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The map label for this gene is sdaAA [H]

Identifier: 138894705

GI number: 138894705

Start: 1106028

End: 1106909

Strand: Direct

Name: sdaAA [H]

Synonym: GTNG_1037

Alternate gene names: 138894705

Gene position: 1106028-1106909 (Clockwise)

Preceding gene: 138894704

Following gene: 138894706

Centisome position: 31.15

GC content: 55.33

Gene sequence:

>882_bases
ATGTTTCGCAATGTCGCTGAACTTGTAGAGTTAGCTGAAAAAGAGCAAATCAAAATCGCGGAAGTAATGATTCGACAAGA
AATAGAAGTGAGTGGGCGAAGCCGGGAAGAGATTGTTGCGCAAATGGATCGTCATCTTGAGGTGATGGAGCGGGCAGTCG
AGAGAGGGCTGCAAGGGGTTGTGTCCCGATCTGGGTTGACTGGCGGCGATGCAATGCGAATGCAGCGCTATATTGAAGCG
GGGCGATTTTTGTCTGGGGAAACAATTTTGGACGCCGTCAGCAAAGCGATGGCAACAAACGAAGTGAACGCATCGATGGG
TGTCATTTGCGCCACACCGACAGCGGGCTCGGCCGGTGTCGTCCCGGGGACGCTGTTCGCGGTAAAGGAGAAATTGCAGC
CGACAAGAAAAGAAATGATTGAATTTTTGTTTACAGCCGGAGCGTTTGGCTATGTTGTTGCCAATAATGCGTCCATTTCC
GGCGCTGCCGGCGGTTGCCAGGCGGAAGTTGGTTCAGCGGCCGGCATGGCTGCTGCCGCGCTCGTTGAGTTGGCCGGCGG
TACGCCCAGCCAAGCAGCTGAAGCGATGGCCATCGCGTTAAAAAATATGCTTGGATTAGTCTGTGACCCCGTTGCTGGTC
TTGTTGAAGTGCCGTGTGTGAAGCGAAATGCCATGGGAGCGGCGAATGCCATGATCGCCGCTGATATGGCGTTAGCTGGC
GTCAAAAGCCGCATTCCATGCGACGAAGTGATTGAAGCGATGTATCGTATCGGTGCGGCAATGCCAGTCGCACTCAAAGA
AACTGCGCAAGGGGGGCTGGCCGCTACGCCGGCAGGCCGCGCCATTGCGGCCCGTATTTTCGGTGCGGCGGCGACAAAGT
GA

Upstream 100 bases:

>100_bases
TCAGGTCACGAAGCTTGTCGATTAAAAAAAGAAAGCGGTTGCGAACGGGCATGGAAGTGAAACAGCAGCGGTGCTTTGTC
AAGAAAGGATGGGATAATGA

Downstream 100 bases:

>100_bases
ATGAAACGATGCTGCAACCAGTGACGGCGGTGAAAGGCATCGGTGAAGAAACGGCGGCCGCGCTCGCCGACCTCGGCATT
ACGACGGTCGGCGAGTTGCT

Product: L-serine dehydratase subunit alpha

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MFRNVAELVELAEKEQIKIAEVMIRQEIEVSGRSREEIVAQMDRHLEVMERAVERGLQGVVSRSGLTGGDAMRMQRYIEA
GRFLSGETILDAVSKAMATNEVNASMGVICATPTAGSAGVVPGTLFAVKEKLQPTRKEMIEFLFTAGAFGYVVANNASIS
GAAGGCQAEVGSAAGMAAAALVELAGGTPSQAAEAMAIALKNMLGLVCDPVAGLVEVPCVKRNAMGAANAMIAADMALAG
VKSRIPCDEVIEAMYRIGAAMPVALKETAQGGLAATPAGRAIAARIFGAAATK

Sequences:

>Translated_293_residues
MFRNVAELVELAEKEQIKIAEVMIRQEIEVSGRSREEIVAQMDRHLEVMERAVERGLQGVVSRSGLTGGDAMRMQRYIEA
GRFLSGETILDAVSKAMATNEVNASMGVICATPTAGSAGVVPGTLFAVKEKLQPTRKEMIEFLFTAGAFGYVVANNASIS
GAAGGCQAEVGSAAGMAAAALVELAGGTPSQAAEAMAIALKNMLGLVCDPVAGLVEVPCVKRNAMGAANAMIAADMALAG
VKSRIPCDEVIEAMYRIGAAMPVALKETAQGGLAATPAGRAIAARIFGAAATK
>Mature_293_residues
MFRNVAELVELAEKEQIKIAEVMIRQEIEVSGRSREEIVAQMDRHLEVMERAVERGLQGVVSRSGLTGGDAMRMQRYIEA
GRFLSGETILDAVSKAMATNEVNASMGVICATPTAGSAGVVPGTLFAVKEKLQPTRKEMIEFLFTAGAFGYVVANNASIS
GAAGGCQAEVGSAAGMAAAALVELAGGTPSQAAEAMAIALKNMLGLVCDPVAGLVEVPCVKRNAMGAANAMIAADMALAG
VKSRIPCDEVIEAMYRIGAAMPVALKETAQGGLAATPAGRAIAARIFGAAATK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=280, Percent_Identity=37.1428571428571, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1789161, Length=285, Percent_Identity=36.4912280701754, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1788116, Length=280, Percent_Identity=35.7142857142857, Blast_Score=154, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30204; Mature: 30204

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRNVAELVELAEKEQIKIAEVMIRQEIEVSGRSREEIVAQMDRHLEVMERAVERGLQGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRSGLTGGDAMRMQRYIEAGRFLSGETILDAVSKAMATNEVNASMGVICATPTAGSAGV
HHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
VPGTLFAVKEKLQPTRKEMIEFLFTAGAFGYVVANNASISGAAGGCQAEVGSAAGMAAAA
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCHHHHHHHH
LVELAGGTPSQAAEAMAIALKNMLGLVCDPVAGLVEVPCVKRNAMGAANAMIAADMALAG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHH
VKSRIPCDEVIEAMYRIGAAMPVALKETAQGGLAATPAGRAIAARIFGAAATK
HHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFRNVAELVELAEKEQIKIAEVMIRQEIEVSGRSREEIVAQMDRHLEVMERAVERGLQGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRSGLTGGDAMRMQRYIEAGRFLSGETILDAVSKAMATNEVNASMGVICATPTAGSAGV
HHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
VPGTLFAVKEKLQPTRKEMIEFLFTAGAFGYVVANNASISGAAGGCQAEVGSAAGMAAAA
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHCCHHHHHHHH
LVELAGGTPSQAAEAMAIALKNMLGLVCDPVAGLVEVPCVKRNAMGAANAMIAADMALAG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHH
VKSRIPCDEVIEAMYRIGAAMPVALKETAQGGLAATPAGRAIAARIFGAAATK
HHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]