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The map label for this gene is fhuD [H]

Identifier: 138893850

GI number: 138893850

Start: 187158

End: 188084

Strand: Reverse

Name: fhuD [H]

Synonym: GTNG_0174

Alternate gene names: 138893850

Gene position: 188084-187158 (Counterclockwise)

Preceding gene: 138893851

Following gene: 138893849

Centisome position: 5.3

GC content: 43.37

Gene sequence:

>927_bases
ATGAGGAAAGCATGGCTGTCATTGTTGCTTCTTTTTACGCTCCTGTTAAGCGCCTGCGGCAATGCGGCGGACGACAACAA
GAAAAATAACGCTTCACCGGAGGAGAAAAAGCCGGAAACGATTACGTATCAGTCGGAAAACGGGGAAGTAGAAGTACCGG
CTGATCCGAAACGGGTCGTCGTCTTATCAACGTTTGCCGGGCATGTACTTGCCTTAGACGTTCCGATCGTCGGTGTCGAT
TCATGGTCGAAAATGAATCCGCTCTTTGAAGAAAAATTGAAAGACGCGGATGTCGTGACAGACGAAGACATTGAAAAAAT
TATGGCGTTAAAACCGGACTTAATTATCGGATTATCCAATACGAAAAACGTCGACAAATTAAGCAAAATCGCTCCGACCG
TCACCTTTACATACGGAAAGGTCGATTATTTAACACAGTTTTTAGAAATTGGTAAACTGTTAAATAAAGAAAAAGAAGCG
AAAGCGTGGATTGACGACTTCAAACAACGTGCACAACAAGCTGGGGAAGAAATCCGGGCAAAAATTGGTGAAAACGCAAC
CGTCACCGTAGCCGAAAACTTTGATAAGCAGCTGTATGTGTTTGGCAATAACTGGGCGCGCGGCACGGAAATTTTGTATC
AAGAAATGAAGCTGAAAATGCCAAAAGCCGTGGAAGAACAAGCGCTCAAACCGGGCTATTACGCTGTTTCCCTTGAAGCA
TTGCCGCAGTTTGTCGGCGATTATCTCATCTTAAGTAAAAACGGCGACAACGACACATCGTTTATGGAAACGAATACGTT
TAAAAACATCCCTGCTGTGAAAAACGGTCATATGTTTGTCGCTGATGCTAAAGCGTTTTATTTCAACGACCCAATTACGT
TAGACTACCAGCTCGATTTCTTTAAAAAGCATTTTTTAGGCCAATAA

Upstream 100 bases:

>100_bases
TTCGCGATGTGTTTGGCATTGATGCTGACATCGGCCTCGACCCTCGGACGAACAAGCCGGTTTGTTTTACGTATCATTTG
CTGAAAGGAGTTTATTCATC

Downstream 100 bases:

>100_bases
TAATGATGAGACGGGGCGTTCACAAATAGTGAATGTCCCGTCCTTTCTTGTGAAAAAGGGGGAAACCGCCGATGGAAGCA
AACCGCCGGCTATGGCCGTT

Product: Iron compound ABC transporter iron compound-binding protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein D; Ferrichrome-binding protein; Iron(III)-hydroxamate-binding protein fhuD [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRKAWLSLLLLFTLLLSACGNAADDNKKNNASPEEKKPETITYQSENGEVEVPADPKRVVVLSTFAGHVLALDVPIVGVD
SWSKMNPLFEEKLKDADVVTDEDIEKIMALKPDLIIGLSNTKNVDKLSKIAPTVTFTYGKVDYLTQFLEIGKLLNKEKEA
KAWIDDFKQRAQQAGEEIRAKIGENATVTVAENFDKQLYVFGNNWARGTEILYQEMKLKMPKAVEEQALKPGYYAVSLEA
LPQFVGDYLILSKNGDNDTSFMETNTFKNIPAVKNGHMFVADAKAFYFNDPITLDYQLDFFKKHFLGQ

Sequences:

>Translated_308_residues
MRKAWLSLLLLFTLLLSACGNAADDNKKNNASPEEKKPETITYQSENGEVEVPADPKRVVVLSTFAGHVLALDVPIVGVD
SWSKMNPLFEEKLKDADVVTDEDIEKIMALKPDLIIGLSNTKNVDKLSKIAPTVTFTYGKVDYLTQFLEIGKLLNKEKEA
KAWIDDFKQRAQQAGEEIRAKIGENATVTVAENFDKQLYVFGNNWARGTEILYQEMKLKMPKAVEEQALKPGYYAVSLEA
LPQFVGDYLILSKNGDNDTSFMETNTFKNIPAVKNGHMFVADAKAFYFNDPITLDYQLDFFKKHFLGQ
>Mature_308_residues
MRKAWLSLLLLFTLLLSACGNAADDNKKNNASPEEKKPETITYQSENGEVEVPADPKRVVVLSTFAGHVLALDVPIVGVD
SWSKMNPLFEEKLKDADVVTDEDIEKIMALKPDLIIGLSNTKNVDKLSKIAPTVTFTYGKVDYLTQFLEIGKLLNKEKEA
KAWIDDFKQRAQQAGEEIRAKIGENATVTVAENFDKQLYVFGNNWARGTEILYQEMKLKMPKAVEEQALKPGYYAVSLEA
LPQFVGDYLILSKNGDNDTSFMETNTFKNIPAVKNGHMFVADAKAFYFNDPITLDYQLDFFKKHFLGQ

Specific function: Part of the ABC transporter complex fhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 34649; Mature: 34649

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAWLSLLLLFTLLLSACGNAADDNKKNNASPEEKKPETITYQSENGEVEVPADPKRVV
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCEEE
VLSTFAGHVLALDVPIVGVDSWSKMNPLFEEKLKDADVVTDEDIEKIMALKPDLIIGLSN
EEEECCCEEEEEECCEEECCCCHHCCHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECC
TKNVDKLSKIAPTVTFTYGKVDYLTQFLEIGKLLNKEKEAKAWIDDFKQRAQQAGEEIRA
CCCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KIGENATVTVAENFDKQLYVFGNNWARGTEILYQEMKLKMPKAVEEQALKPGYYAVSLEA
HHCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEHHH
LPQFVGDYLILSKNGDNDTSFMETNTFKNIPAVKNGHMFVADAKAFYFNDPITLDYQLDF
HHHHHCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEECEEEEECCCEEEEEEHHH
FKKHFLGQ
HHHHHCCC
>Mature Secondary Structure
MRKAWLSLLLLFTLLLSACGNAADDNKKNNASPEEKKPETITYQSENGEVEVPADPKRVV
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCEEE
VLSTFAGHVLALDVPIVGVDSWSKMNPLFEEKLKDADVVTDEDIEKIMALKPDLIIGLSN
EEEECCCEEEEEECCEEECCCCHHCCHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECC
TKNVDKLSKIAPTVTFTYGKVDYLTQFLEIGKLLNKEKEAKAWIDDFKQRAQQAGEEIRA
CCCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KIGENATVTVAENFDKQLYVFGNNWARGTEILYQEMKLKMPKAVEEQALKPGYYAVSLEA
HHCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEHHH
LPQFVGDYLILSKNGDNDTSFMETNTFKNIPAVKNGHMFVADAKAFYFNDPITLDYQLDF
HHHHHCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEECEEEEECCCEEEEEEHHH
FKKHFLGQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8388528; 9639930; 9384377 [H]