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The map label for this gene is yclK [H]

Identifier: 138895266

GI number: 138895266

Start: 1694948

End: 1696318

Strand: Direct

Name: yclK [H]

Synonym: GTNG_1608

Alternate gene names: 138895266

Gene position: 1694948-1696318 (Clockwise)

Preceding gene: 138895265

Following gene: 138895267

Centisome position: 47.74

GC content: 37.93

Gene sequence:

>1371_bases
ATGAGAAAAATTTCGTTTAAATTGGGACTATTATTTTTTGTATTCGTATTAGGAATAGAGACAGTTTTATTTGCGTCTTT
ATATGTTACTCTGGTTCATTCTAGAATTAATGAGGAATTTGAACAGCTGTTGGCAAGGGGGAATAATCATCGCGATGTGT
TAGAAAAAAGTTATAACCCTTCTACGTTAGAGCATGTCACGATGATGGAATCTGAGGCGGAGACGGACGTCGTTATTACC
AATGACAAGGGGAAGATACTGTATTTTTCAGATCATATTTTACCATTTGCTAAAAGAGTAATAAAAAAAGCAAATAAAAA
CATTCCCTATGGCGGTATGATTGTGCAAAAAAATTGGCAAAAAGAGTCGCATATTTCAACGGTAAGCCCGATTCGGATTG
ACGGCAAGATCAAAGGGTATGTCTATATGTTTCAAAATACGGCTTCCATTCAAAACATGATTTATAAGTTAAAACATCAT
TTCCTTATGGTTGGAATTCTTTCGGTATTTTTAACGATTATTACGATTGCTTTCTTATCAAGAGTCATTACCATTCCTCT
CATTCGCATGAAACAGGCGACCGAAAAATTGAGCAAAGGGGATTTTTCGGTTCGTTTGCAAGTAAAAGGGGGGGACGAAT
TGGCGGAATTAGGGAAAGCTATTCAAACATTGGCGAGGGATTTAGAATACTTAAAAAAAGAAAGAAACGAATTTCTCGCC
AGTATTTCTCATGAGCTTCGCACCCCGCTCACTTATGTAAAAGGGTATGCTGATATAGCTAGGAGACCCAACATGGAGGA
AGAGGAGAGAAATCGATATTTGTCCATTATCTACGAAGAAGCAGAGCATATGCAAAAGTTGGTGAAGGATCTTTTTGAAT
TAGCGAAGATGGATCAACATTCCTTTCAAATCCATAAGGAACCTACAAACTTATGTTCTTTCTTAAAAAAATTGCATGAC
AAAATGCATCCTGCGTTTCAAGCTAAAAAAATGTCTTTGGTATATCAATGTGAAAAAAACATAACTGTCCATATAGACCA
AAAACGATTTGAGCAAGTGATGATAAATTTGTTAGACAATGCTTTAAAATATGCTGATCAAGGTTCTACCGTCTCTATTG
ATGCAAGAGCGGAGAAAGACAACATTGTGATGATTGTTTCAGACGAAGGCAGAGGAATCCCTGAAGAGGATTTGCCGCAT
ATTTTTGAACGGTTTTACCGAGTGGATAAATCAAGATCAAGAACCAGCGGCGGAACAGGACTGGGACTGGCCATCGCCAA
GGAAATTGTGGAAGCGCACGGAGGGTCGATTTACGCCGCAAGTGAATATGGAAAAGGAACAAACATGATCATTACATTGC
CGGAGGGATAA

Upstream 100 bases:

>100_bases
AATTACTTCTCCTTTATAAATCGCCCAAAGCCATAAAAAACAGCTTTTCTAAACTATATAGAAATTAATTGAATTGCGCT
GAATAAGGAAGGGACCAAAA

Downstream 100 bases:

>100_bases
GCTTGTACACGATTTTACTGGTTGACGATGAAAAACGAATGTTAGATTTACTTGATCTTTATCTTTCGCCTAAAGGATAT
CATTGCGTAAAGTGTGAGTC

Product: two component system histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MRKISFKLGLLFFVFVLGIETVLFASLYVTLVHSRINEEFEQLLARGNNHRDVLEKSYNPSTLEHVTMMESEAETDVVIT
NDKGKILYFSDHILPFAKRVIKKANKNIPYGGMIVQKNWQKESHISTVSPIRIDGKIKGYVYMFQNTASIQNMIYKLKHH
FLMVGILSVFLTIITIAFLSRVITIPLIRMKQATEKLSKGDFSVRLQVKGGDELAELGKAIQTLARDLEYLKKERNEFLA
SISHELRTPLTYVKGYADIARRPNMEEEERNRYLSIIYEEAEHMQKLVKDLFELAKMDQHSFQIHKEPTNLCSFLKKLHD
KMHPAFQAKKMSLVYQCEKNITVHIDQKRFEQVMINLLDNALKYADQGSTVSIDARAEKDNIVMIVSDEGRGIPEEDLPH
IFERFYRVDKSRSRTSGGTGLGLAIAKEIVEAHGGSIYAASEYGKGTNMIITLPEG

Sequences:

>Translated_456_residues
MRKISFKLGLLFFVFVLGIETVLFASLYVTLVHSRINEEFEQLLARGNNHRDVLEKSYNPSTLEHVTMMESEAETDVVIT
NDKGKILYFSDHILPFAKRVIKKANKNIPYGGMIVQKNWQKESHISTVSPIRIDGKIKGYVYMFQNTASIQNMIYKLKHH
FLMVGILSVFLTIITIAFLSRVITIPLIRMKQATEKLSKGDFSVRLQVKGGDELAELGKAIQTLARDLEYLKKERNEFLA
SISHELRTPLTYVKGYADIARRPNMEEEERNRYLSIIYEEAEHMQKLVKDLFELAKMDQHSFQIHKEPTNLCSFLKKLHD
KMHPAFQAKKMSLVYQCEKNITVHIDQKRFEQVMINLLDNALKYADQGSTVSIDARAEKDNIVMIVSDEGRGIPEEDLPH
IFERFYRVDKSRSRTSGGTGLGLAIAKEIVEAHGGSIYAASEYGKGTNMIITLPEG
>Mature_456_residues
MRKISFKLGLLFFVFVLGIETVLFASLYVTLVHSRINEEFEQLLARGNNHRDVLEKSYNPSTLEHVTMMESEAETDVVIT
NDKGKILYFSDHILPFAKRVIKKANKNIPYGGMIVQKNWQKESHISTVSPIRIDGKIKGYVYMFQNTASIQNMIYKLKHH
FLMVGILSVFLTIITIAFLSRVITIPLIRMKQATEKLSKGDFSVRLQVKGGDELAELGKAIQTLARDLEYLKKERNEFLA
SISHELRTPLTYVKGYADIARRPNMEEEERNRYLSIIYEEAEHMQKLVKDLFELAKMDQHSFQIHKEPTNLCSFLKKLHD
KMHPAFQAKKMSLVYQCEKNITVHIDQKRFEQVMINLLDNALKYADQGSTVSIDARAEKDNIVMIVSDEGRGIPEEDLPH
IFERFYRVDKSRSRTSGGTGLGLAIAKEIVEAHGGSIYAASEYGKGTNMIITLPEG

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=34.8920863309352, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786600, Length=279, Percent_Identity=30.8243727598566, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786783, Length=306, Percent_Identity=30.0653594771242, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=31.4655172413793, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=34.9775784753363, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790346, Length=347, Percent_Identity=26.8011527377522, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787894, Length=301, Percent_Identity=26.9102990033223, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=28.1512605042017, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789149, Length=406, Percent_Identity=24.384236453202, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=26.7543859649123, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790861, Length=324, Percent_Identity=23.1481481481481, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081816, Length=339, Percent_Identity=25.3687315634218, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=318, Percent_Identity=27.3584905660377, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082128, Length=317, Percent_Identity=23.3438485804416, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=26.3636363636364, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789808, Length=290, Percent_Identity=24.8275862068966, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790551, Length=286, Percent_Identity=26.2237762237762, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787374, Length=238, Percent_Identity=27.7310924369748, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789403, Length=225, Percent_Identity=30.2222222222222, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52169; Mature: 52169

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKISFKLGLLFFVFVLGIETVLFASLYVTLVHSRINEEFEQLLARGNNHRDVLEKSYNP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
STLEHVTMMESEAETDVVITNDKGKILYFSDHILPFAKRVIKKANKNIPYGGMIVQKNWQ
CHHHHHHHHHCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCC
KESHISTVSPIRIDGKIKGYVYMFQNTASIQNMIYKLKHHFLMVGILSVFLTIITIAFLS
CHHCCCCCCCEEECCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVITIPLIRMKQATEKLSKGDFSVRLQVKGGDELAELGKAIQTLARDLEYLKKERNEFLA
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISHELRTPLTYVKGYADIARRPNMEEEERNRYLSIIYEEAEHMQKLVKDLFELAKMDQH
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFQIHKEPTNLCSFLKKLHDKMHPAFQAKKMSLVYQCEKNITVHIDQKRFEQVMINLLDN
CEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHH
ALKYADQGSTVSIDARAEKDNIVMIVSDEGRGIPEEDLPHIFERFYRVDKSRSRTSGGTG
HHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
LGLAIAKEIVEAHGGSIYAASEYGKGTNMIITLPEG
HHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCC
>Mature Secondary Structure
MRKISFKLGLLFFVFVLGIETVLFASLYVTLVHSRINEEFEQLLARGNNHRDVLEKSYNP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
STLEHVTMMESEAETDVVITNDKGKILYFSDHILPFAKRVIKKANKNIPYGGMIVQKNWQ
CHHHHHHHHHCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCC
KESHISTVSPIRIDGKIKGYVYMFQNTASIQNMIYKLKHHFLMVGILSVFLTIITIAFLS
CHHCCCCCCCEEECCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVITIPLIRMKQATEKLSKGDFSVRLQVKGGDELAELGKAIQTLARDLEYLKKERNEFLA
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISHELRTPLTYVKGYADIARRPNMEEEERNRYLSIIYEEAEHMQKLVKDLFELAKMDQH
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFQIHKEPTNLCSFLKKLHDKMHPAFQAKKMSLVYQCEKNITVHIDQKRFEQVMINLLDN
CEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCEEEECHHHHHHHHHHHHHH
ALKYADQGSTVSIDARAEKDNIVMIVSDEGRGIPEEDLPHIFERFYRVDKSRSRTSGGTG
HHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
LGLAIAKEIVEAHGGSIYAASEYGKGTNMIITLPEG
HHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]