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The map label for this gene is ycbL [H]

Identifier: 138894005

GI number: 138894005

Start: 375366

End: 376070

Strand: Reverse

Name: ycbL [H]

Synonym: GTNG_0331

Alternate gene names: 138894005

Gene position: 376070-375366 (Counterclockwise)

Preceding gene: 138894006

Following gene: 138894004

Centisome position: 10.59

GC content: 48.37

Gene sequence:

>705_bases
ATGAGCAAACTACTGCTAGTCGAGGATGATGAATCGCTCGCACTCGGTATTGAATTCGCCTTGCAAGACGAGGGCTATGA
AGTGTGTCGCGCTTCCACTCTCGAAGAAGGAAAAGCGCTATTTGCCTCGCAATCGTTTGATTTAATCATTTTAGACATCA
ATTTGCCCGATGGAAGCGGCTATGATTTATGCAAACATATTCGCGCCACAAGCGACGTGCCGATCTTGTTCTTGACCGCG
CTTGATGAAGAAGTGAACATCATTCTCGGCTTGGAGCTCGGCGGGGACGATTACATCACGAAGCCGTTTGGCGTCGGCGT
GTTTTTATCAAGAATTAAAGCGCTGCTCCGAAGAAGCGCAGGACATCGAGCCACGGGAATGATATTAAAAAGCGGCACCA
TCACCGTCGACCCGCTCGCGGCCACCGTCGAGAAAAACGGACAAAAAATCTCTCTTTCTGCTCAAGAATATAAGCTGCTG
CTCACATTGATGGATCGCCCTTGCACCGTCATGAGCCGCGACGAAATCTTACGCGAACTTGCCGAAGGAACGGAAGCATT
TTTCGATGAAAACACGTTAGCCGTCTATATTCGACGGCTAAGGGAAAAAATCGAAGATGACCCTAAAGAGCCTCAATATA
TCGTAACGCAAAGAGGCCTCGGGTACAAATGGAATAAAGAAGTGACGAGGGAGAAGATACTGTGA

Upstream 100 bases:

>100_bases
ATGCGGATCGCCATAATCCGCATCCTTTATTTTTCTAATTCGGCAAGCTATCATAAAAGGGAGGAAACGAACGGCTAGAG
TACACAAAGGAGGAACACGA

Downstream 100 bases:

>100_bases
TGAGCCGCGACTTTATGAACCCTGAACTGCGTCTTAGCTCTGGTGTGTTATTGTCATTAATGGCTTTCTTTTTCCTCGTT
GCTTTCATCATGTTAAAGCT

Product: transcriptional regulatory component of sensory transduction system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSKLLLVEDDESLALGIEFALQDEGYEVCRASTLEEGKALFASQSFDLIILDINLPDGSGYDLCKHIRATSDVPILFLTA
LDEEVNIILGLELGGDDYITKPFGVGVFLSRIKALLRRSAGHRATGMILKSGTITVDPLAATVEKNGQKISLSAQEYKLL
LTLMDRPCTVMSRDEILRELAEGTEAFFDENTLAVYIRRLREKIEDDPKEPQYIVTQRGLGYKWNKEVTREKIL

Sequences:

>Translated_234_residues
MSKLLLVEDDESLALGIEFALQDEGYEVCRASTLEEGKALFASQSFDLIILDINLPDGSGYDLCKHIRATSDVPILFLTA
LDEEVNIILGLELGGDDYITKPFGVGVFLSRIKALLRRSAGHRATGMILKSGTITVDPLAATVEKNGQKISLSAQEYKLL
LTLMDRPCTVMSRDEILRELAEGTEAFFDENTLAVYIRRLREKIEDDPKEPQYIVTQRGLGYKWNKEVTREKIL
>Mature_233_residues
SKLLLVEDDESLALGIEFALQDEGYEVCRASTLEEGKALFASQSFDLIILDINLPDGSGYDLCKHIRATSDVPILFLTAL
DEEVNIILGLELGGDDYITKPFGVGVFLSRIKALLRRSAGHRATGMILKSGTITVDPLAATVEKNGQKISLSAQEYKLLL
TLMDRPCTVMSRDEILRELAEGTEAFFDENTLAVYIRRLREKIEDDPKEPQYIVTQRGLGYKWNKEVTREKIL

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.9285714285714, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=35.3982300884956, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=33.6283185840708, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.0807174887892, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=37.0044052863436, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=31.8777292576419, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.6363636363636, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.0175438596491, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=32.3008849557522, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=32.579185520362, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=34.3891402714932, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=31.7180616740088, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=32.3275862068966, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=31.140350877193, Blast_Score=98, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26158; Mature: 26027

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLLLVEDDESLALGIEFALQDEGYEVCRASTLEEGKALFASQSFDLIILDINLPDGSG
CCCEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCC
YDLCKHIRATSDVPILFLTALDEEVNIILGLELGGDDYITKPFGVGVFLSRIKALLRRSA
HHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
GHRATGMILKSGTITVDPLAATVEKNGQKISLSAQEYKLLLTLMDRPCTVMSRDEILREL
CCCEEEEEEECCCEEECHHHHHHHCCCCEEEECHHHHHEEEEHHCCCCCCCCHHHHHHHH
AEGTEAFFDENTLAVYIRRLREKIEDDPKEPQYIVTQRGLGYKWNKEVTREKIL
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECCHHHHHHHCC
>Mature Secondary Structure 
SKLLLVEDDESLALGIEFALQDEGYEVCRASTLEEGKALFASQSFDLIILDINLPDGSG
CCEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCC
YDLCKHIRATSDVPILFLTALDEEVNIILGLELGGDDYITKPFGVGVFLSRIKALLRRSA
HHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
GHRATGMILKSGTITVDPLAATVEKNGQKISLSAQEYKLLLTLMDRPCTVMSRDEILREL
CCCEEEEEEECCCEEECHHHHHHHCCCCEEEECHHHHHEEEEHHCCCCCCCCHHHHHHHH
AEGTEAFFDENTLAVYIRRLREKIEDDPKEPQYIVTQRGLGYKWNKEVTREKIL
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]