Click here to switch to the map view.

The map label for this gene is kinB [H]

Identifier: 138895378

GI number: 138895378

Start: 1821265

End: 1822593

Strand: Direct

Name: kinB [H]

Synonym: GTNG_1722

Alternate gene names: 138895378

Gene position: 1821265-1822593 (Clockwise)

Preceding gene: 138895371

Following gene: 138895379

Centisome position: 51.3

GC content: 50.26

Gene sequence:

>1329_bases
ATGCTTAGTATTTTCAAAGATTTTTTGCTCAACTTATTTTTTATTCTCCTACCGGTATTTCTCGTTCCGTTTTGGACAGA
GCAAGAAAAGGGACCAAAACGCCTCCGCCTTTATTTGCCAACCGTCTGCTACGCGATCGTGATCGTCTTATGCATCACTC
TCCCCGTCGGCACGGGAAACAGCTATATTTTTGATTTGCGGCAAATTCCGCTTTGGCTCGGCAGCTTGTATGGCGGGACG
GGGGCGGCAGCGTGCTTAGCGATCGTCACCATCACTTACCGAACTTTATTTGGAGGAATCGGCATCTTTATCACTGCCAT
CGTTTCCATCGTCATTGCAGCAGCAAGCAGTTTACTGACCAAAAAGTTTGAGCGGTTGCCAACCAAGCAACGAATATTGC
TCACCACAACGCTCAGCTTCGGTTCTGGCCTGTTGACGGTCGCTCTGACGGGAGGGATGGCGCCCTCTGCTCTCCCCCCG
CTTTCAGTGTCACTCATGTTTTTGCTTGTGCAGCCAGCGAGCATGTTCATCGTCTGCGCTTTTCGAGAGATGGCGCGCCA
CAATATTGCGCTGCGCAAGCGGATCATTCGTGCTGAGAAAATGGAAGCGGTCACCCATTTGGCGGCCTCAATCTCTCATG
AAATCCGCAATCCACTCACCGCGGCACGCGGGTTTATCCAACTGATTGAAGAACAGCCGCTCGCCGCCGATAAACGACGC
CAATATGCACGCATTGCTATGGAAGAGCTCGACCGGGCCGAGGCGATCATTACCGATTATTTGACCTTCGCAAAACCCGC
GCCGGAAACGCCAGAAAAACTGAACGTCAAGCTGGAGATTGAACGAGTCATTGACATCATTCGTCCGTTGGCTAATATGA
GTTGTGTTGATATCAAAACGACGCTGTCCCCTTTCTCTGTCATGGGCGAACGTGAAAAATTCCGCCAATGTTTGCTCAAT
GTCATGAAAAACGCCATCGAAGCGATGCCAAACGGCGGAACGTTGCAAGTATACGTCTCGATCGACGATGGGCGCGTGCT
CATCCGCATTGCCGACACTGGCGTCGGCATGACGAAAGAACAGCTTGAACGGCTTGGCAAGCCATACTTTACCACCAAAG
GGGTAAAAGGCCCCGGTCTTGCAATGATGGTTGTATACCGCATCATTGAATCGATGAACGGCACCATTCGAATCGAAAGC
GAAATACATATGGGGACAACCGTATCGATTTATTTGCCGCTCGCTTCCTCCCTGTCCTCTTCTCTAATTTCTGATAAGGA
AAAACAGCTGTTTGCCCGTTACTGTAAACATAACTGTCCGGATTGTTAG

Upstream 100 bases:

>100_bases
ACCTTAACATCTCGCGCATTTTCCGGTTACAATGTAATATATTCGCAGTTTTTGTAGGAATTCGCGCTATGCAGCTGACG
ATGGGAAAGAGGGTGTCGCG

Downstream 100 bases:

>100_bases
CGTTCTCCTTTTTCGTTTGAAGCAAAACAACAAAAGGATGATCACAACTTCTATCGTCCAAAAAGGATGCCTCATTTTTC
AGGCATCCTTTTCATCTATT

Product: sporulation kinase B-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLSIFKDFLLNLFFILLPVFLVPFWTEQEKGPKRLRLYLPTVCYAIVIVLCITLPVGTGNSYIFDLRQIPLWLGSLYGGT
GAAACLAIVTITYRTLFGGIGIFITAIVSIVIAAASSLLTKKFERLPTKQRILLTTTLSFGSGLLTVALTGGMAPSALPP
LSVSLMFLLVQPASMFIVCAFREMARHNIALRKRIIRAEKMEAVTHLAASISHEIRNPLTAARGFIQLIEEQPLAADKRR
QYARIAMEELDRAEAIITDYLTFAKPAPETPEKLNVKLEIERVIDIIRPLANMSCVDIKTTLSPFSVMGEREKFRQCLLN
VMKNAIEAMPNGGTLQVYVSIDDGRVLIRIADTGVGMTKEQLERLGKPYFTTKGVKGPGLAMMVVYRIIESMNGTIRIES
EIHMGTTVSIYLPLASSLSSSLISDKEKQLFARYCKHNCPDC

