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The map label for this gene is lutB [H]

Identifier: 138894041

GI number: 138894041

Start: 417027

End: 418457

Strand: Reverse

Name: lutB [H]

Synonym: GTNG_0367

Alternate gene names: 138894041

Gene position: 418457-417027 (Counterclockwise)

Preceding gene: 138894042

Following gene: 138894040

Centisome position: 11.79

GC content: 52.97

Gene sequence:

>1431_bases
ATGCCAATGAAAATCGAAAACGGGCCGTTTTGGAAACGGGTCGAAGAAAATTTACAAAATGACTTTATGCGCGGGGCAGT
CGCTGGCATGCAAGACCGCGGCTATGTGCGGCGGCTTGGCGTCATCGAAGAACTCGGCCATTGGGAGGAGTGGCGCTCGC
TCGCTGAACAAATTCGAAAGCATACTCTCGAAAACTTGGACTATTATTTAATGCAGCTCAGTGAAAACGTTGCCAAACGG
GGCGGGCATGTCTTTTTCGCCCAGACAGCCGAAGAGGCGAACGATTACATCCGACGCATCGCTTTGGAAAAACAAGCGAA
AAAAATTGTCAAATCAAAATCGATGGTGACCGAAGAAATCAACTTAAACCCGGTGCTTGAAGCCATCGGCTGTGACGTCG
TCGAAACCGATCTCGGTGAGTACATTTTACAAATTGACGACCATGACCCACCGTCACATATCGTCGGCCCGGCGCTTCAT
AAAAACAAAGAGCAAATTCGTGACGTCTTCCACCGCAAGCTCGGCTACAATAAGTCGTCCGATCCAGTTGAACTTGCGCG
TCATGCTCGTGAAACGCTGCGGCGCGACTATTTAACCGCTGACATCGGCATCACCGGCTGCAACTTCGCCATCGCCGAAT
CGGGCTCGATCACGCTCGTCACAAACGAAGGCAACGCTGATTTGGTGACGTCTTTGCCCAAAACACAAATCACAGTGATG
GGAATGGAGCGGATCGTTCCGACATTCAAGGAAATGGAAGTACTCGTCAGCATGTTGACGCGCAGCGCCGTCGGGCAAAA
ATTGACAAGCTACATCACTGTCCTCACCGGTCCACGCGAGCAAGGCGACGCCGACGGACCTGAAGAGTTCCATCTTGTCA
TCGTTGACAACGGACGCTCATCGATCTTAGGTACGGAGTTTCAGCCGGTGCTGCAATGCATCCGTTGCGCCGCCTGTGTC
AACGTCTGTCCAGTATACCGCCATATTGGTGGCCATTCATACGGCTCGATTTACTCCGGCCCGATCGGCGCGGTCTTGTC
ACCACTTTTAGGGGGGTATGACGACTACAAAGAGCTTCCATACGCGTCCTCCCTTTGCGCCGCCTGTACGGAAGTGTGCC
CGGTGAAAATTCCACTTCATGAACTGTTGATCAAACATCGCCAAATCATCGTCGAGAGGGAAGGAAAAGCGCCGGTCGCA
GAAAAATTGGCAATGAAGGCGTTTCGCCTCGGAACCGCTTCACCGTCATTGTACCGTTTCGGCACGAAATTGGCGCCAAG
CGCCTTCGCCCCGTTTGCTGAAGACGGGCGTATCACGAAAGGCCCCGGCCCGCTGAAAGCATGGACGGAAAGCCGCGTGT
TTCCCGCACCGAACAACGAACGATTCCGTGACTGGTTCCGCAATCGTCAAAAAGGAGGAAATCCATCATGA

Upstream 100 bases:

>100_bases
GAACATCGGGGGACGCATCGGACGGGTCGGCAAACCGATTCGCGTCATGCATATCGCCGAAGTATTAAATCATCGCAACT
AAAAAAGGGGGGGAACGAAG

Downstream 100 bases:

>100_bases
CGCGTGGTACGATTCAAAACCGTGACGCGTTTTTACAAAATATCGCCAAACGCCTTGGGAGAAGCCCGCGCCTGTCCGGC
GTCTCCCAACCACAATGGGA

Product: Iron-sulfur cluster-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MPMKIENGPFWKRVEENLQNDFMRGAVAGMQDRGYVRRLGVIEELGHWEEWRSLAEQIRKHTLENLDYYLMQLSENVAKR
GGHVFFAQTAEEANDYIRRIALEKQAKKIVKSKSMVTEEINLNPVLEAIGCDVVETDLGEYILQIDDHDPPSHIVGPALH
KNKEQIRDVFHRKLGYNKSSDPVELARHARETLRRDYLTADIGITGCNFAIAESGSITLVTNEGNADLVTSLPKTQITVM
GMERIVPTFKEMEVLVSMLTRSAVGQKLTSYITVLTGPREQGDADGPEEFHLVIVDNGRSSILGTEFQPVLQCIRCAACV
NVCPVYRHIGGHSYGSIYSGPIGAVLSPLLGGYDDYKELPYASSLCAACTEVCPVKIPLHELLIKHRQIIVEREGKAPVA
EKLAMKAFRLGTASPSLYRFGTKLAPSAFAPFAEDGRITKGPGPLKAWTESRVFPAPNNERFRDWFRNRQKGGNPS

Sequences:

>Translated_476_residues
MPMKIENGPFWKRVEENLQNDFMRGAVAGMQDRGYVRRLGVIEELGHWEEWRSLAEQIRKHTLENLDYYLMQLSENVAKR
GGHVFFAQTAEEANDYIRRIALEKQAKKIVKSKSMVTEEINLNPVLEAIGCDVVETDLGEYILQIDDHDPPSHIVGPALH
KNKEQIRDVFHRKLGYNKSSDPVELARHARETLRRDYLTADIGITGCNFAIAESGSITLVTNEGNADLVTSLPKTQITVM
GMERIVPTFKEMEVLVSMLTRSAVGQKLTSYITVLTGPREQGDADGPEEFHLVIVDNGRSSILGTEFQPVLQCIRCAACV
NVCPVYRHIGGHSYGSIYSGPIGAVLSPLLGGYDDYKELPYASSLCAACTEVCPVKIPLHELLIKHRQIIVEREGKAPVA
EKLAMKAFRLGTASPSLYRFGTKLAPSAFAPFAEDGRITKGPGPLKAWTESRVFPAPNNERFRDWFRNRQKGGNPS
>Mature_475_residues
PMKIENGPFWKRVEENLQNDFMRGAVAGMQDRGYVRRLGVIEELGHWEEWRSLAEQIRKHTLENLDYYLMQLSENVAKRG
GHVFFAQTAEEANDYIRRIALEKQAKKIVKSKSMVTEEINLNPVLEAIGCDVVETDLGEYILQIDDHDPPSHIVGPALHK
NKEQIRDVFHRKLGYNKSSDPVELARHARETLRRDYLTADIGITGCNFAIAESGSITLVTNEGNADLVTSLPKTQITVMG
MERIVPTFKEMEVLVSMLTRSAVGQKLTSYITVLTGPREQGDADGPEEFHLVIVDNGRSSILGTEFQPVLQCIRCAACVN
VCPVYRHIGGHSYGSIYSGPIGAVLSPLLGGYDDYKELPYASSLCAACTEVCPVKIPLHELLIKHRQIIVEREGKAPVAE
KLAMKAFRLGTASPSLYRFGTKLAPSAFAPFAEDGRITKGPGPLKAWTESRVFPAPNNERFRDWFRNRQKGGNPS

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=470, Percent_Identity=55.7446808510638, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 53122; Mature: 52991

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKIENGPFWKRVEENLQNDFMRGAVAGMQDRGYVRRLGVIEELGHWEEWRSLAEQIRK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
HTLENLDYYLMQLSENVAKRGGHVFFAQTAEEANDYIRRIALEKQAKKIVKSKSMVTEEI
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLNPVLEAIGCDVVETDLGEYILQIDDHDPPSHIVGPALHKNKEQIRDVFHRKLGYNKSS
CCCHHHHHHCCCHHHHHHHHHEEEECCCCCCCHHCCCHHHCCHHHHHHHHHHHHCCCCCC
DPVELARHARETLRRDYLTADIGITGCNFAIAESGSITLVTNEGNADLVTSLPKTQITVM
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCHHEECCCCCEEEEE
GMERIVPTFKEMEVLVSMLTRSAVGQKLTSYITVLTGPREQGDADGPEEFHLVIVDNGRS
EHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEEECCCC
SILGTEFQPVLQCIRCAACVNVCPVYRHIGGHSYGSIYSGPIGAVLSPLLGGYDDYKELP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCC
YASSLCAACTEVCPVKIPLHELLIKHRQIIVEREGKAPVAEKLAMKAFRLGTASPSLYRF
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCHHHHH
GTKLAPSAFAPFAEDGRITKGPGPLKAWTESRVFPAPNNERFRDWFRNRQKGGNPS
CCCCCCHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PMKIENGPFWKRVEENLQNDFMRGAVAGMQDRGYVRRLGVIEELGHWEEWRSLAEQIRK
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
HTLENLDYYLMQLSENVAKRGGHVFFAQTAEEANDYIRRIALEKQAKKIVKSKSMVTEEI
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLNPVLEAIGCDVVETDLGEYILQIDDHDPPSHIVGPALHKNKEQIRDVFHRKLGYNKSS
CCCHHHHHHCCCHHHHHHHHHEEEECCCCCCCHHCCCHHHCCHHHHHHHHHHHHCCCCCC
DPVELARHARETLRRDYLTADIGITGCNFAIAESGSITLVTNEGNADLVTSLPKTQITVM
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCHHEECCCCCEEEEE
GMERIVPTFKEMEVLVSMLTRSAVGQKLTSYITVLTGPREQGDADGPEEFHLVIVDNGRS
EHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEEECCCC
SILGTEFQPVLQCIRCAACVNVCPVYRHIGGHSYGSIYSGPIGAVLSPLLGGYDDYKELP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCC
YASSLCAACTEVCPVKIPLHELLIKHRQIIVEREGKAPVAEKLAMKAFRLGTASPSLYRF
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCHHHHH
GTKLAPSAFAPFAEDGRITKGPGPLKAWTESRVFPAPNNERFRDWFRNRQKGGNPS
CCCCCCHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA