Click here to switch to the map view.

The map label for this gene is yfjP [H]

Identifier: 138894074

GI number: 138894074

Start: 450895

End: 451761

Strand: Direct

Name: yfjP [H]

Synonym: GTNG_0400

Alternate gene names: 138894074

Gene position: 450895-451761 (Clockwise)

Preceding gene: 138894073

Following gene: 138894075

Centisome position: 12.7

GC content: 53.75

Gene sequence:

>867_bases
ATGTGGAAACGAACGATCACCGTGCCTGCGCCGTATGATTTTGCCCATGTGCTCGACCGGCTTTCGTTAGATCCGCTGAT
GGCGGTTGACGTAGAGCGACAGCGCATCACCGTGCCGCTTCATCTTGACGGCTTAAAGATACCGGTCGTAATTGAAAGCA
TCGGCACAAAAGAAGCCCCCCGTTTTGTTGTTTTGGCACCGCATTCCAATCGGCAAGAAGACATTCTTGAGCGCGTCTCC
CATTTATTCCAATGGCAGACGCCGCTTGCCCCGGTGTACGATCATTTCCGCACGACCGAGCTGGCGCCGCTGTTTGCCCG
TTATGAGGGGCTGCCATTAGTGCTTGATTTCGATTTGTATTTTTGCCTGATGAAATGTTTCATCCATCAGCAACTTCATC
TCAAAGTGGGCTATCGACTTACAGAACGGTTTGTCAAAACGTTCGGTGAGGAACGGGACGGCGTTTGGTTTTACCCGCGC
CCAGAAGATATCGCCGCCCGCTCGTATGATGACTTGCGCGCCTTACAGCTGAGCAGGCGGAAGGCGGAGTATATCGTTGA
TGTGTCGCGTCTGATTGCCGACGGAACGCTGCGACTTGATGACCTCGAGCAAATGGAAGACGGTGAAGTGATGGAGCGGT
TGACCGCCATACGAGGCATCGGGCCATGGACCGTGCAAAATTTTCTCCTGTTTGGGCTTGGCCGTCCGAACGTCTTTCCG
CCGGCTGATATTGGCTTGCAGCGGGCGGTTGAACGACTTTTTCAGCTTCCGAAGCGGCCGACTGCTAGCGAGCTGGCATT
GCTCGGCGAACGATGGAAGCCGTACACGAGTTATGCGGCTCTTTATTTGTGGAGAAGTATTGAATGA

Upstream 100 bases:

>100_bases
TTCCAACTGAATCGTATGCGGCTGCTTTGTCCGATTCGTTGGTTTGGCGGGGCGTTTTTCGTTATAATAAGGGCACGGAC
CAACGAAAAAGGTGAGGACA

Downstream 100 bases:

>100_bases
GAGGGACTGATATGACAAAGCAACAAACGAAGGTAAAGATTCAAAAAGGCGATCAATTTCCGCTGACGATTCAGCGCATC
GGCATTAACGGTGAAGGGGT

Product: DNA-3-methyladenine glycosylase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MWKRTITVPAPYDFAHVLDRLSLDPLMAVDVERQRITVPLHLDGLKIPVVIESIGTKEAPRFVVLAPHSNRQEDILERVS
HLFQWQTPLAPVYDHFRTTELAPLFARYEGLPLVLDFDLYFCLMKCFIHQQLHLKVGYRLTERFVKTFGEERDGVWFYPR
PEDIAARSYDDLRALQLSRRKAEYIVDVSRLIADGTLRLDDLEQMEDGEVMERLTAIRGIGPWTVQNFLLFGLGRPNVFP
PADIGLQRAVERLFQLPKRPTASELALLGERWKPYTSYAALYLWRSIE

Sequences:

>Translated_288_residues
MWKRTITVPAPYDFAHVLDRLSLDPLMAVDVERQRITVPLHLDGLKIPVVIESIGTKEAPRFVVLAPHSNRQEDILERVS
HLFQWQTPLAPVYDHFRTTELAPLFARYEGLPLVLDFDLYFCLMKCFIHQQLHLKVGYRLTERFVKTFGEERDGVWFYPR
PEDIAARSYDDLRALQLSRRKAEYIVDVSRLIADGTLRLDDLEQMEDGEVMERLTAIRGIGPWTVQNFLLFGLGRPNVFP
PADIGLQRAVERLFQLPKRPTASELALLGERWKPYTSYAALYLWRSIE
>Mature_288_residues
MWKRTITVPAPYDFAHVLDRLSLDPLMAVDVERQRITVPLHLDGLKIPVVIESIGTKEAPRFVVLAPHSNRQEDILERVS
HLFQWQTPLAPVYDHFRTTELAPLFARYEGLPLVLDFDLYFCLMKCFIHQQLHLKVGYRLTERFVKTFGEERDGVWFYPR
PEDIAARSYDDLRALQLSRRKAEYIVDVSRLIADGTLRLDDLEQMEDGEVMERLTAIRGIGPWTVQNFLLFGLGRPNVFP
PADIGLQRAVERLFQLPKRPTASELALLGERWKPYTSYAALYLWRSIE

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Escherichia coli, GI1788383, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 33493; Mature: 33493

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKRTITVPAPYDFAHVLDRLSLDPLMAVDVERQRITVPLHLDGLKIPVVIESIGTKEAP
CCCEEEECCCCCHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCEEEEEEEECCCCCCCC
RFVVLAPHSNRQEDILERVSHLFQWQTPLAPVYDHFRTTELAPLFARYEGLPLVLDFDLY
EEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
FCLMKCFIHQQLHLKVGYRLTERFVKTFGEERDGVWFYPRPEDIAARSYDDLRALQLSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHCCHHHHHHHHHHHH
KAEYIVDVSRLIADGTLRLDDLEQMEDGEVMERLTAIRGIGPWTVQNFLLFGLGRPNVFP
HHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
PADIGLQRAVERLFQLPKRPTASELALLGERWKPYTSYAALYLWRSIE
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MWKRTITVPAPYDFAHVLDRLSLDPLMAVDVERQRITVPLHLDGLKIPVVIESIGTKEAP
CCCEEEECCCCCHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCEEEEEEEECCCCCCCC
RFVVLAPHSNRQEDILERVSHLFQWQTPLAPVYDHFRTTELAPLFARYEGLPLVLDFDLY
EEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
FCLMKCFIHQQLHLKVGYRLTERFVKTFGEERDGVWFYPRPEDIAARSYDDLRALQLSRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHCCHHHHHHHHHHHH
KAEYIVDVSRLIADGTLRLDDLEQMEDGEVMERLTAIRGIGPWTVQNFLLFGLGRPNVFP
HHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
PADIGLQRAVERLFQLPKRPTASELALLGERWKPYTSYAALYLWRSIE
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]