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The map label for this gene is recU

Identifier: 138895745

GI number: 138895745

Start: 2233338

End: 2233943

Strand: Direct

Name: recU

Synonym: GTNG_2101

Alternate gene names: 138895745

Gene position: 2233338-2233943 (Clockwise)

Preceding gene: 138895742

Following gene: 138895746

Centisome position: 62.91

GC content: 49.5

Gene sequence:

>606_bases
ATGGCACTCAAATACCCGGGCGGAAAAGAGTATCGCGGAAACAGACTAAACGCAGCGCGCCAGCCGATGGCGGCTGATTA
CGCCAACCGTGGCATGACGCTCGAAGAAGACTTAAATGCGACGAATGAATATTACCGGGAGCGCGGCATCGCCGTTGTCT
ATAAAAAACCGACCCCTGTACAAATCGTCCGTGTCGACTACCCGAAACGCAGCGCTGCTGTCATTAAAGAAGCGTATTTC
CGACAGGCGTCCACGACTGACTACAACGGCGTCTACCGCGGCAAATACATCGACTTTGAAGCGAAGGAAACGAAAAACAA
AACGGCGTTTCCGCTAAAAAATTTCCATGCCCACCAAATCCGCCATATGGAGCAAGTGATGGCCCATGGCGGCATTTGCT
TTGCCATTTTGCGCTTTTCTGTGCTGAATGAAACGTACTTGCTTGATGCCTTCCATTTAATTGCCCGTTGGAATGAACAA
GAAGCCGGCGGGCGAAAGTCGATTCCGAAGCGGGAGATCGAGCAATATGGGCATTATATCCCACTTGGCTATCAGCCGAG
AATTGATTATATTAGTGTAGTAGAAAAAGTGTACTTCACCGTATGA

Upstream 100 bases:

>100_bases
GCCATTCGACAAGGACGGCAAGGTCGCCCCATTAAAGAAAAAGAGCGCACATTGCTTGAACGTATGGTATAATAAAAACC
ATTCAAAGGAGATGAACGCC

Downstream 100 bases:

>100_bases
GGTGAAAACTTGTAAGAAAGGCAGGATTTGCTTATGTCTGGTGAATATCGTTCTCGTGTGGAACGAAAGCAGGCAGAGAA
ACAGGCGAAACAAGCGAAAC

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MALKYPGGKEYRGNRLNAARQPMAADYANRGMTLEEDLNATNEYYRERGIAVVYKKPTPVQIVRVDYPKRSAAVIKEAYF
RQASTTDYNGVYRGKYIDFEAKETKNKTAFPLKNFHAHQIRHMEQVMAHGGICFAILRFSVLNETYLLDAFHLIARWNEQ
EAGGRKSIPKREIEQYGHYIPLGYQPRIDYISVVEKVYFTV

Sequences:

>Translated_201_residues
MALKYPGGKEYRGNRLNAARQPMAADYANRGMTLEEDLNATNEYYRERGIAVVYKKPTPVQIVRVDYPKRSAAVIKEAYF
RQASTTDYNGVYRGKYIDFEAKETKNKTAFPLKNFHAHQIRHMEQVMAHGGICFAILRFSVLNETYLLDAFHLIARWNEQ
EAGGRKSIPKREIEQYGHYIPLGYQPRIDYISVVEKVYFTV
>Mature_200_residues
ALKYPGGKEYRGNRLNAARQPMAADYANRGMTLEEDLNATNEYYRERGIAVVYKKPTPVQIVRVDYPKRSAAVIKEAYFR
QASTTDYNGVYRGKYIDFEAKETKNKTAFPLKNFHAHQIRHMEQVMAHGGICFAILRFSVLNETYLLDAFHLIARWNEQE
AGGRKSIPKREIEQYGHYIPLGYQPRIDYISVVEKVYFTV

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECU_GEOTN (A4IQ49)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126198.1
- ProteinModelPortal:   A4IQ49
- SMR:   A4IQ49
- STRING:   A4IQ49
- GeneID:   4967029
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2101
- NMPDR:   fig|420246.5.peg.2008
- eggNOG:   COG3331
- HOGENOM:   HBG571967
- OMA:   GHYIDFE
- ProtClustDB:   PRK02234
- BioCyc:   GTHE420246:GTNG_2101-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00130
- InterPro:   IPR004612
- InterPro:   IPR011335
- PIRSF:   PIRSF037785
- TIGRFAMs:   TIGR00648

Pfam domain/function: PF03838 RecU; SSF52980 Restrict_endonuc_II-like_core

EC number: NA

Molecular weight: Translated: 23327; Mature: 23196

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKYPGGKEYRGNRLNAARQPMAADYANRGMTLEEDLNATNEYYRERGIAVVYKKPTPV
CCCCCCCCCCCCCCCCCHHHCCHHHHHHHCCCCHHHHHCHHHHHHHHCCCEEEEECCCCE
QIVRVDYPKRSAAVIKEAYFRQASTTDYNGVYRGKYIDFEAKETKNKTAFPLKNFHAHQI
EEEEECCCCHHHHHHHHHHHHHCCCCCCCCEECCEEECCCCHHCCCCCCCCCCHHHHHHH
RHMEQVMAHGGICFAILRFSVLNETYLLDAFHLIARWNEQEAGGRKSIPKREIEQYGHYI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCC
PLGYQPRIDYISVVEKVYFTV
CCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALKYPGGKEYRGNRLNAARQPMAADYANRGMTLEEDLNATNEYYRERGIAVVYKKPTPV
CCCCCCCCCCCCCCCCHHHCCHHHHHHHCCCCHHHHHCHHHHHHHHCCCEEEEECCCCE
QIVRVDYPKRSAAVIKEAYFRQASTTDYNGVYRGKYIDFEAKETKNKTAFPLKNFHAHQI
EEEEECCCCHHHHHHHHHHHHHCCCCCCCCEECCEEECCCCHHCCCCCCCCCCHHHHHHH
RHMEQVMAHGGICFAILRFSVLNETYLLDAFHLIARWNEQEAGGRKSIPKREIEQYGHYI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCC
PLGYQPRIDYISVVEKVYFTV
CCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA