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The map label for this gene is resE [H]

Identifier: 138894004

GI number: 138894004

Start: 374125

End: 375366

Strand: Reverse

Name: resE [H]

Synonym: GTNG_0330

Alternate gene names: 138894004

Gene position: 375366-374125 (Counterclockwise)

Preceding gene: 138894005

Following gene: 138894002

Centisome position: 10.57

GC content: 43.96

Gene sequence:

>1242_bases
ATGAGCCGCGACTTTATGAACCCTGAACTGCGTCTTAGCTCTGGTGTGTTATTGTCATTAATGGCTTTCTTTTTCCTCGT
TGCTTTCATCATGTTAAAGCTTCACCATGAGCAATTAAAAAGTGACTATATAGCCGTCTTCGGTTCCATTGCTTCACGAA
TTGTCGAGGAACACCCCGAACTCGAGCAAGATATCGTCCCGTTCATGACAACAGAAATCTCGCGTGAAGAAGAGGAAAAA
GGAAAGGAGATCCTAGCGCAATACGGATTAACGGAGCAATTGAACGACGAATTATTTCCTTATGTCCACACGGCGATTCA
AAAAAACGAGCGTGCAGTCGTGTTGTTGTTTCTATTGATGGCATTGTCGCTTTTTCTCCTTAATTACTCACAATATCGAA
CGCTTTACAGTCGCATTAGGCAACTTGCGCTCGCCGCAGAAAAGGTGGTGGAAGGCGACTTCAATATCATTATGAGCGAA
ACAAGGGAAGGTGACTTTTCAAAACTAGCGGTCGCCTTTAACGGCATGCGGAATACGATCCGGAATCAATTAGATGAACT
GAAAAAGGAAAAACGGTTTTTAGCCGATTTATTGTCCGACATTTCCCATCAGCTCAAAACACCACTCTCTTCCATGATCA
TCTACAATGAAATTATGTTAGGGAAACAGCTGTCGGAAGAACAGCAACGCATGTTTTTATTGCAAAACGAAAAACAACTC
GAGCGAATGAAATGGCTCATTCAAAGCCTCCTCAAACTCGCAAAACTCGACGCAAAAGCATTGCAAATGGATCGCCAACA
GCAAAGCTTAAACGAAACCGTTTGGCAATCGATCGACGATTTGCGTGAGCAAGCGGTCGAAGCAAATGTTCATATTCGCT
TTGAAAACAGTGAAGAAGTTGAATTCAACCATGACCGTCTTTGGTTGAAAGAAGCGTTCATCAATATCATAAAAAACAGC
ATCGAACACACCCCACCGGGAGGGAACATCGATATCACCATCGTCTCCCATCCGCTTTATACAAGGGTGGTGATCGCCGA
CACGGGAGAAGGCATCAGCCAAGATGATCTCCCTCACATTTTCAAACGCTTTTACAAGGCCAAAACGTCGAAAAAACCTG
ACTCGATCGGCATCGGATTGGCTTTAGCGAAATCGATCATCGAAGCGCATGGCGGCATGATTGAAGCGAAGAGCGAACTC
GGAAAAGGTACGACGTTTTCCATTACTTTTCTTAACTATTGA

Upstream 100 bases:

>100_bases
AAAAAATCGAAGATGACCCTAAAGAGCCTCAATATATCGTAACGCAAAGAGGCCTCGGGTACAAATGGAATAAAGAAGTG
ACGAGGGAGAAGATACTGTG

Downstream 100 bases:

>100_bases
CGGAAAAAGGCTGACCTTAAAGTAGCGCAAAACATCACCAACTCATACCATAAACAAATCTTCTCATGCGGAATTGTACT
TCCCGCGGTCACCTCTTGCA

Product: sensor protein ResE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSRDFMNPELRLSSGVLLSLMAFFFLVAFIMLKLHHEQLKSDYIAVFGSIASRIVEEHPELEQDIVPFMTTEISREEEEK
GKEILAQYGLTEQLNDELFPYVHTAIQKNERAVVLLFLLMALSLFLLNYSQYRTLYSRIRQLALAAEKVVEGDFNIIMSE
TREGDFSKLAVAFNGMRNTIRNQLDELKKEKRFLADLLSDISHQLKTPLSSMIIYNEIMLGKQLSEEQQRMFLLQNEKQL
ERMKWLIQSLLKLAKLDAKALQMDRQQQSLNETVWQSIDDLREQAVEANVHIRFENSEEVEFNHDRLWLKEAFINIIKNS
IEHTPPGGNIDITIVSHPLYTRVVIADTGEGISQDDLPHIFKRFYKAKTSKKPDSIGIGLALAKSIIEAHGGMIEAKSEL
GKGTTFSITFLNY

Sequences:

>Translated_413_residues
MSRDFMNPELRLSSGVLLSLMAFFFLVAFIMLKLHHEQLKSDYIAVFGSIASRIVEEHPELEQDIVPFMTTEISREEEEK
GKEILAQYGLTEQLNDELFPYVHTAIQKNERAVVLLFLLMALSLFLLNYSQYRTLYSRIRQLALAAEKVVEGDFNIIMSE
TREGDFSKLAVAFNGMRNTIRNQLDELKKEKRFLADLLSDISHQLKTPLSSMIIYNEIMLGKQLSEEQQRMFLLQNEKQL
ERMKWLIQSLLKLAKLDAKALQMDRQQQSLNETVWQSIDDLREQAVEANVHIRFENSEEVEFNHDRLWLKEAFINIIKNS
IEHTPPGGNIDITIVSHPLYTRVVIADTGEGISQDDLPHIFKRFYKAKTSKKPDSIGIGLALAKSIIEAHGGMIEAKSEL
GKGTTFSITFLNY
>Mature_412_residues
SRDFMNPELRLSSGVLLSLMAFFFLVAFIMLKLHHEQLKSDYIAVFGSIASRIVEEHPELEQDIVPFMTTEISREEEEKG
KEILAQYGLTEQLNDELFPYVHTAIQKNERAVVLLFLLMALSLFLLNYSQYRTLYSRIRQLALAAEKVVEGDFNIIMSET
REGDFSKLAVAFNGMRNTIRNQLDELKKEKRFLADLLSDISHQLKTPLSSMIIYNEIMLGKQLSEEQQRMFLLQNEKQLE
RMKWLIQSLLKLAKLDAKALQMDRQQQSLNETVWQSIDDLREQAVEANVHIRFENSEEVEFNHDRLWLKEAFINIIKNSI
EHTPPGGNIDITIVSHPLYTRVVIADTGEGISQDDLPHIFKRFYKAKTSKKPDSIGIGLALAKSIIEAHGGMIEAKSELG
KGTTFSITFLNY

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=278, Percent_Identity=27.6978417266187, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=27.536231884058, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=26.2008733624454, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=27.5555555555556, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=27.4261603375527, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=217, Percent_Identity=29.4930875576037, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=345, Percent_Identity=25.5072463768116, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=292, Percent_Identity=22.2602739726027, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=211, Percent_Identity=26.0663507109005, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=216, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=23.3480176211454, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=24.187725631769, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=25.2100840336134, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47505; Mature: 47373

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRDFMNPELRLSSGVLLSLMAFFFLVAFIMLKLHHEQLKSDYIAVFGSIASRIVEEHPE
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LEQDIVPFMTTEISREEEEKGKEILAQYGLTEQLNDELFPYVHTAIQKNERAVVLLFLLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALSLFLLNYSQYRTLYSRIRQLALAAEKVVEGDFNIIMSETREGDFSKLAVAFNGMRNTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHH
RNQLDELKKEKRFLADLLSDISHQLKTPLSSMIIYNEIMLGKQLSEEQQRMFLLQNEKQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ERMKWLIQSLLKLAKLDAKALQMDRQQQSLNETVWQSIDDLREQAVEANVHIRFENSEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
EFNHDRLWLKEAFINIIKNSIEHTPPGGNIDITIVSHPLYTRVVIADTGEGISQDDLPHI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCHHHH
FKRFYKAKTSKKPDSIGIGLALAKSIIEAHGGMIEAKSELGKGTTFSITFLNY
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCCCCEEEEEEECC
>Mature Secondary Structure 
SRDFMNPELRLSSGVLLSLMAFFFLVAFIMLKLHHEQLKSDYIAVFGSIASRIVEEHPE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LEQDIVPFMTTEISREEEEKGKEILAQYGLTEQLNDELFPYVHTAIQKNERAVVLLFLLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALSLFLLNYSQYRTLYSRIRQLALAAEKVVEGDFNIIMSETREGDFSKLAVAFNGMRNTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHH
RNQLDELKKEKRFLADLLSDISHQLKTPLSSMIIYNEIMLGKQLSEEQQRMFLLQNEKQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ERMKWLIQSLLKLAKLDAKALQMDRQQQSLNETVWQSIDDLREQAVEANVHIRFENSEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
EFNHDRLWLKEAFINIIKNSIEHTPPGGNIDITIVSHPLYTRVVIADTGEGISQDDLPHI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCHHHH
FKRFYKAKTSKKPDSIGIGLALAKSIIEAHGGMIEAKSELGKGTTFSITFLNY
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]