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The map label for this gene is dapE [H]

Identifier: 138893966

GI number: 138893966

Start: 327629

End: 328858

Strand: Direct

Name: dapE [H]

Synonym: GTNG_0290

Alternate gene names: 138893966

Gene position: 327629-328858 (Clockwise)

Preceding gene: 138893965

Following gene: 138893967

Centisome position: 9.23

GC content: 41.79

Gene sequence:

>1230_bases
ATGAATAATTATGTTACGGATTCTACCCTTCGTCTTCTTCGAGATAGGGAGGAAGTGGTTAAGCTTACACAGGCACTTGT
GCGAATTCCAAGTGTGTATCGGCCAGGAGATCCTGAGGGGAATGAACAAAAAGTGGCTCAATATGTAGCGAATTATTTAA
AACAGATGGGAGTTGAGGTGCATATAGAAGAAGTAGAACCGGGACGCCCTAATGTTATCGGTATTATCGACTCTGGAAAG
CCGGGGAAAACCATTCTTTTTGAGGGACATACGGATGTAGTAACAGAAGGGGATAGAAGTGCATGGACTTATGACCCTTT
CGGAGCGGAAATTGTTAATGGGAGAATTTATGGAAGGGGCACAAATGACACAAAAGGAAATTTAGCTTGTATGATCACCG
CTGTTCATTCTTTATTGAGGGAGAAAGAACAATGGAAAGGAAAAATTATACTTTGTATTCCTTGTGATGAAGAAGGAATG
ATGATCGGGATTAAGCACTTTATCCAAAGAGGTTGGGCGAAGGGGGTTGATGGTGCGATTATTTGTGAGCCGGAAGAAAA
TCAAGTATGTATTGCGCAAAAAGGAGCGATGAGGATTGTTATTCGTGTATATGGAAAGATGGCACATGGGGCGATTCCTT
TAAGTGGTATAAATCCAAACACAAGAATGGCGAAATTAATATGTGAGTTAGAACAACTAGAGAAACGAGAAAAAGAAAGA
TTAGGGAAACATCCGTTGCTTGGCTGGCCAAGTATTACTCCAACCATTTTGAAAGCACCTGTGCGTGGGGATGCCCAAAT
AAATGTAATTCCTGATCAATGTATGACGACGCTGGATATACGAACGATTCCGGGACAGGATCACGAAGAGCTCTGTGAAG
AAATTCAGCGTATCTTTGAACGGTTAGCCGAGGAAGATCCAGATTTTAAAGGGGAATTTGAAGTCATTGAAAACAGACCA
TGGACGAAAACGAGTAAAGATGAGCCAATTGTAAAGGCAGTGGCAGAAGCAGTGAGGAGAGTAACGAAAAAAGAACCTTA
TTACAATGGTGTACCCGGAGCGACGGATGGTACCTTTTTACACCTGGAAGGCATACCTATTGTAACTATTGGAGCAGGAG
ATCGTGAAATTCCTCATCAAGTTGATGAGTACGTAGATATCGATGAACTCGCTGAAACGACTGAAATCTATAGAACAGCA
GCTTTGCTGTTCTTAAATGAAGAGGTTTAG

Upstream 100 bases:

>100_bases
ATCATGCATTGTTTATGTGCTTACTAGTCTAATTACAAATAAAACGATGGGAATGAAAGTAGACTATGGGTTAAGTCATC
AAACAAAGGAGGTTTAATTC

Downstream 100 bases:

>100_bases
AGAATGAGGGAGTTTCGGATAGCAGTTCTTCCAGGTGATGGAATAGGTCCTGAAGTAATGAATGAGGCGTTAAAAGTTTT
ACGGATACTCAAAGATAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNNYVTDSTLRLLRDREEVVKLTQALVRIPSVYRPGDPEGNEQKVAQYVANYLKQMGVEVHIEEVEPGRPNVIGIIDSGK
PGKTILFEGHTDVVTEGDRSAWTYDPFGAEIVNGRIYGRGTNDTKGNLACMITAVHSLLREKEQWKGKIILCIPCDEEGM
MIGIKHFIQRGWAKGVDGAIICEPEENQVCIAQKGAMRIVIRVYGKMAHGAIPLSGINPNTRMAKLICELEQLEKREKER
LGKHPLLGWPSITPTILKAPVRGDAQINVIPDQCMTTLDIRTIPGQDHEELCEEIQRIFERLAEEDPDFKGEFEVIENRP
WTKTSKDEPIVKAVAEAVRRVTKKEPYYNGVPGATDGTFLHLEGIPIVTIGAGDREIPHQVDEYVDIDELAETTEIYRTA
ALLFLNEEV

Sequences:

>Translated_409_residues
MNNYVTDSTLRLLRDREEVVKLTQALVRIPSVYRPGDPEGNEQKVAQYVANYLKQMGVEVHIEEVEPGRPNVIGIIDSGK
PGKTILFEGHTDVVTEGDRSAWTYDPFGAEIVNGRIYGRGTNDTKGNLACMITAVHSLLREKEQWKGKIILCIPCDEEGM
MIGIKHFIQRGWAKGVDGAIICEPEENQVCIAQKGAMRIVIRVYGKMAHGAIPLSGINPNTRMAKLICELEQLEKREKER
LGKHPLLGWPSITPTILKAPVRGDAQINVIPDQCMTTLDIRTIPGQDHEELCEEIQRIFERLAEEDPDFKGEFEVIENRP
WTKTSKDEPIVKAVAEAVRRVTKKEPYYNGVPGATDGTFLHLEGIPIVTIGAGDREIPHQVDEYVDIDELAETTEIYRTA
ALLFLNEEV
>Mature_409_residues
MNNYVTDSTLRLLRDREEVVKLTQALVRIPSVYRPGDPEGNEQKVAQYVANYLKQMGVEVHIEEVEPGRPNVIGIIDSGK
PGKTILFEGHTDVVTEGDRSAWTYDPFGAEIVNGRIYGRGTNDTKGNLACMITAVHSLLREKEQWKGKIILCIPCDEEGM
MIGIKHFIQRGWAKGVDGAIICEPEENQVCIAQKGAMRIVIRVYGKMAHGAIPLSGINPNTRMAKLICELEQLEKREKER
LGKHPLLGWPSITPTILKAPVRGDAQINVIPDQCMTTLDIRTIPGQDHEELCEEIQRIFERLAEEDPDFKGEFEVIENRP
WTKTSKDEPIVKAVAEAVRRVTKKEPYYNGVPGATDGTFLHLEGIPIVTIGAGDREIPHQVDEYVDIDELAETTEIYRTA
ALLFLNEEV

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=382, Percent_Identity=27.2251308900524, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788816, Length=329, Percent_Identity=24.9240121580547, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789236, Length=433, Percent_Identity=24.7113163972286, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71982085, Length=395, Percent_Identity=24.5569620253165, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982082, Length=384, Percent_Identity=25, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538642, Length=363, Percent_Identity=25.8953168044077, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71982710, Length=379, Percent_Identity=25.3298153034301, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538640, Length=263, Percent_Identity=28.1368821292776, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24649206, Length=400, Percent_Identity=24.25, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356353, Length=337, Percent_Identity=24.9258160237389, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649210, Length=405, Percent_Identity=23.7037037037037, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649202, Length=402, Percent_Identity=24.1293532338308, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24649204, Length=402, Percent_Identity=24.1293532338308, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 45845; Mature: 45845

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYVTDSTLRLLRDREEVVKLTQALVRIPSVYRPGDPEGNEQKVAQYVANYLKQMGVEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
HIEEVEPGRPNVIGIIDSGKPGKTILFEGHTDVVTEGDRSAWTYDPFGAEIVNGRIYGRG
EEEECCCCCCCEEEEEECCCCCCEEEEECCCCEEECCCCCCEEECCCCCEEECCEEEECC
TNDTKGNLACMITAVHSLLREKEQWKGKIILCIPCDEEGMMIGIKHFIQRGWAKGVDGAI
CCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCEE
ICEPEENQVCIAQKGAMRIVIRVYGKMAHGAIPLSGINPNTRMAKLICELEQLEKREKER
EECCCCCCEEEECCCCCEEHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LGKHPLLGWPSITPTILKAPVRGDAQINVIPDQCMTTLDIRTIPGQDHEELCEEIQRIFE
HCCCCCCCCCCCCHHHHCCCCCCCCEEEEEHHHHHEEEEEEECCCCCHHHHHHHHHHHHH
RLAEEDPDFKGEFEVIENRPWTKTSKDEPIVKAVAEAVRRVTKKEPYYNGVPGATDGTFL
HHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
HLEGIPIVTIGAGDREIPHQVDEYVDIDELAETTEIYRTAALLFLNEEV
EECCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHEEEECCC
>Mature Secondary Structure
MNNYVTDSTLRLLRDREEVVKLTQALVRIPSVYRPGDPEGNEQKVAQYVANYLKQMGVEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
HIEEVEPGRPNVIGIIDSGKPGKTILFEGHTDVVTEGDRSAWTYDPFGAEIVNGRIYGRG
EEEECCCCCCCEEEEEECCCCCCEEEEECCCCEEECCCCCCEEECCCCCEEECCEEEECC
TNDTKGNLACMITAVHSLLREKEQWKGKIILCIPCDEEGMMIGIKHFIQRGWAKGVDGAI
CCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCEE
ICEPEENQVCIAQKGAMRIVIRVYGKMAHGAIPLSGINPNTRMAKLICELEQLEKREKER
EECCCCCCEEEECCCCCEEHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LGKHPLLGWPSITPTILKAPVRGDAQINVIPDQCMTTLDIRTIPGQDHEELCEEIQRIFE
HCCCCCCCCCCCCHHHHCCCCCCCCEEEEEHHHHHEEEEEEECCCCCHHHHHHHHHHHHH
RLAEEDPDFKGEFEVIENRPWTKTSKDEPIVKAVAEAVRRVTKKEPYYNGVPGATDGTFL
HHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
HLEGIPIVTIGAGDREIPHQVDEYVDIDELAETTEIYRTAALLFLNEEV
EECCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]