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The map label for this gene is treR [H]

Identifier: 138895298

GI number: 138895298

Start: 1729739

End: 1730452

Strand: Reverse

Name: treR [H]

Synonym: GTNG_1642

Alternate gene names: 138895298

Gene position: 1730452-1729739 (Counterclockwise)

Preceding gene: 138895299

Following gene: 138895297

Centisome position: 48.74

GC content: 46.78

Gene sequence:

>714_bases
ATGCATGAAAACAAATATTTAGCTATTTATCACGATCTTGCTTCCCGCATCCGCGACGGGGAATGGAAGGCGTACGATAA
GTTGCCGTCAGAAAATGAGCTGGCTGTTCGGTACAAGACATCGCGCGAGACGATCCGTAAGGCGCTCAATTTATTGTCCG
AACACGGGTATATTCAAAAAATGAAAGGAAAAGGGTCGATCGTGCTTGATGTTGGTAGATACGCCTTTCCCGTCTCCGGG
TTGGTCAGCTTTAAAGAACTGGCGCAAACGATGAAACAGCCGGTGCGGACGATCGTCCATGAACTGGAACTGATCAAACC
GGATGCTGAGCTTAAACAGCAACTGCGTGCAACAAGCAAAGATGATGTGTGGAAAGTCGTGCGTGTCCGTGAAATTGACG
GGGAGCGGATTATTTTAGATAAAGACTTTTTCTTAAAAAAGAACGTCCCGCTGTTGACAAAAGAGATTTGTGAAGACTCG
ATTTATGAATACTTAGAAACCAAACTGCATTTGCCGATCAGCTTTGCGAAAAAAGAAATGTCCGTCGATGAGGCAACCGA
GGAAGACCGTCGCTATTTGGATCTCAATGGCGATGACCGCGTCGTCGTCGTTAGAAACTACGTCTATTTAAACGACGCCA
CCTTGTTCCAATACACGGAATCGCGGCACCGACTTGACAAGTTCCGGTTTGTCGATTTCGCGCGTCGGAAATGA

Upstream 100 bases:

>100_bases
CCGGACGCACCGGCCGATTTCCGTCGTATGGCGCTACGTCCGTACGAATCGGTTGTTTATCTTCTGCGCCGTCCATGATA
CAATACAGACGGTGATGATG

Downstream 100 bases:

>100_bases
CAGAGCCCGACCGTGTGTGATTAGATTAGGCGGTGACGGATACGTTTTGATGCCACGCTGCGTCTTACGACGCGGCGTTT
TTTTATTGTTTGTTTTGATA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MHENKYLAIYHDLASRIRDGEWKAYDKLPSENELAVRYKTSRETIRKALNLLSEHGYIQKMKGKGSIVLDVGRYAFPVSG
LVSFKELAQTMKQPVRTIVHELELIKPDAELKQQLRATSKDDVWKVVRVREIDGERIILDKDFFLKKNVPLLTKEICEDS
IYEYLETKLHLPISFAKKEMSVDEATEEDRRYLDLNGDDRVVVVRNYVYLNDATLFQYTESRHRLDKFRFVDFARRK

Sequences:

>Translated_237_residues
MHENKYLAIYHDLASRIRDGEWKAYDKLPSENELAVRYKTSRETIRKALNLLSEHGYIQKMKGKGSIVLDVGRYAFPVSG
LVSFKELAQTMKQPVRTIVHELELIKPDAELKQQLRATSKDDVWKVVRVREIDGERIILDKDFFLKKNVPLLTKEICEDS
IYEYLETKLHLPISFAKKEMSVDEATEEDRRYLDLNGDDRVVVVRNYVYLNDATLFQYTESRHRLDKFRFVDFARRK
>Mature_237_residues
MHENKYLAIYHDLASRIRDGEWKAYDKLPSENELAVRYKTSRETIRKALNLLSEHGYIQKMKGKGSIVLDVGRYAFPVSG
LVSFKELAQTMKQPVRTIVHELELIKPDAELKQQLRATSKDDVWKVVRVREIDGERIILDKDFFLKKNVPLLTKEICEDS
IYEYLETKLHLPISFAKKEMSVDEATEEDRRYLDLNGDDRVVVVRNYVYLNDATLFQYTESRHRLDKFRFVDFARRK

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=234, Percent_Identity=29.9145299145299, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790540, Length=236, Percent_Identity=20.3389830508475, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87082252, Length=195, Percent_Identity=25.6410256410256, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27977; Mature: 27977

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHENKYLAIYHDLASRIRDGEWKAYDKLPSENELAVRYKTSRETIRKALNLLSEHGYIQK
CCCCCEEEEEHHHHHHHCCCCCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEE
MKGKGSIVLDVGRYAFPVSGLVSFKELAQTMKQPVRTIVHELELIKPDAELKQQLRATSK
ECCCCCEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
DDVWKVVRVREIDGERIILDKDFFLKKNVPLLTKEICEDSIYEYLETKLHLPISFAKKEM
CHHHHHHHEEECCCCEEEEECCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
SVDEATEEDRRYLDLNGDDRVVVVRNYVYLNDATLFQYTESRHRLDKFRFVDFARRK
CHHHCCHHCCEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHENKYLAIYHDLASRIRDGEWKAYDKLPSENELAVRYKTSRETIRKALNLLSEHGYIQK
CCCCCEEEEEHHHHHHHCCCCCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEE
MKGKGSIVLDVGRYAFPVSGLVSFKELAQTMKQPVRTIVHELELIKPDAELKQQLRATSK
ECCCCCEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
DDVWKVVRVREIDGERIILDKDFFLKKNVPLLTKEICEDSIYEYLETKLHLPISFAKKEM
CHHHHHHHEEECCCCEEEEECCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
SVDEATEEDRRYLDLNGDDRVVVVRNYVYLNDATLFQYTESRHRLDKFRFVDFARRK
CHHHCCHHCCEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]