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The map label for this gene is phoP [H]

Identifier: 138893859

GI number: 138893859

Start: 196252

End: 196938

Strand: Reverse

Name: phoP [H]

Synonym: GTNG_0183

Alternate gene names: 138893859

Gene position: 196938-196252 (Counterclockwise)

Preceding gene: 138893865

Following gene: 138893858

Centisome position: 5.55

GC content: 47.6

Gene sequence:

>687_bases
ATGCCTCACACGTTATTATTAGTGGATGATGAAGAAAGAGTCCTTGAATTTATGGAGCCCTTTTTGCGACAGGAAGGATT
TGAAATTGTCACAGCCAAAACGGGAAAGGAAGCGCTGCAAAAAGCAAAAGAAACCAATCCATCCCTTGTGGTGCTTGATT
GGATGCTTCCTGAAATGAGCGGGATTGATGTGTGCCGCGAACTTCGTAAGACGAGCCATGTTGGAATCATCATGGTCACA
GCAAAGACAGAGGAAACTGACAAAATCATTGGCCTAGAGGTGGGAGCTGATGATTACATCACCAAACCTTTTTCCCTGAG
GGAACTGGCAGCCCGCATTCGCTCCGTATTGCGGCGAATCGAAGGGCAAGACAATCAGGAGGAACTGATGAAACGCGGCG
ACTTGACCATTTCTGAAGCGCAATGCCGCGTATGGAAACGAGGAAGCGAAATCTCCTTAACGCCGACCGAATTTAAGCTG
CTGCTCACTCTAGCGGCAAAGCCAGGTGTCGTATATAGCCGGCTGCAGCTGTTGCAAAGCATTTTTGAAGATGACCTTTT
CAACGATGAACGAACTGTCGATGCTCATATCAGCCGGCTTCGTAAAAAGATTGAAGATGATCCGTCCCGTCCAGTCTATA
TCCAAACTGTCTATGGATTCGGCTATCGGTTCGGTGAGCAGATATGA

Upstream 100 bases:

>100_bases
AACTAATGACGAACTTTTGCAGGTTTAGTGACATTTTCCTAAATCTGTCCATATGGGGCTATAATGAAAAGAGAACAGAA
CAAACAAGGGGGAACAAGAT

Downstream 100 bases:

>100_bases
GCATCAGGCGTAAGCTGTTTTTTACAATGGCCGTCTTTATTATCGGCATGGGAATCATGTTTTCCCTCATCACCAAGGTG
GTCGTCATCAATATACTGGA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPHTLLLVDDEERVLEFMEPFLRQEGFEIVTAKTGKEALQKAKETNPSLVVLDWMLPEMSGIDVCRELRKTSHVGIIMVT
AKTEETDKIIGLEVGADDYITKPFSLRELAARIRSVLRRIEGQDNQEELMKRGDLTISEAQCRVWKRGSEISLTPTEFKL
LLTLAAKPGVVYSRLQLLQSIFEDDLFNDERTVDAHISRLRKKIEDDPSRPVYIQTVYGFGYRFGEQI

Sequences:

>Translated_228_residues
MPHTLLLVDDEERVLEFMEPFLRQEGFEIVTAKTGKEALQKAKETNPSLVVLDWMLPEMSGIDVCRELRKTSHVGIIMVT
AKTEETDKIIGLEVGADDYITKPFSLRELAARIRSVLRRIEGQDNQEELMKRGDLTISEAQCRVWKRGSEISLTPTEFKL
LLTLAAKPGVVYSRLQLLQSIFEDDLFNDERTVDAHISRLRKKIEDDPSRPVYIQTVYGFGYRFGEQI
>Mature_227_residues
PHTLLLVDDEERVLEFMEPFLRQEGFEIVTAKTGKEALQKAKETNPSLVVLDWMLPEMSGIDVCRELRKTSHVGIIMVTA
KTEETDKIIGLEVGADDYITKPFSLRELAARIRSVLRRIEGQDNQEELMKRGDLTISEAQCRVWKRGSEISLTPTEFKLL
LTLAAKPGVVYSRLQLLQSIFEDDLFNDERTVDAHISRLRKKIEDDPSRPVYIQTVYGFGYRFGEQI

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=40.9090909090909, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=41.8502202643172, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=40.3508771929825, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=38.2882882882883, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=37.7272727272727, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=36.3636363636364, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=37.5, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=36.986301369863, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=34.0909090909091, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=34.8214285714286, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=31.3807531380753, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=29.8642533936652, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788550, Length=153, Percent_Identity=30.0653594771242, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790437, Length=208, Percent_Identity=23.5576923076923, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=27.5, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26160; Mature: 26029

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTLLLVDDEERVLEFMEPFLRQEGFEIVTAKTGKEALQKAKETNPSLVVLDWMLPEMS
CCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCC
GIDVCRELRKTSHVGIIMVTAKTEETDKIIGLEVGADDYITKPFSLRELAARIRSVLRRI
HHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
EGQDNQEELMKRGDLTISEAQCRVWKRGSEISLTPTEFKLLLTLAAKPGVVYSRLQLLQS
CCCCCHHHHHHHCCCEEEHHHHHHHCCCCCEEECHHHHEEEEEECCCCCHHHHHHHHHHH
IFEDDLFNDERTVDAHISRLRKKIEDDPSRPVYIQTVYGFGYRFGEQI
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHCCCC
>Mature Secondary Structure 
PHTLLLVDDEERVLEFMEPFLRQEGFEIVTAKTGKEALQKAKETNPSLVVLDWMLPEMS
CCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCC
GIDVCRELRKTSHVGIIMVTAKTEETDKIIGLEVGADDYITKPFSLRELAARIRSVLRRI
HHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
EGQDNQEELMKRGDLTISEAQCRVWKRGSEISLTPTEFKLLLTLAAKPGVVYSRLQLLQS
CCCCCHHHHHHHCCCEEEHHHHHHHCCCCCEEECHHHHEEEEEECCCCCHHHHHHHHHHH
IFEDDLFNDERTVDAHISRLRKKIEDDPSRPVYIQTVYGFGYRFGEQI
HHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]