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The map label for this gene is yprA [H]

Identifier: 138895050

GI number: 138895050

Start: 1475053

End: 1477365

Strand: Direct

Name: yprA [H]

Synonym: GTNG_1388

Alternate gene names: 138895050

Gene position: 1475053-1477365 (Clockwise)

Preceding gene: 138895049

Following gene: 138895051

Centisome position: 41.55

GC content: 53.61

Gene sequence:

>2313_bases
GTGATTTGCAACGTGAAAAAACAGACGCTTTCTGAATGGATCGAACAGCTCCGCCAAGATCCGAATGTCGTGTATTGGCA
CGAAATCGAACCAAAAGAAGCTGATACGGTCCCGTTTCCAGCCGAGATCGACGCGCGGCTGCGCGCGGCGCTTGAAGCGC
GCGGCATCGCCTCGCTTTATACGCACCAAGCGGCGGCGTATGAGGCAGTGCAAAGCGGGCGGAATGTTGTTGCTGTGACA
CCGACTGCTTCCGGAAAAACGCTTTGTTACAATTTGCCTGTGCTTCAGGCGATCGCTAAAGCGCCCGAAAGCCGCGCCCT
CTACTTATTTCCAACCAAAGCGCTCGCTCAAGACCAAAAAAATGAATTGAACGAAATAATCGCTGAGATGGACGTGCCGA
TTTATAGCTATACATATGACGGCGATACAGCACCGGCGTTGCGGCAAAAAATCCGCCAAGCCGGCCATATTGTAATCACG
AATCCGGATATGCTTCATACGGCGATTTTGCCGCATCATACGAAATGGATTTCACTGTTTGAACAGTTGCGTTATGTCGT
CATCGATGAACTGCATACATATCGAGGGGTGTTTGGCAGCCATGTGGCAAACGTCATCCGCCGCTTAAAACGAATATGTG
CGTTTTACGGCAGCCAGCCGACATTTATTTGTACGTCAGCAACGATTGCTAATCCGCAAGAGCTGGCTGAGCGGTTGACC
GGCGAGCCGATGACGCTCATTGACAACAACGGGGCACCGCGCGGGCGGAAACATATCGTATTTTACAACCCGCCGGTCGT
CGAACGGACGATGAACGTTCGCCAAAGCGCAACAAAAACAGCGGTGGAACTAGCACGGCAACTGCTTGTCAATCGCATCC
CGACGATTGTTTTTGCCCGCAGCCGCGTCCGTACCGAACTCATTTTGAGCCATTTGCAGGCGGCGGTGAAGGAACGGATT
GGCGAAACGACGATTCGAGGCTACCGCGGTGGCTATTTGCCGAATGAACGGCGTGCCATTGAAAACGGGCTACGCAATGG
GGACATTATCGGCGTGGTCAGTACGAACGCACTCGAGCTTGGCGTCGATATCGGCCAGCTGCAGGCGTGCATTTTGACCG
GCTATCCGGGAACGATCGCCAGCACGTGGCAGCAAGCCGGGCGTGCCGGACGGCGTCATGGCGACTCGCTTGTGATTATG
GTTGCCAGCTCGAGTCCGCTTGACCAATATATCGTCTCCCATCCGGAATACTTTTTCGCCCGTTCTCCGGAGACGGCCCG
CATCAATCCAGACAATATGCTCATTTTGGTCGATCATTTGAAATGTGCCGCATATGAGCTTCCGTTCCGGCGCGGCGAGA
CGTTTGGCGGCATCGACGTTGAAGACGTGCTCGACTTTCTGGTCGACCAAGGAGTGCTTCATGAGCGGGCCGGGCGTTGG
CATTGGATGAGTGATGCCTTTCCGGCGCAAAACATTAGCTTGCGCTCGGCGGCCCAGGAAAATGTGGTAATCATCGATAT
TTCAAATATAGCGCGCCACCGCGTCATCGGCGAAATGGACCGCTTCAGCGCCATGACGCTGCTCCATGAAGAAGCGATTT
ATTTGCACGAAGGGACGCAATATCAGGTTGAAAAGCTTGACTGGGAGGAGAAAAAAGCGTACGTCCGCCAAGTCGATGTC
GAGTATTTCACCGATGCCAATTTGGCTGTACAGCTTGACGTGCTGTCTAATGACCGGAGCGAAGAGCGCGGGGCGATGGC
GGTGCACTACGGTGATGTGTCCGTCCGGGCGATGGCGACGATTTTTAAAAAATTGAAACTGTCAACGTTTGAAAATATCG
GCTCGGGACCGATTCGCCTTCCGGAAGAAACGCTTCATACGTCGGCAGCATGGTTTGAATGGAAAGAAGTTCCATCGGAA
TTTTCCCCAGCATTATTCGAACATTTGCTTGTCGGCCTCGCCAACGTGCTCAGCCATCTTGTTCCGATCTTTGTCATGTG
CGACCGCTCGGACGTTCACGTTGTTCCACAGCTGAAGGCGCCGCACTCCGGACGGCCGACGATTTTTCTTTACGACCGCT
ATCCGGGCGGTGTCGGCTTATCGGAAGCTGTATTTGAACGGTATGAAGAAATACTCGAGAACGTAAAGGAATGGGTGAAG
CGCTGTCCGTGCAGCGATGGTTGCCCGTCATGCATCGGCGTTTCCGACACAGGGGGGCAGCCGGTGAAGCGTGAGCTTAT
TCAGTTTTTAGATGAACAGCTTGCAGTATGGAGCGGCTCGCTTGTTTCGCACCGCAGTTGTGAAGAAAACTGA

Upstream 100 bases:

>100_bases
GGGCATGGGGAGAGCAGTTTGCTTTGGCTGCCGCTGTTTTTTGCCATGCAAATAGAAGGAGTAGGCTATTCTCTCTTATT
TCTTGTAAAATAGAAACGAG

Downstream 100 bases:

>100_bases
GTGGCGTCGCCAAGCTTGAGTGCCAGCGGGCGGGGAAACTAAAGCGGCTTTCTTGAGCGTTCGCGCGCTAAATTTATAGG
AGGAAGAGAGCGAGCGGAAA

Product: ATP-dependent RNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 770; Mature: 770

Protein sequence:

>770_residues
MICNVKKQTLSEWIEQLRQDPNVVYWHEIEPKEADTVPFPAEIDARLRAALEARGIASLYTHQAAAYEAVQSGRNVVAVT
PTASGKTLCYNLPVLQAIAKAPESRALYLFPTKALAQDQKNELNEIIAEMDVPIYSYTYDGDTAPALRQKIRQAGHIVIT
NPDMLHTAILPHHTKWISLFEQLRYVVIDELHTYRGVFGSHVANVIRRLKRICAFYGSQPTFICTSATIANPQELAERLT
GEPMTLIDNNGAPRGRKHIVFYNPPVVERTMNVRQSATKTAVELARQLLVNRIPTIVFARSRVRTELILSHLQAAVKERI
GETTIRGYRGGYLPNERRAIENGLRNGDIIGVVSTNALELGVDIGQLQACILTGYPGTIASTWQQAGRAGRRHGDSLVIM
VASSSPLDQYIVSHPEYFFARSPETARINPDNMLILVDHLKCAAYELPFRRGETFGGIDVEDVLDFLVDQGVLHERAGRW
HWMSDAFPAQNISLRSAAQENVVIIDISNIARHRVIGEMDRFSAMTLLHEEAIYLHEGTQYQVEKLDWEEKKAYVRQVDV
EYFTDANLAVQLDVLSNDRSEERGAMAVHYGDVSVRAMATIFKKLKLSTFENIGSGPIRLPEETLHTSAAWFEWKEVPSE
FSPALFEHLLVGLANVLSHLVPIFVMCDRSDVHVVPQLKAPHSGRPTIFLYDRYPGGVGLSEAVFERYEEILENVKEWVK
RCPCSDGCPSCIGVSDTGGQPVKRELIQFLDEQLAVWSGSLVSHRSCEEN

Sequences:

>Translated_770_residues
MICNVKKQTLSEWIEQLRQDPNVVYWHEIEPKEADTVPFPAEIDARLRAALEARGIASLYTHQAAAYEAVQSGRNVVAVT
PTASGKTLCYNLPVLQAIAKAPESRALYLFPTKALAQDQKNELNEIIAEMDVPIYSYTYDGDTAPALRQKIRQAGHIVIT
NPDMLHTAILPHHTKWISLFEQLRYVVIDELHTYRGVFGSHVANVIRRLKRICAFYGSQPTFICTSATIANPQELAERLT
GEPMTLIDNNGAPRGRKHIVFYNPPVVERTMNVRQSATKTAVELARQLLVNRIPTIVFARSRVRTELILSHLQAAVKERI
GETTIRGYRGGYLPNERRAIENGLRNGDIIGVVSTNALELGVDIGQLQACILTGYPGTIASTWQQAGRAGRRHGDSLVIM
VASSSPLDQYIVSHPEYFFARSPETARINPDNMLILVDHLKCAAYELPFRRGETFGGIDVEDVLDFLVDQGVLHERAGRW
HWMSDAFPAQNISLRSAAQENVVIIDISNIARHRVIGEMDRFSAMTLLHEEAIYLHEGTQYQVEKLDWEEKKAYVRQVDV
EYFTDANLAVQLDVLSNDRSEERGAMAVHYGDVSVRAMATIFKKLKLSTFENIGSGPIRLPEETLHTSAAWFEWKEVPSE
FSPALFEHLLVGLANVLSHLVPIFVMCDRSDVHVVPQLKAPHSGRPTIFLYDRYPGGVGLSEAVFERYEEILENVKEWVK
RCPCSDGCPSCIGVSDTGGQPVKRELIQFLDEQLAVWSGSLVSHRSCEEN
>Mature_770_residues
MICNVKKQTLSEWIEQLRQDPNVVYWHEIEPKEADTVPFPAEIDARLRAALEARGIASLYTHQAAAYEAVQSGRNVVAVT
PTASGKTLCYNLPVLQAIAKAPESRALYLFPTKALAQDQKNELNEIIAEMDVPIYSYTYDGDTAPALRQKIRQAGHIVIT
NPDMLHTAILPHHTKWISLFEQLRYVVIDELHTYRGVFGSHVANVIRRLKRICAFYGSQPTFICTSATIANPQELAERLT
GEPMTLIDNNGAPRGRKHIVFYNPPVVERTMNVRQSATKTAVELARQLLVNRIPTIVFARSRVRTELILSHLQAAVKERI
GETTIRGYRGGYLPNERRAIENGLRNGDIIGVVSTNALELGVDIGQLQACILTGYPGTIASTWQQAGRAGRRHGDSLVIM
VASSSPLDQYIVSHPEYFFARSPETARINPDNMLILVDHLKCAAYELPFRRGETFGGIDVEDVLDFLVDQGVLHERAGRW
HWMSDAFPAQNISLRSAAQENVVIIDISNIARHRVIGEMDRFSAMTLLHEEAIYLHEGTQYQVEKLDWEEKKAYVRQVDV
EYFTDANLAVQLDVLSNDRSEERGAMAVHYGDVSVRAMATIFKKLKLSTFENIGSGPIRLPEETLHTSAAWFEWKEVPSE
FSPALFEHLLVGLANVLSHLVPIFVMCDRSDVHVVPQLKAPHSGRPTIFLYDRYPGGVGLSEAVFERYEEILENVKEWVK
RCPCSDGCPSCIGVSDTGGQPVKRELIQFLDEQLAVWSGSLVSHRSCEEN

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI284005309, Length=396, Percent_Identity=25.2525252525253, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI188035877, Length=323, Percent_Identity=25.3869969040248, Blast_Score=67, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320497, Length=716, Percent_Identity=34.4972067039106, Blast_Score=401, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI9755332, Length=385, Percent_Identity=23.6363636363636, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 86371; Mature: 86371

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICNVKKQTLSEWIEQLRQDPNVVYWHEIEPKEADTVPFPAEIDARLRAALEARGIASLY
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
THQAAAYEAVQSGRNVVAVTPTASGKTLCYNLPVLQAIAKAPESRALYLFPTKALAQDQK
HHHHHHHHHHHCCCCEEEEECCCCCCEEEEECHHHHHHHCCCCCCEEEEECCHHHHHHHH
NELNEIIAEMDVPIYSYTYDGDTAPALRQKIRQAGHIVITNPDMLHTAILPHHTKWISLF
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHCCCHHHHHHHH
EQLRYVVIDELHTYRGVFGSHVANVIRRLKRICAFYGSQPTFICTSATIANPQELAERLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHC
GEPMTLIDNNGAPRGRKHIVFYNPPVVERTMNVRQSATKTAVELARQLLVNRIPTIVFAR
CCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SRVRTELILSHLQAAVKERIGETTIRGYRGGYLPNERRAIENGLRNGDIIGVVSTNALEL
HHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCEEE
GVDIGQLQACILTGYPGTIASTWQQAGRAGRRHGDSLVIMVASSSPLDQYIVSHPEYFFA
CCCHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCEEE
RSPETARINPDNMLILVDHLKCAAYELPFRRGETFGGIDVEDVLDFLVDQGVLHERAGRW
CCCCCCEECCCCEEEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCE
HWMSDAFPAQNISLRSAAQENVVIIDISNIARHRVIGEMDRFSAMTLLHEEAIYLHEGTQ
EECCCCCCCCCCCHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCC
YQVEKLDWEEKKAYVRQVDVEYFTDANLAVQLDVLSNDRSEERGAMAVHYGDVSVRAMAT
EEHHHCCHHHHHHHHHHHCHHHEECCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
IFKKLKLSTFENIGSGPIRLPEETLHTSAAWFEWKEVPSEFSPALFEHLLVGLANVLSHL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VPIFVMCDRSDVHVVPQLKAPHSGRPTIFLYDRYPGGVGLSEAVFERYEEILENVKEWVK
HHEEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
RCPCSDGCPSCIGVSDTGGQPVKRELIQFLDEQLAVWSGSLVSHRSCEEN
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MICNVKKQTLSEWIEQLRQDPNVVYWHEIEPKEADTVPFPAEIDARLRAALEARGIASLY
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
THQAAAYEAVQSGRNVVAVTPTASGKTLCYNLPVLQAIAKAPESRALYLFPTKALAQDQK
HHHHHHHHHHHCCCCEEEEECCCCCCEEEEECHHHHHHHCCCCCCEEEEECCHHHHHHHH
NELNEIIAEMDVPIYSYTYDGDTAPALRQKIRQAGHIVITNPDMLHTAILPHHTKWISLF
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHCCCHHHHHHHH
EQLRYVVIDELHTYRGVFGSHVANVIRRLKRICAFYGSQPTFICTSATIANPQELAERLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHC
GEPMTLIDNNGAPRGRKHIVFYNPPVVERTMNVRQSATKTAVELARQLLVNRIPTIVFAR
CCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SRVRTELILSHLQAAVKERIGETTIRGYRGGYLPNERRAIENGLRNGDIIGVVSTNALEL
HHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCEEE
GVDIGQLQACILTGYPGTIASTWQQAGRAGRRHGDSLVIMVASSSPLDQYIVSHPEYFFA
CCCHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCEEE
RSPETARINPDNMLILVDHLKCAAYELPFRRGETFGGIDVEDVLDFLVDQGVLHERAGRW
CCCCCCEECCCCEEEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCE
HWMSDAFPAQNISLRSAAQENVVIIDISNIARHRVIGEMDRFSAMTLLHEEAIYLHEGTQ
EECCCCCCCCCCCHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCC
YQVEKLDWEEKKAYVRQVDVEYFTDANLAVQLDVLSNDRSEERGAMAVHYGDVSVRAMAT
EEHHHCCHHHHHHHHHHHCHHHEECCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
IFKKLKLSTFENIGSGPIRLPEETLHTSAAWFEWKEVPSEFSPALFEHLLVGLANVLSHL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VPIFVMCDRSDVHVVPQLKAPHSGRPTIFLYDRYPGGVGLSEAVFERYEEILENVKEWVK
HHEEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
RCPCSDGCPSCIGVSDTGGQPVKRELIQFLDEQLAVWSGSLVSHRSCEEN
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]