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The map label for this gene is yvbW [H]

Identifier: 138895199

GI number: 138895199

Start: 1620508

End: 1621881

Strand: Reverse

Name: yvbW [H]

Synonym: GTNG_1539

Alternate gene names: 138895199

Gene position: 1621881-1620508 (Counterclockwise)

Preceding gene: 138895207

Following gene: 138895194

Centisome position: 45.68

GC content: 55.6

Gene sequence:

>1374_bases
ATGGAACATTCGCGCCCATCGTTGCAAAAAGGGCTGTTGCCTCGCCATGTACAGTTGATGGCGCTAGGCGGCATGATCGG
CACCGGTATTTTCAAAGGAAGCGCCGATACGATTCACATCGCCGGACCAAGTGTCGTTCTCACATATCTCCTCGGCGGGG
CGCTGCTGTTTCTTATTATGGCCGCATTAGCCGAGATGGCCCTCGCCTATCCGGGCGAAAACGTTCAACATTTGATCCGC
CGGGCGTTTGGCTTTCGTTGGTCGTTTCTCGTCGGGTGGCTGTATTGGGCGAACTGGACATTGGTCACAGTCGTCGAGCT
GCTTGCGGCAGGAAGTTTTTTACGCTATTGGATGCCATCTGTGCCGCTTTGGTTGCTCGCCCTTGGCTGCGCGTTATTGA
TTATCGTGCTGAACTTGTTTCCGGTTCGATACTATGGAGAAACGGAATTTTGGCTCGCTGGATTGAAAGTGGCGGCGCTA
GTTGTATTCATCTTGCTTGGGGCCGGCATGTGGTTTGGTGTGATCGAAGGGGCGAACGGAGACCCATGGGCCCGTTATGC
GACCTACGATACTTGGTTTCCGCATGGGGTTGGGGGCATGATCAGCGCCTTGCTTGTGGTTGTGTTTTCATACGGTGGAG
CCGAGCTGATCGGTGTGGCGGTGACAGAGATGAAAGACGCCGACCGGGTGCTGCCGCGGGTCATCAAAACCACGATATGG
CGGGTCATCGGCTTTTACGTACTGCCGATCGCCATCATTTGCGGCATCATGCCGTGGAACGCCGTATCGGCGGAAAACAG
CCCGTTCGTCCAAGTGCTCGAGGCAACGGGCATTTCGGGTGCCGCCCATGTGATGAACGCGATCCTGCTTATTGCCGTCT
TATCAGCAGCCAACACCGGGGTGTACGCCACTTCTCGCTTGCTCTTTTCAATGGCCGAACAAGGAGAAGCAAGCCGCCGC
TTGTTACGGACGACACGACACGGGGTGCCGCTTTACGGCATGGGAATGGTCGCTCTCTGCATTGCCGCAGGAGTCGTCGG
TGCGTACTTGGCGCCAGGGCGGATCATCGGCGAGTTGATGACGATCCCTGGGTTTACGGTGCTGATCGTCTGGATGATGA
TCGGAGCGGCCCAACTCAAACTGCGGCCGAATTACGACACGAATCCGTTCTTTCGCGTCAAAGGATTTCCGTACACGACG
AGCATCGCCGTCGTGTCGCTCGGCGCGATTTGGGTGAGTTTTTTATTCCAGCGCGAGCATCGAATCGGCTCCGTTCTTTG
CCTGATGATTTTGGCGATTCTCGCAATGTATGGATCCATCAAAGAAAAACAGCGCCGGCTGCCGGAACAGAACATTGATG
AACAATCCGCATAA

Upstream 100 bases:

>100_bases
ATTATATTCTAAAACTATCTTTTTCGCTTAACTGCATAAAAGCATAAAAGCAAAAAAGTGCATCATGGAAGGAACTTCGT
ACGAGAAAGGTTGTTGCTGT

Downstream 100 bases:

>100_bases
ACAAGAATGCACAAAGAAAAGGTGCCGTTGTCGTTATGGACGGCGCCTATTTTCTTGTTGCCCCCAACTGTTTCCGCGCC
ATTCATCCCACGCCCGCCAG

Product: aromatic amino acid permease

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MEHSRPSLQKGLLPRHVQLMALGGMIGTGIFKGSADTIHIAGPSVVLTYLLGGALLFLIMAALAEMALAYPGENVQHLIR
RAFGFRWSFLVGWLYWANWTLVTVVELLAAGSFLRYWMPSVPLWLLALGCALLIIVLNLFPVRYYGETEFWLAGLKVAAL
VVFILLGAGMWFGVIEGANGDPWARYATYDTWFPHGVGGMISALLVVVFSYGGAELIGVAVTEMKDADRVLPRVIKTTIW
RVIGFYVLPIAIICGIMPWNAVSAENSPFVQVLEATGISGAAHVMNAILLIAVLSAANTGVYATSRLLFSMAEQGEASRR
LLRTTRHGVPLYGMGMVALCIAAGVVGAYLAPGRIIGELMTIPGFTVLIVWMMIGAAQLKLRPNYDTNPFFRVKGFPYTT
SIAVVSLGAIWVSFLFQREHRIGSVLCLMILAILAMYGSIKEKQRRLPEQNIDEQSA

Sequences:

>Translated_457_residues
MEHSRPSLQKGLLPRHVQLMALGGMIGTGIFKGSADTIHIAGPSVVLTYLLGGALLFLIMAALAEMALAYPGENVQHLIR
RAFGFRWSFLVGWLYWANWTLVTVVELLAAGSFLRYWMPSVPLWLLALGCALLIIVLNLFPVRYYGETEFWLAGLKVAAL
VVFILLGAGMWFGVIEGANGDPWARYATYDTWFPHGVGGMISALLVVVFSYGGAELIGVAVTEMKDADRVLPRVIKTTIW
RVIGFYVLPIAIICGIMPWNAVSAENSPFVQVLEATGISGAAHVMNAILLIAVLSAANTGVYATSRLLFSMAEQGEASRR
LLRTTRHGVPLYGMGMVALCIAAGVVGAYLAPGRIIGELMTIPGFTVLIVWMMIGAAQLKLRPNYDTNPFFRVKGFPYTT
SIAVVSLGAIWVSFLFQREHRIGSVLCLMILAILAMYGSIKEKQRRLPEQNIDEQSA
>Mature_457_residues
MEHSRPSLQKGLLPRHVQLMALGGMIGTGIFKGSADTIHIAGPSVVLTYLLGGALLFLIMAALAEMALAYPGENVQHLIR
RAFGFRWSFLVGWLYWANWTLVTVVELLAAGSFLRYWMPSVPLWLLALGCALLIIVLNLFPVRYYGETEFWLAGLKVAAL
VVFILLGAGMWFGVIEGANGDPWARYATYDTWFPHGVGGMISALLVVVFSYGGAELIGVAVTEMKDADRVLPRVIKTTIW
RVIGFYVLPIAIICGIMPWNAVSAENSPFVQVLEATGISGAAHVMNAILLIAVLSAANTGVYATSRLLFSMAEQGEASRR
LLRTTRHGVPLYGMGMVALCIAAGVVGAYLAPGRIIGELMTIPGFTVLIVWMMIGAAQLKLRPNYDTNPFFRVKGFPYTT
SIAVVSLGAIWVSFLFQREHRIGSVLCLMILAILAMYGSIKEKQRRLPEQNIDEQSA

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786789, Length=451, Percent_Identity=34.3680709534368, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI1786302, Length=385, Percent_Identity=36.6233766233766, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1790653, Length=403, Percent_Identity=33.0024813895782, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI48994972, Length=466, Percent_Identity=33.0472103004292, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI87081708, Length=462, Percent_Identity=31.3852813852814, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1788480, Length=439, Percent_Identity=33.9407744874715, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI87081915, Length=463, Percent_Identity=29.5896328293737, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1786602, Length=383, Percent_Identity=34.7258485639687, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1789017, Length=391, Percent_Identity=35.0383631713555, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87082250, Length=410, Percent_Identity=24.1463414634146, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=370, Percent_Identity=23.7837837837838, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=342, Percent_Identity=23.9766081871345, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324924, Length=448, Percent_Identity=29.9107142857143, Blast_Score=186, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320772, Length=403, Percent_Identity=29.5285359801489, Blast_Score=182, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6324061, Length=494, Percent_Identity=27.5303643724696, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319824, Length=404, Percent_Identity=29.2079207920792, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324059, Length=407, Percent_Identity=29.97542997543, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6321629, Length=398, Percent_Identity=28.391959798995, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6319543, Length=403, Percent_Identity=28.0397022332506, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6324990, Length=410, Percent_Identity=27.8048780487805, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6320717, Length=406, Percent_Identity=26.1083743842365, Blast_Score=153, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6324553, Length=396, Percent_Identity=29.7979797979798, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322892, Length=389, Percent_Identity=29.305912596401, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320251, Length=399, Percent_Identity=27.5689223057644, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319542, Length=407, Percent_Identity=28.992628992629, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6322967, Length=400, Percent_Identity=30.25, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6321053, Length=397, Percent_Identity=28.9672544080605, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319608, Length=439, Percent_Identity=25.9681093394077, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324981, Length=398, Percent_Identity=29.6482412060301, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320364, Length=461, Percent_Identity=23.8611713665944, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49886; Mature: 49886

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHSRPSLQKGLLPRHVQLMALGGMIGTGIFKGSADTIHIAGPSVVLTYLLGGALLFLIM
CCCCCCCHHHCCCHHHHHHHHHHHHHHHCEECCCCCEEEECCHHHHHHHHHHHHHHHHHH
AALAEMALAYPGENVQHLIRRAFGFRWSFLVGWLYWANWTLVTVVELLAAGSFLRYWMPS
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
VPLWLLALGCALLIIVLNLFPVRYYGETEFWLAGLKVAALVVFILLGAGMWFGVIEGANG
HHHHHHHHHHHHHHHHHHHHCHHEECCHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCC
DPWARYATYDTWFPHGVGGMISALLVVVFSYGGAELIGVAVTEMKDADRVLPRVIKTTIW
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVIGFYVLPIAIICGIMPWNAVSAENSPFVQVLEATGISGAAHVMNAILLIAVLSAANTG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
VYATSRLLFSMAEQGEASRRLLRTTRHGVPLYGMGMVALCIAAGVVGAYLAPGRIIGELM
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TIPGFTVLIVWMMIGAAQLKLRPNYDTNPFFRVKGFPYTTSIAVVSLGAIWVSFLFQREH
HCCCHHHHHHHHHHCCHHEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RIGSVLCLMILAILAMYGSIKEKQRRLPEQNIDEQSA
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEHSRPSLQKGLLPRHVQLMALGGMIGTGIFKGSADTIHIAGPSVVLTYLLGGALLFLIM
CCCCCCCHHHCCCHHHHHHHHHHHHHHHCEECCCCCEEEECCHHHHHHHHHHHHHHHHHH
AALAEMALAYPGENVQHLIRRAFGFRWSFLVGWLYWANWTLVTVVELLAAGSFLRYWMPS
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
VPLWLLALGCALLIIVLNLFPVRYYGETEFWLAGLKVAALVVFILLGAGMWFGVIEGANG
HHHHHHHHHHHHHHHHHHHHCHHEECCHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCC
DPWARYATYDTWFPHGVGGMISALLVVVFSYGGAELIGVAVTEMKDADRVLPRVIKTTIW
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVIGFYVLPIAIICGIMPWNAVSAENSPFVQVLEATGISGAAHVMNAILLIAVLSAANTG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
VYATSRLLFSMAEQGEASRRLLRTTRHGVPLYGMGMVALCIAAGVVGAYLAPGRIIGELM
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TIPGFTVLIVWMMIGAAQLKLRPNYDTNPFFRVKGFPYTTSIAVVSLGAIWVSFLFQREH
HCCCHHHHHHHHHHCCHHEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RIGSVLCLMILAILAMYGSIKEKQRRLPEQNIDEQSA
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]