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The map label for this gene is pyc [H]

Identifier: 138894614

GI number: 138894614

Start: 1012995

End: 1016438

Strand: Direct

Name: pyc [H]

Synonym: GTNG_0944

Alternate gene names: 138894614

Gene position: 1012995-1016438 (Clockwise)

Preceding gene: 138894613

Following gene: 138894616

Centisome position: 28.53

GC content: 52.15

Gene sequence:

>3444_bases
ATGAAGACAAGACGAATTCGCAAAGTGCTCGTAGCTAACCGCGGGGAGATCGCCATCCGCGTTTTCCGCGCCTGCACGGA
GCTTGGCATCCGCACCGTGGCCATTTACTCGAAGGAAGATGTCGGCTCATACCACCGCTATAAAGCGGATGAAGCGTATT
TAGTCGGTGAAGGAAAAAAGCCGATTGAGGCGTATTTGGATATTGAAGGCATCATTGAGATTGCCAAGGCCCACGATGTC
GATGCGATTCACCCAGGATATGGGTTTTTGTCAGAAAATATTCAATTTGCTAAACGGTGCCGTGAAGAAGGAATTATTTT
TATTGGCCCGAATGAGAACCATTTGGACATGTTCGGCGACAAGGTGAAAGCGCGCCATGCGGCGGTGAACGCTGGCATTC
CGGTCATTCCGGGCAGCGACGGGCCGGTCGACGGCCTTGAGGACGTTGTCCGCTTCGCCGAAGCGCACGGCTATCCGATC
ATCATTAAAGCAGCACTTGGCGGCGGTGGGCGCGGCATGCGCATCGTCCGTTCGAAGTCGGAAGTTAAAGAAGCGTTTGA
GCGTGCCAAATCGGAAGCAAAAGCGGCGTTTGGCAGCGATGAGGTGTATGTTGAAAAGTTGATCGAAAATCCAAAGCACA
TTGAAGTGCAAATTTTAGGTGACTATGAAGGAAATATTGTTCACCTTTATGAACGCGACTGCTCGGTGCAGCGCCGCCAC
CAAAAAGTCGTCGAAGTCGCGCCGAGCGTCTCGCTGTCGGACGAGCTGCGCCAACGCATTTGCGAGGCAGCGGTTCAGCT
TATGAGAAGCGTCGGTTATGTCAATGCCGGCACGGTCGAATTTCTCGTTTCGGGTGATGAGTTTTATTTCATCGAAGTCA
ACCCGCGCATTCAAGTCGAGCATACGATCACCGAGATGATTACTGGAATTGATATCGTCCAGTCGCAAATTTTAATTGCT
GATGGCTGTTCGCTTCATAGCCATGAAGTCGGCATTCCGAAGCAGGAAGACATCCGCATTAACGGTTATGCCATTCAGTC
GCGGGTGACGACGGAAGACCCGCTCAATAACTTTATGCCAGATACTGGGAAAATCATGGCGTATCGCTCCGGTGGGGGCT
TTGGTGTACGTTTGGACGCCGGCAACGGTTTCCAAGGGGCAGTCATTACGCCGTATTACGATTCCTTGCTCGTCAAATTG
TCGACATGGGCGTTGACGTTTGAGCAGGCAGCAAGAAAAATGCTGCGCAACTTGCGCGAGTTCCGCATTCGCGGTATTAA
AACGAACATTCCGTTCTTGGAAAATGTCGTCCAACATCCGAAGTTTTTATCAGGCGAATACGATACGTCGTTCATCGATA
CGACGCCGGAACTATTCGTGTTCCCACGCCGGAAAGACCGCGGAACGAAAATGCTCACTTACATCGGCACAGTGACGGTC
AATGGATTCCCAGGTATCGGCAAAAAGAAAAAGCCGGTGTTTGACAAGCCGCGCTTGCCAAAATTGAGCGAGGCAGAGCC
GATCCCGGCCGGAACGAAGCAAATTTTGGACAAGCATGGCCCCGAGGGGCTTGTCCGCTGGATTCAAGAACAGCCGCGGG
TGCTCTTGACCGATACGACGTTCCGGGACGCTCATCAGTCACTGTTGGCGACACGAGTCCGCACGGTCGATTTAGTGCGT
GCAGCCGAGCCGACGGCGCGCTTATTGCCGAATTTATTCTCGCTTGAAATGTGGGGCGGGGCGACGTTTGATGTGGCGTA
TCGCTTTTTAAAAGAGGATCCGTGGGATCGGCTTCTGAAGCTGCGCGAGCGCATCCCGAACGTGTTGTTCCAAATGTTGC
TCCGTTCTGCCAACGCCGTAGGCTACAAAAACTATCCGGACAACGTCATCCGCGAGTTCGTCGAAAAATCGGCGCATGCT
GGCATCGATGTGTTCCGAATTTTCGACAGTTTAAACTGGGTGAAAGGAATGACGGTGGCGATCGACGCCGTCCGGCAGAG
CGGCAAAATCGCTGAAGCGGCGATTTGCTATACGGGTGATATTTTAGATCCGAGCCGGTCGAAATACAATTTGGATTACT
ATAAGGCCCTTGCGAAAGAGCTTGAACAGGCGGGTGCGCACATTTTGGCCATTAAAGATATGGCGGGGCTCTTGAAGCCG
CAGGCGGCGCATGTGCTCATTTCCGCGCTCAAGGAAACAGTCGACATTCCGATTCATTTGCATACGCACGACACGAGCGG
TAACGGCATTTATACGTACGCGAAAGCGATTGAAGCCGGCGTTGATATTGTTGATGTCGCCATCAGTTCGATGGCCGGCT
TAACGTCTCAGCCGAGCGCCAATACGCTTTACTATGCGCTTGAAGGGACCGAGCGGGCGCCGGAAGTCGACATTTACGGT
CTTGAGCAGTTAGCGCGCTATTGGGAAGATGTGCGCAAGTTTTATCAAGAATTTGAAAGCGGCATGAACGCGCCGCATAC
GGAAGTGTACATGCACGAAATGCCAGGCGGTCAATACAGCAACTTGCAGCAGCAGGCGAAAGCGGTCGGTCTCGGCGATC
GGTGGGATGAAGTGAAAGAAATGTACCGCCGCGTCAACGACTTGTTCGGCGATATTGTCAAAGTGACGCCGTCATCGAAA
GTCGTCGGCGATATGGCGCTTTACATGGTGCAAAACAACTTGACGGAACAAGACATTTTCGAGCGCGGCGAAACGCTGAA
CTTCCCTGATTCAGTCGTCGAGCTGTTTGAAGGATATTTAGGCCAGCCGCACGGCGGATTCCCGAAAGAGTTGCAGCGCA
TTATTTTAAAAGGACGCGAGCCGATCACTGTCCGTCCGGGGGAACTGCTCGAGCCGGTTGATTTTGAGCAAATGAAAAAA
GAGCTGTATGACAAGCTTGGCCGCGAAGTGACCGACTTTGATGCCATTGCGTACGCCCTTTATCCGAAAGTGTTTCTTGA
ATATGCAGAAACGGTGGAAAAATACGGCGATGTGTCTGTACTCGATACACCGACGTTCTTGTATGGCATGCGCCTTGGCG
AGGAAATTGAAGTGGAAATCGAGCGCGGAAAAACGTTGATCGTTAAGCTTGTGTCGATCGGCCAGCCGCAGGCGGACGGT
ACACGCGTCGTCTACTTCGAGCTGAACGGTCAACCGCGTGAAGTTGTCATCCGCGATGAAAGCATTAAAACCGCAGTCGT
TGAGCACATTAAAGCGGATCGGACGAACCCGAACCATATTGCGGCGACGATGCCGGGTACGGTTGTTAAAGTGCTTGTCG
AAAAAGGGGAAAAAGTCGACAAAGGGGACCATTTAATGGTCACGGAAGCAATGAAAATGGAAACGACCGTGCAAGCACCG
TTTGCCGGTGTTGTCAAAGACATTTACGTCAAAAGCGGCGATGCGATCCAGGCAGGCGATTTGCTCATCGAGTTGTCCAA
ATAA

Upstream 100 bases:

>100_bases
AAATGACTGTCGACAGACAGAAAAGAGGTCTGACTTTTTAGAAAGTGTATTTACAAAATAGAAAAAGTTTTATAGTTTAA
ATTAGAAAGGAGGAAAGACG

Downstream 100 bases:

>100_bases
AAAAACATTGATCTTGGCACAAGCCGGTTTCCTAAAAAAGGGATGCCCAACATTTGTGGGCATCCCTTTTATGCAACGAG
TGAGCGTTATTTTAATGGCG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1147; Mature: 1147

Protein sequence:

>1147_residues
MKTRRIRKVLVANRGEIAIRVFRACTELGIRTVAIYSKEDVGSYHRYKADEAYLVGEGKKPIEAYLDIEGIIEIAKAHDV
DAIHPGYGFLSENIQFAKRCREEGIIFIGPNENHLDMFGDKVKARHAAVNAGIPVIPGSDGPVDGLEDVVRFAEAHGYPI
IIKAALGGGGRGMRIVRSKSEVKEAFERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRH
QKVVEVAPSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGDEFYFIEVNPRIQVEHTITEMITGIDIVQSQILIA
DGCSLHSHEVGIPKQEDIRINGYAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDAGNGFQGAVITPYYDSLLVKL
STWALTFEQAARKMLRNLREFRIRGIKTNIPFLENVVQHPKFLSGEYDTSFIDTTPELFVFPRRKDRGTKMLTYIGTVTV
NGFPGIGKKKKPVFDKPRLPKLSEAEPIPAGTKQILDKHGPEGLVRWIQEQPRVLLTDTTFRDAHQSLLATRVRTVDLVR
AAEPTARLLPNLFSLEMWGGATFDVAYRFLKEDPWDRLLKLRERIPNVLFQMLLRSANAVGYKNYPDNVIREFVEKSAHA
GIDVFRIFDSLNWVKGMTVAIDAVRQSGKIAEAAICYTGDILDPSRSKYNLDYYKALAKELEQAGAHILAIKDMAGLLKP
QAAHVLISALKETVDIPIHLHTHDTSGNGIYTYAKAIEAGVDIVDVAISSMAGLTSQPSANTLYYALEGTERAPEVDIYG
LEQLARYWEDVRKFYQEFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRWDEVKEMYRRVNDLFGDIVKVTPSSK
VVGDMALYMVQNNLTEQDIFERGETLNFPDSVVELFEGYLGQPHGGFPKELQRIILKGREPITVRPGELLEPVDFEQMKK
ELYDKLGREVTDFDAIAYALYPKVFLEYAETVEKYGDVSVLDTPTFLYGMRLGEEIEVEIERGKTLIVKLVSIGQPQADG
TRVVYFELNGQPREVVIRDESIKTAVVEHIKADRTNPNHIAATMPGTVVKVLVEKGEKVDKGDHLMVTEAMKMETTVQAP
FAGVVKDIYVKSGDAIQAGDLLIELSK

Sequences:

