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The map label for this gene is iolE

Identifier: 138895461

GI number: 138895461

Start: 1919005

End: 1919901

Strand: Reverse

Name: iolE

Synonym: GTNG_1809

Alternate gene names: 138895461

Gene position: 1919901-1919005 (Counterclockwise)

Preceding gene: 138895462

Following gene: 138895460

Centisome position: 54.08

GC content: 43.14

Gene sequence:

>897_bases
ATGTTCAAAGAAAACAAAGTGAAGCTTGGTATTGCTCCAATTGGGTGGACGAATGATGATATGCCTGAGCTGGGGGGTGA
GATTACATTTGAGCAGTGTATTAGTGAAATGGCGCTCGCCGGTTTTGTTGGTTGTGAAGTCGGCAATAAATATCCCCGTG
ATACAAAGATTTTGAAAAAGGCCTTATCCTTACGGGGCTTAAGTATCGCCAGTGCTTGGTTTAGCGCTTTTTTGACCTCA
AAACCATTTGAGGAAACAGCGGAAGCATTTAAAGCACACCGAGATTTTTTATATGAAATGGGCGCAAAAGTCATTGTTGT
TTCTGAACAAGGTAACAGCATCCAAGGACAAATGGAAACACCATTGTTTGATAAAAAGCCAGTTTTTACGGAAGAGGAAT
GGGATCTACTGATCGATGGGTTAAATCGCCTCGGTGATCTGGCTGCAGAAAAGGGAATGAACATTGTCTATCACCATCAT
ATGGGGACGGGTATTCAGACCACAGAGGAGATTGACCGCTTAATGGAGGAAACAGACCCAAAAAAGGTGTCACTTCTTTA
TGATACAGGCCACCTTGTCTTCTCAGGGGAGGATCATTTACATGTCCTAAATAAGCATATAAATCGTATTCGTCATGTTC
ATCTCAAGGATGTACGAATCGAGGTCGCGAATAAGGTTCGCGAGGAAAAAATGAGCTTCTTGCAGGCGGTGAAAGCTGGA
GTATTTACTGTGCCTGGCGATGGTGTGATTGATTTTAAACCAGTATTCGAAGCATTAGATGCCGCCGGCTATGAAGGATG
GTTTGTTGTAGAGGCAGAACAGGATCCAGCCATAGCGAATCCGTTTGAATATGCGTTAAAGGCACGCCAATATATTCGTG
AAACATGCGGTTTATAA

Upstream 100 bases:

>100_bases
TAGCACGCAAATACTGATATAGCATGCGCTGCAAATAGGGATTAAAGGGGGGAGTTAGAGTTCTGTCCGCAGCTTAGAAG
AAAACGGAGGGAAGGGGAAT

Downstream 100 bases:

>100_bases
AGGAGATGAAATGATGAGCCGATTCATTATTTCCAGCCATTCGCCGAATGAAGAAGGGAACGTCGTCCGCGTAACGCCGG
AATCGGCGGGATGGGAGTAT

Product: myo-inositol catabolism protein IolE

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MFKENKVKLGIAPIGWTNDDMPELGGEITFEQCISEMALAGFVGCEVGNKYPRDTKILKKALSLRGLSIASAWFSAFLTS
KPFEETAEAFKAHRDFLYEMGAKVIVVSEQGNSIQGQMETPLFDKKPVFTEEEWDLLIDGLNRLGDLAAEKGMNIVYHHH
MGTGIQTTEEIDRLMEETDPKKVSLLYDTGHLVFSGEDHLHVLNKHINRIRHVHLKDVRIEVANKVREEKMSFLQAVKAG
VFTVPGDGVIDFKPVFEALDAAGYEGWFVVEAEQDPAIANPFEYALKARQYIRETCGL

Sequences:

>Translated_298_residues
MFKENKVKLGIAPIGWTNDDMPELGGEITFEQCISEMALAGFVGCEVGNKYPRDTKILKKALSLRGLSIASAWFSAFLTS
KPFEETAEAFKAHRDFLYEMGAKVIVVSEQGNSIQGQMETPLFDKKPVFTEEEWDLLIDGLNRLGDLAAEKGMNIVYHHH
MGTGIQTTEEIDRLMEETDPKKVSLLYDTGHLVFSGEDHLHVLNKHINRIRHVHLKDVRIEVANKVREEKMSFLQAVKAG
VFTVPGDGVIDFKPVFEALDAAGYEGWFVVEAEQDPAIANPFEYALKARQYIRETCGL
>Mature_298_residues
MFKENKVKLGIAPIGWTNDDMPELGGEITFEQCISEMALAGFVGCEVGNKYPRDTKILKKALSLRGLSIASAWFSAFLTS
KPFEETAEAFKAHRDFLYEMGAKVIVVSEQGNSIQGQMETPLFDKKPVFTEEEWDLLIDGLNRLGDLAAEKGMNIVYHHH
MGTGIQTTEEIDRLMEETDPKKVSLLYDTGHLVFSGEDHLHVLNKHINRIRHVHLKDVRIEVANKVREEKMSFLQAVKAG
VFTVPGDGVIDFKPVFEALDAAGYEGWFVVEAEQDPAIANPFEYALKARQYIRETCGL

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLE_GEOTN (A4IPB5)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001125914.1
- ProteinModelPortal:   A4IPB5
- SMR:   A4IPB5
- STRING:   A4IPB5
- GeneID:   4966742
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_1809
- NMPDR:   fig|420246.5.peg.1741
- eggNOG:   COG1082
- HOGENOM:   HBG654552
- OMA:   DLGKENT
- ProtClustDB:   CLSK810783
- BioCyc:   GTHE420246:GTNG_1809-MONOMER
- HAMAP:   MF_01672
- InterPro:   IPR013022
- InterPro:   IPR012307
- Gene3D:   G3DSA:3.20.20.150

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.44

Molecular weight: Translated: 33480; Mature: 33480

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKENKVKLGIAPIGWTNDDMPELGGEITFEQCISEMALAGFVGCEVGNKYPRDTKILKK
CCCCCCEEEEEEECCCCCCCHHHHCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ALSLRGLSIASAWFSAFLTSKPFEETAEAFKAHRDFLYEMGAKVIVVSEQGNSIQGQMET
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
PLFDKKPVFTEEEWDLLIDGLNRLGDLAAEKGMNIVYHHHMGTGIQTTEEIDRLMEETDP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
KKVSLLYDTGHLVFSGEDHLHVLNKHINRIRHVHLKDVRIEVANKVREEKMSFLQAVKAG
CEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VFTVPGDGVIDFKPVFEALDAAGYEGWFVVEAEQDPAIANPFEYALKARQYIRETCGL
EEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFKENKVKLGIAPIGWTNDDMPELGGEITFEQCISEMALAGFVGCEVGNKYPRDTKILKK
CCCCCCEEEEEEECCCCCCCHHHHCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ALSLRGLSIASAWFSAFLTSKPFEETAEAFKAHRDFLYEMGAKVIVVSEQGNSIQGQMET
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
PLFDKKPVFTEEEWDLLIDGLNRLGDLAAEKGMNIVYHHHMGTGIQTTEEIDRLMEETDP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
KKVSLLYDTGHLVFSGEDHLHVLNKHINRIRHVHLKDVRIEVANKVREEKMSFLQAVKAG
CEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VFTVPGDGVIDFKPVFEALDAAGYEGWFVVEAEQDPAIANPFEYALKARQYIRETCGL
EEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA