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The map label for this gene is glnA [H]

Identifier: 138894846

GI number: 138894846

Start: 1252730

End: 1254064

Strand: Direct

Name: glnA [H]

Synonym: GTNG_1182

Alternate gene names: 138894846

Gene position: 1252730-1254064 (Clockwise)

Preceding gene: 138894845

Following gene: 138894848

Centisome position: 35.28

GC content: 50.34

Gene sequence:

>1335_bases
ATGGCAAAATATACGCGCGAAGACATTATGCGCATCGTCAAAGAAGAAAACGTCAAGTACATTCGCCTGCAATTCACCGA
TATTTTGGGTACGATCAAAAACGTCGAAATTCCGATCAGTCAGCTTGAGAAGGCGCTTAACAATAAAATGATGTTTGACG
GATCATCGATCGAGGGATTTGTCCGCATCGAAGAATCGGACATGTATTTATACCCTGATTTAGATACATTTGTCATCTTT
CCGTGGACCGCGGAAAAAGGGAAAGTCGCCCGCTTTATTTGTGACATTTACAATGCGGATGGCACACCGTTTGAAGGCTG
CCCGCGCTACAATTTAAAACGCGTGCTGAAGGAAATGGAAGCGCTCGGCTTTACGGCGTTCAACTTAGGGGCGGAGCCGG
AATTTTTCCTCTTTAAGCTCGATGAAAATGGGCGTCCGACGATGGAATTGAATGACCGCGGCGGCTATTTCGATTTGGCG
CCGACCGACTTGGGAGAAAACTGCCGGCGCGACATCGTGCTTGAGCTTGAGGAAATGGGGTTTGAAATTGAAGCATCGCA
CCACGAAGTCGCCCCGGGGCAGCACGAGATCGATTTTAAATATGCCCATGCTATCAAAGCATGCGACGACATTCAAACGT
TTAAGCTTGTCGTCAAGACGATCGCTCGCAAACATGGGCTGCACGCGACGTTTATGCCGAAGCCGATTTTCGGCATTAAC
GGTTCGGGAATGCACTGCAACTTATCGTTGTTCCGCAATAACGAAAACGCCTTTTTTGATCCGAACAGCGATTTGCAGTT
GAGCGATACGGCGCGGCAGTTTATCGCCGGTGTGCTGAAACATGCGCCAAACTTTACGGCGGTGACGAACCCGACGGTCA
ACTCGTATAAGCGGCTTGTTCCAGGCTATGAGGCTCCATGTTATGTTGCTTGGTCGGCGCACAACCGCAGCCCGCTCATC
CGTATTCCGTCTTCGCGCGGCATGAGCACCCGCATTGAAGTGCGCAGTGTCGACCCGGCGGCGAACCCGTACTTGGCGAT
GGCCGTGCTGTTGGCGGCTGGGCTTGACGGTATTCGCAACAAGCTCACTCCTCCGGCGCCGGTTGACCGAAATATTTACG
TCATGACAAAAGAAGAACGGCTTGAAGAAGGGATTGTCGATTTGCCGGCGACGCTGATCGAAGCGCTCGACAATTTAAAA
TCGGATGAGGTGATCATCCAAGCGCTTGGCAAACATTTATTCGAGCATTTCGTCGAAGCGAAAGAAATCGAGTGGGATAT
GTATCGGACAACGGTCCATCAATGGGAATTGAACCAATATATGGAGCTGTACTAA

Upstream 100 bases:

>100_bases
GGCCGGACGGTTTCAGCGCGCATCGCTTCGCCAAGGAGATCTCGCTCGCTTCTTTCATTAATGATGGAAAATGATTTCGG
AGCCGGGGAGGAGTTTAGAT

Downstream 100 bases:

>100_bases
TCATAAAAGCTGCCCCGACAAACGGGGCAGCTTTTGTTATGGAGCACGGCGCTGAACGGACTTTTAGTTGATCAGACGAT
AGACGCCAATCACTTTACCG

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAKYTREDIMRIVKEENVKYIRLQFTDILGTIKNVEIPISQLEKALNNKMMFDGSSIEGFVRIEESDMYLYPDLDTFVIF
PWTAEKGKVARFICDIYNADGTPFEGCPRYNLKRVLKEMEALGFTAFNLGAEPEFFLFKLDENGRPTMELNDRGGYFDLA
PTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAHAIKACDDIQTFKLVVKTIARKHGLHATFMPKPIFGIN
GSGMHCNLSLFRNNENAFFDPNSDLQLSDTARQFIAGVLKHAPNFTAVTNPTVNSYKRLVPGYEAPCYVAWSAHNRSPLI
RIPSSRGMSTRIEVRSVDPAANPYLAMAVLLAAGLDGIRNKLTPPAPVDRNIYVMTKEERLEEGIVDLPATLIEALDNLK
SDEVIIQALGKHLFEHFVEAKEIEWDMYRTTVHQWELNQYMELY

Sequences:

>Translated_444_residues
MAKYTREDIMRIVKEENVKYIRLQFTDILGTIKNVEIPISQLEKALNNKMMFDGSSIEGFVRIEESDMYLYPDLDTFVIF
PWTAEKGKVARFICDIYNADGTPFEGCPRYNLKRVLKEMEALGFTAFNLGAEPEFFLFKLDENGRPTMELNDRGGYFDLA
PTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAHAIKACDDIQTFKLVVKTIARKHGLHATFMPKPIFGIN
GSGMHCNLSLFRNNENAFFDPNSDLQLSDTARQFIAGVLKHAPNFTAVTNPTVNSYKRLVPGYEAPCYVAWSAHNRSPLI
RIPSSRGMSTRIEVRSVDPAANPYLAMAVLLAAGLDGIRNKLTPPAPVDRNIYVMTKEERLEEGIVDLPATLIEALDNLK
SDEVIIQALGKHLFEHFVEAKEIEWDMYRTTVHQWELNQYMELY
>Mature_443_residues
AKYTREDIMRIVKEENVKYIRLQFTDILGTIKNVEIPISQLEKALNNKMMFDGSSIEGFVRIEESDMYLYPDLDTFVIFP
WTAEKGKVARFICDIYNADGTPFEGCPRYNLKRVLKEMEALGFTAFNLGAEPEFFLFKLDENGRPTMELNDRGGYFDLAP
TDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAHAIKACDDIQTFKLVVKTIARKHGLHATFMPKPIFGING
SGMHCNLSLFRNNENAFFDPNSDLQLSDTARQFIAGVLKHAPNFTAVTNPTVNSYKRLVPGYEAPCYVAWSAHNRSPLIR
IPSSRGMSTRIEVRSVDPAANPYLAMAVLLAAGLDGIRNKLTPPAPVDRNIYVMTKEERLEEGIVDLPATLIEALDNLKS
DEVIIQALGKHLFEHFVEAKEIEWDMYRTTVHQWELNQYMELY

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=454, Percent_Identity=26.2114537444934, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1790301, Length=471, Percent_Identity=40.7643312101911, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI87081870, Length=462, Percent_Identity=27.0562770562771, Blast_Score=152, Evalue=6e-38,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50606; Mature: 50475

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYTREDIMRIVKEENVKYIRLQFTDILGTIKNVEIPISQLEKALNNKMMFDGSSIEGF
CCCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLYPDLDTFVIFPWTAEKGKVARFICDIYNADGTPFEGCPRYNLKRVLKEME
EEEECCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ALGFTAFNLGAEPEFFLFKLDENGRPTMELNDRGGYFDLAPTDLGENCRRDIVLELEEMG
HHCCEEEECCCCCCEEEEEECCCCCCCEEECCCCCEEECCCCCCCHHHHHHHEEEHHHCC
FEIEASHHEVAPGQHEIDFKYAHAIKACDDIQTFKLVVKTIARKHGLHATFMPKPIFGIN
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GSGMHCNLSLFRNNENAFFDPNSDLQLSDTARQFIAGVLKHAPNFTAVTNPTVNSYKRLV
CCCCEEEEEEEECCCCCEECCCCCCEEHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHC
PGYEAPCYVAWSAHNRSPLIRIPSSRGMSTRIEVRSVDPAANPYLAMAVLLAAGLDGIRN
CCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCHHHHHH
KLTPPAPVDRNIYVMTKEERLEEGIVDLPATLIEALDNLKSDEVIIQALGKHLFEHFVEA
CCCCCCCCCCCEEEEEHHHHHHCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KEIEWDMYRTTVHQWELNQYMELY
HHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKYTREDIMRIVKEENVKYIRLQFTDILGTIKNVEIPISQLEKALNNKMMFDGSSIEGF
CCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLYPDLDTFVIFPWTAEKGKVARFICDIYNADGTPFEGCPRYNLKRVLKEME
EEEECCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ALGFTAFNLGAEPEFFLFKLDENGRPTMELNDRGGYFDLAPTDLGENCRRDIVLELEEMG
HHCCEEEECCCCCCEEEEEECCCCCCCEEECCCCCEEECCCCCCCHHHHHHHEEEHHHCC
FEIEASHHEVAPGQHEIDFKYAHAIKACDDIQTFKLVVKTIARKHGLHATFMPKPIFGIN
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GSGMHCNLSLFRNNENAFFDPNSDLQLSDTARQFIAGVLKHAPNFTAVTNPTVNSYKRLV
CCCCEEEEEEEECCCCCEECCCCCCEEHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHC
PGYEAPCYVAWSAHNRSPLIRIPSSRGMSTRIEVRSVDPAANPYLAMAVLLAAGLDGIRN
CCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCHHHHHH
KLTPPAPVDRNIYVMTKEERLEEGIVDLPATLIEALDNLKSDEVIIQALGKHLFEHFVEA
CCCCCCCCCCCEEEEEHHHHHHCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KEIEWDMYRTTVHQWELNQYMELY
HHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2906311; 2565853; 9384377; 11719184 [H]