>Translated_1147_residues
MKTRRIRKVLVANRGEIAIRVFRACTELGIRTVAIYSKEDVGSYHRYKADEAYLVGEGKKPIEAYLDIEGIIEIAKAHDV
DAIHPGYGFLSENIQFAKRCREEGIIFIGPNENHLDMFGDKVKARHAAVNAGIPVIPGSDGPVDGLEDVVRFAEAHGYPI
IIKAALGGGGRGMRIVRSKSEVKEAFERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRH
QKVVEVAPSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGDEFYFIEVNPRIQVEHTITEMITGIDIVQSQILIA
DGCSLHSHEVGIPKQEDIRINGYAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDAGNGFQGAVITPYYDSLLVKL
STWALTFEQAARKMLRNLREFRIRGIKTNIPFLENVVQHPKFLSGEYDTSFIDTTPELFVFPRRKDRGTKMLTYIGTVTV
NGFPGIGKKKKPVFDKPRLPKLSEAEPIPAGTKQILDKHGPEGLVRWIQEQPRVLLTDTTFRDAHQSLLATRVRTVDLVR
AAEPTARLLPNLFSLEMWGGATFDVAYRFLKEDPWDRLLKLRERIPNVLFQMLLRSANAVGYKNYPDNVIREFVEKSAHA
GIDVFRIFDSLNWVKGMTVAIDAVRQSGKIAEAAICYTGDILDPSRSKYNLDYYKALAKELEQAGAHILAIKDMAGLLKP
QAAHVLISALKETVDIPIHLHTHDTSGNGIYTYAKAIEAGVDIVDVAISSMAGLTSQPSANTLYYALEGTERAPEVDIYG
LEQLARYWEDVRKFYQEFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRWDEVKEMYRRVNDLFGDIVKVTPSSK
VVGDMALYMVQNNLTEQDIFERGETLNFPDSVVELFEGYLGQPHGGFPKELQRIILKGREPITVRPGELLEPVDFEQMKK
ELYDKLGREVTDFDAIAYALYPKVFLEYAETVEKYGDVSVLDTPTFLYGMRLGEEIEVEIERGKTLIVKLVSIGQPQADG
TRVVYFELNGQPREVVIRDESIKTAVVEHIKADRTNPNHIAATMPGTVVKVLVEKGEKVDKGDHLMVTEAMKMETTVQAP
FAGVVKDIYVKSGDAIQAGDLLIELSK
>Mature_1147_residues
MKTRRIRKVLVANRGEIAIRVFRACTELGIRTVAIYSKEDVGSYHRYKADEAYLVGEGKKPIEAYLDIEGIIEIAKAHDV
DAIHPGYGFLSENIQFAKRCREEGIIFIGPNENHLDMFGDKVKARHAAVNAGIPVIPGSDGPVDGLEDVVRFAEAHGYPI
IIKAALGGGGRGMRIVRSKSEVKEAFERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRH
QKVVEVAPSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGDEFYFIEVNPRIQVEHTITEMITGIDIVQSQILIA
DGCSLHSHEVGIPKQEDIRINGYAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDAGNGFQGAVITPYYDSLLVKL
STWALTFEQAARKMLRNLREFRIRGIKTNIPFLENVVQHPKFLSGEYDTSFIDTTPELFVFPRRKDRGTKMLTYIGTVTV
NGFPGIGKKKKPVFDKPRLPKLSEAEPIPAGTKQILDKHGPEGLVRWIQEQPRVLLTDTTFRDAHQSLLATRVRTVDLVR
AAEPTARLLPNLFSLEMWGGATFDVAYRFLKEDPWDRLLKLRERIPNVLFQMLLRSANAVGYKNYPDNVIREFVEKSAHA
GIDVFRIFDSLNWVKGMTVAIDAVRQSGKIAEAAICYTGDILDPSRSKYNLDYYKALAKELEQAGAHILAIKDMAGLLKP
QAAHVLISALKETVDIPIHLHTHDTSGNGIYTYAKAIEAGVDIVDVAISSMAGLTSQPSANTLYYALEGTERAPEVDIYG
LEQLARYWEDVRKFYQEFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRWDEVKEMYRRVNDLFGDIVKVTPSSK
VVGDMALYMVQNNLTEQDIFERGETLNFPDSVVELFEGYLGQPHGGFPKELQRIILKGREPITVRPGELLEPVDFEQMKK
ELYDKLGREVTDFDAIAYALYPKVFLEYAETVEKYGDVSVLDTPTFLYGMRLGEEIEVEIERGKTLIVKLVSIGQPQADG
TRVVYFELNGQPREVVIRDESIKTAVVEHIKADRTNPNHIAATMPGTVVKVLVEKGEKVDKGDHLMVTEAMKMETTVQAP
FAGVVKDIYVKSGDAIQAGDLLIELSK

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1150, Percent_Identity=52, Blast_Score=1170, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1150, Percent_Identity=52, Blast_Score=1170, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1150, Percent_Identity=52, Blast_Score=1170, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=464, Percent_Identity=44.6120689655172, Blast_Score=399, Evalue=1e-110,
Organism=Homo sapiens, GI189095269, Length=456, Percent_Identity=45.6140350877193, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI65506442, Length=456, Percent_Identity=45.6140350877193, Blast_Score=375, Evalue=1e-103,
Organism=Homo sapiens, GI295821183, Length=457, Percent_Identity=45.7330415754923, Blast_Score=375, Evalue=1e-103,
Organism=Homo sapiens, GI38679960, Length=508, Percent_Identity=31.8897637795276, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679974, Length=508, Percent_Identity=31.8897637795276, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679971, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI38679977, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI38679967, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI134142062, Length=518, Percent_Identity=30.8880308880309, Blast_Score=237, Evalue=5e-62,
Organism=Escherichia coli, GI1789654, Length=447, Percent_Identity=45.6375838926174, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1786216, Length=284, Percent_Identity=24.2957746478873, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1150, Percent_Identity=51.304347826087, Blast_Score=1169, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=467, Percent_Identity=43.4689507494647, Blast_Score=354, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI71987519, Length=496, Percent_Identity=40.7258064516129, Blast_Score=340, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI71997168, Length=514, Percent_Identity=29.5719844357977, Blast_Score=212, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71997163, Length=514, Percent_Identity=29.5719844357977, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI133931226, Length=498, Percent_Identity=29.3172690763052, Blast_Score=206, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1154, Percent_Identity=50.5199306759099, Blast_Score=1130, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1154, Percent_Identity=50.6932409012132, Blast_Score=1117, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=38.2222222222222, Blast_Score=298, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6323863, Length=471, Percent_Identity=31.6348195329087, Blast_Score=225, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=30.078125, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24652212, Length=1145, Percent_Identity=53.0131004366812, Blast_Score=1187, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1145, Percent_Identity=53.0131004366812, Blast_Score=1187, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1145, Percent_Identity=53.0131004366812, Blast_Score=1187, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1145, Percent_Identity=53.0131004366812, Blast_Score=1187, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1145, Percent_Identity=53.0131004366812, Blast_Score=1187, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1162, Percent_Identity=52.5817555938038, Blast_Score=1179, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1162, Percent_Identity=52.5817555938038, Blast_Score=1179, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1162, Percent_Identity=52.5817555938038, Blast_Score=1179, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1162, Percent_Identity=52.5817555938038, Blast_Score=1179, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1162, Percent_Identity=52.5817555938038, Blast_Score=1179, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=471, Percent_Identity=41.6135881104034, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24651759, Length=428, Percent_Identity=40.4205607476636, Blast_Score=318, Evalue=2e-86,
Organism=Drosophila melanogaster, GI161076409, Length=513, Percent_Identity=31.1890838206628, Blast_Score=241, Evalue=2e-63,
Organism=Drosophila melanogaster, GI161076407, Length=513, Percent_Identity=31.1890838206628, Blast_Score=241, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24586460, Length=513, Percent_Identity=31.1890838206628, Blast_Score=241, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24586458, Length=513, Percent_Identity=31.1890838206628, Blast_Score=241, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128301; Mature: 128301

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRRIRKVLVANRGEIAIRVFRACTELGIRTVAIYSKEDVGSYHRYKADEAYLVGEGKK
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCEEEEECCCC
PIEAYLDIEGIIEIAKAHDVDAIHPGYGFLSENIQFAKRCREEGIIFIGPNENHLDMFGD
CHHHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
KVKARHAAVNAGIPVIPGSDGPVDGLEDVVRFAEAHGYPIIIKAALGGGGRGMRIVRSKS
HHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECHH
EVKEAFERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCHHHHHH
QKVVEVAPSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGDEFYFIEVNPRIQVE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEEECCCEEEH
HTITEMITGIDIVQSQILIADGCSLHSHEVGIPKQEDIRINGYAIQSRVTTEDPLNNFMP
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHCCC
DTGKIMAYRSGGGFGVRLDAGNGFQGAVITPYYDSLLVKLSTWALTFEQAARKMLRNLRE
CCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIRGIKTNIPFLENVVQHPKFLSGEYDTSFIDTTPELFVFPRRKDRGTKMLTYIGTVTV
HHHCCCCCCCCHHHHHHCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCEEEEEEEEEEE
NGFPGIGKKKKPVFDKPRLPKLSEAEPIPAGTKQILDKHGPEGLVRWIQEQPRVLLTDTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCEEEECCC
FRDAHQSLLATRVRTVDLVRAAEPTARLLPNLFSLEMWGGATFDVAYRFLKEDPWDRLLK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHEEEECCCCHHHHHHHHHHCCCHHHHHH
LRERIPNVLFQMLLRSANAVGYKNYPDNVIREFVEKSAHAGIDVFRIFDSLNWVKGMTVA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHH
IDAVRQSGKIAEAAICYTGDILDPSRSKYNLDYYKALAKELEQAGAHILAIKDMAGLLKP
HHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHCC
QAAHVLISALKETVDIPIHLHTHDTSGNGIYTYAKAIEAGVDIVDVAISSMAGLTSQPSA
HHHHHHHHHHHHHHCCEEEEEECCCCCCCEEHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
NTLYYALEGTERAPEVDIYGLEQLARYWEDVRKFYQEFESGMNAPHTEVYMHEMPGGQYS
CEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHH
NLQQQAKAVGLGDRWDEVKEMYRRVNDLFGDIVKVTPSSKVVGDMALYMVQNNLTEQDIF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHH
ERGETLNFPDSVVELFEGYLGQPHGGFPKELQRIILKGREPITVRPGELLEPVDFEQMKK
HCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHH
ELYDKLGREVTDFDAIAYALYPKVFLEYAETVEKYGDVSVLDTPTFLYGMRLGEEIEVEI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCEEEEEE
ERGKTLIVKLVSIGQPQADGTRVVYFELNGQPREVVIRDESIKTAVVEHIKADRTNPNHI
ECCCEEEEEHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCEE
AATMPGTVVKVLVEKGEKVDKGDHLMVTEAMKMETTVQAPFAGVVKDIYVKSGDAIQAGD
EECCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECC
LLIELSK
EEEEECC
>Mature Secondary Structure
MKTRRIRKVLVANRGEIAIRVFRACTELGIRTVAIYSKEDVGSYHRYKADEAYLVGEGKK
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCEEEEECCCC
PIEAYLDIEGIIEIAKAHDVDAIHPGYGFLSENIQFAKRCREEGIIFIGPNENHLDMFGD
CHHHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
KVKARHAAVNAGIPVIPGSDGPVDGLEDVVRFAEAHGYPIIIKAALGGGGRGMRIVRSKS
HHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECHH
EVKEAFERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCHHHHHH
QKVVEVAPSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGDEFYFIEVNPRIQVE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEEECCCEEEH
HTITEMITGIDIVQSQILIADGCSLHSHEVGIPKQEDIRINGYAIQSRVTTEDPLNNFMP
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHCCC
DTGKIMAYRSGGGFGVRLDAGNGFQGAVITPYYDSLLVKLSTWALTFEQAARKMLRNLRE
CCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIRGIKTNIPFLENVVQHPKFLSGEYDTSFIDTTPELFVFPRRKDRGTKMLTYIGTVTV
HHHCCCCCCCCHHHHHHCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCEEEEEEEEEEE
NGFPGIGKKKKPVFDKPRLPKLSEAEPIPAGTKQILDKHGPEGLVRWIQEQPRVLLTDTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCEEEECCC
FRDAHQSLLATRVRTVDLVRAAEPTARLLPNLFSLEMWGGATFDVAYRFLKEDPWDRLLK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHEEEECCCCHHHHHHHHHHCCCHHHHHH
LRERIPNVLFQMLLRSANAVGYKNYPDNVIREFVEKSAHAGIDVFRIFDSLNWVKGMTVA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHH
IDAVRQSGKIAEAAICYTGDILDPSRSKYNLDYYKALAKELEQAGAHILAIKDMAGLLKP
HHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHCC
QAAHVLISALKETVDIPIHLHTHDTSGNGIYTYAKAIEAGVDIVDVAISSMAGLTSQPSA
HHHHHHHHHHHHHHCCEEEEEECCCCCCCEEHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
NTLYYALEGTERAPEVDIYGLEQLARYWEDVRKFYQEFESGMNAPHTEVYMHEMPGGQYS
CEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHH
NLQQQAKAVGLGDRWDEVKEMYRRVNDLFGDIVKVTPSSKVVGDMALYMVQNNLTEQDIF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHH
ERGETLNFPDSVVELFEGYLGQPHGGFPKELQRIILKGREPITVRPGELLEPVDFEQMKK
HCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHH
ELYDKLGREVTDFDAIAYALYPKVFLEYAETVEKYGDVSVLDTPTFLYGMRLGEEIEVEI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHCCCCEEEEEE
ERGKTLIVKLVSIGQPQADGTRVVYFELNGQPREVVIRDESIKTAVVEHIKADRTNPNHI
ECCCEEEEEHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCEE
AATMPGTVVKVLVEKGEKVDKGDHLMVTEAMKMETTVQAPFAGVVKDIYVKSGDAIQAGD
EECCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECC
LLIELSK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]