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The map label for this gene is purL [H]

Identifier: 138893918

GI number: 138893918

Start: 269098

End: 269784

Strand: Direct

Name: purL [H]

Synonym: GTNG_0242

Alternate gene names: 138893918

Gene position: 269098-269784 (Clockwise)

Preceding gene: 138893917

Following gene: 138893919

Centisome position: 7.58

GC content: 52.98

Gene sequence:

>687_bases
ATGAAGTTTGCCGTCATTGTGTTTCCTGGATCGAATTGTGATGTCGATATGTACCATGCGATCGCCGATGAGCTCGGTGA
AGAAGTGGAATACGTTTGGCATGATGAAGAGAATCTCGATCGTTTTGACGCCATTTTGCTTCCAGGCGGTTTTTCGTACG
GAGATTACTTGCGTTCGGGGGCGATCGCCCGTTTTTCCAAGGTGATGGCCGCCGTGAAACAAGCCGCGGAAGCCGGGAAA
CCCGTGCTTGGGGTGTGCAACGGATTTCAAATTTTGCTTGAAGCCGGCTTGCTTCCTGGGGCGATGCGCCGCAACCAAGG
ACTGAAATTCATTTGCCGGCCGGTGCAGCTTGTGGTGGAAAACAATGAAACGATGTTTACCTCTGCCTACGGAAAAGACG
AAGTGATCACCATTCCGATCGCCCATGGCGAAGGGAACTATTATTGCGACGAGCAAACGCTCAATCGCCTCGTCGAAAAC
CGGCAAATCGTCTTCCGCTATCATGGGGAAAACCCGAACGGTAGCTTGGCGGATATTGCTGGCATCGTCAATGAGCGCGG
TAATGTACTTGGTATGATGCCGCATCCGGAGCGGGCCGTCGACGCCTTGCTCGGCAGCGCGGACGGACTGAAACTATTCC
GATCGATCGTCAACTATTGGAGGGAGACGCATGTCGTTACTGCTTGA

Upstream 100 bases:

>100_bases
GTCGCGATATCGATAAGCTTGTTCGTGAGATGTGTGAAAAATTGTTGTCTAACCCGGTCATTGAAGACTATCGCTATGAA
ATTGAGGAGGCCGTCGCCCG

Downstream 100 bases:

>100_bases
GCCGAATGCGGCAATGATTAAAGAACAAAAATTGTATCGTGAAATGGGATTAACGGATGAGGAGTTTGCGCGCATTGAAG
CGATTTTGGGAAGACTGCCG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKFAVIVFPGSNCDVDMYHAIADELGEEVEYVWHDEENLDRFDAILLPGGFSYGDYLRSGAIARFSKVMAAVKQAAEAGK
PVLGVCNGFQILLEAGLLPGAMRRNQGLKFICRPVQLVVENNETMFTSAYGKDEVITIPIAHGEGNYYCDEQTLNRLVEN
RQIVFRYHGENPNGSLADIAGIVNERGNVLGMMPHPERAVDALLGSADGLKLFRSIVNYWRETHVVTA

Sequences:

>Translated_228_residues
MKFAVIVFPGSNCDVDMYHAIADELGEEVEYVWHDEENLDRFDAILLPGGFSYGDYLRSGAIARFSKVMAAVKQAAEAGK
PVLGVCNGFQILLEAGLLPGAMRRNQGLKFICRPVQLVVENNETMFTSAYGKDEVITIPIAHGEGNYYCDEQTLNRLVEN
RQIVFRYHGENPNGSLADIAGIVNERGNVLGMMPHPERAVDALLGSADGLKLFRSIVNYWRETHVVTA
>Mature_228_residues
MKFAVIVFPGSNCDVDMYHAIADELGEEVEYVWHDEENLDRFDAILLPGGFSYGDYLRSGAIARFSKVMAAVKQAAEAGK
PVLGVCNGFQILLEAGLLPGAMRRNQGLKFICRPVQLVVENNETMFTSAYGKDEVITIPIAHGEGNYYCDEQTLNRLVEN
RQIVFRYHGENPNGSLADIAGIVNERGNVLGMMPHPERAVDALLGSADGLKLFRSIVNYWRETHVVTA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=246, Percent_Identity=28.4552845528455, Blast_Score=64, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321498, Length=197, Percent_Identity=30.9644670050761, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24582111, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582109, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17137292, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25225; Mature: 25225

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIVFPGSNCDVDMYHAIADELGEEVEYVWHDEENLDRFDAILLPGGFSYGDYLRSG
CEEEEEEECCCCCCHHHHHHHHHHHCHHHEEEECCCCCCCHHCEEEECCCCCHHHHHHHC
AIARFSKVMAAVKQAAEAGKPVLGVCNGFQILLEAGLLPGAMRRNQGLKFICRPVQLVVE
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEEE
NNETMFTSAYGKDEVITIPIAHGEGNYYCDEQTLNRLVENRQIVFRYHGENPNGSLADIA
CCCEEEEECCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
GIVNERGNVLGMMPHPERAVDALLGSADGLKLFRSIVNYWRETHVVTA
HHHHCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFAVIVFPGSNCDVDMYHAIADELGEEVEYVWHDEENLDRFDAILLPGGFSYGDYLRSG
CEEEEEEECCCCCCHHHHHHHHHHHCHHHEEEECCCCCCCHHCEEEECCCCCHHHHHHHC
AIARFSKVMAAVKQAAEAGKPVLGVCNGFQILLEAGLLPGAMRRNQGLKFICRPVQLVVE
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEEE
NNETMFTSAYGKDEVITIPIAHGEGNYYCDEQTLNRLVENRQIVFRYHGENPNGSLADIA
CCCEEEEECCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
GIVNERGNVLGMMPHPERAVDALLGSADGLKLFRSIVNYWRETHVVTA
HHHHCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA