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The map label for this gene is xylB [H]

Identifier: 138895412

GI number: 138895412

Start: 1855422

End: 1856921

Strand: Reverse

Name: xylB [H]

Synonym: GTNG_1756

Alternate gene names: 138895412

Gene position: 1856921-1855422 (Counterclockwise)

Preceding gene: 138895413

Following gene: 138895411

Centisome position: 52.3

GC content: 54.13

Gene sequence:

>1500_bases
TTGGAATATGTCATTGGCGTCGATTTAGGAACAAGTGCGGTCAAAGTATTGCTTGTCGACCGAAACGGGCAAGTTAGAGG
GGAATGGACCGAGTCCTATCCCCTCTACCAGCCGCATTCCGGATATAGTGAGCAGCGCCCAGACGATTGGGTGGAGAAGA
CAATTGTAGCGCTGCGCCGCGTTTGGGAGACCGCCGGCATTTCTCCAGAGTCGGTCGTGGGATTAAGTTTCTCCGGGCAA
ATGCACGGGCTTGTGTTGCTTGATGGTGATGGGAACGTCGTTCGCAACGCGATTTTGTGGAACGACACGCGAACGACAGC
TGAGTGCCGGGAAATTGAGGAGAAAGTTGGCAGAAAGGCGCTGCTCGCAACGGCGAAAAATGAGGCGCTCGAAGGGTTTA
CGCTGCCGAAATTGCTGTGGGTGAAAAAACATGAGCCTCATCTTTACGAGCGGGCGCGAACGTTTTTATTGCCAAAAGAT
TATGTCCGTTTCCGTTTGACTGGGCACATCGCGATGGACGTATCCGATGCAGCGGGAACGCTATTGCTGGATATCGAAAA
GAAAACATGGAGCGAGGAAATTGCACGGGCCGTTGATGTCGATCTTGTCCTTTGTCCGCCGCTTGTCGAGGCAACGGCAT
TGGTTGGGACGTTGCGGCCAGATGTAGCAGAACAGACCGGGCTGCCGGCATCGGTGAAAGTATTTGCCGGCGGGGCGGAC
AATGCCTGCGGCGCGGTGGGCGCCGGCATTTTGGCGGAAGGGAAGATGATGTCGAGCATCGGCACATCCGGTGTCGTCTT
GGCGTATGAACAAAGCGGTGAAAAAGATTTCGCTGGACGAGTGCATTACTTTAACCATGCCGAACCAGATGCCTACTATA
TTATGGGTGTCACGTTGGCGGCTGGGTACAGCTTTGACTGGTGGAAGCGGACGTTTGCGGAAGACGTGCCGTTTGCCGAG
ATTGTAACGCGTGCCGCTGAGTCGCCGATTGGCGCCAACGGCTTGTTGTTTACACCATACCTTGTCGGTGAGCGGACGCC
TTATGCCGACGCCGATATTCGCGGGTCGTTCATCGGTGTTGATTCGGCACAGACGAAATGGGATTTTGCCCGTGCGGTTA
TCGAAGGGATTACGTTTTCACTGAACGAATCGGTTGAGATCATCAAAGCAAGCGGCAAAACGATCGATTCGGTTGTGTCC
ATTGGCGGTGGGGCGAAAAGCGCCGAGTGGCTGCAAATCCAAGCGGATATTTTCGGCATCCCGGTGGAAAAACTGAAAAA
CGAACAAGGGCCAGGACTTGGCGCCGCCATGATTGCCGCGTGCGGCGTCGGCTGGTTTGACTCGCTCAACCAATGCGCCG
ATGCGTTCAAACAAGTCGATGCCGTTGTTGAACCGCAGTCGGATGCCGTTGCGAAGTACAAAGAGCTGTTTTCCATCTAT
CGAGACGTATATCCACACACAAAAGAGATAGCGAAACGGTTAAAAGCGTTTCGGCCGTGA

Upstream 100 bases:

>100_bases
ATACGTCCGGCCGTCTCGAGCGCTTGAAAACGCTGCTGAACCAATACTTGTTGGAAGTCAGCGTGCCGAGTAAAGCCCGC
TTGTGAAAGAGGGATGAGCG

Downstream 100 bases:

>100_bases
CGACAAAACCTCCCCGAATCAATTGATGGTTTGGGGAGGTTTTTGTTTACTCAGGTAATCAGACAGGCTGACCCGCTAGG
TTTGTCCAAGGAGAACTTGA

Product: xylose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MEYVIGVDLGTSAVKVLLVDRNGQVRGEWTESYPLYQPHSGYSEQRPDDWVEKTIVALRRVWETAGISPESVVGLSFSGQ
MHGLVLLDGDGNVVRNAILWNDTRTTAECREIEEKVGRKALLATAKNEALEGFTLPKLLWVKKHEPHLYERARTFLLPKD
YVRFRLTGHIAMDVSDAAGTLLLDIEKKTWSEEIARAVDVDLVLCPPLVEATALVGTLRPDVAEQTGLPASVKVFAGGAD
NACGAVGAGILAEGKMMSSIGTSGVVLAYEQSGEKDFAGRVHYFNHAEPDAYYIMGVTLAAGYSFDWWKRTFAEDVPFAE
IVTRAAESPIGANGLLFTPYLVGERTPYADADIRGSFIGVDSAQTKWDFARAVIEGITFSLNESVEIIKASGKTIDSVVS
IGGGAKSAEWLQIQADIFGIPVEKLKNEQGPGLGAAMIAACGVGWFDSLNQCADAFKQVDAVVEPQSDAVAKYKELFSIY
RDVYPHTKEIAKRLKAFRP

Sequences:

>Translated_499_residues
MEYVIGVDLGTSAVKVLLVDRNGQVRGEWTESYPLYQPHSGYSEQRPDDWVEKTIVALRRVWETAGISPESVVGLSFSGQ
MHGLVLLDGDGNVVRNAILWNDTRTTAECREIEEKVGRKALLATAKNEALEGFTLPKLLWVKKHEPHLYERARTFLLPKD
YVRFRLTGHIAMDVSDAAGTLLLDIEKKTWSEEIARAVDVDLVLCPPLVEATALVGTLRPDVAEQTGLPASVKVFAGGAD
NACGAVGAGILAEGKMMSSIGTSGVVLAYEQSGEKDFAGRVHYFNHAEPDAYYIMGVTLAAGYSFDWWKRTFAEDVPFAE
IVTRAAESPIGANGLLFTPYLVGERTPYADADIRGSFIGVDSAQTKWDFARAVIEGITFSLNESVEIIKASGKTIDSVVS
IGGGAKSAEWLQIQADIFGIPVEKLKNEQGPGLGAAMIAACGVGWFDSLNQCADAFKQVDAVVEPQSDAVAKYKELFSIY
RDVYPHTKEIAKRLKAFRP
>Mature_499_residues
MEYVIGVDLGTSAVKVLLVDRNGQVRGEWTESYPLYQPHSGYSEQRPDDWVEKTIVALRRVWETAGISPESVVGLSFSGQ
MHGLVLLDGDGNVVRNAILWNDTRTTAECREIEEKVGRKALLATAKNEALEGFTLPKLLWVKKHEPHLYERARTFLLPKD
YVRFRLTGHIAMDVSDAAGTLLLDIEKKTWSEEIARAVDVDLVLCPPLVEATALVGTLRPDVAEQTGLPASVKVFAGGAD
NACGAVGAGILAEGKMMSSIGTSGVVLAYEQSGEKDFAGRVHYFNHAEPDAYYIMGVTLAAGYSFDWWKRTFAEDVPFAE
IVTRAAESPIGANGLLFTPYLVGERTPYADADIRGSFIGVDSAQTKWDFARAVIEGITFSLNESVEIIKASGKTIDSVVS
IGGGAKSAEWLQIQADIFGIPVEKLKNEQGPGLGAAMIAACGVGWFDSLNQCADAFKQVDAVVEPQSDAVAKYKELFSIY
RDVYPHTKEIAKRLKAFRP

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=547, Percent_Identity=23.7659963436929, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI164663830, Length=571, Percent_Identity=22.7670753064799, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI18860918, Length=419, Percent_Identity=25.0596658711217, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI41393575, Length=408, Percent_Identity=23.7745098039216, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI42794763, Length=441, Percent_Identity=21.7687074829932, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI189409120, Length=441, Percent_Identity=22.2222222222222, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4504007, Length=441, Percent_Identity=22.2222222222222, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1789987, Length=482, Percent_Identity=37.9668049792531, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1790005, Length=499, Percent_Identity=24.4488977955912, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789168, Length=455, Percent_Identity=26.1538461538462, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787789, Length=511, Percent_Identity=24.853228962818, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1789138, Length=513, Percent_Identity=23.9766081871345, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790361, Length=481, Percent_Identity=21.8295218295218, Blast_Score=102, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=450, Percent_Identity=24.8888888888889, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321633, Length=341, Percent_Identity=24.0469208211144, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24657106, Length=550, Percent_Identity=21.8181818181818, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24657102, Length=550, Percent_Identity=21.8181818181818, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864214, Length=466, Percent_Identity=23.175965665236, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24655555, Length=439, Percent_Identity=21.6400911161731, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655560, Length=439, Percent_Identity=21.6400911161731, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655570, Length=439, Percent_Identity=21.6400911161731, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655574, Length=439, Percent_Identity=21.6400911161731, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655565, Length=439, Percent_Identity=21.6400911161731, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24654573, Length=393, Percent_Identity=23.4096692111959, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21356607, Length=554, Percent_Identity=23.826714801444, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54387; Mature: 54387

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVIGVDLGTSAVKVLLVDRNGQVRGEWTESYPLYQPHSGYSEQRPDDWVEKTIVALRR
CCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VWETAGISPESVVGLSFSGQMHGLVLLDGDGNVVRNAILWNDTRTTAECREIEEKVGRKA
HHHHCCCCHHHEEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHCCHH
LLATAKNEALEGFTLPKLLWVKKHEPHLYERARTFLLPKDYVRFRLTGHIAMDVSDAAGT
HHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHEEEEEEEEEEEEECCCCCE
LLLDIEKKTWSEEIARAVDVDLVLCPPLVEATALVGTLRPDVAEQTGLPASVKVFAGGAD
EEEEECHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCC
NACGAVGAGILAEGKMMSSIGTSGVVLAYEQSGEKDFAGRVHYFNHAEPDAYYIMGVTLA
CCCHHHCCCHHHCCHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEEEEEEEC
AGYSFDWWKRTFAEDVPFAEIVTRAAESPIGANGLLFTPYLVGERTPYADADIRGSFIGV
CCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEECCEEECCCCCCCCCCCCCEEEEC
DSAQTKWDFARAVIEGITFSLNESVEIIKASGKTIDSVVSIGGGAKSAEWLQIQADIFGI
CCCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHHHHCCCCCCCCEEEEEEEEEECC
PVEKLKNEQGPGLGAAMIAACGVGWFDSLNQCADAFKQVDAVVEPQSDAVAKYKELFSIY
CHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RDVYPHTKEIAKRLKAFRP
HHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MEYVIGVDLGTSAVKVLLVDRNGQVRGEWTESYPLYQPHSGYSEQRPDDWVEKTIVALRR
CCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VWETAGISPESVVGLSFSGQMHGLVLLDGDGNVVRNAILWNDTRTTAECREIEEKVGRKA
HHHHCCCCHHHEEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHCCHH
LLATAKNEALEGFTLPKLLWVKKHEPHLYERARTFLLPKDYVRFRLTGHIAMDVSDAAGT
HHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCHHEEEEEEEEEEEEECCCCCE
LLLDIEKKTWSEEIARAVDVDLVLCPPLVEATALVGTLRPDVAEQTGLPASVKVFAGGAD
EEEEECHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCC
NACGAVGAGILAEGKMMSSIGTSGVVLAYEQSGEKDFAGRVHYFNHAEPDAYYIMGVTLA
CCCHHHCCCHHHCCHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEEEEEEEC
AGYSFDWWKRTFAEDVPFAEIVTRAAESPIGANGLLFTPYLVGERTPYADADIRGSFIGV
CCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEECCEEECCCCCCCCCCCCCEEEEC
DSAQTKWDFARAVIEGITFSLNESVEIIKASGKTIDSVVSIGGGAKSAEWLQIQADIFGI
CCCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHHHHCCCCCCCCEEEEEEEEEECC
PVEKLKNEQGPGLGAAMIAACGVGWFDSLNQCADAFKQVDAVVEPQSDAVAKYKELFSIY
CHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RDVYPHTKEIAKRLKAFRP
HHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]