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The map label for this gene is yesM [H]

Identifier: 138895438

GI number: 138895438

Start: 1887411

End: 1889141

Strand: Reverse

Name: yesM [H]

Synonym: GTNG_1782

Alternate gene names: 138895438

Gene position: 1889141-1887411 (Counterclockwise)

Preceding gene: 138895439

Following gene: 138895437

Centisome position: 53.21

GC content: 36.97

Gene sequence:

>1731_bases
ATGGTAGATCGTATAAAAAAATGGAACACGCTGCGGAATCAAATATTAGTTATATTCTTATTTGTTATGATCATCGTACT
GTCTATAGTCAGTATCATTACCCTCAGACAAGTATCTTTACTTATCAAGAATAATGCGGAAGATCAAATCAGGCAGACAG
CTGTCGAGGCGAGCGGGAGGATTGATTCACTGTTTGAACAGTTAAATACGGCAACAAAATCTATTATGACGAATCACGAA
GTTCAAAAACTATTTGAACGAATGTATTTAGGGAAGAGCGTAACGTTTGCGGAGTTACAGGGACTAAAAAGCATTGTAAA
TAATATTCAGGCGAACTCTGAAGGAGTTTATTCAGTTGAATTATATACTACAGATTTAAAGCAGATTTTTCCGCTGAACG
ACTCAACTAAAATGTTTCAGCGTATCAATGTAAAATGGATCCATGAAGCCGAACAAGCGAAAGGTAAGTTGGTTTGGATA
GGAGAAGATCCGAAAAATGACGATTTTTATTTGGCGATTAGACGAATATCCTTGATCGAGCATAATTTTGAGAATGGCGG
CTATTTATTGGTCCGGATTAATAAACCATATTTTTCAATTACCGAAGTAAATACGCAACAATATTTATTTGTATTGGATC
ATGAGTGGAATCCGATTTTTTCTAACTTTTCAAAATCAATCGATGTTCTTTCTTTGAAACATCAGTCAACTACAAAGATT
AATCAGATTGAATATATGGTGACGAAGCAATCCTCTACTAAAGGATTTACCGTTGTTATATTAACTCCTGTTAGTGCTCT
TACAAAGGGAATGAATGGCATCCGTCTGGGAATTATTTTTGCCGGTATCATTGGGATAGTGATTTACTTCTTATGTTCTT
TATTTCTTTCCAATATGATTACAAAGCCGATTGTCAACTTGACAAAAACGATGCGACTTGCTAATGAGGGATTATTAACT
ATTGATCCGGAAACGATCACTGTTAATGAAATAAGAGAACTGAATAGCACATACAACCAATTGGTGAGGGAAACGAACCA
TCTGATTAAAACGGTATACCAAAAAGAAATTATTCGTAGCCAAAGTGAGTTAAAAGCGTTGCAGGCACAGATTAATCCTC
ATTTTCTATATAATACTTTGGAATCGTTGCGTTGGTCCTTAGAAGAAAAGGGGGAAGAAGACTTAGCTGATGTGGTCGTT
TCGATGTCGGATTTATTTCGTTATACTATCAGTAGAAATTCAAACGACGATTGGGTCACGTTGAAAGAAGAGTTTGATCA
TATTGGGAATTACATAGAAATTATAAAATTTCGGTTTGGTGACCGCATAAAGTGGTGTTTGCTGTTACCGGAGGCGCTAG
AGCATGTAAAAATCCCTAAGCTTTTAATTCAACCATTGGTTGAGAACGCGGTCGTACATGGTTCGGAAAATCAATTAGCT
TCTTGTACCATTACGGTAGCGGCCGAGCTAGCTTCAGATAGTTATATACAGATCGTTGTGGAGGATGACGGGGTCGGGAT
GGACGAGGAAAGACTGCAGGCTGTCAAACAGGCAATGGATACTGGTGATATTATTTCAAAAAGTGGGAAGGGAATGGCTT
TGCATAATGTCAAAAAACGCTTGCAGCTTTACTATAATGAGGAAATAAGTGATAGTATAACAATTTGCAGCCATAAAAAC
AAAGGAACGAAGATAACGCTGAAAATTCCTGTTAACGGAGGTGAAACGTAA

Upstream 100 bases:

>100_bases
GGATGGTACAGGTGCGGTTGAGAAATTAACATTTCAACGTACGTTGTGTTAATCATAACTTGTAGGACGGCAATTTTACT
ATAGAAAGGTACGTAACGTT

Downstream 100 bases:

>100_bases
TGTACGATAAGACGATCTTAGTCGTAGATGATGAACCAAGAGCGAGAGAGGGGATTAAAAGGGCGTTGGAAAAGTGGGCC
TCTGGCAAACATAGAATTAT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MVDRIKKWNTLRNQILVIFLFVMIIVLSIVSIITLRQVSLLIKNNAEDQIRQTAVEASGRIDSLFEQLNTATKSIMTNHE
VQKLFERMYLGKSVTFAELQGLKSIVNNIQANSEGVYSVELYTTDLKQIFPLNDSTKMFQRINVKWIHEAEQAKGKLVWI
GEDPKNDDFYLAIRRISLIEHNFENGGYLLVRINKPYFSITEVNTQQYLFVLDHEWNPIFSNFSKSIDVLSLKHQSTTKI
NQIEYMVTKQSSTKGFTVVILTPVSALTKGMNGIRLGIIFAGIIGIVIYFLCSLFLSNMITKPIVNLTKTMRLANEGLLT
IDPETITVNEIRELNSTYNQLVRETNHLIKTVYQKEIIRSQSELKALQAQINPHFLYNTLESLRWSLEEKGEEDLADVVV
SMSDLFRYTISRNSNDDWVTLKEEFDHIGNYIEIIKFRFGDRIKWCLLLPEALEHVKIPKLLIQPLVENAVVHGSENQLA
SCTITVAAELASDSYIQIVVEDDGVGMDEERLQAVKQAMDTGDIISKSGKGMALHNVKKRLQLYYNEEISDSITICSHKN
KGTKITLKIPVNGGET

Sequences:

>Translated_576_residues
MVDRIKKWNTLRNQILVIFLFVMIIVLSIVSIITLRQVSLLIKNNAEDQIRQTAVEASGRIDSLFEQLNTATKSIMTNHE
VQKLFERMYLGKSVTFAELQGLKSIVNNIQANSEGVYSVELYTTDLKQIFPLNDSTKMFQRINVKWIHEAEQAKGKLVWI
GEDPKNDDFYLAIRRISLIEHNFENGGYLLVRINKPYFSITEVNTQQYLFVLDHEWNPIFSNFSKSIDVLSLKHQSTTKI
NQIEYMVTKQSSTKGFTVVILTPVSALTKGMNGIRLGIIFAGIIGIVIYFLCSLFLSNMITKPIVNLTKTMRLANEGLLT
IDPETITVNEIRELNSTYNQLVRETNHLIKTVYQKEIIRSQSELKALQAQINPHFLYNTLESLRWSLEEKGEEDLADVVV
SMSDLFRYTISRNSNDDWVTLKEEFDHIGNYIEIIKFRFGDRIKWCLLLPEALEHVKIPKLLIQPLVENAVVHGSENQLA
SCTITVAAELASDSYIQIVVEDDGVGMDEERLQAVKQAMDTGDIISKSGKGMALHNVKKRLQLYYNEEISDSITICSHKN
KGTKITLKIPVNGGET
>Mature_576_residues
MVDRIKKWNTLRNQILVIFLFVMIIVLSIVSIITLRQVSLLIKNNAEDQIRQTAVEASGRIDSLFEQLNTATKSIMTNHE
VQKLFERMYLGKSVTFAELQGLKSIVNNIQANSEGVYSVELYTTDLKQIFPLNDSTKMFQRINVKWIHEAEQAKGKLVWI
GEDPKNDDFYLAIRRISLIEHNFENGGYLLVRINKPYFSITEVNTQQYLFVLDHEWNPIFSNFSKSIDVLSLKHQSTTKI
NQIEYMVTKQSSTKGFTVVILTPVSALTKGMNGIRLGIIFAGIIGIVIYFLCSLFLSNMITKPIVNLTKTMRLANEGLLT
IDPETITVNEIRELNSTYNQLVRETNHLIKTVYQKEIIRSQSELKALQAQINPHFLYNTLESLRWSLEEKGEEDLADVVV
SMSDLFRYTISRNSNDDWVTLKEEFDHIGNYIEIIKFRFGDRIKWCLLLPEALEHVKIPKLLIQPLVENAVVHGSENQLA
SCTITVAAELASDSYIQIVVEDDGVGMDEERLQAVKQAMDTGDIISKSGKGMALHNVKKRLQLYYNEEISDSITICSHKN
KGTKITLKIPVNGGET

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=217, Percent_Identity=29.9539170506912, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788723, Length=211, Percent_Identity=31.2796208530806, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65663; Mature: 65663

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDRIKKWNTLRNQILVIFLFVMIIVLSIVSIITLRQVSLLIKNNAEDQIRQTAVEASGR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
IDSLFEQLNTATKSIMTNHEVQKLFERMYLGKSVTFAELQGLKSIVNNIQANSEGVYSVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
LYTTDLKQIFPLNDSTKMFQRINVKWIHEAEQAKGKLVWIGEDPKNDDFYLAIRRISLIE
EEEECHHHHCCCCCHHHHHHHCCHHEEECHHHCCCCEEEEECCCCCCCCEEEHHHHHHHH
HNFENGGYLLVRINKPYFSITEVNTQQYLFVLDHEWNPIFSNFSKSIDVLSLKHQSTTKI
CCCCCCCEEEEEECCCEEEEEEECCCEEEEEEECCCCHHHHHHHCCCEEEEECCCCCCCH
NQIEYMVTKQSSTKGFTVVILTPVSALTKGMNGIRLGIIFAGIIGIVIYFLCSLFLSNMI
HHEEEEEEECCCCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKPIVNLTKTMRLANEGLLTIDPETITVNEIRELNSTYNQLVRETNHLIKTVYQKEIIRS
HHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSELKALQAQINPHFLYNTLESLRWSLEEKGEEDLADVVVSMSDLFRYTISRNSNDDWVT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LKEEFDHIGNYIEIIKFRFGDRIKWCLLLPEALEHVKIPKLLIQPLVENAVVHGSENQLA
EHHHHHHHCHHHHHHHHHCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHEEECCCCCEE
SCTITVAAELASDSYIQIVVEDDGVGMDEERLQAVKQAMDTGDIISKSGKGMALHNVKKR
EEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
LQLYYNEEISDSITICSHKNKGTKITLKIPVNGGET
HHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MVDRIKKWNTLRNQILVIFLFVMIIVLSIVSIITLRQVSLLIKNNAEDQIRQTAVEASGR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
IDSLFEQLNTATKSIMTNHEVQKLFERMYLGKSVTFAELQGLKSIVNNIQANSEGVYSVE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
LYTTDLKQIFPLNDSTKMFQRINVKWIHEAEQAKGKLVWIGEDPKNDDFYLAIRRISLIE
EEEECHHHHCCCCCHHHHHHHCCHHEEECHHHCCCCEEEEECCCCCCCCEEEHHHHHHHH
HNFENGGYLLVRINKPYFSITEVNTQQYLFVLDHEWNPIFSNFSKSIDVLSLKHQSTTKI
CCCCCCCEEEEEECCCEEEEEEECCCEEEEEEECCCCHHHHHHHCCCEEEEECCCCCCCH
NQIEYMVTKQSSTKGFTVVILTPVSALTKGMNGIRLGIIFAGIIGIVIYFLCSLFLSNMI
HHEEEEEEECCCCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKPIVNLTKTMRLANEGLLTIDPETITVNEIRELNSTYNQLVRETNHLIKTVYQKEIIRS
HHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSELKALQAQINPHFLYNTLESLRWSLEEKGEEDLADVVVSMSDLFRYTISRNSNDDWVT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LKEEFDHIGNYIEIIKFRFGDRIKWCLLLPEALEHVKIPKLLIQPLVENAVVHGSENQLA
EHHHHHHHCHHHHHHHHHCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHEEECCCCCEE
SCTITVAAELASDSYIQIVVEDDGVGMDEERLQAVKQAMDTGDIISKSGKGMALHNVKKR
EEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
LQLYYNEEISDSITICSHKNKGTKITLKIPVNGGET
HHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]