Click here to switch to the map view.

The map label for this gene is coaD [H]

Identifier: 138894634

GI number: 138894634

Start: 1030295

End: 1030789

Strand: Direct

Name: coaD [H]

Synonym: GTNG_0964

Alternate gene names: 138894634

Gene position: 1030295-1030789 (Clockwise)

Preceding gene: 138894633

Following gene: 138894636

Centisome position: 29.02

GC content: 48.48

Gene sequence:

>495_bases
ATGGCGAGCATTGCCGTTTGCCCGGGGAGCTTTGACCCTGTGACATACGGGCATTTGGATATTATTAAGCGGGGGGCGAA
AGTGTTTGACCAAGTTTATGTTGCGGTGTTAAACAACTCATCGAAAAAGCCGTTGTTTACCGTCGAGGAGCGGATGGAGT
TGCTGCGTGAGGTGACGCGGACGCTCGATAACGTCCATGTGGAATCGTTCCACGGTCTGCTTGTTGATTATGCCCGAAGC
AAAAAGGCGAACGCCATTTTGCGCGGCTTGCGTGCCGTGTCTGATTTTGAGTATGAAATGCAAATTACGTCGATGAACCG
TGTCCTCGATGAGAACATTGAAACGTTTTTTATGATGACAAACAGTCAGTATGCATTTTTAAGCTCAAGTATCGTCAAAG
AGGTTGCGAAATATAATGGCGACATTTCTGAGCTCGTTCCCCCGGTCGTTGAAGCGGCGCTAAAGCGGAAATTTGCGTCT
GCAGTTGCCGATTGA

Upstream 100 bases:

>100_bases
GAAGAAGTCGGCAACTTAAAGCAATGGAAACGGGAAACGTATGGCATTACCGGCATCACCATTTATCGCCGGATAGACGA
ACAGAAAGGGGACGAAAGCG

Downstream 100 bases:

>100_bases
CAGCCAAGATGGAACAGTGCCCGCTCGGCAACTGAAATACGGCTTTGGAGTTGGCTGATAATGAAAACATAAACAGTGTG
GACTTGGCTCACCGGATGGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERMELLREVTRTLDNVHVESFHGLLVDYARS
KKANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMTNSQYAFLSSSIVKEVAKYNGDISELVPPVVEAALKRKFAS
AVAD

Sequences:

>Translated_164_residues
MASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERMELLREVTRTLDNVHVESFHGLLVDYARS
KKANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMTNSQYAFLSSSIVKEVAKYNGDISELVPPVVEAALKRKFAS
AVAD
>Mature_163_residues
ASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERMELLREVTRTLDNVHVESFHGLLVDYARSK
KANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMTNSQYAFLSSSIVKEVAKYNGDISELVPPVVEAALKRKFASA
VAD

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=46.5408805031447, Blast_Score=166, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18387; Mature: 18256

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERMELLREVTR
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
TLDNVHVESFHGLLVDYARSKKANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEE
NSQYAFLSSSIVKEVAKYNGDISELVPPVVEAALKRKFASAVAD
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERMELLREVTR
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
TLDNVHVESFHGLLVDYARSKKANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEE
NSQYAFLSSSIVKEVAKYNGDISELVPPVVEAALKRKFASAVAD
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA