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The map label for this gene is ade [C]

Identifier: 138893926

GI number: 138893926

Start: 278528

End: 280273

Strand: Direct

Name: ade [C]

Synonym: GTNG_0250

Alternate gene names: 138893926

Gene position: 278528-280273 (Clockwise)

Preceding gene: 138893924

Following gene: 138893927

Centisome position: 7.85

GC content: 50.97

Gene sequence:

>1746_bases
ATGGGCGAACAACGCTACCGATGGAAGAGCAGTGAATTGCGCGAACAAGCAGCGGTGATTGATGGCAAACGATCGCCGAC
AAAAGTATTGGTGAACGCAACGTATTTGCATTCTTATTTCCGTGAATGGGTAAAAGGGAATATATGGATACATGGCGACC
GTATTGTGTACGCCGGAGAGCGGCTTCCTGATCGCATCGATGAGTCATGCGAAATCATCGACTGCCGTGGGTATGTGCTC
GTCCCCGGCTACATTGAGCCGCATGTTCATCCATTTCAATTATATAATCCCCATTCATTTGCACGTTATGCAGCAATGTA
CGGGACGACGACGCTGCTCAACGATAATTTATTTTTCCTTTTGCAGCTTGACGATGAAGAGGCGCTTTTATTTTTGCAAG
AAATGAATGCGCTTCCAACATCCATGTATTGGTGGTGCCGATTTGACGGGCAAACGGAGCTAGAGCGCGAAGATGAGCAG
ATATCGAACGCCCGGATCAAACGGTGGTTGGATCAAGAAACGGTCCTTCAAGGCGGTGAGCTGACGTCATGGCCTAAGCT
CGCAAGTGGCGACGATATCGTCCTTTACTGGATGCAAGAGGCGAAACGGCGGCGCCGTAAAATCGAGGGGCACTTTCCCG
GTGCTTCAGAGAAAACGCTGGTGAAAATGGCGCTGTTTGGTGTAGACGGAGATCATGAGGCGATGACAGGAAAAGAAGTG
CGTCTTCGCCTTTGGCACGGCTATACAGTCACGCTTCGCCATTCATCGATCCGTCCGGATTTGCCGGTGCTGCTTGAGGA
AATGAAAGCGCTTGGCATTCGGTATTATGACAAGTGCTTATTGACGACCGACGGCTCGCCACCGGCCTTTTATGAAAACG
GGGTAATGGATCAGCTGCTTCGCATCGTCATCGAGCATGGTGTGCCAGTTATCGATGCATACGCCATGGCGACGATTAAT
GCCGCCCGTCATTACGGCATTGAGCATCTTCACGGCAGCATCGCTACCGGCCGGATCGCGCACATCAACTTCTTGCGTTC
GGCCCATGATCCAACGCCAGTACAGGTGCTCGCCAAGGGCGAATGGGTGAAGCGTGAAGGGGATTCGTCAGGCTCATGGC
CGGCGCTGAAGTGGGAACAGTTTGGCATTCGTCCGCTTTCAGTGTCATGGGAGCTTGAATGGGACGATTTGCAATTTTCG
ATGCCGATGGGGTTGCGACTGGAAAATGCGGTGATTGTAAAGCCGTACTCCGTGTCGATTGATACGTCGCGCGACCGTTT
AGGGCATGATCATGACGAATGCTTTTTAATGCTGCTTGACCGAAACGGCTGCTGGCGCGTCAACACAATGCTCAAAGGAT
TTTCATCAGCGCTCGGCGGGCTGGCGAGTTCGTATTCGAACACTGGCGATTTCATCTTAATTGGCAAACATAAAGAAGAT
ATGATGCTTGCCTTCCGACGGATGAAGGATATCGGCGGCGGCATCGTACTCGTGGAGGACGGAAACGTTTTATTTGAGCT
TCCGCTTCCGCTTAGCGGCATGACGTCTACCTTGGAGATGGAAACATTAATCAATGAGGAAAAGACATTTGTCCGCCTTT
TGCGGGAGCGCGGGTATTATTTTGAGGATCCGGTATACTCGTTGTTCTTTTTACAGTCGACCCATTTGCCATACGTGCGC
ATCACCCAGCGCGGCATTTATGATGTCATGCACAAAACGGTACTCTTTCCTTCGATAATGCGGTAA

Upstream 100 bases:

>100_bases
CGCCATTGGCATGTCCCTCCTCATATTTTTATTGTGAAAATCGCTTTCGTGCGTTAAAATGATTATATGGAACGATTAGG
AAACAAGGGACGGGGTGTCA

Downstream 100 bases:

>100_bases
AATAAAAAAGGAAAAGGTTGTGTGTCCATTGAAACATTGGCTGTTTGTCATCAGTTGCGCAGTGCTGTTACTAGGCGGCT
GCACCGCCAAAAGCGAGCCG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MGEQRYRWKSSELREQAAVIDGKRSPTKVLVNATYLHSYFREWVKGNIWIHGDRIVYAGERLPDRIDESCEIIDCRGYVL
VPGYIEPHVHPFQLYNPHSFARYAAMYGTTTLLNDNLFFLLQLDDEEALLFLQEMNALPTSMYWWCRFDGQTELEREDEQ
ISNARIKRWLDQETVLQGGELTSWPKLASGDDIVLYWMQEAKRRRRKIEGHFPGASEKTLVKMALFGVDGDHEAMTGKEV
RLRLWHGYTVTLRHSSIRPDLPVLLEEMKALGIRYYDKCLLTTDGSPPAFYENGVMDQLLRIVIEHGVPVIDAYAMATIN
AARHYGIEHLHGSIATGRIAHINFLRSAHDPTPVQVLAKGEWVKREGDSSGSWPALKWEQFGIRPLSVSWELEWDDLQFS
MPMGLRLENAVIVKPYSVSIDTSRDRLGHDHDECFLMLLDRNGCWRVNTMLKGFSSALGGLASSYSNTGDFILIGKHKED
MMLAFRRMKDIGGGIVLVEDGNVLFELPLPLSGMTSTLEMETLINEEKTFVRLLRERGYYFEDPVYSLFFLQSTHLPYVR
ITQRGIYDVMHKTVLFPSIMR

Sequences:

>Translated_581_residues
MGEQRYRWKSSELREQAAVIDGKRSPTKVLVNATYLHSYFREWVKGNIWIHGDRIVYAGERLPDRIDESCEIIDCRGYVL
VPGYIEPHVHPFQLYNPHSFARYAAMYGTTTLLNDNLFFLLQLDDEEALLFLQEMNALPTSMYWWCRFDGQTELEREDEQ
ISNARIKRWLDQETVLQGGELTSWPKLASGDDIVLYWMQEAKRRRRKIEGHFPGASEKTLVKMALFGVDGDHEAMTGKEV
RLRLWHGYTVTLRHSSIRPDLPVLLEEMKALGIRYYDKCLLTTDGSPPAFYENGVMDQLLRIVIEHGVPVIDAYAMATIN
AARHYGIEHLHGSIATGRIAHINFLRSAHDPTPVQVLAKGEWVKREGDSSGSWPALKWEQFGIRPLSVSWELEWDDLQFS
MPMGLRLENAVIVKPYSVSIDTSRDRLGHDHDECFLMLLDRNGCWRVNTMLKGFSSALGGLASSYSNTGDFILIGKHKED
MMLAFRRMKDIGGGIVLVEDGNVLFELPLPLSGMTSTLEMETLINEEKTFVRLLRERGYYFEDPVYSLFFLQSTHLPYVR
ITQRGIYDVMHKTVLFPSIMR
>Mature_580_residues
GEQRYRWKSSELREQAAVIDGKRSPTKVLVNATYLHSYFREWVKGNIWIHGDRIVYAGERLPDRIDESCEIIDCRGYVLV
PGYIEPHVHPFQLYNPHSFARYAAMYGTTTLLNDNLFFLLQLDDEEALLFLQEMNALPTSMYWWCRFDGQTELEREDEQI
SNARIKRWLDQETVLQGGELTSWPKLASGDDIVLYWMQEAKRRRRKIEGHFPGASEKTLVKMALFGVDGDHEAMTGKEVR
LRLWHGYTVTLRHSSIRPDLPVLLEEMKALGIRYYDKCLLTTDGSPPAFYENGVMDQLLRIVIEHGVPVIDAYAMATINA
ARHYGIEHLHGSIATGRIAHINFLRSAHDPTPVQVLAKGEWVKREGDSSGSWPALKWEQFGIRPLSVSWELEWDDLQFSM
PMGLRLENAVIVKPYSVSIDTSRDRLGHDHDECFLMLLDRNGCWRVNTMLKGFSSALGGLASSYSNTGDFILIGKHKEDM
MLAFRRMKDIGGGIVLVEDGNVLFELPLPLSGMTSTLEMETLINEEKTFVRLLRERGYYFEDPVYSLFFLQSTHLPYVRI
TQRGIYDVMHKTVLFPSIMR

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=583, Percent_Identity=26.2435677530017, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 66887; Mature: 66755

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEQRYRWKSSELREQAAVIDGKRSPTKVLVNATYLHSYFREWVKGNIWIHGDRIVYAGE
CCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCEEEECCEEEECCC
RLPDRIDESCEIIDCRGYVLVPGYIEPHVHPFQLYNPHSFARYAAMYGTTTLLNDNLFFL
CCCHHHCCCCCEEEECCEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCEEEECCCEEEE
LQLDDEEALLFLQEMNALPTSMYWWCRFDGQTELEREDEQISNARIKRWLDQETVLQGGE
EEECCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCC
LTSWPKLASGDDIVLYWMQEAKRRRRKIEGHFPGASEKTLVKMALFGVDGDHEAMTGKEV
CCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEE
RLRLWHGYTVTLRHSSIRPDLPVLLEEMKALGIRYYDKCLLTTDGSPPAFYENGVMDQLL
EEEEEECEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHCCCHHHHHH
RIVIEHGVPVIDAYAMATINAARHYGIEHLHGSIATGRIAHINFLRSAHDPTPVQVLAKG
HHHHHCCCCEEEHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEEHHHHCCCCCCEEEEECC
EWVKREGDSSGSWPALKWEQFGIRPLSVSWELEWDDLQFSMPMGLRLENAVIVKPYSVSI
CEEECCCCCCCCCCEEEHHHCCCEEEEEEEEEEECCEEEECCCCEEECCEEEEEEEEEEE
DTSRDRLGHDHDECFLMLLDRNGCWRVNTMLKGFSSALGGLASSYSNTGDFILIGKHKED
ECCHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHH
MMLAFRRMKDIGGGIVLVEDGNVLFELPLPLSGMTSTLEMETLINEEKTFVRLLRERGYY
HHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCE
FEDPVYSLFFLQSTHLPYVRITQRGIYDVMHKTVLFPSIMR
ECCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GEQRYRWKSSELREQAAVIDGKRSPTKVLVNATYLHSYFREWVKGNIWIHGDRIVYAGE
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCEEEECCEEEECCC
RLPDRIDESCEIIDCRGYVLVPGYIEPHVHPFQLYNPHSFARYAAMYGTTTLLNDNLFFL
CCCHHHCCCCCEEEECCEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCEEEECCCEEEE
LQLDDEEALLFLQEMNALPTSMYWWCRFDGQTELEREDEQISNARIKRWLDQETVLQGGE
EEECCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCC
LTSWPKLASGDDIVLYWMQEAKRRRRKIEGHFPGASEKTLVKMALFGVDGDHEAMTGKEV
CCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEE
RLRLWHGYTVTLRHSSIRPDLPVLLEEMKALGIRYYDKCLLTTDGSPPAFYENGVMDQLL
EEEEEECEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHCCCHHHHHH
RIVIEHGVPVIDAYAMATINAARHYGIEHLHGSIATGRIAHINFLRSAHDPTPVQVLAKG
HHHHHCCCCEEEHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEEHHHHCCCCCCEEEEECC
EWVKREGDSSGSWPALKWEQFGIRPLSVSWELEWDDLQFSMPMGLRLENAVIVKPYSVSI
CEEECCCCCCCCCCEEEHHHCCCEEEEEEEEEEECCEEEECCCCEEECCEEEEEEEEEEE
DTSRDRLGHDHDECFLMLLDRNGCWRVNTMLKGFSSALGGLASSYSNTGDFILIGKHKED
ECCHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHH
MMLAFRRMKDIGGGIVLVEDGNVLFELPLPLSGMTSTLEMETLINEEKTFVRLLRERGYY
HHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCE
FEDPVYSLFFLQSTHLPYVRITQRGIYDVMHKTVLFPSIMR
ECCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]