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The map label for this gene is arlR [H]

Identifier: 138893961

GI number: 138893961

Start: 322879

End: 323541

Strand: Reverse

Name: arlR [H]

Synonym: GTNG_0285

Alternate gene names: 138893961

Gene position: 323541-322879 (Counterclockwise)

Preceding gene: 138893970

Following gene: 138893960

Centisome position: 9.11

GC content: 48.57

Gene sequence:

>663_bases
ATGAAAGTATTGCTCGCCGAAGATGATCTCCACTTATGGGAACTAATCGTCCATTTGTTAAAGAAAAAAGGGATTGACCA
TATCGACTGGGTACAAGAAGGAGAAGACGCGTACGACTACGCGATGGCGGAGTTTTACGATGTCGTCGTGCTCGATTGGA
TGCTCCCAAACGGCGATGGAGTCGATATTTGCCGACGATTGAGGCAAAATGGTTATACGGGCGCCATTTTGATACTGACG
GCAAAAGACGCAGTGCAAGACCGCGTCACCGGGCTTGAAGCTGGGGCGGATGATTATTTGGTTAAGCCGTTTGAAATTGA
TGAACTTGTTGCCCGCTTAAAAGCGCTCGCTCGGCGCACGTTCGTCCCGCTTCAAGAGGAAACAGTAACTTTTCACGGCT
TCACGTTGAATCGAACAAGCCATACGCTGCATCGCAATAATGAGGAAATTTCCCTTACCCCGCGCGAGTTTCAGCTTCTC
GATCTTCTCGTCCAAAACCAAGGCCAAGTTGTGCCGCGCGAGACGATCCTAGACCGCGTCTGGGGATGGGACGCTGATGT
ATCCATGAAAACGATTGACGCGACGATTAAATTGCTTCGTAAAAAGTTGAAAGACGATGTCATCCAAACGGTGCGGGGAG
TGGGATATAAAATTGATAAATAA

Upstream 100 bases:

>100_bases
GTCTCTTCGGAGTGACTCCTCCCTTCCCTTCTGATTTTCACCTTTTTTTCACGCATCTTTGTTATGATAAAAGAAATGAT
GGGAAACGGGAGGAACGGCC

Downstream 100 bases:

>100_bases
CTGGAACGAGTGGCGCCAATGGCTGCGCCGTTTAGGTAACGCGGACTTGTTCCGCCGCACTCATTGGCGGCTGACCGCGC
TTTATAGCGGCATTTTCACC

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKVLLAEDDLHLWELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDGVDICRRLRQNGYTGAILILT
AKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRTFVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLL
DLLVQNQGQVVPRETILDRVWGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK

Sequences:

>Translated_220_residues
MKVLLAEDDLHLWELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDGVDICRRLRQNGYTGAILILT
AKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRTFVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLL
DLLVQNQGQVVPRETILDRVWGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK
>Mature_220_residues
MKVLLAEDDLHLWELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDGVDICRRLRQNGYTGAILILT
AKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRTFVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLL
DLLVQNQGQVVPRETILDRVWGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=40.1826484018265, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=37.280701754386, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=39.4618834080717, Blast_Score=153, Evalue=7e-39,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=39.8190045248869, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=38.9908256880734, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=36.283185840708, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=37.5, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786911, Length=178, Percent_Identity=37.6404494382022, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1787229, Length=177, Percent_Identity=37.8531073446328, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=36.5638766519824, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.7354260089686, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=31.0344827586207, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=29.3103448275862, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788191, Length=115, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=28.125, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25269; Mature: 25269

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLAEDDLHLWELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDG
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCC
VDICRRLRQNGYTGAILILTAKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRT
HHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHH
FVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLLDLLVQNQGQVVPRETILDRV
CCCCCCCEEEEEEEEECCCCHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHH
WGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
>Mature Secondary Structure
MKVLLAEDDLHLWELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDG
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCC
VDICRRLRQNGYTGAILILTAKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRT
HHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHH
FVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLLDLLVQNQGQVVPRETILDRV
CCCCCCCEEEEEEEEECCCCHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHH
WGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA