Click here to switch to the map view.

The map label for this gene is pncA [H]

Identifier: 138895362

GI number: 138895362

Start: 1798208

End: 1798759

Strand: Reverse

Name: pncA [H]

Synonym: GTNG_1706

Alternate gene names: 138895362

Gene position: 1798759-1798208 (Counterclockwise)

Preceding gene: 138895363

Following gene: 138895361

Centisome position: 50.66

GC content: 51.63

Gene sequence:

>552_bases
ATGGGGAAAGCACTGATTAACATCGACTACACCGTTGATTTCATTGCCGATGACGGTGCGCTCACATGCGGGAAGCCGGG
ACAAGTGATTGAGGACGAGCTTGTGCGTGTAACGAAACAGTTTATTGACCATGGCGACTTTGTCGTTTTTGCCATTGACA
AGCATACGGAAGAAGACCATTATCATCCGGAGACAAAGCTGTTTCCGCCGCATAATATCGAGGGGACGAAAGGACGGAAG
CTGTATGGGGAGCTAGAGACGTTGTACCAAGCGAATAAGCATAAGAAGAATGTGTATTGGATGGATAAAACGCGCTACAG
CGCGTTCGCCGGAACCGACTTAGAGCTGAAGTTGCGCGAGAGAGGCATCACGGAAGTGCATTTGGTCGGGTGCTGCACCG
ATATTTGCGTCCTTCATACGGCGGTTGATGCATACAACAAAGGATTTCGCATCGTCGTTTATCGGCGGGCGGTCGCGAGC
TTTGATGCGGCCGGGCACGAGTGGGCGCTTCGGCATTTTCGCCATGCGCTAGGCGCAGAAATAGTGGAATAA

Upstream 100 bases:

>100_bases
GTTCAACTCAGAGCAAGAGGCGCTCCGTTCGGGAGATTCCGTTTGCTCGGATGTTGACTGCTTGGATACAGGAGAAGAAA
AAAAGGGGGAGTGATGCAAA

Downstream 100 bases:

>100_bases
TGGTCGAAACATGGTAGAATAGACCGTGGACATTCTTTTTCATCCGGTGGCGTGTTCATTTGGTTGTTGGAGGTTGCAAA
AATGGGTGGAACATATGCAG

Product: pyrazinamidase: nicotinamidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MGKALINIDYTVDFIADDGALTCGKPGQVIEDELVRVTKQFIDHGDFVVFAIDKHTEEDHYHPETKLFPPHNIEGTKGRK
LYGELETLYQANKHKKNVYWMDKTRYSAFAGTDLELKLRERGITEVHLVGCCTDICVLHTAVDAYNKGFRIVVYRRAVAS
FDAAGHEWALRHFRHALGAEIVE

Sequences:

>Translated_183_residues
MGKALINIDYTVDFIADDGALTCGKPGQVIEDELVRVTKQFIDHGDFVVFAIDKHTEEDHYHPETKLFPPHNIEGTKGRK
LYGELETLYQANKHKKNVYWMDKTRYSAFAGTDLELKLRERGITEVHLVGCCTDICVLHTAVDAYNKGFRIVVYRRAVAS
FDAAGHEWALRHFRHALGAEIVE
>Mature_182_residues
GKALINIDYTVDFIADDGALTCGKPGQVIEDELVRVTKQFIDHGDFVVFAIDKHTEEDHYHPETKLFPPHNIEGTKGRKL
YGELETLYQANKHKKNVYWMDKTRYSAFAGTDLELKLRERGITEVHLVGCCTDICVLHTAVDAYNKGFRIVVYRRAVASF
DAAGHEWALRHFRHALGAEIVE

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 20834; Mature: 20703

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKALINIDYTVDFIADDGALTCGKPGQVIEDELVRVTKQFIDHGDFVVFAIDKHTEEDH
CCCEEEEEEEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
YHPETKLFPPHNIEGTKGRKLYGELETLYQANKHKKNVYWMDKTRYSAFAGTDLELKLRE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCEEEEEHH
RGITEVHLVGCCTDICVLHTAVDAYNKGFRIVVYRRAVASFDAAGHEWALRHFRHALGAE
CCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHH
IVE
HCC
>Mature Secondary Structure 
GKALINIDYTVDFIADDGALTCGKPGQVIEDELVRVTKQFIDHGDFVVFAIDKHTEEDH
CCEEEEEEEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
YHPETKLFPPHNIEGTKGRKLYGELETLYQANKHKKNVYWMDKTRYSAFAGTDLELKLRE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCEEEEEHH
RGITEVHLVGCCTDICVLHTAVDAYNKGFRIVVYRRAVASFDAAGHEWALRHFRHALGAE
CCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHH
IVE
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]