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The map label for this gene is rnhB

Identifier: 138894726

GI number: 138894726

Start: 1124743

End: 1125522

Strand: Direct

Name: rnhB

Synonym: GTNG_1058

Alternate gene names: 138894726

Gene position: 1124743-1125522 (Clockwise)

Preceding gene: 138894725

Following gene: 138894727

Centisome position: 31.68

GC content: 58.85

Gene sequence:

>780_bases
ATGAAACAGTATACGGTCAAAGAAATTGAAGCGCTGCTTCCAGAGCTCGAAGGAGAAAGCGACCCACGCTGGGAGATGCT
GCGGCGCGATGAGCGGAAAAGCGTGCAGGCGCTTCTTGCCCGCTTTGTTAAGCAAAAGGAGCGGGAGAAAGCGGCACGGC
AGCGGTGGGAAGAGCTGATGCGCTATGAGCGTGAACTATATGCCGCTGGCATCGAGCGAATTGCCGGCATTGACGAAGCC
GGGCGCGGACCGCTGGCCGGCCCGGTCGTCGCTGCGGCGGTCATTTTGCCGAAAGACGCCTATTTGCCCGGGCTTGACGA
CTCGAAACGGCTGACGCCAGCCAAGCGCGAGGCGCTATTTGCGCAAATTGAGGAGTGCGCCGTCGCGATCGGTGTCGGCA
TTGTAAGCGCGGCCGAAATCGATGAATGGAACATTTATGAAGCGACGAAGCAGGCAATGGCCAAAGCGGTTGCCGCGCTC
TCGCCGTCGCCAGAGCATTTGCTTGTCGATGCGATGACCGTGCCGTGTGCACTGCCGCAGCAACGTCTCATAAAAGGCGA
TGCCAACAGCGCCTCGATCGCTGCTGCGTCAATCATTGCCAAAGTGACACGTGACCGATGGATGCATGAGCTTGATCGCC
GCTATCCGCAATATGGATTTGCCCGTCATATGGGCTACGGGACGCCGGAGCATCTTGCAGCGATTCGCCGCTATGGCGTG
ACGGATGAACATCGTCGTTCGTTCGCGCCGGTAAGGGAAGCGCTCGGCGTTCAATCATAG

Upstream 100 bases:

>100_bases
GGACGTAATGCGTCTGGCGGGCGTTTTTCCTTTGAATGAATGTTTCGCTTCACAACGCGCGGAATGCGTCCGATAGTATA
AGTAGAAAAGGGAGAGGGTT

Downstream 100 bases:

>100_bases
CCGACAAGGTGCGTTGTAGCAATGCGGATCGAAGGGGGATGCGCTCTCTAAGCTAGGCCGGAATGAAAGGATGGGAAGCG
AATGGTAGAGCGGATGGAAC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKQYTVKEIEALLPELEGESDPRWEMLRRDERKSVQALLARFVKQKEREKAARQRWEELMRYERELYAAGIERIAGIDEA
GRGPLAGPVVAAAVILPKDAYLPGLDDSKRLTPAKREALFAQIEECAVAIGVGIVSAAEIDEWNIYEATKQAMAKAVAAL
SPSPEHLLVDAMTVPCALPQQRLIKGDANSASIAAASIIAKVTRDRWMHELDRRYPQYGFARHMGYGTPEHLAAIRRYGV
TDEHRRSFAPVREALGVQS

Sequences:

>Translated_259_residues
MKQYTVKEIEALLPELEGESDPRWEMLRRDERKSVQALLARFVKQKEREKAARQRWEELMRYERELYAAGIERIAGIDEA
GRGPLAGPVVAAAVILPKDAYLPGLDDSKRLTPAKREALFAQIEECAVAIGVGIVSAAEIDEWNIYEATKQAMAKAVAAL
SPSPEHLLVDAMTVPCALPQQRLIKGDANSASIAAASIIAKVTRDRWMHELDRRYPQYGFARHMGYGTPEHLAAIRRYGV
TDEHRRSFAPVREALGVQS
>Mature_259_residues
MKQYTVKEIEALLPELEGESDPRWEMLRRDERKSVQALLARFVKQKEREKAARQRWEELMRYERELYAAGIERIAGIDEA
GRGPLAGPVVAAAVILPKDAYLPGLDDSKRLTPAKREALFAQIEECAVAIGVGIVSAAEIDEWNIYEATKQAMAKAVAAL
SPSPEHLLVDAMTVPCALPQQRLIKGDANSASIAAASIIAKVTRDRWMHELDRRYPQYGFARHMGYGTPEHLAAIRRYGV
TDEHRRSFAPVREALGVQS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=187, Percent_Identity=49.1978609625668, Blast_Score=171, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_GEOTN (A4IM80)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001125179.1
- ProteinModelPortal:   A4IM80
- SMR:   A4IM80
- STRING:   A4IM80
- GeneID:   4966000
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_1058
- NMPDR:   fig|420246.5.peg.1027
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   A4IM80
- ProtClustDB:   PRK00015
- BioCyc:   GTHE420246:GTNG_1058-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 28947; Mature: 28947

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYTVKEIEALLPELEGESDPRWEMLRRDERKSVQALLARFVKQKEREKAARQRWEELM
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYERELYAAGIERIAGIDEAGRGPLAGPVVAAAVILPKDAYLPGLDDSKRLTPAKREALF
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
AQIEECAVAIGVGIVSAAEIDEWNIYEATKQAMAKAVAALSPSPEHLLVDAMTVPCALPQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCCCCH
QRLIKGDANSASIAAASIIAKVTRDRWMHELDRRYPQYGFARHMGYGTPEHLAAIRRYGV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCC
TDEHRRSFAPVREALGVQS
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQYTVKEIEALLPELEGESDPRWEMLRRDERKSVQALLARFVKQKEREKAARQRWEELM
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYERELYAAGIERIAGIDEAGRGPLAGPVVAAAVILPKDAYLPGLDDSKRLTPAKREALF
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
AQIEECAVAIGVGIVSAAEIDEWNIYEATKQAMAKAVAALSPSPEHLLVDAMTVPCALPQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCCCCH
QRLIKGDANSASIAAASIIAKVTRDRWMHELDRRYPQYGFARHMGYGTPEHLAAIRRYGV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCC
TDEHRRSFAPVREALGVQS
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA