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The map label for this gene is uvrX [H]

Identifier: 138895713

GI number: 138895713

Start: 2199127

End: 2200380

Strand: Direct

Name: uvrX [H]

Synonym: GTNG_2069

Alternate gene names: 138895713

Gene position: 2199127-2200380 (Clockwise)

Preceding gene: 138895711

Following gene: 138895714

Centisome position: 61.94

GC content: 45.69

Gene sequence:

>1254_bases
ATGCTGCTTGATATTTCTTGTCTGCCAAAAAATAAAATTTTATGTATCGATATGAAGAGCTTCTACGCTAGTTGCGAATG
CGTCGATCATGGACTGAATCCTCTAGAAGATTATGTCGTCGTTGTCTCTGATAAAAATCGAAGTGGGAGTGTAGTTCTAG
CTGCGTCTCCGAAAATGAAACAGGATTACGGAATCAGGACAGGGAGCCGTCTATATGAAGTGCCTTGCCGTCGCCATATC
CATATTTTTAACGCCCGCATGAAGCGATATTTAGAAATCAGTGTGCAAATCACACAACTGTTTTCTACCTTTGTCCCTTT
TGAAGCGATTCTCACATACAGCGTTGATGAGAGCTGGCTAACCCTAGACGGTACGGAAAAACTACATGGATCTCCCGTGG
AAGCAGCCCAAAAAATACGAAGTGCGATCTGGAATCAATTCGGTCTGCCATCTTGCATTGGCATCGGCCCGAACCGTTTC
ATCAGCAAAGTCGTACTGGATGTATACGCCAAAAAACAAGACATCGCGGAATGTACCTATGAAGAAGTTTCGAAAAAGTT
ATGGCCAGTTCCATTGCGGGAAATCTGGGGCATTGGCAGCCGAATGGAGAAACATTTGAACAATATGGGAATGTATACGC
TTGGAGACGTAGCAAACAGTTCTTTGGATCGTTTACGAAAGAGATTTGGCGTCATAGGAGAACAGCTTTACTATCATGCT
TGGGGCATTGACTTAAGTCCACCTTTTATCGACGCAAGGGCCTTCCCACAAAAAAGTATTGGAAAGGGAATTACGTTGCT
GCGCGATTACTGGCGGGAAAACGAAATTTTAACGGTTGTGTTGGAACTTTGTGAAGAAGTGGCAAAACGGGCTCGTGAAA
TTGGGAAAGTAGGGCGCACCGTTTCGTTTAGCGTGCGCTATTCGCATAATGAAGGAGGATTCCATCAGTCCGTCACCCTT
GATACCGCTACAAACTTAACGATGGATATCTACCGCGTCTGCAAGCAGATTTTCCATAAGTTTTATGACGGGCGAAGCGT
GCGCGTTATTCATGTATCCCTAGGAAATTTAATGGACGAGGAAAGTTTGCAGTTGTCCCTTTTTGAAGATAGAACGAAGG
AACGCGCTCTTGCCAAAGCAATGGATGCGATTCGCGACAAATTTGGTCCCAACGCGCTGTTGCGCGCAGTCAGCTACACA
CCTGGAAGCGTCTCCCGCATCCGCAACGGCTATATAGGAGGGCATCAGGCATGA

Upstream 100 bases:

>100_bases
CTCCTTCTTTTCCCAGTTTCCGCTTGACTTTTTTAACAAAATATAAGAACATATATTCGTAAATAGAACATACGTTCTTA
TAAAGGAGGTCCTTGTGTCG

Downstream 100 bases:

>100_bases
ACCAACGCGATCGAGGAATTATCAAATATTCGCCCTTTTTAATGCCAGAACACCGCAAAATGCTAAAGGAACTTCGTGAA
AAAGAAGAGTGAATCCATCC

Product: ImpB/MucB/SamB family DNA-damage repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLLDISCLPKNKILCIDMKSFYASCECVDHGLNPLEDYVVVVSDKNRSGSVVLAASPKMKQDYGIRTGSRLYEVPCRRHI
HIFNARMKRYLEISVQITQLFSTFVPFEAILTYSVDESWLTLDGTEKLHGSPVEAAQKIRSAIWNQFGLPSCIGIGPNRF
ISKVVLDVYAKKQDIAECTYEEVSKKLWPVPLREIWGIGSRMEKHLNNMGMYTLGDVANSSLDRLRKRFGVIGEQLYYHA
WGIDLSPPFIDARAFPQKSIGKGITLLRDYWRENEILTVVLELCEEVAKRAREIGKVGRTVSFSVRYSHNEGGFHQSVTL
DTATNLTMDIYRVCKQIFHKFYDGRSVRVIHVSLGNLMDEESLQLSLFEDRTKERALAKAMDAIRDKFGPNALLRAVSYT
PGSVSRIRNGYIGGHQA

Sequences:

>Translated_417_residues
MLLDISCLPKNKILCIDMKSFYASCECVDHGLNPLEDYVVVVSDKNRSGSVVLAASPKMKQDYGIRTGSRLYEVPCRRHI
HIFNARMKRYLEISVQITQLFSTFVPFEAILTYSVDESWLTLDGTEKLHGSPVEAAQKIRSAIWNQFGLPSCIGIGPNRF
ISKVVLDVYAKKQDIAECTYEEVSKKLWPVPLREIWGIGSRMEKHLNNMGMYTLGDVANSSLDRLRKRFGVIGEQLYYHA
WGIDLSPPFIDARAFPQKSIGKGITLLRDYWRENEILTVVLELCEEVAKRAREIGKVGRTVSFSVRYSHNEGGFHQSVTL
DTATNLTMDIYRVCKQIFHKFYDGRSVRVIHVSLGNLMDEESLQLSLFEDRTKERALAKAMDAIRDKFGPNALLRAVSYT
PGSVSRIRNGYIGGHQA
>Mature_417_residues
MLLDISCLPKNKILCIDMKSFYASCECVDHGLNPLEDYVVVVSDKNRSGSVVLAASPKMKQDYGIRTGSRLYEVPCRRHI
HIFNARMKRYLEISVQITQLFSTFVPFEAILTYSVDESWLTLDGTEKLHGSPVEAAQKIRSAIWNQFGLPSCIGIGPNRF
ISKVVLDVYAKKQDIAECTYEEVSKKLWPVPLREIWGIGSRMEKHLNNMGMYTLGDVANSSLDRLRKRFGVIGEQLYYHA
WGIDLSPPFIDARAFPQKSIGKGITLLRDYWRENEILTVVLELCEEVAKRAREIGKVGRTVSFSVRYSHNEGGFHQSVTL
DTATNLTMDIYRVCKQIFHKFYDGRSVRVIHVSLGNLMDEESLQLSLFEDRTKERALAKAMDAIRDKFGPNALLRAVSYT
PGSVSRIRNGYIGGHQA

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1786425, Length=365, Percent_Identity=28.2191780821918, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787432, Length=408, Percent_Identity=25, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 47302; Mature: 47302

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDISCLPKNKILCIDMKSFYASCECVDHGLNPLEDYVVVVSDKNRSGSVVLAASPKMK
CEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCH
QDYGIRTGSRLYEVPCRRHIHIFNARMKRYLEISVQITQLFSTFVPFEAILTYSVDESWL
HHCCCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCEE
TLDGTEKLHGSPVEAAQKIRSAIWNQFGLPSCIGIGPNRFISKVVLDVYAKKQDIAECTY
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
EEVSKKLWPVPLREIWGIGSRMEKHLNNMGMYTLGDVANSSLDRLRKRFGVIGEQLYYHA
HHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEE
WGIDLSPPFIDARAFPQKSIGKGITLLRDYWRENEILTVVLELCEEVAKRAREIGKVGRT
ECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCE
VSFSVRYSHNEGGFHQSVTLDTATNLTMDIYRVCKQIFHKFYDGRSVRVIHVSLGNLMDE
EEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ESLQLSLFEDRTKERALAKAMDAIRDKFGPNALLRAVSYTPGSVSRIRNGYIGGHQA
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLLDISCLPKNKILCIDMKSFYASCECVDHGLNPLEDYVVVVSDKNRSGSVVLAASPKMK
CEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCH
QDYGIRTGSRLYEVPCRRHIHIFNARMKRYLEISVQITQLFSTFVPFEAILTYSVDESWL
HHCCCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCEE
TLDGTEKLHGSPVEAAQKIRSAIWNQFGLPSCIGIGPNRFISKVVLDVYAKKQDIAECTY
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
EEVSKKLWPVPLREIWGIGSRMEKHLNNMGMYTLGDVANSSLDRLRKRFGVIGEQLYYHA
HHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEE
WGIDLSPPFIDARAFPQKSIGKGITLLRDYWRENEILTVVLELCEEVAKRAREIGKVGRT
ECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCE
VSFSVRYSHNEGGFHQSVTLDTATNLTMDIYRVCKQIFHKFYDGRSVRVIHVSLGNLMDE
EEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ESLQLSLFEDRTKERALAKAMDAIRDKFGPNALLRAVSYTPGSVSRIRNGYIGGHQA
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]