Sequences:

>Translated_442_residues
MLSIFKDFLLNLFFILLPVFLVPFWTEQEKGPKRLRLYLPTVCYAIVIVLCITLPVGTGNSYIFDLRQIPLWLGSLYGGT
GAAACLAIVTITYRTLFGGIGIFITAIVSIVIAAASSLLTKKFERLPTKQRILLTTTLSFGSGLLTVALTGGMAPSALPP
LSVSLMFLLVQPASMFIVCAFREMARHNIALRKRIIRAEKMEAVTHLAASISHEIRNPLTAARGFIQLIEEQPLAADKRR
QYARIAMEELDRAEAIITDYLTFAKPAPETPEKLNVKLEIERVIDIIRPLANMSCVDIKTTLSPFSVMGEREKFRQCLLN
VMKNAIEAMPNGGTLQVYVSIDDGRVLIRIADTGVGMTKEQLERLGKPYFTTKGVKGPGLAMMVVYRIIESMNGTIRIES
EIHMGTTVSIYLPLASSLSSSLISDKEKQLFARYCKHNCPDC
>Mature_442_residues
MLSIFKDFLLNLFFILLPVFLVPFWTEQEKGPKRLRLYLPTVCYAIVIVLCITLPVGTGNSYIFDLRQIPLWLGSLYGGT
GAAACLAIVTITYRTLFGGIGIFITAIVSIVIAAASSLLTKKFERLPTKQRILLTTTLSFGSGLLTVALTGGMAPSALPP
LSVSLMFLLVQPASMFIVCAFREMARHNIALRKRIIRAEKMEAVTHLAASISHEIRNPLTAARGFIQLIEEQPLAADKRR
QYARIAMEELDRAEAIITDYLTFAKPAPETPEKLNVKLEIERVIDIIRPLANMSCVDIKTTLSPFSVMGEREKFRQCLLN
VMKNAIEAMPNGGTLQVYVSIDDGRVLIRIADTGVGMTKEQLERLGKPYFTTKGVKGPGLAMMVVYRIIESMNGTIRIES
EIHMGTTVSIYLPLASSLSSSLISDKEKQLFARYCKHNCPDC

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the kinB activity [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=30.327868852459, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788549, Length=229, Percent_Identity=28.82096069869, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786600, Length=215, Percent_Identity=24.1860465116279, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=222, Percent_Identity=26.1261261261261, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=26.4, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=24.4444444444444, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=23.6286919831224, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=22.7906976744186, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=24.2798353909465, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48972; Mature: 48972

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIFKDFLLNLFFILLPVFLVPFWTEQEKGPKRLRLYLPTVCYAIVIVLCITLPVGTGN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHCCCCCCC
SYIFDLRQIPLWLGSLYGGTGAAACLAIVTITYRTLFGGIGIFITAIVSIVIAAASSLLT
CEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKFERLPTKQRILLTTTLSFGSGLLTVALTGGMAPSALPPLSVSLMFLLVQPASMFIVCA
HHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FREMARHNIALRKRIIRAEKMEAVTHLAASISHEIRNPLTAARGFIQLIEEQPLAADKRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QYARIAMEELDRAEAIITDYLTFAKPAPETPEKLNVKLEIERVIDIIRPLANMSCVDIKT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEHHH
TLSPFSVMGEREKFRQCLLNVMKNAIEAMPNGGTLQVYVSIDDGRVLIRIADTGVGMTKE
HCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCHH
QLERLGKPYFTTKGVKGPGLAMMVVYRIIESMNGTIRIESEIHMGTTVSIYLPLASSLSS
HHHHCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCHHHHHH
SLISDKEKQLFARYCKHNCPDC
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSIFKDFLLNLFFILLPVFLVPFWTEQEKGPKRLRLYLPTVCYAIVIVLCITLPVGTGN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHCCCCCCC
SYIFDLRQIPLWLGSLYGGTGAAACLAIVTITYRTLFGGIGIFITAIVSIVIAAASSLLT
CEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKFERLPTKQRILLTTTLSFGSGLLTVALTGGMAPSALPPLSVSLMFLLVQPASMFIVCA
HHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FREMARHNIALRKRIIRAEKMEAVTHLAASISHEIRNPLTAARGFIQLIEEQPLAADKRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QYARIAMEELDRAEAIITDYLTFAKPAPETPEKLNVKLEIERVIDIIRPLANMSCVDIKT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEHHH
TLSPFSVMGEREKFRQCLLNVMKNAIEAMPNGGTLQVYVSIDDGRVLIRIADTGVGMTKE
HCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCHH
QLERLGKPYFTTKGVKGPGLAMMVVYRIIESMNGTIRIESEIHMGTTVSIYLPLASSLSS
HHHHCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCHHHHHH
SLISDKEKQLFARYCKHNCPDC
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8497199; 9274030; 9384377 [H]