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The map label for this gene is paaF [C]

Identifier: 138894641

GI number: 138894641

Start: 1036609

End: 1037403

Strand: Direct

Name: paaF [C]

Synonym: GTNG_0971

Alternate gene names: 138894641

Gene position: 1036609-1037403 (Clockwise)

Preceding gene: 138894640

Following gene: 138894642

Centisome position: 29.2

GC content: 55.6

Gene sequence:

>795_bases
ATGCATGCCCAATTTATCATACGAAAGGGGAGACATGGTATGGAAGCCATAGTGGAGCATTATAACGGTATCGCGCTGTT
TACGATTTGCCGCCCCGAAAGGCGCAACGCGATCAACTTTGCTGTGATGCATGCCCTTGAACAGGCAATGGAGCAAGCGG
CGGCCGATGACAAAGTGAAAGTGTTTGCCATTACCGGCGCCGGCGACGAGGCCTTTTGTTCCGGCGGCGATTTAAGAGAG
TTCGGACATTTGCGCGGCGCGGAGGCAAAACAAATGCTTAGGCGCATGGGGGAGTTGTTGTACAAACTACTGACGTTTCC
GAAACCGACAGCAGCGCTTGTCAACGGAACGGCAATGGGAGGGGGCTGCGAGTTGGCGACCGCCTGTGATTTCCGCTTTG
TCAAGGAGGGGAGTCGAATTGGGTTCGTTCAAGGCCGGCTTGGTATTACAACCGGCTGGGGCGGCGCGTCCATGCTGTTT
GAAAAGCTTCCGTATGCGCGGGCACTCGACTTGTTGTTGCGCGCTGAGCCGATGGCGGCTGAGGAGATGGCAATGTGCGG
CTGGGCTGATGCGGTTCTGTCGGCGGATCGTTGGTGTGAACAGTGGCAAGCGCGGCTTGCTCCCTATACAGCGCGGTCGC
TTGCTGTCTTGCAAGCCTATAAGGCTGTGGCAGGCGAAAAATGGCGAATGACTTGGTTTCGTGAGCAATTTTTCGCCGAA
ATCGATCGGTGTGCTGGGCTTTGGGGATCGGCTGAGCATGAACAGGCATTGCGTCCTTTTTTGCGCAAGAAGTAA

Upstream 100 bases:

>100_bases
AAGGCTGTCCGAAAATAGGGCAGCCTTTTTATTATATGGAGGAAACAATGCCGTTTTGTCCGTGGACTCGTTTTTTCGTC
ACGGGGCAGGAAAACGGCGC

Downstream 100 bases:

>100_bases
TTTTTTCCTTCTACCGTTTCTATTAGCCGCATACATATAATGACAAAGCGGCAATAAGGAGGGGAAGGAGATGACGGGAG
TACGCCAAGACGCATGGACG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MHAQFIIRKGRHGMEAIVEHYNGIALFTICRPERRNAINFAVMHALEQAMEQAAADDKVKVFAITGAGDEAFCSGGDLRE
FGHLRGAEAKQMLRRMGELLYKLLTFPKPTAALVNGTAMGGGCELATACDFRFVKEGSRIGFVQGRLGITTGWGGASMLF
EKLPYARALDLLLRAEPMAAEEMAMCGWADAVLSADRWCEQWQARLAPYTARSLAVLQAYKAVAGEKWRMTWFREQFFAE
IDRCAGLWGSAEHEQALRPFLRKK

Sequences:

>Translated_264_residues
MHAQFIIRKGRHGMEAIVEHYNGIALFTICRPERRNAINFAVMHALEQAMEQAAADDKVKVFAITGAGDEAFCSGGDLRE
FGHLRGAEAKQMLRRMGELLYKLLTFPKPTAALVNGTAMGGGCELATACDFRFVKEGSRIGFVQGRLGITTGWGGASMLF
EKLPYARALDLLLRAEPMAAEEMAMCGWADAVLSADRWCEQWQARLAPYTARSLAVLQAYKAVAGEKWRMTWFREQFFAE
IDRCAGLWGSAEHEQALRPFLRKK
>Mature_264_residues
MHAQFIIRKGRHGMEAIVEHYNGIALFTICRPERRNAINFAVMHALEQAMEQAAADDKVKVFAITGAGDEAFCSGGDLRE
FGHLRGAEAKQMLRRMGELLYKLLTFPKPTAALVNGTAMGGGCELATACDFRFVKEGSRIGFVQGRLGITTGWGGASMLF
EKLPYARALDLLLRAEPMAAEEMAMCGWADAVLSADRWCEQWQARLAPYTARSLAVLQAYKAVAGEKWRMTWFREQFFAE
IDRCAGLWGSAEHEQALRPFLRKK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI213417737, Length=240, Percent_Identity=29.5833333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI157694516, Length=240, Percent_Identity=29.5833333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI31542718, Length=175, Percent_Identity=25.7142857142857, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=25.609756097561, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI68989263, Length=176, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI260274832, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI157694520, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI45643119, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI260275230, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4502327, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787659, Length=208, Percent_Identity=35.0961538461538, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788597, Length=189, Percent_Identity=31.2169312169312, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790281, Length=188, Percent_Identity=29.2553191489362, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI221142681, Length=176, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788682, Length=176, Percent_Identity=25, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=174, Percent_Identity=28.1609195402299, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25141363, Length=194, Percent_Identity=30.9278350515464, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=212, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=26.4227642276423, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=180, Percent_Identity=26.1111111111111, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=180, Percent_Identity=26.1111111111111, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=180, Percent_Identity=26.1111111111111, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=182, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24653139, Length=189, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357171, Length=179, Percent_Identity=30.7262569832402, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI20129971, Length=177, Percent_Identity=29.9435028248588, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653477, Length=177, Percent_Identity=29.9435028248588, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24650670, Length=184, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654903, Length=183, Percent_Identity=25.6830601092896, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29429; Mature: 29429

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAQFIIRKGRHGMEAIVEHYNGIALFTICRPERRNAINFAVMHALEQAMEQAAADDKVK
CCCHHEECCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VFAITGAGDEAFCSGGDLREFGHLRGAEAKQMLRRMGELLYKLLTFPKPTAALVNGTAMG
EEEEECCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
GGCELATACDFRFVKEGSRIGFVQGRLGITTGWGGASMLFEKLPYARALDLLLRAEPMAA
CCCCHHHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCH
EEMAMCGWADAVLSADRWCEQWQARLAPYTARSLAVLQAYKAVAGEKWRMTWFREQFFAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IDRCAGLWGSAEHEQALRPFLRKK
HHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHAQFIIRKGRHGMEAIVEHYNGIALFTICRPERRNAINFAVMHALEQAMEQAAADDKVK
CCCHHEECCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VFAITGAGDEAFCSGGDLREFGHLRGAEAKQMLRRMGELLYKLLTFPKPTAALVNGTAMG
EEEEECCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
GGCELATACDFRFVKEGSRIGFVQGRLGITTGWGGASMLFEKLPYARALDLLLRAEPMAA
CCCCHHHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCH
EEMAMCGWADAVLSADRWCEQWQARLAPYTARSLAVLQAYKAVAGEKWRMTWFREQFFAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IDRCAGLWGSAEHEQALRPFLRKK
HHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA