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The map label for this gene is baeS [H]

Identifier: 138893858

GI number: 138893858

Start: 194924

End: 196255

Strand: Reverse

Name: baeS [H]

Synonym: GTNG_0182

Alternate gene names: 138893858

Gene position: 196255-194924 (Counterclockwise)

Preceding gene: 138893859

Following gene: 138893857

Centisome position: 5.53

GC content: 50.75

Gene sequence:

>1332_bases
ATGAGCATCAGGCGTAAGCTGTTTTTTACAATGGCCGTCTTTATTATCGGCATGGGAATCATGTTTTCCCTCATCACCAA
GGTGGTCGTCATCAATATACTGGACGTGATGCTAAAGGTTGATCGAAGTCACGAAACGAACGAACTGGCAACTGCTTTTG
CTCATTATTACGAAACGCACCATCGCTCTTGGAACGGCATCCAACACATCCGCCTCAACACGGATATCATGAAAAAACAT
GAACAAGCTGGGGTGGTTCTTCTATCTCCCGAGGGCAAGCAGCTATATACAACGGGGGAAGTTCCAGTGTCATGGATGAT
TGGTCTAGGTATCTCTACCAAGGTGCAAGCAGATGGAAAAACTGTAGCGTTTTTGCACTACTACGACCATGAAGTCGGCA
ATATGGCCAAAGTGCGGAAGGGAATCACAAGTTCAGTCGCCACTTTATCCTTGCTCAGCGCTGCCGCGTTAGTGCTTATT
TCCCTCTTCGTCGCCCATTGGCTGTCGAAACGGTTCACAGCACCGCTCGAGCTTCTCCTGCCTGCGATTGACCGTCTCGG
AAAAGGGGAATTCGGCATTCAGGCACCGGTGATCACGAAAGATGAATACGGCAAAGTCGCCCAAACGTTCAACGAGATGT
CCAAACAGTTGCAGCAAGCGGAGGAAGTTCGCCGACGCTTGATGGCCGATGTCGCCCATGAACTGCGAACCCCCCTAACG
ATCTTGCGCGGAAAGCTTGATTGGTTTCAGCAACAACGCCGCCCCATCGAGCCGGAGAAATTGCTGCCGCTACAAGATGA
GCTCATTCGGTTGACTCGTCTCGTAGAAGATTTGCATCAACTGTCACTCGCCGAAGCTGGCAAATTGCCGCTTGAACGGA
AACCAACAGATATGGAAAGTCTTTTGCAACAACTCATCGAGCGGGTAGCTCCCAGCGCGGAAGAAAAAAACATCCGCATC
CATCTAACTTGTTCGACAAACTACACAACGATCTCCGTCGATCCGCATCGCATTACCCAAGTATTCCTGAACTTGTTGGT
CAATGCGATCCGCTATACTCCTGAAGGCGGCACGGTGAACGTGGTGATTGACGAAGAACCTTCCATGCTGCAAATTGCCG
TTACAGATACGGGCATCGGCATTGCACCGGAGCATTTGCCTTTTCTGTTCCATCGATTTTATCGCACGGATGAAGCCAGA
ACACGGAACCGCGGAGGAACGGGACTGGGGCTGGCTATCGCTAACGAATTCGTATCAGCTCATGGCGGAACCATCGACGT
CCATAGCACTCCTGGCCAAGGGACTACCTTTCTAGTCAAGCTTCCTCGCTGA

Upstream 100 bases:

>100_bases
CTCATATCAGCCGGCTTCGTAAAAAGATTGAAGATGATCCGTCCCGTCCAGTCTATATCCAAACTGTCTATGGATTCGGC
TATCGGTTCGGTGAGCAGAT

Downstream 100 bases:

>100_bases
CGATAAAGAGGACGTTTATGGTAGAATGGAAAACAGGAATCCATAACCAAAAGGAGGAATCGCTATGCCCCGCGCACAAC
AATGGGTGCAATATTTCCTT

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSIRRKLFFTMAVFIIGMGIMFSLITKVVVINILDVMLKVDRSHETNELATAFAHYYETHHRSWNGIQHIRLNTDIMKKH
EQAGVVLLSPEGKQLYTTGEVPVSWMIGLGISTKVQADGKTVAFLHYYDHEVGNMAKVRKGITSSVATLSLLSAAALVLI
SLFVAHWLSKRFTAPLELLLPAIDRLGKGEFGIQAPVITKDEYGKVAQTFNEMSKQLQQAEEVRRRLMADVAHELRTPLT
ILRGKLDWFQQQRRPIEPEKLLPLQDELIRLTRLVEDLHQLSLAEAGKLPLERKPTDMESLLQQLIERVAPSAEEKNIRI
HLTCSTNYTTISVDPHRITQVFLNLLVNAIRYTPEGGTVNVVIDEEPSMLQIAVTDTGIGIAPEHLPFLFHRFYRTDEAR
TRNRGGTGLGLAIANEFVSAHGGTIDVHSTPGQGTTFLVKLPR

Sequences:

>Translated_443_residues
MSIRRKLFFTMAVFIIGMGIMFSLITKVVVINILDVMLKVDRSHETNELATAFAHYYETHHRSWNGIQHIRLNTDIMKKH
EQAGVVLLSPEGKQLYTTGEVPVSWMIGLGISTKVQADGKTVAFLHYYDHEVGNMAKVRKGITSSVATLSLLSAAALVLI
SLFVAHWLSKRFTAPLELLLPAIDRLGKGEFGIQAPVITKDEYGKVAQTFNEMSKQLQQAEEVRRRLMADVAHELRTPLT
ILRGKLDWFQQQRRPIEPEKLLPLQDELIRLTRLVEDLHQLSLAEAGKLPLERKPTDMESLLQQLIERVAPSAEEKNIRI
HLTCSTNYTTISVDPHRITQVFLNLLVNAIRYTPEGGTVNVVIDEEPSMLQIAVTDTGIGIAPEHLPFLFHRFYRTDEAR
TRNRGGTGLGLAIANEFVSAHGGTIDVHSTPGQGTTFLVKLPR
>Mature_442_residues
SIRRKLFFTMAVFIIGMGIMFSLITKVVVINILDVMLKVDRSHETNELATAFAHYYETHHRSWNGIQHIRLNTDIMKKHE
QAGVVLLSPEGKQLYTTGEVPVSWMIGLGISTKVQADGKTVAFLHYYDHEVGNMAKVRKGITSSVATLSLLSAAALVLIS
LFVAHWLSKRFTAPLELLLPAIDRLGKGEFGIQAPVITKDEYGKVAQTFNEMSKQLQQAEEVRRRLMADVAHELRTPLTI
LRGKLDWFQQQRRPIEPEKLLPLQDELIRLTRLVEDLHQLSLAEAGKLPLERKPTDMESLLQQLIERVAPSAEEKNIRIH
LTCSTNYTTISVDPHRITQVFLNLLVNAIRYTPEGGTVNVVIDEEPSMLQIAVTDTGIGIAPEHLPFLFHRFYRTDEART
RNRGGTGLGLAIANEFVSAHGGTIDVHSTPGQGTTFLVKLPR

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=36.996336996337, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=36.7965367965368, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786783, Length=295, Percent_Identity=29.8305084745763, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=35.5648535564854, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=30.4166666666667, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=31.304347826087, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=30, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994928, Length=287, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=29.1139240506329, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787894, Length=298, Percent_Identity=26.510067114094, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789808, Length=293, Percent_Identity=31.0580204778157, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788713, Length=238, Percent_Identity=28.1512605042017, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=28.5106382978723, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=230, Percent_Identity=29.1304347826087, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788279, Length=246, Percent_Identity=28.8617886178862, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789403, Length=305, Percent_Identity=27.8688524590164, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=25.085910652921, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=253, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790551, Length=296, Percent_Identity=26.3513513513513, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790300, Length=244, Percent_Identity=30.327868852459, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787374, Length=277, Percent_Identity=26.3537906137184, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49716; Mature: 49585

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRRKLFFTMAVFIIGMGIMFSLITKVVVINILDVMLKVDRSHETNELATAFAHYYETH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HRSWNGIQHIRLNTDIMKKHEQAGVVLLSPEGKQLYTTGEVPVSWMIGLGISTKVQADGK
CCCCCCEEEEEECHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEEEECCCCEEEECCCC
TVAFLHYYDHEVGNMAKVRKGITSSVATLSLLSAAALVLISLFVAHWLSKRFTAPLELLL
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PAIDRLGKGEFGIQAPVITKDEYGKVAQTFNEMSKQLQQAEEVRRRLMADVAHELRTPLT
HHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILRGKLDWFQQQRRPIEPEKLLPLQDELIRLTRLVEDLHQLSLAEAGKLPLERKPTDMES
HHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LLQQLIERVAPSAEEKNIRIHLTCSTNYTTISVDPHRITQVFLNLLVNAIRYTPEGGTVN
HHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEE
VVIDEEPSMLQIAVTDTGIGIAPEHLPFLFHRFYRTDEARTRNRGGTGLGLAIANEFVSA
EEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHC
HGGTIDVHSTPGQGTTFLVKLPR
CCCEEEEECCCCCCCEEEEECCC
>Mature Secondary Structure 
SIRRKLFFTMAVFIIGMGIMFSLITKVVVINILDVMLKVDRSHETNELATAFAHYYETH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HRSWNGIQHIRLNTDIMKKHEQAGVVLLSPEGKQLYTTGEVPVSWMIGLGISTKVQADGK
CCCCCCEEEEEECHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEEEECCCCEEEECCCC
TVAFLHYYDHEVGNMAKVRKGITSSVATLSLLSAAALVLISLFVAHWLSKRFTAPLELLL
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PAIDRLGKGEFGIQAPVITKDEYGKVAQTFNEMSKQLQQAEEVRRRLMADVAHELRTPLT
HHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILRGKLDWFQQQRRPIEPEKLLPLQDELIRLTRLVEDLHQLSLAEAGKLPLERKPTDMES
HHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LLQQLIERVAPSAEEKNIRIHLTCSTNYTTISVDPHRITQVFLNLLVNAIRYTPEGGTVN
HHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEE
VVIDEEPSMLQIAVTDTGIGIAPEHLPFLFHRFYRTDEARTRNRGGTGLGLAIANEFVSA
EEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHC
HGGTIDVHSTPGQGTTFLVKLPR
CCCEEEEECCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]