Click here to switch to the map view.

The map label for this gene is glcT [H]

Identifier: 138894547

GI number: 138894547

Start: 950205

End: 951101

Strand: Direct

Name: glcT [H]

Synonym: GTNG_0877

Alternate gene names: 138894547

Gene position: 950205-951101 (Clockwise)

Preceding gene: 138894544

Following gene: 138894548

Centisome position: 26.76

GC content: 45.93

Gene sequence:

>897_bases
ATGAATAACGGGCCATTGCCGCGGAAAGGAGGGAGCTTGATGGAACAGTCGTTTCGTGTAGAAAAAGCGCTCAATAACAA
TGTGTTAATCGCTTCCCATCCAGCGTATGGCGAAGTCGTCTTGCTTGGTAAAGGGATCGGCTTCGGCAAAAAAAAGGGGG
ACGAAATTGCTGAGAGTACTGTAGAAAAATGCTTTGTTCTCAAAAATGAACGTGAACAAGAGCAATACAAAAAACTGCTC
CCTGAACTGAGCGAAGAGTTTATCGCCCTCATGAATGAGGTGATTCAACATATTAAGCAGCGTGTCGGCGTGCCATTAAA
CGAGCACATTCACGTTGCACTGACCGATCATATCGCGTTTACACTAAAGCGACTTGAACAAGGATTAGACGTCAAAAATC
CGTTTTTGGTCGAGACGAAAAGTTTGTATCCGCTTGAGTACGAAATCGCGGCTGAAGTCGCCGAGCTGATTGGGGATAAG
CTCGGGGTCGCACTGCCGGAAGGAGAAGTGGGCTTCATCACCCTCCATATTCATAGCGCTATTTCAAAACAAAGCTTGGC
AGAAGCTAATCAATATTCCCAGCTCATCGCTAAGCTTGTCGAGATTGTCAAACAGCAGCTTGGCGTCGACATCGATCGTG
AGAGTATCCACTATTTGCGTTTCGTTCGTCATTTGCGCTACGCGATCGATCGGCTGAAAAAAGGAGAAAAAGTCGAAAAA
CCAAAAAATTTGTCGAAAATCTTGAAAGAGGCTTACCCGCTATGCTATAATCTAGCATGGAAGTTAGTTAAAGTCATGCA
GCAAACGCTTCAACTGCCGGCTGACGACGCTGAGGCAGTCTATTTGACGCTGCATTTGCAGCGGCTGGCGGAAAAAAAGA
GTGGCACAACAATATAA

Upstream 100 bases:

>100_bases
CACTCTATAGTATGGAAAGAAGGGCGTCGTCCCATCCAAAAAAACGCCATCTTTTTTTCGTTGAGCGGCGGGGTGTTTCC
GGTTTATAATTAGTCGCGTA

Downstream 100 bases:

>100_bases
CATTGTCTCGCTTTACGTGTTACTGATTCGATCAGGCATGAGTAAAGAGAGCGAAACAGGACGGCAACGACCGGAATTTT
GTATTCAGGTTGTTGTAAGC

Product: transcription antiterminator

Products: NA

Alternate protein names: RNA-binding antitermination protein GlcT [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNNGPLPRKGGSLMEQSFRVEKALNNNVLIASHPAYGEVVLLGKGIGFGKKKGDEIAESTVEKCFVLKNEREQEQYKKLL
PELSEEFIALMNEVIQHIKQRVGVPLNEHIHVALTDHIAFTLKRLEQGLDVKNPFLVETKSLYPLEYEIAAEVAELIGDK
LGVALPEGEVGFITLHIHSAISKQSLAEANQYSQLIAKLVEIVKQQLGVDIDRESIHYLRFVRHLRYAIDRLKKGEKVEK
PKNLSKILKEAYPLCYNLAWKLVKVMQQTLQLPADDAEAVYLTLHLQRLAEKKSGTTI

Sequences:

>Translated_298_residues
MNNGPLPRKGGSLMEQSFRVEKALNNNVLIASHPAYGEVVLLGKGIGFGKKKGDEIAESTVEKCFVLKNEREQEQYKKLL
PELSEEFIALMNEVIQHIKQRVGVPLNEHIHVALTDHIAFTLKRLEQGLDVKNPFLVETKSLYPLEYEIAAEVAELIGDK
LGVALPEGEVGFITLHIHSAISKQSLAEANQYSQLIAKLVEIVKQQLGVDIDRESIHYLRFVRHLRYAIDRLKKGEKVEK
PKNLSKILKEAYPLCYNLAWKLVKVMQQTLQLPADDAEAVYLTLHLQRLAEKKSGTTI
>Mature_298_residues
MNNGPLPRKGGSLMEQSFRVEKALNNNVLIASHPAYGEVVLLGKGIGFGKKKGDEIAESTVEKCFVLKNEREQEQYKKLL
PELSEEFIALMNEVIQHIKQRVGVPLNEHIHVALTDHIAFTLKRLEQGLDVKNPFLVETKSLYPLEYEIAAEVAELIGDK
LGVALPEGEVGFITLHIHSAISKQSLAEANQYSQLIAKLVEIVKQQLGVDIDRESIHYLRFVRHLRYAIDRLKKGEKVEK
PKNLSKILKEAYPLCYNLAWKLVKVMQQTLQLPADDAEAVYLTLHLQRLAEKKSGTTI

Specific function: Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of Glc

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PRD domains [H]

Homologues:

Organism=Escherichia coli, GI1790160, Length=274, Percent_Identity=29.5620437956204, Blast_Score=150, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004341
- InterPro:   IPR011608
- InterPro:   IPR001550 [H]

Pfam domain/function: PF03123 CAT_RBD; PF00874 PRD [H]

EC number: NA

Molecular weight: Translated: 33636; Mature: 33636

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNGPLPRKGGSLMEQSFRVEKALNNNVLIASHPAYGEVVLLGKGIGFGKKKGDEIAEST
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHH
VEKCFVLKNEREQEQYKKLLPELSEEFIALMNEVIQHIKQRVGVPLNEHIHVALTDHIAF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
TLKRLEQGLDVKNPFLVETKSLYPLEYEIAAEVAELIGDKLGVALPEGEVGFITLHIHSA
HHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHH
ISKQSLAEANQYSQLIAKLVEIVKQQLGVDIDRESIHYLRFVRHLRYAIDRLKKGEKVEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKNLSKILKEAYPLCYNLAWKLVKVMQQTLQLPADDAEAVYLTLHLQRLAEKKSGTTI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNGPLPRKGGSLMEQSFRVEKALNNNVLIASHPAYGEVVLLGKGIGFGKKKGDEIAEST
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHH
VEKCFVLKNEREQEQYKKLLPELSEEFIALMNEVIQHIKQRVGVPLNEHIHVALTDHIAF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
TLKRLEQGLDVKNPFLVETKSLYPLEYEIAAEVAELIGDKLGVALPEGEVGFITLHIHSA
HHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHH
ISKQSLAEANQYSQLIAKLVEIVKQQLGVDIDRESIHYLRFVRHLRYAIDRLKKGEKVEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKNLSKILKEAYPLCYNLAWKLVKVMQQTLQLPADDAEAVYLTLHLQRLAEKKSGTTI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11902727; 9384377 [H]