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The map label for this gene is recG [H]

Identifier: 138894706

GI number: 138894706

Start: 1106918

End: 1108954

Strand: Direct

Name: recG [H]

Synonym: GTNG_1038

Alternate gene names: 138894706

Gene position: 1106918-1108954 (Clockwise)

Preceding gene: 138894705

Following gene: 138894707

Centisome position: 31.18

GC content: 54.1

Gene sequence:

>2037_bases
ATGCTGCAACCAGTGACGGCGGTGAAAGGCATCGGTGAAGAAACGGCGGCCGCGCTCGCCGACCTCGGCATTACGACGGT
CGGCGAGTTGCTTAACTATGCACCGTACCGGTATGACGATTACGAACAAAAAGATTTGGCCGCTGTCCGCCATGAGGAAA
AGGTGACGGTTGAAGGGAAAGTGCATAGCGCCCCGCTCCTGACGTATTACGGAAAAAAAAAGTCGCGCCTTTCCTTTCGG
TTGTTAACTGGCCGCTATTTAATCACCGTCGTTTGCTTTAACCGCCCGTATTTGAAGGGGAAAATCACCTTAAACGAAAC
GGTGACGGTAATCGGCAAATGGGATCGGCATCGGCAGACCATCAACGCGTATGAGCTTCGGTTCGGGGCTGCTCCGGAGG
CGACCGGCATTGAGCCGGTGTATTCGGTACGCAGCCCGCTGACAGTTAAGACGATGCGCCGGTTGATCAAGGCAGCGTTC
GCCCAGTTCGGCATGCACATTCCTGACTTGCTGCCGCCTGCCTTGCGACGCGCTTATCGCCTTATCGACAAACAAGAAGC
GGTTCGTGCTCTTCACTTTCCTCGTTCTCGCGAAGAGCTGCATCAGGCGCGGCGCCGGCTCGTCTATGAAGAGTTTTTGC
TTTATCAGCTGAAAATGCAGGCACTAAGAAAGGTTATGCGCGACGAACGGCGCGGTATCATCCATTCATTCCCAGAAGAA
CAGCTTGCGTCGTTTCTTTCCGGGTTACCGTTTTCGTTAACAAACGCCCAGCGGCGCGTCATCAGGGAAATTTTAGATGA
TATGCGTGCACCGAGGCAAATGAACCGGCTTTTGCAAGGAGATGTCGGCTCTGGCAAGACAGTTGTTGCCGCAGTTGCGC
TCTATGCCGCCGTGTTATCCGGGTTTCAAGGGGCGCTGATGGTGCCGACGGAAATTTTGGCTGAACAGCACGTCCGCTCG
CTTGCAGAGTTGTTTGCTGATACAGGAGTGACAGTCGAGCTGTTGACAAGTTCGGTGAAAGGAAAACGGCGCAAAGAGCT
GCTTGCGAAATTGGAGGACGGGACGGTGGATATTGTCATCGGTACACACGCCTTAATTCAAGAGGGAGTGCAGTTCCGCC
AGCTCGGTCTCGTCATTACCGATGAACAGCACCGATTCGGCGTCGAGCAGCGCCGCGTTTTGCGTGAGAAAGGACACGCG
CCGGATGTGTTGATGATGACGGCGACGCCCATCCCACGCACACTCGCCATCACAGCGTTTGGCGATATGGATGTTTCAGT
GCTCGATGAAATGCCGGCCGGACGAAAAAAAGTGGAGACGTATTGGGTGAAGCATAACCAGTTTGCTCGTGTGCTTGATT
TTATTGAAAAAGAACTGCGGCGCGGTCATCAAGCATATGTGATTTGCCCGCTCATTGAAGAGTCGGAAAAATTGGATGTG
CAAAACGCCATTGATGTCCATAGTCAGCTCGTCTATTACTACCGTGGGAAATATGAAGTCGGCCTCATGCACGGCCGATT
GTCGGCCGATGAAAAAGAAGCCGTCATGCGAGCGTTCAGCGAAAACCGCATCCACGTACTCGTTTCAACGACCGTCGTTG
AAGTTGGAGTGAACGTGCCGAACGCGACAGTGATGGTCATTTATGATGCTGAGCGATTTGGACTTGCCCAACTTCACCAA
TTGCGCGGCCGGGTCGGGCGCGGTGATGCCCAGTCGTACTGTATTTTAATCGCGGATCCGAAGTCGGAAATCGGCAAAGA
ACGAATGCACATTATGACGGAAACGACGGACGGGTTCGTGCTTGCGGAGAAAGACCTAGAGCTGCGCGGACCGGGTGATT
TTTTTGGCACGAAACAAAGCGGACTCCCGGAATTCCAATTCGGCGACCCGGTGCATGATTACCGCATTTTAGAAGTCGCC
CGCCGCGATGCGGCCAAGCTCGTTTCGTCCGCTGCGTTTTGGCGCGATGAGGCGTACGCCGGGTTGCGAGCCGAACTGGA
AGCGTCCGGCGTGCTTGATGGGGAAAAACTAGATTGA

Upstream 100 bases:

>100_bases
CACTCAAAGAAACTGCGCAAGGGGGGCTGGCCGCTACGCCGGCAGGCCGCGCCATTGCGGCCCGTATTTTCGGTGCGGCG
GCGACAAAGTGAATGAAACG

Downstream 100 bases:

>100_bases
TAGACGAACGGTGAGGCGGTCGGGGTGCATGCGCGCCCCGCTGTTTTTTATGGGCGTCTTTTTTTTTTCGGAGCATCGAT
TTGGGCTTCACGGCGGACTA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MLQPVTAVKGIGEETAAALADLGITTVGELLNYAPYRYDDYEQKDLAAVRHEEKVTVEGKVHSAPLLTYYGKKKSRLSFR
LLTGRYLITVVCFNRPYLKGKITLNETVTVIGKWDRHRQTINAYELRFGAAPEATGIEPVYSVRSPLTVKTMRRLIKAAF
AQFGMHIPDLLPPALRRAYRLIDKQEAVRALHFPRSREELHQARRRLVYEEFLLYQLKMQALRKVMRDERRGIIHSFPEE
QLASFLSGLPFSLTNAQRRVIREILDDMRAPRQMNRLLQGDVGSGKTVVAAVALYAAVLSGFQGALMVPTEILAEQHVRS
LAELFADTGVTVELLTSSVKGKRRKELLAKLEDGTVDIVIGTHALIQEGVQFRQLGLVITDEQHRFGVEQRRVLREKGHA
PDVLMMTATPIPRTLAITAFGDMDVSVLDEMPAGRKKVETYWVKHNQFARVLDFIEKELRRGHQAYVICPLIEESEKLDV
QNAIDVHSQLVYYYRGKYEVGLMHGRLSADEKEAVMRAFSENRIHVLVSTTVVEVGVNVPNATVMVIYDAERFGLAQLHQ
LRGRVGRGDAQSYCILIADPKSEIGKERMHIMTETTDGFVLAEKDLELRGPGDFFGTKQSGLPEFQFGDPVHDYRILEVA
RRDAAKLVSSAAFWRDEAYAGLRAELEASGVLDGEKLD

Sequences:

>Translated_678_residues
MLQPVTAVKGIGEETAAALADLGITTVGELLNYAPYRYDDYEQKDLAAVRHEEKVTVEGKVHSAPLLTYYGKKKSRLSFR
LLTGRYLITVVCFNRPYLKGKITLNETVTVIGKWDRHRQTINAYELRFGAAPEATGIEPVYSVRSPLTVKTMRRLIKAAF
AQFGMHIPDLLPPALRRAYRLIDKQEAVRALHFPRSREELHQARRRLVYEEFLLYQLKMQALRKVMRDERRGIIHSFPEE
QLASFLSGLPFSLTNAQRRVIREILDDMRAPRQMNRLLQGDVGSGKTVVAAVALYAAVLSGFQGALMVPTEILAEQHVRS
LAELFADTGVTVELLTSSVKGKRRKELLAKLEDGTVDIVIGTHALIQEGVQFRQLGLVITDEQHRFGVEQRRVLREKGHA
PDVLMMTATPIPRTLAITAFGDMDVSVLDEMPAGRKKVETYWVKHNQFARVLDFIEKELRRGHQAYVICPLIEESEKLDV
QNAIDVHSQLVYYYRGKYEVGLMHGRLSADEKEAVMRAFSENRIHVLVSTTVVEVGVNVPNATVMVIYDAERFGLAQLHQ
LRGRVGRGDAQSYCILIADPKSEIGKERMHIMTETTDGFVLAEKDLELRGPGDFFGTKQSGLPEFQFGDPVHDYRILEVA
RRDAAKLVSSAAFWRDEAYAGLRAELEASGVLDGEKLD
>Mature_678_residues
MLQPVTAVKGIGEETAAALADLGITTVGELLNYAPYRYDDYEQKDLAAVRHEEKVTVEGKVHSAPLLTYYGKKKSRLSFR
LLTGRYLITVVCFNRPYLKGKITLNETVTVIGKWDRHRQTINAYELRFGAAPEATGIEPVYSVRSPLTVKTMRRLIKAAF
AQFGMHIPDLLPPALRRAYRLIDKQEAVRALHFPRSREELHQARRRLVYEEFLLYQLKMQALRKVMRDERRGIIHSFPEE
QLASFLSGLPFSLTNAQRRVIREILDDMRAPRQMNRLLQGDVGSGKTVVAAVALYAAVLSGFQGALMVPTEILAEQHVRS
LAELFADTGVTVELLTSSVKGKRRKELLAKLEDGTVDIVIGTHALIQEGVQFRQLGLVITDEQHRFGVEQRRVLREKGHA
PDVLMMTATPIPRTLAITAFGDMDVSVLDEMPAGRKKVETYWVKHNQFARVLDFIEKELRRGHQAYVICPLIEESEKLDV
QNAIDVHSQLVYYYRGKYEVGLMHGRLSADEKEAVMRAFSENRIHVLVSTTVVEVGVNVPNATVMVIYDAERFGLAQLHQ
LRGRVGRGDAQSYCILIADPKSEIGKERMHIMTETTDGFVLAEKDLELRGPGDFFGTKQSGLPEFQFGDPVHDYRILEVA
RRDAAKLVSSAAFWRDEAYAGLRAELEASGVLDGEKLD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=667, Percent_Identity=39.28035982009, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1787357, Length=401, Percent_Identity=38.4039900249377, Blast_Score=263, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76454; Mature: 76454

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00435 PEROXIDASE_1 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQPVTAVKGIGEETAAALADLGITTVGELLNYAPYRYDDYEQKDLAAVRHEEKVTVEGK
CCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECC
VHSAPLLTYYGKKKSRLSFRLLTGRYLITVVCFNRPYLKGKITLNETVTVIGKWDRHRQT
CCCCCEEEECCCCCCCEEEEEECCCEEEEEEEECCCEEEEEEEECCEEEEEECCHHHHHH
INAYELRFGAAPEATGIEPVYSVRSPLTVKTMRRLIKAAFAQFGMHIPDLLPPALRRAYR
HHHHEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LIDKQEAVRALHFPRSREELHQARRRLVYEEFLLYQLKMQALRKVMRDERRGIIHSFPEE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
QLASFLSGLPFSLTNAQRRVIREILDDMRAPRQMNRLLQGDVGSGKTVVAAVALYAAVLS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GFQGALMVPTEILAEQHVRSLAELFADTGVTVELLTSSVKGKRRKELLAKLEDGTVDIVI
CCCCCEECHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHCCCCEEEEE
GTHALIQEGVQFRQLGLVITDEQHRFGVEQRRVLREKGHAPDVLMMTATPIPRTLAITAF
CCHHHHHCCHHEEHCCEEEECCHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEE
GDMDVSVLDEMPAGRKKVETYWVKHNQFARVLDFIEKELRRGHQAYVICPLIEESEKLDV
CCCCHHHHHCCCCCCHHHHHHEECHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
QNAIDVHSQLVYYYRGKYEVGLMHGRLSADEKEAVMRAFSENRIHVLVSTTVVEVGVNVP
HHHHHHHHHEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCC
NATVMVIYDAERFGLAQLHQLRGRVGRGDAQSYCILIADPKSEIGKERMHIMTETTDGFV
CCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHHHCHHHHEEEEECCCCEE
LAEKDLELRGPGDFFGTKQSGLPEFQFGDPVHDYRILEVARRDAAKLVSSAAFWRDEAYA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLRAELEASGVLDGEKLD
CCHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLQPVTAVKGIGEETAAALADLGITTVGELLNYAPYRYDDYEQKDLAAVRHEEKVTVEGK
CCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECC
VHSAPLLTYYGKKKSRLSFRLLTGRYLITVVCFNRPYLKGKITLNETVTVIGKWDRHRQT
CCCCCEEEECCCCCCCEEEEEECCCEEEEEEEECCCEEEEEEEECCEEEEEECCHHHHHH
INAYELRFGAAPEATGIEPVYSVRSPLTVKTMRRLIKAAFAQFGMHIPDLLPPALRRAYR
HHHHEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LIDKQEAVRALHFPRSREELHQARRRLVYEEFLLYQLKMQALRKVMRDERRGIIHSFPEE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
QLASFLSGLPFSLTNAQRRVIREILDDMRAPRQMNRLLQGDVGSGKTVVAAVALYAAVLS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GFQGALMVPTEILAEQHVRSLAELFADTGVTVELLTSSVKGKRRKELLAKLEDGTVDIVI
CCCCCEECHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHHHHHHHCCCCEEEEE
GTHALIQEGVQFRQLGLVITDEQHRFGVEQRRVLREKGHAPDVLMMTATPIPRTLAITAF
CCHHHHHCCHHEEHCCEEEECCHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEE
GDMDVSVLDEMPAGRKKVETYWVKHNQFARVLDFIEKELRRGHQAYVICPLIEESEKLDV
CCCCHHHHHCCCCCCHHHHHHEECHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
QNAIDVHSQLVYYYRGKYEVGLMHGRLSADEKEAVMRAFSENRIHVLVSTTVVEVGVNVP
HHHHHHHHHEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCC
NATVMVIYDAERFGLAQLHQLRGRVGRGDAQSYCILIADPKSEIGKERMHIMTETTDGFV
CCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHHHCHHHHEEEEECCCCEE
LAEKDLELRGPGDFFGTKQSGLPEFQFGDPVHDYRILEVARRDAAKLVSSAAFWRDEAYA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLRAELEASGVLDGEKLD
CCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]