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The map label for this gene is cysI [H]

Identifier: 138894932

GI number: 138894932

Start: 1340346

End: 1342067

Strand: Direct

Name: cysI [H]

Synonym: GTNG_1270

Alternate gene names: 138894932

Gene position: 1340346-1342067 (Clockwise)

Preceding gene: 138894931

Following gene: 138894933

Centisome position: 37.75

GC content: 54.3

Gene sequence:

>1722_bases
ATGGCGAAAGTCGTGTTAAAAGCGCCGGATGGACCGCCAAGCGATGTCGAGCGCATTAAACGGGAAAGCCGTTATTTGCG
CGGCACGCTCGCCGAAACGATGGAAGACCCGATCAGCGCGGGCATTCCGGACGATGACAACCGGCTGATGAAGTTCCATG
GCAGCTACTTGCAAGACGACCGTGACGTGCGTACCGAGCGGCAAAAACAAAAGCTCGAGCCGGCATACCAATTCATGATT
CGCGTTCGCACACCAGGTGGGGTAGCAACGCCGGAGCAATGGCTTGTCATGGACGAAATCGCCCGCAAATACGCAAACGG
TACGTTGAAGTTAACGACGCGCCAAGCGTTCCAATTGCACGGCGTCTTGAAATGGAACGTGAAAAAAACGATGCAAGCCA
TTAACGGCGCGCTCATGACAACGCTCGCCGCCTGCGGCGACGTCAACCGGAACGTCATGTGCAATCCGAACCCATACCAA
TCGGAAGTGCATGCGGAAGTGTACGAATGGGCGAAACTGTTAAGCGACCATTTGTTGCCGAAGACACGGGCGTATTATGA
AATTTGGTTGGATGACGAAAAAGTGGCCGGCACGCCGCAAGTCGACGGTGAGGAAGAACCGATTTACGGCCCGACGTACT
TGCCGCGGAAATTTAAAATCGGAATCGCTGTCCCGCCGTCCAACGACGTCGACGTATTCTCGCAAGATATCGGGTTGATC
GCCATCGTGGAAGACGGCAAACTCGCCGGTTTTAACGTCGCCATCGGCGGCGGCATGGGGATGACCCACGGCGACAAAAC
GACGTACCCACAGCTCGCTAAAGTGATCGGTTTCTGCACGCCGGATCAAGTTGTTGAAGTGGCAGAAAAAATTATGACGG
TTCAACGCGACTATGGCAACCGCTCGGTGCGTAAAAACGCCCGCTTCAAATACACGATCGACCGGCTTGGCCTTGAAGTA
GTGAAAGAGGAAATTGAACGCCGTCTCGGCTGGAAGCTCGGCGAAGCGCGCCCGTACCATTTCGAGCATAATGGCGACCG
TTACGGCTGGGTTGAAGGCGTCAATGGAACATGGCATTTTACGCTTTATGTTGAAGGCGGCCGCGTCAAAGACGATGACG
ATTACAAGCTGATGACCGGCCTGCGCGAAATTGCCAAAGTCCATACCGGCGATTTCCGACTGACGGCGAACCAAAACTTA
GTGATCGCCAATGTCACAAGCGAGAAAAAAGCAGAAATTGAAGCGCTAATCGCTAAGTATGGCTTAACCGATGGCAAACG
GTACACCGCTTTGCGCCGCAACTCGCTCGCCTGTGTCGCGCTGCCGACATGCGGCCTGGCGATGGCGGAAGCGGAGCGGT
ATTTGCCGAAACTGCTTGATAAAATCGAGGAAATCATCGATGAAAACGGCTTGCGCGACGAAGAAATCACGATCCGCATG
ACGGGCTGTCCGAACGGTTGCGCCCGCCACGTGCTCGCCGAAATCGCCTTCGTCGGCAAAGCTGTCGGCAAATACAACAT
GTACCTCGGCGCCGCATTCAATGGTACGCGCCTTGGCAAACTGTACCGAGAAAATATCGGTGAAGAAGAAATTTTGCGCG
AACTGCGCGTCCTTTTGGCCCGCTATGCAAAAGAACGACTTGACGGTGAACACTTCGGCGATTTTGTCATCCGCGCCGGC
ATCGTCAAAGAAGTCACAGACGGAACGAATTTCCACGATTAA

Upstream 100 bases:

>100_bases
TATGAGCCGCGAGCAAGCGGAAGCTTATTTGACCGAAATGCAAAAACAAAAACGGTACCAACGTGACGTCTATTAATCTC
AAAGAAGGAGTGGAATCGAA

Downstream 100 bases:

>100_bases
GATGACACGGATTCATCCTGACCGGCCTCCCTTGTTTTGAGGAGGCCGGTTTTTTGTCGTTAACCCAGATGATGATTTGT
CGCTTTCTCTGTCAAGATGG

Product: sulfite reductase subunit beta

Products: NA

Alternate protein names: SiR-HP; SiRHP [H]

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MAKVVLKAPDGPPSDVERIKRESRYLRGTLAETMEDPISAGIPDDDNRLMKFHGSYLQDDRDVRTERQKQKLEPAYQFMI
RVRTPGGVATPEQWLVMDEIARKYANGTLKLTTRQAFQLHGVLKWNVKKTMQAINGALMTTLAACGDVNRNVMCNPNPYQ
SEVHAEVYEWAKLLSDHLLPKTRAYYEIWLDDEKVAGTPQVDGEEEPIYGPTYLPRKFKIGIAVPPSNDVDVFSQDIGLI
AIVEDGKLAGFNVAIGGGMGMTHGDKTTYPQLAKVIGFCTPDQVVEVAEKIMTVQRDYGNRSVRKNARFKYTIDRLGLEV
VKEEIERRLGWKLGEARPYHFEHNGDRYGWVEGVNGTWHFTLYVEGGRVKDDDDYKLMTGLREIAKVHTGDFRLTANQNL
VIANVTSEKKAEIEALIAKYGLTDGKRYTALRRNSLACVALPTCGLAMAEAERYLPKLLDKIEEIIDENGLRDEEITIRM
TGCPNGCARHVLAEIAFVGKAVGKYNMYLGAAFNGTRLGKLYRENIGEEEILRELRVLLARYAKERLDGEHFGDFVIRAG
IVKEVTDGTNFHD

Sequences:

>Translated_573_residues
MAKVVLKAPDGPPSDVERIKRESRYLRGTLAETMEDPISAGIPDDDNRLMKFHGSYLQDDRDVRTERQKQKLEPAYQFMI
RVRTPGGVATPEQWLVMDEIARKYANGTLKLTTRQAFQLHGVLKWNVKKTMQAINGALMTTLAACGDVNRNVMCNPNPYQ
SEVHAEVYEWAKLLSDHLLPKTRAYYEIWLDDEKVAGTPQVDGEEEPIYGPTYLPRKFKIGIAVPPSNDVDVFSQDIGLI
AIVEDGKLAGFNVAIGGGMGMTHGDKTTYPQLAKVIGFCTPDQVVEVAEKIMTVQRDYGNRSVRKNARFKYTIDRLGLEV
VKEEIERRLGWKLGEARPYHFEHNGDRYGWVEGVNGTWHFTLYVEGGRVKDDDDYKLMTGLREIAKVHTGDFRLTANQNL
VIANVTSEKKAEIEALIAKYGLTDGKRYTALRRNSLACVALPTCGLAMAEAERYLPKLLDKIEEIIDENGLRDEEITIRM
TGCPNGCARHVLAEIAFVGKAVGKYNMYLGAAFNGTRLGKLYRENIGEEEILRELRVLLARYAKERLDGEHFGDFVIRAG
IVKEVTDGTNFHD
>Mature_572_residues
AKVVLKAPDGPPSDVERIKRESRYLRGTLAETMEDPISAGIPDDDNRLMKFHGSYLQDDRDVRTERQKQKLEPAYQFMIR
VRTPGGVATPEQWLVMDEIARKYANGTLKLTTRQAFQLHGVLKWNVKKTMQAINGALMTTLAACGDVNRNVMCNPNPYQS
EVHAEVYEWAKLLSDHLLPKTRAYYEIWLDDEKVAGTPQVDGEEEPIYGPTYLPRKFKIGIAVPPSNDVDVFSQDIGLIA
IVEDGKLAGFNVAIGGGMGMTHGDKTTYPQLAKVIGFCTPDQVVEVAEKIMTVQRDYGNRSVRKNARFKYTIDRLGLEVV
KEEIERRLGWKLGEARPYHFEHNGDRYGWVEGVNGTWHFTLYVEGGRVKDDDDYKLMTGLREIAKVHTGDFRLTANQNLV
IANVTSEKKAEIEALIAKYGLTDGKRYTALRRNSLACVALPTCGLAMAEAERYLPKLLDKIEEIIDENGLRDEEITIRMT
GCPNGCARHVLAEIAFVGKAVGKYNMYLGAAFNGTRLGKLYRENIGEEEILRELRVLLARYAKERLDGEHFGDFVIRAGI
VKEVTDGTNFHD

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate [H]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=559, Percent_Identity=51.6994633273703, Blast_Score=611, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6322597, Length=592, Percent_Identity=49.3243243243243, Blast_Score=592, Evalue=1e-170,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011786
- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 64541; Mature: 64409

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00365 NIR_SIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVVLKAPDGPPSDVERIKRESRYLRGTLAETMEDPISAGIPDDDNRLMKFHGSYLQDD
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHCCC
RDVRTERQKQKLEPAYQFMIRVRTPGGVATPEQWLVMDEIARKYANGTLKLTTRQAFQLH
HHHHHHHHHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHH
GVLKWNVKKTMQAINGALMTTLAACGDVNRNVMCNPNPYQSEVHAEVYEWAKLLSDHLLP
CEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCC
KTRAYYEIWLDDEKVAGTPQVDGEEEPIYGPTYLPRKFKIGIAVPPSNDVDVFSQDIGLI
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCEE
AIVEDGKLAGFNVAIGGGMGMTHGDKTTYPQLAKVIGFCTPDQVVEVAEKIMTVQRDYGN
EEEECCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RSVRKNARFKYTIDRLGLEVVKEEIERRLGWKLGEARPYHFEHNGDRYGWVEGVNGTWHF
CCHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEECCCCEEEE
TLYVEGGRVKDDDDYKLMTGLREIAKVHTGDFRLTANQNLVIANVTSEKKAEIEALIAKY
EEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHH
GLTDGKRYTALRRNSLACVALPTCGLAMAEAERYLPKLLDKIEEIIDENGLRDEEITIRM
CCCCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
TGCPNGCARHVLAEIAFVGKAVGKYNMYLGAAFNGTRLGKLYRENIGEEEILRELRVLLA
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHH
RYAKERLDGEHFGDFVIRAGIVKEVTDGTNFHD
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKVVLKAPDGPPSDVERIKRESRYLRGTLAETMEDPISAGIPDDDNRLMKFHGSYLQDD
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHCCC
RDVRTERQKQKLEPAYQFMIRVRTPGGVATPEQWLVMDEIARKYANGTLKLTTRQAFQLH
HHHHHHHHHHHCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHH
GVLKWNVKKTMQAINGALMTTLAACGDVNRNVMCNPNPYQSEVHAEVYEWAKLLSDHLLP
CEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCC
KTRAYYEIWLDDEKVAGTPQVDGEEEPIYGPTYLPRKFKIGIAVPPSNDVDVFSQDIGLI
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCCEE
AIVEDGKLAGFNVAIGGGMGMTHGDKTTYPQLAKVIGFCTPDQVVEVAEKIMTVQRDYGN
EEEECCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RSVRKNARFKYTIDRLGLEVVKEEIERRLGWKLGEARPYHFEHNGDRYGWVEGVNGTWHF
CCHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEECCCCEEEE
TLYVEGGRVKDDDDYKLMTGLREIAKVHTGDFRLTANQNLVIANVTSEKKAEIEALIAKY
EEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHH
GLTDGKRYTALRRNSLACVALPTCGLAMAEAERYLPKLLDKIEEIIDENGLRDEEITIRM
CCCCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
TGCPNGCARHVLAEIAFVGKAVGKYNMYLGAAFNGTRLGKLYRENIGEEEILRELRVLLA
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHH
RYAKERLDGEHFGDFVIRAGIVKEVTDGTNFHD
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA