAA

Upstream 100 bases:

>100_bases
GGCGATTTGCTACCCTAATAGTAGATTTAGCACTCGAATTGTTTGAGTGCTAACAGAGGTGAGAAACGTGTTAACGGACC
GCCAACTGTTGATTTTGCAG

Downstream 100 bases:

>100_bases
GGATGGCCATATTGGTTAACGGATGGATGCGCGTCCATCCTTTCCTTGTGGCCATTGATACATAAATCGCAAACCCTGAT
AGGGAGGTGAAGGCAATGGA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIIDDFIRSGQPVGSRTLSKKHQISFSSATIRNEMADLEELGYIEKTHISSGRVPSEKGYRYYVDHLLPPQRLTRTDIQK
IRSVFAERIYELEKLVQKSAQILSDLTNYTSIALGPAFKESKLKRMQIIPLTEQTAVAIVVTDTGHVENRVITVPTTVNA
GDLEKMVNILNERLNGVPLIDLKEKIETEVADVLRRHIRNYDSILNTLIDTLDIPEEEKMFFAGKTNMFNQPEFSDIQKV
RPLLNIIEQEKDIYRLLRKQSQKGVRVSIGRENELSGMENCSLITATYSIGDEPFGTIAILGPTRMEYSRVITVLNRVAT
DLSAALTKWYQNQ

Sequences:

>Translated_333_residues
MIIDDFIRSGQPVGSRTLSKKHQISFSSATIRNEMADLEELGYIEKTHISSGRVPSEKGYRYYVDHLLPPQRLTRTDIQK
IRSVFAERIYELEKLVQKSAQILSDLTNYTSIALGPAFKESKLKRMQIIPLTEQTAVAIVVTDTGHVENRVITVPTTVNA
GDLEKMVNILNERLNGVPLIDLKEKIETEVADVLRRHIRNYDSILNTLIDTLDIPEEEKMFFAGKTNMFNQPEFSDIQKV
RPLLNIIEQEKDIYRLLRKQSQKGVRVSIGRENELSGMENCSLITATYSIGDEPFGTIAILGPTRMEYSRVITVLNRVAT
DLSAALTKWYQNQ
>Mature_333_residues
MIIDDFIRSGQPVGSRTLSKKHQISFSSATIRNEMADLEELGYIEKTHISSGRVPSEKGYRYYVDHLLPPQRLTRTDIQK
IRSVFAERIYELEKLVQKSAQILSDLTNYTSIALGPAFKESKLKRMQIIPLTEQTAVAIVVTDTGHVENRVITVPTTVNA
GDLEKMVNILNERLNGVPLIDLKEKIETEVADVLRRHIRNYDSILNTLIDTLDIPEEEKMFFAGKTNMFNQPEFSDIQKV
RPLLNIIEQEKDIYRLLRKQSQKGVRVSIGRENELSGMENCSLITATYSIGDEPFGTIAILGPTRMEYSRVITVLNRVAT
DLSAALTKWYQNQ

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 37888; Mature: 37888

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDDFIRSGQPVGSRTLSKKHQISFSSATIRNEMADLEELGYIEKTHISSGRVPSEKGY
CCCHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
RYYVDHLLPPQRLTRTDIQKIRSVFAERIYELEKLVQKSAQILSDLTNYTSIALGPAFKE
CEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SKLKRMQIIPLTEQTAVAIVVTDTGHVENRVITVPTTVNAGDLEKMVNILNERLNGVPLI
HHHHHEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEE
DLKEKIETEVADVLRRHIRNYDSILNTLIDTLDIPEEEKMFFAGKTNMFNQPEFSDIQKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCHHHHHHH
RPLLNIIEQEKDIYRLLRKQSQKGVRVSIGRENELSGMENCSLITATYSIGDEPFGTIAI
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCEEEE
LGPTRMEYSRVITVLNRVATDLSAALTKWYQNQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIDDFIRSGQPVGSRTLSKKHQISFSSATIRNEMADLEELGYIEKTHISSGRVPSEKGY
CCCHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
RYYVDHLLPPQRLTRTDIQKIRSVFAERIYELEKLVQKSAQILSDLTNYTSIALGPAFKE
CEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SKLKRMQIIPLTEQTAVAIVVTDTGHVENRVITVPTTVNAGDLEKMVNILNERLNGVPLI
HHHHHEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEE
DLKEKIETEVADVLRRHIRNYDSILNTLIDTLDIPEEEKMFFAGKTNMFNQPEFSDIQKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCHHHHHHH
RPLLNIIEQEKDIYRLLRKQSQKGVRVSIGRENELSGMENCSLITATYSIGDEPFGTIAI
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCEEEE
LGPTRMEYSRVITVLNRVATDLSAALTKWYQNQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA