Click here to switch to the map view.

The map label for this gene is yycG [H]

Identifier: 138893960

GI number: 138893960

Start: 321516

End: 322925

Strand: Reverse

Name: yycG [H]

Synonym: GTNG_0284

Alternate gene names: 138893960

Gene position: 322925-321516 (Counterclockwise)

Preceding gene: 138893961

Following gene: 138893959

Centisome position: 9.1

GC content: 53.97

Gene sequence:

>1410_bases
ATGTCATCCAAACGGTGCGGGGAGTGGGATATAAAATTGATAAATAACTGGAACGAGTGGCGCCAATGGCTGCGCCGTTT
AGGTAACGCGGACTTGTTCCGCCGCACTCATTGGCGGCTGACCGCGCTTTATAGCGGCATTTTCACCTTATTTCTCGCTT
TGTTTGTCGTTATTGCCGCCGCCTTGTTTTATTGGATCACGACATCCGAGCAAGAGCAGCGCATCACTCGCCTCGCCGAA
CAGGAGGCCAATACCATTGAACAGTTTTTGTTAAAACAAAGCAATTTTGACTTGTTCGATGACCAAAGTCTCGTGCTGTT
CAGCGAAGATCAACTCTTTTTTTACGTCATCAGCCCAACCGGCCGTCTGCTCGCCGGGGATGAAGTCCACCGGCGCCTGC
GCCCGTATTTTTTAAGCGCCTTGTCTCATCTGGACACGAACGAACAGACCCCAGTCTATCTGACCGTATCATTGCCTAAA
CATATGCCGGGCCTAGCCCGCGACGCTGCGCGTGATTGGCGAGTGCTCACCGCCGCCCACCCACTCGTCATTCGGGGAGA
TGTCGTCGGCATGCTTTATATCGGGATGGACGTGACATCGTTTTTTGGAGTATTTCATTGGCTGCTGATCGTGCTCATCG
GTCTTGCCATTCTGTTTCTCGCCGTCGGGGTGGCGCTTAGTTTCTTTATGTCCAAGCGAGCTCTCGTGCCGATTGAAGAA
GCGTACGAGCGGCAGCGCCAGTTTGTCGCCGACGCCTCGCATGAGTTGCGCACGCCGCTTAGTGTCGTCTTTTCATCGGT
TGAGGCGCTCACACTGGAAGAGGATGTGATGAAAAACGAATTGGCCCACCGTCTGCTCGATCGCCTTCGTGAAGAGTTGA
AGCGGATCACGAAGTTGATGAACGACCTCTTGACGCTCGCCCGCGCGGATGCAAAACATGCCGCGTTGGAGCTGGCGAAA
CAAACGTTTGACTTCCGCCCGCACGCTGAGCGAACATTCCAGCTCATCTCGGAGCTGGCAGCAAAAAAACAGATCACAAT
GAATTTTCACGCCCCGGAGCAGGCGATGGTGACAGCCGATCCGGACAAGTTGACGCAACTGCTGTACATTTTGCTTGATA
ACGCCATCAAATACACCCCAGAAGGCGGAAATGTGACGCTGTCGATTCGCACCGAACCGAAACAATTTGTCCTTTCCGTC
AAAGACACCGGCATCGGCATTCCGCCGGAAGATATCGGCCGGATTTTCGACCGCTTCTACCGTGTCGACAAAGCGCGCTC
CCGCCAACAAGGTGGCCACGGCCTGGGACTATCGATCGCCAAATGGATCGTTGACGCCCATGGTGGTACGATCCACGTTC
AAAGCCAACTCGGCCAAGGGACAGAATTTCTTGTCCTCCTGCCCGCTTAA

Upstream 100 bases:

>100_bases
CGCGAGACGATCCTAGACCGCGTCTGGGGATGGGACGCTGATGTATCCATGAAAACGATTGACGCGACGATTAAATTGCT
TCGTAAAAAGTTGAAAGACG

Downstream 100 bases:

>100_bases
CCCACAGCTTTTCTTATCACAACGAAAGGTGTCCCCTATAGAACGGGACACCTTTCATTCTCTATTCACAATCAGTTTAA
AAAGATTTCGCTTTTCACCT

Product: two component system histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSSKRCGEWDIKLINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAAALFYWITTSEQEQRITRLAE
QEANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPTGRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPK
HMPGLARDAARDWRVLTAAHPLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEE
AYERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLMNDLLTLARADAKHAALELAK
QTFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTADPDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSV
KDTGIGIPPEDIGRIFDRFYRVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA

Sequences:

>Translated_469_residues
MSSKRCGEWDIKLINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAAALFYWITTSEQEQRITRLAE
QEANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPTGRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPK
HMPGLARDAARDWRVLTAAHPLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEE
AYERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLMNDLLTLARADAKHAALELAK
QTFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTADPDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSV
KDTGIGIPPEDIGRIFDRFYRVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA
>Mature_468_residues
SSKRCGEWDIKLINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAAALFYWITTSEQEQRITRLAEQ
EANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPTGRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPKH
MPGLARDAARDWRVLTAAHPLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEEA
YERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLMNDLLTLARADAKHAALELAKQ
TFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTADPDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSVK
DTGIGIPPEDIGRIFDRFYRVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=34.8547717842324, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=36.6379310344828, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=34.1991341991342, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790436, Length=393, Percent_Identity=28.498727735369, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=32.2175732217573, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=29.7413793103448, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=28.8617886178862, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=32.3275862068966, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=192, Percent_Identity=35.4166666666667, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790346, Length=259, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789403, Length=211, Percent_Identity=30.8056872037915, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=28.936170212766, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=29.0748898678414, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790551, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=228, Percent_Identity=26.7543859649123, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=26.5486725663717, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=28.936170212766, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=90, Percent_Identity=42.2222222222222, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53491; Mature: 53359

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKRCGEWDIKLINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAA
CCCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFYWITTSEQEQRITRLAEQEANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEECCC
GRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPKHMPGLARDAARDWRVLTAAH
CCEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCCEEEEECC
PLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEE
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
AYERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLM
HHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDLLTLARADAKHAALELAKQTFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTAD
HHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCEEECC
PDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSVKDTGIGIPPEDIGRIFDRFY
HHHHHHHHHHHHHHHHEECCCCCCEEEEEECCHHHEEEEECCCCCCCCHHHHHHHHHHHH
RVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
SSKRCGEWDIKLINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAA
CCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFYWITTSEQEQRITRLAEQEANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEECCC
GRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPKHMPGLARDAARDWRVLTAAH
CCEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCCEEEEECC
PLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEE
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
AYERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLM
HHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDLLTLARADAKHAALELAKQTFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTAD
HHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCEEECC
PDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSVKDTGIGIPPEDIGRIFDRFY
HHHHHHHHHHHHHHHHEECCCCCCEEEEEECCHHHEEEEECCCCCCCCHHHHHHHHHHHH
RVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]