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The map label for this gene is ftsK [H]

Identifier: 138894801

GI number: 138894801

Start: 1197810

End: 1200149

Strand: Direct

Name: ftsK [H]

Synonym: GTNG_1135

Alternate gene names: 138894801

Gene position: 1197810-1200149 (Clockwise)

Preceding gene: 138894800

Following gene: 138894802

Centisome position: 33.74

GC content: 52.86

Gene sequence:

>2340_bases
ATGATGGCGAAACGAAAGCGAAAAAAAAGGGGAAAGCCGTCAAGGAAGCAGCCGTGGGCGGAGGCGATTCGCTTTGAACT
GATCGGCCTTGGGCTATTGACCGTTGCTGTTGTTGCGATGGCTCGCCTCGGGCTCGTCGGCGAAACGCTTGTGTTGATTA
GCCGCTTTTTTTTCGGCGAATGGTACATGCTATTAGTAGGCGGTTTATTCATTTTATCGTTCATCTTGATATGGAAACGG
GAGTGGCCGTCATGGGCGAGCCGACCGTTTGTTGGTGCTTCGATTATTGCTGCGGCGTTTTTGTTATTAAGCCATGGCAA
GTTGTTTGAACTCATGTCGCGGCGCGGTGAACTCGATCCAAGCGTTATTCGCACGACATGGGAACTGTTTTGGAACGAAG
CAAACGGCAAGGAGACCGCTATCGATTTAGGAGGCGGGATGGTCGGCGCGTTGTTGTTTGCCGCCAGCTATCAGCTGTTT
GATGCGCTCGGGACGAAATGGATTTGCTTCATTTTGTTCGTCGTCGGCTTCATCGTGCTGACTGGAAAATCGTTGCGTGA
GACGGCTGGCAGACTGATCGTCTTAGTAGCAACGTTTCTGCGCCAAGAATGGTTAGCGTTTGTTGAGGATATGAAGCAAT
GGGTGACGGGACGAAAAAGGCGGGCTAATAACGGACGGAAACGACGCAAGCTGCAGGACAAGGCGGCTGCCCAGCAGGAA
GATGAGCCTGCCGAAGCCGGCACCGCTGAACCGGAGGACGAGCTCCTTTCCCCACCGCCGATCATATCCGATTTTGCCGC
TGTCCGGTCGGCAGTCGAGCTCGAAGAAGAAAAGCAGCCGCCAACTGAAGGCGATGACGGCGGAAACGGGGATGCATCGA
CGCCACCGTTGGCGTTTTCCGAGCATGAAAACACCAACTATGATTTGCCGCCGCTTGAACTTCTTCGCCTGCCGAAACCG
GCCGGGCAATCGGCCGATCATGCCAACATTTACGCCAATGCGCGCAAATTAGAGAAAACGTTCCAAAGCTTCGGTGTTAA
GGCGAAAGTGACGCAAGTGCATCTTGGCCCGGCCGTGACGAAATACGAAGTATACCCAGATGTCGGGGTGAAAGTGAGTA
AAATCGTCAACTTAAGCGATGATCTGGCGCTCGCTCTAGCGGCGAAAGATATTCGCATTGAAGCACCGATTCCCGGCAAA
TCTGCGATCGGTATTGAGGTGCCGAACGAAGAAATCGCCACCGTGTCGCTGCGCGAAGTGTTGGAAGCCGTCGAACATAC
GCGGCCTGAGGCCAAGCTCTTAATCCCGCTTGGACGCGACATTTCCGGAGAAGTCGTCGCCGCCGAATTGAACAAAATGC
CGCATTTATTGATCGCTGGCGCCACTGGCAGCGGCAAAAGCGTCTGCATTAACGGCATTATCGTTAGCCTGCTTATGCGC
ACGAAGCCACATGAGGTCAAGTTGATGATGATTGACCCGAAAATGGTCGAGTTAAGCGTGTATAATGGCATCCCCCATTT
GTTGACGCCGGTTGTCACCGATGCGAAAAAAGCGGCCCAGGCGCTGAAAAAAGTTGTCCAAGAAATGGAGCGGCGCTATG
AGCTGTTTTCCCATACCGGCACACGCAACATTGAAGGGTATAACGAACATATTCGCCAACAGAACGAAACGGTACCAGAA
CAGCAGCCGCTCTTACCGTATATCGTCGTCATCATTGACGAGCTGGCTGATTTGATGATGGTGGCGTCTTCGGATGTCGA
AGAAGCGATCACCCGCTTAGCGCAAATGGCGCGCGCTGCCGGCATCCATTTAATCATTGCCACTCAACGCCCATCGGTCG
ATGTCATTACCGGCGTCATCAAAGCGAACATCCCATCTCGTATCGCTTTTAGCGTCTCGTCGCAAATCGATTCACGCACC
ATTTTGGATATGGGCGGAGCGGAAAAATTGCTTGGCCGTGGCGACATGCTATTTTTACCAATGGGAGCGTCAAAACCAGT
GCGTGTCCAAGGAGCGTTTGTATCCGATCAGGAAGTGGAAGAGGTTGTTCAGTTTGTCATCGGCCAGCAGCAGGCGCAAT
ACTATGAGGAAATGATCGTCCAAGATGGAGAAGCGAACTCCTCAGCAGTCGAAGATGATCTGTACGAAGAAGCTGTCCGT
CTTGTCGTGGAAATGCAAAGCGCCTCTGTTTCAATGTTGCAGCGCCGCTTCCGCATCGGTTATAATCGCGCCGCCCGGCT
CATCGATGCCATGGAGGAGCGCGGCGTTGTCGGTCCGTATGAAGGCAGCAAGCCGCGCGCTGTTCTTTGGTCAAAAGAAG
ATTTAAAAAAGACGTCATAA

Upstream 100 bases:

>100_bases
TGTTCAGCGGTTCATGATATAATAATAGGGAAGCAGAAAAAAGCAGCCATTGTTGGCTGCTTTTTTCCAGCTTGCCAATT
CATTCATGCTGGAGTGAGCG

Downstream 100 bases:

>100_bases
ACAGGGAAGCAGGCAGGTTCATTTCACCTGCCTGCTCAAAGGTGTATCATATTGGAAGCGCTACCAACCATATTTCTTTT
TTTTCGACAAAATTTGATTA

Product: DNA translocase

Products: NA

Alternate protein names: DNA translocase SpoIIIE; Stage III sporulation protein E [H]

Number of amino acids: Translated: 779; Mature: 779

Protein sequence:

>779_residues
MMAKRKRKKRGKPSRKQPWAEAIRFELIGLGLLTVAVVAMARLGLVGETLVLISRFFFGEWYMLLVGGLFILSFILIWKR
EWPSWASRPFVGASIIAAAFLLLSHGKLFELMSRRGELDPSVIRTTWELFWNEANGKETAIDLGGGMVGALLFAASYQLF
DALGTKWICFILFVVGFIVLTGKSLRETAGRLIVLVATFLRQEWLAFVEDMKQWVTGRKRRANNGRKRRKLQDKAAAQQE
DEPAEAGTAEPEDELLSPPPIISDFAAVRSAVELEEEKQPPTEGDDGGNGDASTPPLAFSEHENTNYDLPPLELLRLPKP
AGQSADHANIYANARKLEKTFQSFGVKAKVTQVHLGPAVTKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGK
SAIGIEVPNEEIATVSLREVLEAVEHTRPEAKLLIPLGRDISGEVVAAELNKMPHLLIAGATGSGKSVCINGIIVSLLMR
TKPHEVKLMMIDPKMVELSVYNGIPHLLTPVVTDAKKAAQALKKVVQEMERRYELFSHTGTRNIEGYNEHIRQQNETVPE
QQPLLPYIVVIIDELADLMMVASSDVEEAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQIDSRT
ILDMGGAEKLLGRGDMLFLPMGASKPVRVQGAFVSDQEVEEVVQFVIGQQQAQYYEEMIVQDGEANSSAVEDDLYEEAVR
LVVEMQSASVSMLQRRFRIGYNRAARLIDAMEERGVVGPYEGSKPRAVLWSKEDLKKTS

Sequences:

>Translated_779_residues
MMAKRKRKKRGKPSRKQPWAEAIRFELIGLGLLTVAVVAMARLGLVGETLVLISRFFFGEWYMLLVGGLFILSFILIWKR
EWPSWASRPFVGASIIAAAFLLLSHGKLFELMSRRGELDPSVIRTTWELFWNEANGKETAIDLGGGMVGALLFAASYQLF
DALGTKWICFILFVVGFIVLTGKSLRETAGRLIVLVATFLRQEWLAFVEDMKQWVTGRKRRANNGRKRRKLQDKAAAQQE
DEPAEAGTAEPEDELLSPPPIISDFAAVRSAVELEEEKQPPTEGDDGGNGDASTPPLAFSEHENTNYDLPPLELLRLPKP
AGQSADHANIYANARKLEKTFQSFGVKAKVTQVHLGPAVTKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGK
SAIGIEVPNEEIATVSLREVLEAVEHTRPEAKLLIPLGRDISGEVVAAELNKMPHLLIAGATGSGKSVCINGIIVSLLMR
TKPHEVKLMMIDPKMVELSVYNGIPHLLTPVVTDAKKAAQALKKVVQEMERRYELFSHTGTRNIEGYNEHIRQQNETVPE
QQPLLPYIVVIIDELADLMMVASSDVEEAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQIDSRT
ILDMGGAEKLLGRGDMLFLPMGASKPVRVQGAFVSDQEVEEVVQFVIGQQQAQYYEEMIVQDGEANSSAVEDDLYEEAVR
LVVEMQSASVSMLQRRFRIGYNRAARLIDAMEERGVVGPYEGSKPRAVLWSKEDLKKTS
>Mature_779_residues
MMAKRKRKKRGKPSRKQPWAEAIRFELIGLGLLTVAVVAMARLGLVGETLVLISRFFFGEWYMLLVGGLFILSFILIWKR
EWPSWASRPFVGASIIAAAFLLLSHGKLFELMSRRGELDPSVIRTTWELFWNEANGKETAIDLGGGMVGALLFAASYQLF
DALGTKWICFILFVVGFIVLTGKSLRETAGRLIVLVATFLRQEWLAFVEDMKQWVTGRKRRANNGRKRRKLQDKAAAQQE
DEPAEAGTAEPEDELLSPPPIISDFAAVRSAVELEEEKQPPTEGDDGGNGDASTPPLAFSEHENTNYDLPPLELLRLPKP
AGQSADHANIYANARKLEKTFQSFGVKAKVTQVHLGPAVTKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGK
SAIGIEVPNEEIATVSLREVLEAVEHTRPEAKLLIPLGRDISGEVVAAELNKMPHLLIAGATGSGKSVCINGIIVSLLMR
TKPHEVKLMMIDPKMVELSVYNGIPHLLTPVVTDAKKAAQALKKVVQEMERRYELFSHTGTRNIEGYNEHIRQQNETVPE
QQPLLPYIVVIIDELADLMMVASSDVEEAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQIDSRT
ILDMGGAEKLLGRGDMLFLPMGASKPVRVQGAFVSDQEVEEVVQFVIGQQQAQYYEEMIVQDGEANSSAVEDDLYEEAVR
LVVEMQSASVSMLQRRFRIGYNRAARLIDAMEERGVVGPYEGSKPRAVLWSKEDLKKTS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=493, Percent_Identity=50.3042596348884, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 86049; Mature: 86049

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAKRKRKKRGKPSRKQPWAEAIRFELIGLGLLTVAVVAMARLGLVGETLVLISRFFFGE
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYMLLVGGLFILSFILIWKREWPSWASRPFVGASIIAAAFLLLSHGKLFELMSRRGELDP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCH
SVIRTTWELFWNEANGKETAIDLGGGMVGALLFAASYQLFDALGTKWICFILFVVGFIVL
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGKSLRETAGRLIVLVATFLRQEWLAFVEDMKQWVTGRKRRANNGRKRRKLQDKAAAQQE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCC
DEPAEAGTAEPEDELLSPPPIISDFAAVRSAVELEEEKQPPTEGDDGGNGDASTPPLAFS
CCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEC
EHENTNYDLPPLELLRLPKPAGQSADHANIYANARKLEKTFQSFGVKAKVTQVHLGPAVT
CCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEE
KYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSAIGIEVPNEEIATVSLREV
EEEECCCCCCCHHHHHCCCCHHHHEEEECCEEEECCCCCCCEEEEECCCCHHHHHHHHHH
LEAVEHTRPEAKLLIPLGRDISGEVVAAELNKMPHLLIAGATGSGKSVCINGIIVSLLMR
HHHHHCCCCCCEEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
TKPHEVKLMMIDPKMVELSVYNGIPHLLTPVVTDAKKAAQALKKVVQEMERRYELFSHTG
CCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TRNIEGYNEHIRQQNETVPEQQPLLPYIVVIIDELADLMMVASSDVEEAITRLAQMARAA
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQIDSRTILDMGGAEKLLGRGDMLFLP
CEEEEEEECCCCHHHHHHHHHCCCCCHHEEHHHHCCCCCCEECCCCHHHHHCCCCEEEEE
MGASKPVRVQGAFVSDQEVEEVVQFVIGQQQAQYYEEMIVQDGEANSSAVEDDLYEEAVR
CCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LVVEMQSASVSMLQRRFRIGYNRAARLIDAMEERGVVGPYEGSKPRAVLWSKEDLKKTS
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHCCCC
>Mature Secondary Structure
MMAKRKRKKRGKPSRKQPWAEAIRFELIGLGLLTVAVVAMARLGLVGETLVLISRFFFGE
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYMLLVGGLFILSFILIWKREWPSWASRPFVGASIIAAAFLLLSHGKLFELMSRRGELDP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCH
SVIRTTWELFWNEANGKETAIDLGGGMVGALLFAASYQLFDALGTKWICFILFVVGFIVL
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGKSLRETAGRLIVLVATFLRQEWLAFVEDMKQWVTGRKRRANNGRKRRKLQDKAAAQQE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCC
DEPAEAGTAEPEDELLSPPPIISDFAAVRSAVELEEEKQPPTEGDDGGNGDASTPPLAFS
CCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEC
EHENTNYDLPPLELLRLPKPAGQSADHANIYANARKLEKTFQSFGVKAKVTQVHLGPAVT
CCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEE
KYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSAIGIEVPNEEIATVSLREV
EEEECCCCCCCHHHHHCCCCHHHHEEEECCEEEECCCCCCCEEEEECCCCHHHHHHHHHH
LEAVEHTRPEAKLLIPLGRDISGEVVAAELNKMPHLLIAGATGSGKSVCINGIIVSLLMR
HHHHHCCCCCCEEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
TKPHEVKLMMIDPKMVELSVYNGIPHLLTPVVTDAKKAAQALKKVVQEMERRYELFSHTG
CCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TRNIEGYNEHIRQQNETVPEQQPLLPYIVVIIDELADLMMVASSDVEEAITRLAQMARAA
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQIDSRTILDMGGAEKLLGRGDMLFLP
CEEEEEEECCCCHHHHHHHHHCCCCCHHEEHHHHCCCCCCEECCCCHHHHHCCCCEEEEE
MGASKPVRVQGAFVSDQEVEEVVQFVIGQQQAQYYEEMIVQDGEANSSAVEDDLYEEAVR
CCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LVVEMQSASVSMLQRRFRIGYNRAARLIDAMEERGVVGPYEGSKPRAVLWSKEDLKKTS
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3129532; 2507870; 9384377; 8160014; 10588743; 11062134; 11778051 [H]